Claire Liefferinckx discusses her work with the Belgian Inflammatory Bowel Disease research and development group (BIRD) to capture real-world outcomes of ustekinumab treatment for Crohn’s disease, using a large national cohort of patients with a history of significant previous biologic exposure.
Dr Alka Potdar and Dr Janine Bilsborough discuss their paper analysing genetic and transcriptomic sub-classifiers of small bowel Crohn’s and the associated phenotypic characteristics.
Umakant Sharma reports his work linking prescription opioids with increased gut dysbiosis, alterations in epithelial tight junction function and colitis severity in 2 different murine models of colitis.