DOP23: The role of histology for the prediction of clinical relapse in Crohn’s Disease: A substudy of the STORI cohortECCO'24Year: 2024
Authors: ReenaersDr, C.(1)*;Enea, D.(2);Nachury, M.(3);Laharie, D.(4);Bouhnik, Y.(5);Fumery, M.(6);Gornet, J.M.(7);Amiot, A.(8);Altwegg, R.(9);de Vos , M.(10);Marteau, P.(11);Bourreille, A.(12);Nancey, S.(13);Viennot, S.(14);Louis, E.(15);svrcek, M.(2);
(1)CHU Liège- Sart Tilman, Department of Gastroenterology, Liège, Belgium;(2)Hospital Saint-Antoine, Pathology, Paris, France;(3)CHU Lille, Gastroenterology, Lille, France;(4)CHU Bordeaux, Gastroenterology, Bordeaux, France;(5)Institut des MICI, Gastroenterology, Neuilly-sur-Seine, France;(6)CHU Amiens, Gastroenterology, Amiens, France;(7)Hospital Saint-Louis, Gastroenterology, Paris, France;(8)Kremelin-Bicètre, Gastroenterology, Paris, France;(9)CHU Montpellier, Gatroenterology, Montpellier, France;(10)UZ Ghent, Gastroenterology, Ghent, Belgium;(11)Hospital Saint-Antoine, Gastroenterology, Paris, France;(12)CHU Nantes, Gastroenterology, Nantes, France;(13)CHU Lyon, Gastroenterology, Lyon, France;(14)Clinique de l@E@Alma, Gastroenterology, Paris, France;(15)CHU Liège- Sart Tilman, Gastroenterology, Liège, Belgium;GETAID
DOP24: Multi-omic sequencing reveals distinctive gene expression and DNA methylation alterations as potential predictors of primary sclerosing cholangitis development in treatment-naïve paediatric Ulcerative ColitisECCO'24Year: 2024
Authors: Rodriguez Sosa, A.(1)*;Lawal, O.(1);McDonnell, C.(1);Grant, L.(1);Stephens, I.(1);Genua, F.(1);O@E@Brien, J.(1);Kirwan, G.(1);Kel, A.(2);Dominik, A.(3);Stack, R.(4);Yochum, G.(5);Doherty, G.(6);Hussey, S.(7);Das, S.(1);
(1)Royal College of Surgeons in Ireland, School of Pharmacy and Biomolecular Sciences, Dublin, Ireland;(2)Children@E@s Health Ireland- Crumlin, Department of Pahtology, Crumlin, Ireland;(3)GeneXplain, GmbH, Germany, Germany;(4)st vincent@E@s university hospital and university college Dublin, Center for Colorectal Disease, Dublin, Ireland;(5)Department of Surgery- Division of Colon and Rectal Surgery- Department of Biochemistry & Molecular Biology- The Pennsylvania State University- College of Medicine- PA- USA, Department of Surgery- Division of Colon and Rectal Surgery, Pennsylvania, United States;(6)St. Vincent’s University Hospital and University College Dublin, Center for Colorectal Disease, Dublin, Ireland;(7)DOCHAS Study Children@E@s Health Ireland, Department of Paediatrics UCD, Dublin, Ireland;
DOP25: Antibodies against Neutrophil Extracellular Traps (ANETAs) are associated with more severe disease course in Ulcerative ColitisECCO'24Year: 2024
Authors: Mendieta Escalante, E.A.(1)*;Parada-Venegas, D.(2);Roozendaal, C.(3);Hermoso, M.(2);Bourgonje, A.R.(2);Faber, K.N.(2);Gerard , D.(4);
(1)University Medical Center of Groningen, Gastroenterology and Hepatology, Groningen, The Netherlands;(2)UMCG, Gastroenterology and Hepatology, Groningen, The Netherlands;(3)UMCG, Department of Laboratory Medicine, Groningen, The Netherlands;(4)UMCG, Gastreoenterology and Hepatology, Groningen, The Netherlands;
DOP26: Metagenomic and metabolomic profiles in IBD: understanding microbial and metabolic shifts from a large deeply phenotyped cohortECCO'24Year: 2024
Authors: Marius, B.(1)*;Rolhion, N.(1);Creusot, L.(1);Lefevre, A.(2);Alonso, I.(1);Brot, L.(1);Danne, C.(1);Bourrier, A.(3);Parrot, L.(3);Mélanie, D.(3);Benech, N.(3);Nion-Larmurier, I.(3);Mclellan, P.(3);Landman, C.(3);Beaugerie, L.(3);Seksik, P.(1);Emond, P.(2);Kirchgesner, J.(2);Sokol, H.(1);
(1)Sorbonne Université- Centre de Recherche Saint-Antoine- CRSA, Inserm UMRS-938, Paris, France;(2)University of Tours- Inserm, UMR 1253- iBrain, Tours, France;(3)Saint Antoine Hospital- APHP, Gastroenterology department, Paris, France;
DOP27: Systemic antibody responses against gut microbiota flagellins implicate shared and divergent immune reactivity in Crohn@E@s Disease and chronic fatigue syndromeECCO'24Year: 2024
Authors: Bourgonje, A.R.(1,2)*;Hörstke, N.V.(3);Fehringer, M.(3);Innocenti, G.(3);Vogl, T.(3);
(1)Icahn School of Medicine at Mount Sinai, The Henry D. Janowitz Division of Gastroenterology- Department of Medicine, New York, United States;(2)University Medical Center Groningen, Gastroenterology and Hepatology, Groningen, The Netherlands;(3)Medical University of Vienna, Center for Cancer Research, Vienna, Austria;
DOP28: Yield of surveillance colonoscopy in patients with Primary Sclerosing CholangitisECCO'24Year: 2024
Authors: Van De Pol, N.(1)*;Mol, B.(2);de Jong, M.J.(1);Weersma, R.K.(3);Inderson, A.(4);Slooter, F.C.(2);Gibbes, L.A.(2);van der Meer, A.J.(1);Derikx, L.A.A.P.(1);Ponsioen, C.Y.(2);de Vries, A.C.(1);
(1)Erasmus University Medical Center, Gastroenterology and hepatology, Rotterdam, The Netherlands;(2)Amsterdam University Medical Center, Gastroenterology and hepatology, Amsterdam, The Netherlands;(3)University Medical Center Groningen, Gastroenterology and hepatology, Groningen, The Netherlands;(4)Leiden University Medical Center, Gastroenterology and hepatology, Leiden, The Netherlands;on behalf of the EpiPSC2 Study Group
DOP29: Capsule endoscopy-guided proactive treatment versus standard treatment of patients with quiescent Crohn’s Disease: The CURE-CD randomized controlled trialECCO'24Year: 2024
Authors: Ben-Horin, S.(1)*;Lahat, A.(2);Ungar, B.(2);Ukashi, O.(2);Yablecovitch, D.(2);Amitai, M.M.(3);Haberman, Y.(4);Selinger, L.(2);Talan-Asher, A.(2);Kriger-Sharabi, O.(5);Naftali, T.(6);Ron, Y.(7);Yanai, H.(8);Dotan, I.(8);Kopylov, U.(2);Eliakim, R.(2);
(1)Tel-HaShomer Sheba Medical Center, Department of Gastroenterology, Ramat Gan, Israel;(2)Sheba Medical Center- Tel-Avivi University, Gastroenterology, Ramat Gan, Israel;(3)Sheba Medical Center- Tel-Avivi University, Radiology, Ramat Gan, Israel;(4)Sheba Medical Center- Tel-Avivi University, Gastroenterology, Ramat Ganisra, Israel;(5)Assuta Medical Center, Gastroenterology, Ashdod, Israel;(6)Meir Medical Center, Gastroenterology, Kfar Saba, Israel;(7)Tel Aviv Medical Center, Gastroenterology, Tel-Aviv, Israel;(8)Rabin Medical Center, Gastroenterology, Petah-Tiqwa, Israel;The Israeli IBD Research Nucleus (IIRN)
DOP30: Cross-ethnic microbiome analyses identify shared and specific signals for Northern Indian IBD patientsECCO'24Year: 2024
Authors: Singh, A.(1);Gacesa, R.(2)*;Juyal, G.(3);Joshi, M.(4);Midah, V.(5);Thelma, B.K.(6);Weersma, R.K.(2);Sood, A.(1);
(1)Dayanand Medical College & Hospital, Department of Gastroenterology, Ludhiana, India;(2)University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, The Netherlands;(3)School of Engineering and Applied Sciences- Bennett University, Department of Biotechnology, Greater Noida, India;(4)Jamia Millia Islamia, Multidisciplinary Centre for Advance Research and Studies MCARS, New Delhi, India;(5)Dayanand Medical College & Hospital, Department of Internal Medicine, Ludhiana, India;(6)University of Delhi South Campus, Department of Genetics, New Delhi, India;
DOP31: Gene correlation network analyses reveal transcript modules and pathogenic mechanisms associated with resistance and response to ustekinumab therapy in Ulcerative ColitisECCO'24Year: 2024
Authors: Saifuddin, A.(1)*;Cozzetto, D.(1);Olbei, M.(1);Hart, A.(2);Korcsmaros, T.(1);Powell, N.(1);
(1)Imperial College London, Department of Metabolism- Digestion and Reproduction, London, United Kingdom;(2)St Mark@E@s Academic Institute, Inflammatory Bowel Disease, London, United Kingdom;
DOP32: CD226+TIGITneg expression identifies pathogenic inflammatory CD4+ memory T cells in severe Crohn’s Disease patients, opening up opportunities for patient-tailored treatment strategies.ECCO'24Year: 2024
Authors: Barendregt, D.(1)*;Heredia, M.(1);Tindemans, I.(1);Klomberg, R.C.W.(2);Calado, B.(1);Hulleman-van Haaften, D.H.(1);Bastiaan, T.(1);van Berkel, L.A.(1);Escher, J.C.(2);de Ridder, L.(2);Samsom, J.N.(1);
(1)Erasmus University Medical Center-Sophia Children’s Hospital, Laboratory of Pediatrics, Rotterdam, The Netherlands;(2)Erasmus University Medical Center-Sophia Children’s Hospital, Department of Pediatric Gastroenterology, Rotterdam, The Netherlands;PIBD-SETQuality Consortium
DOP33: Distinct perturbances in metabolic pathways associate with disease progression in patients with Inflammatory Bowel DiseaseECCO'24Year: 2024
Authors: Bourgonje, A.R.(1)*;Ibing, S.(2,3);Argmann, C.(4);Sands, B.E.(1);Dubinsky, M.(1);Jacobsen, H.A.(5);Suarez-Farinas, M.(6);Mehandru, S.(1);Colombel, J.F.(1);Ungaro, R.C.(1);
(1)Icahn School of Medicine at Mount Sinai, The Henry D. Janowitz Division of Gastroenterology- Department of Medicine, New York, United States;(2)Icahn School of Medicine at Mount Sinai, Hasso Plattner Institute for Digital Health at Mount Sinai, New York, United States;(3)University of Potsdam, Hasso Plattner Institute- Digital Engineering Faculty, Potsdam, Germany;(4)Icahn School of Medicine at Mount Sinai, Department of Genetics and Genomic Sciences, New York, United States;(5)Aalborg University, Center for Molecular Prediction of Inflammatory Bowel Disease- PREDICT- Department of Clinical Medicine- The Faculty of Medicine, Aalborg, Denmark;(6)Icahn School of Medicine at Mount Sinai, Center of Biostatistics, New York, United States;
DOP34: Deciphering immune-epithelial interactions in health and in Inflammatory Bowel DiseaseECCO'24Year: 2024
Authors: Jowett, G.M.(1);Read, E.(1);Pena-Cearra, A.(1);Coman, D.(1); Coales, I.(1);Kromann, E.(1);Ilangovan, J.(1);Roberts, L.(2);Gentleman, E.(3);Lord, G.M.(4);Neves, J.F.(1)*;
(1)King@E@s College London, Centre for Host-Microbiome Interactions, London, United Kingdom;(2)Manchester University, Faculty of Biology- Medicine and Health, Manchester, United Kingdom;(3)King@E@s College London, Craniofacial & Regenerative Biology, London, United Kingdom;(4)University of Manchester, Faculty of Biology- Medicine and Health, Manchester, United Kingdom;
DOP35: Spatial transcriptomics reveals cellular niches associated with histological inflammation in postoperative Crohn’s DiseaseECCO'24Year: 2024
Authors: Battat, R.(1,2)*;Sangiorgi, B.(3);Linggi, B.(3);Gui, S.(4,5);Torti, D.(3);Smith, M.I.(3);Mehandru, S.(6);Longman, R.(2);Lukin, D.J.(2);Scherl, E.J.(2);Qin, L.(7);Ma, C.(3,8,9);Teft, W.(3);Vande Casteele, N.(4,10);
(1)University of Montreal Hospital Center, Division of Gastroenterology and Hepatology, Montreal, Canada;(2)Weill Cornell Medicine, Jill Roberts Center for IBD- Division of Gastroenterology and Hepatology, New York, United States;(3)Alimentiv Inc., Medical R&D, London, Canada;(4)AcelaBio, Department of Pathology, San Diego, United States;(5)University of Washington, Department of Laboratory Medicine and Pathology, Seattle, United States;(6)Icahn School of Medicine at Mount Sinai, Division of Gastroenterology- Department of Medicine, New York, United States;(7)Weill Cornell Medical College of Cornell University, Division of Anatomic Pathology- New York-Presbyterian Hospital- Department of Pathology and Laboratory Medicine, New York, United States;(8)University of Calgary, Division of Gastroenterology & Hepatology- Cumming School of Medicine, Calgary, Canada;(9)University of Calgary, Department of Community Health Sciences- Cumming School of Medicine, Calgary, Canada;(10)University of California San Diego, Department of Medicine, La Jolla, United States;
DOP37: Noninvasive assessment of gut function using transcriptional recording sentinel cellsECCO'24Year: 2024
Authors: Zimmermann, J.(1,2)*;Macpherson, A.(1,2);
(1)Inselspital- University Hospital, Department of Visceral Surgery and Medicine, Bern, Switzerland;(2)University of Bern, Department for BioMedical Research, Bern, Switzerland;
DOP38: A rare KRT17+ population emerges from the epithelium in the inflamed intestinal mucosa of patients with Ulcerative ColitisECCO'24Year: 2024
Authors: Dotti, I.(1,2)*;Melón-Ardanaz , E.(1,2);Sanzo, Á.(1,2);Gudiño, V.(1,2);Corraliza, A.M.(1,2);Teubel, I.(1,2);Esteller, M.(1,2);Ricart, E.(1,2);Salas, A.(1,2);
(1)Fundació de Recerca Clínic Barcelona-Institut d@E@Investigacions Biomèdiques August Pi i Sunyer FRCB-IDIBAPS, Inflammatory Bowel Disease Unit, Barcelona, Spain;(2)Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Ciberehd, Madrid, Spain;
DOP39: Constructing butyrate-producing yeast as a cell-dependent treatment option for Inflammatory Bowel DiseaseECCO'24Year: 2024
Authors: Wu, J.(1)*;Kang, G.(1);Wang, L.(1);Gao, M.(1);Meng, S.(1);Cao, X.(2);Li, B.(1);Huang, H.(1);
(1)Tianjin University, Department of Biochemical Engineering, Tianjin, China;(2)Tianjin Medical University General Hospital, Department of Gastroenterology and Hepatology, Tianjin, China;
DOP40: Inflammatory Bowel Disease single cell atlas construction to enable cell type-specific target identificationECCO'24Year: 2024
Authors: De Baets, G.(1);D@E@Rozario, J.(2);Gehrman, U.(3);Mattsson, J.(3);Castiblanco, D.(2);Kaymak, I.(2);Moldoveanu, A.L.(2);Giorgio, C.(2);Prandi, F.(2);Jawale, C.(4);Honsa, P.(5);Ruppova, K.(5);Valny, M.(5);Macuchova, E.(5);Elizaveta Freinkman, E.(5);Sponarova, J.(5);Platt, A.(1);Ort, T.(4);Corridoni, D.(2)*;
(1)AstraZeneca- BioPharmaceuticals R&D- Research and Early Development, Early Respiratory and Immunology- Translational Science and Experimental Medicine, Cambridge, United Kingdom;(2)AstraZeneca- BioPharmaceuticals R&D- Research and Early Development, Early Respiratory and Immunology- Bioscience Immunology, Cambridge, United Kingdom;(3)AstraZeneca- BioPharmaceuticals R&D- Research and Early Development, Early Respiratory and Immunology- Translational Science and Experimental Medicine, Gothenburg, Sweden;(4)AstraZeneca- BioPharmaceuticals R&D- Research and Early Development, Early Respiratory and Immunology- Bioscience Immunology, Gaithersburg, United States;(5)Immunai Inc., Immunai, New York, United States;
DOP41: Mucosal single-cell profiling of Crohn@E@s-like disease of the pouch reveal unique pathogenesis and therapeutic targetsECCO'24Year: 2024
Authors: Cao, S.(1)*;Deepak, P.(2);Colonna, M.(3);
(1)Washington University in St. Louis, gastroenterology, St. Louis, United States;(2)Washington University, Gastroenterology, St. Louis, United States;(3)Washington University, Pathology and Immunology, St. Louis, United States;
DOP43: Histologic improvement, attenuation of inflammation and microbiome modulation by engineered high acetate producing Saccharomyces boulardii in DSS-induced colitisECCO'24Year: 2024
Authors: Deleu, S.(1)*;Trindade de Carvalho , B.(2);Jacobs, I.(3);Vazquez Castellanos, J.(4,5);Verstockt, S.(1);Verstockt, B.(6,7);Arnauts, K.(1);Deprez, L.(1);Vissers, E.(1);Lenfant, M.(1);De Hertogh , G.(8);Huys, G.(4,5);Thevelein, J.(2);Raes, J.(4,5);Vermeire, S.(6,7);
(1)KU Leuven, Department of Chronic Diseases and Metabolism CHROMETA, Leuven, Belgium;(2)Bio-Incubator BIO4, Novelyeast bv, Leuven, Belgium;(3)KU Leuven, Department of Microbiology- Immunology and Transplantation, Leuven, Belgium;(4)KU Leuven, Department of Microbiology and Immunology, Leuven, Belgium;(5)VIB, Center for microbiology, Leuven, Belgium;(6)KU Leuven, Department of Chronic Diseases and Metabolism CHROMETA, Leuven, Belgium;(7)University Hospital Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium;(8)University Hospital Leuven, Laboratory of Morphology and Molecular Pathology, Leuven, Belgium;
DOP44: Melatonin Ameliorates Colitis In DSS-fed Mice Via The SIRT1 PathwayECCO'24Year: 2024
Authors: Lin, B.(1,2);Mao, Q.(1,2);Zhang, W.(1,2); Zhang, Y.(1,2);Cao, Q.(1,2);Xu, M.(1,2); Liu, J.(1,2)*;
(1)Sir Run Run Shaw Hospital- College of Medicine Zhejiang University, Gastroenterology, Hangzhou, China;(2)Sir Run Run Shaw Hospital- College of Medicine Zhejiang University, Inflammatory bowel disease center, Hangzhou, China;
