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3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn’s Disease 2016: Part 1: Diagnosis and Medical Management
Year: 2016
Source: JCC: ECCO Guidelines
Authors: Fernando Gomollón, Axel Dignass, Vito Annese, Herbert Tilg, Gert Van Assche, James O. Lindsay, Laurent Peyrin-Biroulet, Garret J. Cullen, Marco Daperno, Torsten Kucharzik, Florian Rieder, Sven Almer, Alessandro Armuzzi, Marcus Harbord, Jost Langhorst, Miquel Sans, Yehuda Chowers, Gionata Fiorino, Pascal Juillerat, Gerassimos J. Mantzaris, Fernando Rizzello, Stephan Vavricka, Paolo Gionchetti, on behalf of ECCO
Created: Thursday, 16 March 2017, 4:30 PM by Vesna Babaja
Last Modified: Thursday, 16 March 2017, 4:34 PM by Vesna Babaja

This paper is the first in a series of two publications relating to the European Crohn’s and Colitis Organisation [ECCO] evidence-based consensus on the diagnosis and management of Crohn’s disease and concerns the methodology of the consensus process, and the classification, diagnosis and medical management of active and quiescent Crohn’s disease. Surgical management as well as special situations including management of perianal Crohn’s disease of this ECCO Consensus are covered in a subsequent second paper [Gionchetti et al JCC 2016].

3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn’s Disease 2016: Part 2: Surgical Management and Special Situations
Year: 2016
Source: JCC: ECCO Guidelines
Authors: Paolo Gionchetti, Axel Dignass, Silvio Danese, Fernando José Magro Dias, Gerhard Rogler, Péter Laszlo Lakatos, Michel Adamina, Sandro Ardizzone, Christianne J. Buskens, Shaji Sebastian, Silvio Laureti, Gianluca M. Sampietro, Boris Vucelic, C. Janneke van der Woude, Manuel Barreiro-de Acosta, Christian Maaser, Francisco Portela, Stephan R. Vavricka, Fernando Gomollón, on behalf of ECCO
Created: Thursday, 16 March 2017, 4:33 PM by Vesna Babaja

This paper is the second in a series of two publications relating to the European Crohn’s and Colitis Organisation [ECCO] evidence-based consensus on the diagnosis and management of Crohn’s disease [CD] and concerns the surgical management of CD as well as special situations including management of perianal CD and extraintestinal manifestations. Diagnostic approaches and medical management of CD of this ECCO Consensus are covered in the first paper [Gomollon et al. JCC 2016].

ECCO Position Statement on the Use of Biosimilars for Inflammatory Bowel Disease—An Update
Year: 2016
Source: JCC: ECCO Position Statement
Authors: Silvio Danese, Gionata Fiorino, Tim Raine, Marc Ferrante, Karen Kemp, Jaroslaw Kierkus, Peter L. Lakatos, Gerassimos Mantzaris, Janneke van der Woude, Julian Panes, Laurent Peyrin-Biroulet
Created: Thursday, 16 March 2017, 4:39 PM by Vesna Babaja
European Crohn’s and Colitis Organisation Topical Review on IBD in the Elderly
Year: 2016
Source: JCC: ECCO Topical Review
Authors: Andreas Sturm, Christian Maaser, Michael Mendall, Dimitrios Karagiannis, Pantelis Karatzas, Nienke Ipenburg, Shaji Sebastian, Fernando Rizzello, Jimmy Limdi, Konstantinos Katsanos, Carsten Schmidt, Steven Jeuring, Francesco Colombo, Paolo Gionchetti
Created: Thursday, 16 March 2017, 4:49 PM by Vesna Babaja

This ECCO topical review of the European Crohn’s and Colitis Organisation [ECCO] focuses on the epidemiology, pathophysiology, diagnosis, management and outcome of the two most common forms of inflammatory bowel disease, Crohn’s disease and ulcerative colitis, in elderly patients. The objective was to reach expert consensus to provide evidence-based guidance for clinical practice.

European Crohn’s and Colitis Organisation Topical Review on Prediction, Diagnosis and Management of Fibrostenosing Crohn’s Disease
Year: 2016
Source: JCC: ECCO Topical Review
Authors: Florian Rieder, Giovanni Latella, Fernando Magro, Elif S. Yuksel, Peter D. R. Higgins, Antonio Di Sabatino, Jessica R. de Bruyn, Jordi Rimola, Jorge Brito, Dominik Bettenworth, Gert van Assche, Willem Bemelman, Andre d’Hoore, Gianluca Pellino, Axel U. Dignass
Created: Thursday, 16 March 2017, 4:47 PM by Vesna Babaja

This ECCO topical review of the European Crohn’s and Colitis Organisation [ECCO] focused on prediction, diagnosis, and management of fibrostenosing Crohn’s disease [CD]. The objective was to achieve evidence-supported, expert consensus that provides guidance for clinical practice.

How to Apply for and Secure EU Funding for Collaborative IBD Research Projects
Year: 2016
Source: JCC: Viewpoint
Authors: Jack Satsangi, Olivier Kitten, Marcela Chavez, Rahul Kalla, Nadege Prel, Marie-Alice Meuwis, Stephanie Scott, Illaria Bonetti, Nicholas T. Ventham, Edouard Louis
Created: Thursday, 16 March 2017, 5:02 PM by Vesna Babaja

The European Union offers opportunities for high-level of funding of collaborative European research. Calls are regularly published: after the end of the FP7 funding programme the new round of Horizon 2020 calls started in 2015. Several topics are relevant to inflammatory bowel disease (IBD) challenges, including chronic disease management, biomarker discovery and new treatments developments. The aim of this Viewpoint article is to describe the new Horizon 2020 instrument and the project submission procedures, and to highlight these through the description of tips and tricks, taking advantage of four examples of successful projects in the field of IBD: the SADEL, IBD-BIOM, IBD Character and BIOCYCLE projects.

Making a Case for Case Reports: The ECCO-CONFER Viewpoint on Investigating Rare Events in a Medical World Reigned by Group-comparative Statistics
Year: 2017
Source: JCC: Viewpoint
Authors: Konstantinos H. Katsanos, Eugeni Domènech, Jean-François Rahier, Uri Kopylov, Gionata Fiorino, Gerhard Rogler, Edouard Louis, Shomron Ben-Horin
Created: Thursday, 16 March 2017, 5:00 PM by Vesna Babaja
Patient Perspectives on Biosimilars: A Survey by the European Federation of Crohn’s and Ulcerative Colitis Associations
Year: 2016
Source: JCC: Viewpoint
Authors: Laurent Peyrin-Biroulet, Sanna Lönnfors, Xavier Roblin, Silvio Danese, Luisa Avedano
Created: Thursday, 16 March 2017, 5:03 PM by Vesna Babaja

Background and Aim:

The aim of this survey was to find out the patients’ perspectives concerning biosimilars.

Methods:

An online survey consisting of 14 questions was made available between November 2014 and October 2015. Only respondents who had heard of biosimilars were asked to respond the final twelve questions.

Results:

A total of 1181 patients responded. Of these, 38% had heard of biosimilars. The respondents worried about biosimilars’ safety profile [47.0%], efficacy [40.3%], and molecular basis [35.0%]. Only 25.2% of the respondents had no concerns about biosimilars. Just over half [55.9%] of the respondents thought that the lower cost of the biosimilars should not come before their safety and efficacy. Only 12.5% of respondents felt that extrapolation made sense. The survey showed that 39.9% felt that patients should be systematically informed, and 26.7% felt that patient associations should be informed and able to give their opinions. It also revealed that 20.9% of the respondents would be against the idea of interchangeability if the patient was not aware; 65.7% of the respondents would want to know whether they were receiving the reference drug or the biosimilar, and have all necessary information in writing before the drug was administered. Only 31.0% of the respondents would be fully confident about biosimilars, even if they were prescribed and explained by the treating physician.

Conclusions:

Most patients were not familiar with biosimilars, and those who were had doubts and concerns about the biosimilars’ safety and efficacy. The patients wished to be informed and involved in decision-making concerning biosimilars.

Y-ECCO Literature Review: A microbial signature for Crohn's Disease
Year: 2017
Source: ECCO News Issue 1/2017
Authors: Clara Caenepeel
Created: Friday, 21 July 2017, 12:04 PM by ECCO Administrator
Files: 1
Y-ECCO Literature Review: AIM2 contributes to the maintenance of intestinal integrity via Akt and protects against Salmonella mucosal infection
Year: 2016
Source: ECCO News Issue 02/2016
Authors: Wiebe Vanhove
Last Modified: Thursday, 16 March 2017, 4:16 PM by Vesna Babaja
Files: 1
Y-ECCO Literature Review: Cancer recurrence following immune-suppressive therapies in patients with immune-mediated diseases: a systematic review and meta-analysis
Year: 2016
Source: ECCO News Issue 02/2016
Authors: Lieke Spekhorst
Last Modified: Thursday, 16 March 2017, 4:17 PM by Vesna Babaja
Files: 1
Y-ECCO Literature Review: Drug safety and risk of adverse outcomes for pregnant patients with IBD
Year: 2017
Source: ECCO News Issue 1/2017
Authors: Emma Flanagan
Created: Friday, 21 July 2017, 12:05 PM by ECCO Administrator
Files: 1
Y-ECCO Literature Review: Efficacy and safety of MEDI2070, an antibody against interleukin 23, patients with moderate to severe Crohn's Disease: A phase 2a study
Year: 2017
Source: ECCO News 2/2017
Authors: Arne Bokemeyer
Created: Friday, 21 July 2017, 12:07 PM by ECCO Administrator
Files: 1
Y-ECCO Literature Review: Efficicacy of adalimumab in patients with Crohn's Disease and symptomatic small bowel stricture: a multicentre, prospective, observational cohort (CREOLE) study
Year: 2017
Source: ECCO News 2/2017
Authors: Julien Schulberg
Created: Friday, 21 July 2017, 12:08 PM by ECCO Administrator
Files: 1
Y-ECCO Literature Review: Gene-microbiota interactions contribute to the pathogenesis of Inflammatory Bowel Disease
Year: 2016
Source: ECCO News Issue 03/2016
Authors: Floris Imhann
Last Modified: Thursday, 16 March 2017, 4:18 PM by Vesna Babaja
Files: 1
Y-ECCO Literature Review: Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease
Year: 2016
Source: ECCO News Issue 4/2016
Authors: Anna Friederike Cordes
Created: Friday, 21 July 2017, 12:02 PM by ECCO Administrator
Files: 1
Y-ECCO Literature Review: Infliximab reduces endoscopic, but not clinical, recurrence of Crohn’s Disease after ileocolonic resection
Year: 2016
Source: ECCO News Issue 02/2016
Authors: Paula Sousa
Last Modified: Thursday, 16 March 2017, 4:18 PM by Vesna Babaja
Files: 1
Y-ECCO Literature Review: Interleukin 1β mediates intestinal inflammation in mice and patients with interleukin 10 receptor deficiency
Year: 2016
Source: ECCO News Issue 4/2016
Authors: Nurulamin Noor
Created: Friday, 21 July 2017, 11:59 AM by ECCO Administrator
Files: 1
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