P1272: Spatio-temporal distribution of IBD incidence at a territorial level in northern France using the EPIMAD registry (2000-2017): analysis of environmental determinants suggests influence of agricultural practices.ECCO'25Year: 2025
Authors: Paumelle, M.(1)*;Occelli, F.(1);Sarter, H.(2);Fumery, M.(3);Savoye, G.(4);Ley, D.(5);Lanier, C.(1);Wakim, L.M.(1);Deram, A.(1);Genin, M.(6);
(1)Univ. Lille- IMT Lille Douai- Univ. Artois- JUNIA, ULR 4515- LGCgE- Laboratoire de Génie Civil et géo-Environnement, Lille, France;(2)CHU Lille- Public Health- Epidemiology and Economic Health Unit- EPIMAD Registry- Maison Régionale de la Recherche Clinique, & Univ. Lille- Inserm- CHU Lille- U1286 - INFINITE - Institute for Translational Research in Inflammation, Lille, France;(3)Gastroenterology Unit- Amiens University Hospital, and Peritox- UMRI01- Université de Picardie Jules Verne, Amiens, France;(4)Univ Rouen Normandie, INSERM- ADEN UMR1073- “Nutrition- Inflammation and Microbiota-gut-brain axis”- CHU Rouen- Department of Gastroenterology, Rouen, France;(5)Univ. Lille- Inserm- CHU Lille- U1286 - INFINITE - Institute for Translational Research in Inflammation, & CHU Lille- Division of Gastroenterology- Hepatology- and Nutrition- Department of Paediatrics- Lille F-59000- France, Lille, France;(6)Univ Lille- CHU Lille, ULR 2694 – METRICS : Évaluation des technologies de santé et des pratiques médicales, Lille, France;
P1273: High Crohn's Disease incidence associated with multiple heavy metal contamination in agricultural soils: findings from the CROPS project in Northern FranceECCO'25Year: 2025
Authors: Wakim, L.M.(1)*;Occelli, F.(1);Sarter, H.(2);Fumery, M.(3);Savoye, G.(4);Lanier, C.(1);Ley, D.(5);Paumelle, M.(1);Genin, M.(6);Deram, A.(1);
(1)Univ. Lille- IMT Lille Douai- Univ. Artois- JUNIA, ULR 4515- LGCgE- Laboratoire de Génie Civil et géo-Environnement, F-59000- Lille, France;(2)CHU Lille- Public Health- Epidemiology and Economic Health Unit- EPIMAD Registry- Maison Régionale de la Recherche Clinique, Univ. Lille- Inserm- CHU Lille- U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000- Lille, France;(3)Gastroenterology Unit- Amiens University Hospital and Peritox, UMRI01- Université de Picardie Jules Verne, F-80000- Amiens, France;(4)Univ. Rouen Normandie- INSERM- ADEN UMR1073 "Nutrition- Inflammation and Microbiota-gut-brain axis"- CHU Rouen, Department of Gastroenterology, F-76000- Rouen, France;(5)Univ. Lille- Inserm- CHU Lille- U1286 - INFINITE - Institute for Translational Research in Inflammation, CHU Lille- Division of Gastroenterology- Hepatology- and Nutrition- Department of Pediatrics, F-59000- Lille, France;(6)Univ. Lille- CHU Lille, ULR2694 - METRICS : Evaluation des technologies de santé et des pratiques médicales, F-59000- Lille, France;
P1274: The Astur-Frailty-IBD Study: Assessment of Frailty in elderly IBD patients and comparison of four frailty scores.ECCO'25Year: 2025
Authors: Carballo-Folgoso, L.(1)*;Duque Alcorta , J.M.(2);Varela, P.(3);De Francisco García, R.(1,4);Armesto González , E.(2);Mancebo Mata , A.(3);Pérez-Martínez , I.(1,4);Rodríguez López , P.(2);De Jorge Turrión , M.A.(3);Castaño-García , A.(1);García-Pérez , C.(5);Martínez Martín , G.(5);Fernández-González, E.(1);Chiminazzo , V.(6);Díaz-Simal , A.(1);Suarez, A.(1,4);Riestra , S.(1,4);
(1)Hospital Universitario Central de Asturias, Gastroenterology Department, Oviedo, Spain;(2)Hospital Universitario San Agustín, Gastroenterology Department, Avilés, Spain;(3)Hospital Universitario de Cabueñes, Gastroenterology Department, Gijón, Spain;(4)Instituto de Investigación Sanitaria del Principado de Asturias DIMISA-ISPA, Diet- Microbiota and Health Group, Oviedo, Spain;(5)Fundación para la Investigación y la Innovación Biosanitaria del Principado de Asturias FINBA, Instituto de Investigación Sanitaria del Principado de Asturias ISPA, Oviedo, Spain;(6)Instituto de Investigación Sanitaria del Principado de Asturias ISPA, Statistics Unit, Oviedo, Spain;
P1275: Understanding the burden of severe ulcerative colitis: outcomes and treatment use in a large U.S. cohortECCO'25Year: 2025
Authors: Raine, T.(1)*;Lewis, J.(2);Chen, Y.(3);Parkes, G.(4);Huisingh, C.(5);Wegrzyn, L.(5);
(1)Cambridge University Hospitals, Department of Gastroenterology, London, United Kingdom;(2)Center for Clinical Epidemiology and Biostatistics- University of Pennsylvania, Division of Gastroenterology and Hepatology, Philadelphia, United States;(3)AbbVie, Epidemiology, Mettawa, United States;(4)Barts and the London School of Medicine and Dentistry- London- UK- Royal London Hospital, Department of Gastroenterology, Cambridge, United Kingdom;(5)AbbVie Inc., Epidemiology, Mettawa, United States;
P1276: Persistent Insomnia Ignites the Flames of Crohn's Disease by Elevating Systemic InflammationECCO'25Year: 2025
Authors: Cao, X.(1,2)*;Zhao, J.(2);Zhang, M.(2);Lou, S.(3);Cao, Q.(1);
(1)Sir Run Run Shaw Hospital- College of Medicine Zhejiang University, Department of Gastroenterology, Hangzhou, China;(2)The Second Affiliated Hospital and School of Public Health- Zhejiang University School of Medicine, Department of Big Data in Health Science, Hangzhou, China;(3)Sir Run Run Shaw Hospital- College of Medicine Zhejiang University, Department of General Surgery, Hangzhou, China;
P1277: Cost-effectiveness of BOOST online intervention for supported self-management of pain, fatigue and bowel incontinence in Inflammatory Bowel DiseaseECCO'25Year: 2025
Authors: Roukas, C.(1)*;Miller, L.(2);Cléirigh Büttner, F.(3);Hamborg, T.(3);Norton, C.(4);Hart, A.(5);Mihaylova, B.(1);
(1)Queen Mary University of London, Health Economics and Policy Research Unit, London, United Kingdom;(2)Queen Mary University of London, Unit for Social and Community Psychiatry, London, United Kingdom;(3)Queen Mary University of London, Pragmatic Clinical Trials Unit, London, United Kingdom;(4)King's College London, Midwifery and Palliative Care, London, United Kingdom;(5)St Mark's Hospital, IBD Unit, London, United Kingdom;
1. Roukas, C., Miller, L., Cléirigh Büttner, F., Hamborg, T., Stagg, I., Hart, A., ... & Mihaylova, B. (2024). Impact of pain, fatigue and bowel incontinence on the quality of life of people living with inflammatory bowel disease: A UK cross‐sectional survey. United European gastroenterology journal.
2. Norton, C., Syred, J., Kerry, S., Artom, M., Sweeney, L., Hart, A., ... & Moss-Morris, R. (2021). Supported online self-management versus care as usual for symptoms of fatigue, pain and urgency/incontinence in adults with inflammatory bowel disease (IBD-BOOST): study protocol for a randomised controlled trial. Trials, 22, 1-18.
3. Norton, C., Moss Morris, R., Hart, A., Cleirigh Buettner, F., Hamborg, T., Miller, L., ... & Wileman, V. (2024). P651 A randomised controlled trial of IBD-BOOST, a digital cognitive behavioural self-management programme for fatigue, and/or pain, and/or faecal incontinence in inflammatory bowel disease. Journal of Crohn's and Colitis, 18(Supplement_1), i1240-i1242.
P1278: The use of pain and sedative medications among individuals with a diagnosis of Inflammatory Bowel Disease.ECCO'25Year: 2025
Authors: Baillie, S.(1)*;Jayasooriya, N.(2);Blackwell, J.(3);Bottle, A.(4);Petersen, I.(5);Saxena, S.(4);Pollok, R.(6);
(1)St George's University Hospitals NHS Foundation Trust, Department of Gastroenterology, London, United Kingdom;(2)Homerton Healthcare NHS Foundation Trust, Department of Gastroenterology, London, United Kingdom;(3)Western General Hospital, Department of Gastroenterology, Edinburgh, United Kingdom;(4)Imperial College London, School of Public Health, London, United Kingdom;(5)University College London, Department of Primary Care and Population Health, London, United Kingdom;(6)St George’s University Hospitals NHS Foundation Trust, Department of Gastroenterology, London, United Kingdom; POP-IBD
- J Crohns Colitis. 2023;17(Supplement_1):i130-i132. doi:10.1093/ecco-jcc/jjac190.0099
2. Sir Liam Donaldson. Chief Medical Officer’s Update. Department of Health; 2004:4. Accessed August 21, 2024. https://webarchive.nationalarchives.gov.uk/ukgwa/20120503095605/http://www.dh.gov.uk/en/Publicationsandstatistics/Lettersandcirculars/CMOupdate/DH_4070172
3. Chronic Pain (Primary and Secondary) in over Sixteens: Assessment of All Chronic Pain and Management of Chronic Primary Pain. National Institute for Health and Care Excellence; 2021. https://www.nice.org.uk/guidance/ng193
4. Faculty of Pain Medicine. Surgery and Opioids: Best Practice Guidelines 2021. Published online March 2021.
P1279: Associations of accelerometer-measured moderate-to-vigorous physical activity with bowel resection risk and mortality among individuals with inflammatory bowel disease: a prospective cohort studyECCO'25Year: 2025
Authors: He, Z.(1)*;Sun, Y.(2);Huang, H.(3);Liu, Y.(4);Dan, L.(5);Ruan, X.(3);Li, Z.(1);Wang, X.(3);Chen, J.(3);Bai, Y.(1);
(1)Changhai Hospital- Naval Medical University, Department of Gastroenterology, Shanghai, China;(2)The Second Affiliated Hospital of Zhejiang University School of Medicine, Department of Gastroenterology, Hangzhou, China;(3)The Third Xiangya Hospital- Central South University, Department of Gastroenterology, Changsha, China;(4)Naval Medical University, College of Basic Medicine Sciences, Shanghai, China;(5)Ruijin Hospital- School of Medicine- Shanghai Jiao Tong University, Department of Gastroenterology, Shanghai, China;
P1280: Gender identity and inflammatory bowel disease: estimates of prevalence across EuropeECCO'25Year: 2025
Authors: Colwill , M.(1,2)*;Pollok , R.(2);Poullis , A.(2);
(1)St George's University Hospitals NHS Foundation Trust, Gastroenterology, London, United Kingdom;(2)City St George's- University of London, Gastroenterology, London, United Kingdom;
References
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P1281: Active perianal fistulising Crohn’s Disease is associated with a higher burden of psychological distress, depression, anxiety, stress and opioid useECCO'25Year: 2025
Authors: Gu, B.(1,2)*;Su, W.K.(1,3);Nano, D.(1);Wilson, W.(4);Iliescu, S.(1);Lynch, K.(5,6);Andrews, J.M.(3,5,6);Connor, S.J.(1,2,3);Ghaly, S.(7,8);
(1)Liverpool Hospital, Department of Gastroenterology and Hepatology, Sydney, Australia;(2)University of New South Wales, South Western Sydney Clinical School, Sydney, Australia;(3)Crohn's Colitis Cure, Crohn's Colitis Cure, Sydney, Australia;(4)Lyell McEwin Hospital, Department of Anaesthesiology, Adelaide, Australia;(5)Royal Adelaide Hospital, Department of Gastroenterology and Hepatology, Adelaide, Australia;(6)University of Adelaide, Faculty of Health Sciences, Adelaide, Australia;(7)St Vincent's Public Hospital, Department of Gastroenterology and Hepatology, Sydney, Australia;(8)University of New South Wales, St Vincent's Clinical School, Sydney, Australia;
P1282: Type 2 diabetes mellitus in IBD patients: a case control study through a long follow up periodECCO'25Year: 2025
Authors: Zaccardi, B.(1)*;Ribaldone, D.G.(2);
(1)Università degli studi di Torino, Gastroenterologia, Torino, Italy;(2)università degli studi di Torino, Gastroenterology, Torino, Italy;
Yarur AJ, Strobel SG, Deshpande AR, Abreu MT. Predictors of aggressive inflammatory bowel disease. Gastroenterol Hepatol (NY). 2011;7(10):652-659.
CDC. National Diabetes Statistics Report. Diabetes. Published June 6, 2024. Accessed June 12, 2024.https://www.cdc.gov/diabetes/php/data-research/index.html
Gomollón F, Dignass A, Annese V, et al. 3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn's Disease 2016: Part 1: Diagnosis and Medical Management. Journal of Crohn's and Colitis. 2017;11(1):3-25. doi:10.1093/ecco-jcc/jjw168
P1283: Adherence to Infectious Disease Assessment at Baseline in Patients with Inflammatory Bowel Disease: A Retrospective Study from a Medical CenterECCO'25Year: 2025
Authors: Huang, C.W.(1,2)*;Yen, H.H.(1,3);Chen, Y.Y.(1);
(1)Changhua Christian Hospital, Division of Gastroenterology, Changhua, Taiwan;(2)National Taiwan University, Graduate Institute of Clinical Medicine, Taipei, Taiwan;(3)National Chung Hsing University, Post-Baccalaureate Medicine, Taichung, Taiwan;
1. Kucharzik T, Ellul P, Greuter T, Rahier JF, Verstockt B, Abreu C, Albuquerque A, Allocca M, Esteve M, Farraye FA, Gordon H, Karmiris K, Kopylov U, Kirchgesner J, MacMahon E, Magro F, Maaser C, de Ridder L, Taxonera C, Toruner M, Tremblay L, Scharl M, Viget N, Zabana Y, Vavricka S. ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease. J Crohns Colitis. 2021 Jun 22;15(6):879-913.
2. Vitello A, Maida M, Shahini E, Macaluso FS, Orlando A, Grova M, Ramai D, Serviddio G, Facciorusso A. Current Approaches for Monitoring of Patients with Inflammatory Bowel Diseases: A Narrative Review. J Clin Med. 2024 Feb 9;13(4):1008.
3.Irving PM, de Lusignan S, Tang D, et alRisk of common infections in people with inflammatory bowel disease in primary care: a population-based cohort studyBMJ Open Gastroenterology 2021;8:e000573.
P1284: Prevalence of immune-mediated extraintestinal manifestations in paediatric Inflammatory Bowel Disease: a systematic review and meta-analysisECCO'25Year: 2025
Authors: Colman, R.J.(1);Vuyyuru, S.K.(2,3);Solitano , V.(2,4);MacDonald, J.K.(3);Ricciuto , A.(5);Berard, R.(6);Mohammed, J.(7);Ma, C.(3,8,9);Jairath, V.(2,3,10);Crowley, E.(3,11)*;
(1)Stanford University School of Medicine, Department of Pediatrics- Division of Pediatric Gastroenterology- Hepatology and Nutrition, Stanford, United States;(2)Western University, Department of Medicine- Division of Gastroenterology, London, Canada;(3)Alimentiv Inc., Medical R&D, London, Canada;(4)IRCCS Ospedale San Raffaele- Università Vita-Salute San Raffaele, Division of Gastroenterology and Gastrointestinal Endoscopy, Milan, Italy;(5)The Hospital for Sick Children, Division of Gastroenterology- Hepatology and Nutrition, Toronto, Canada;(6)Western University- Schulich School of Medicine and Dentistry, Department of Paediatrics- Division of Paediatric Rheumatology, London, Canada;(7)Children's Hospital- London Health Sciences Centre- Western University, Department of Paediatrics, London, Canada;(8)University of Calgary, Department of Community Health Sciences, Calgary, Canada;(9)University of Calgary, Department of Medicine- Division of Gastroenterology & Hepatology, Calgary, Canada;(10)Western University, Department of Epidemiology and Biostatistics, London, Canada;(11)Western University, Department of Paediatric- Division of Paediatric Gastroenterology- Hepatology and Nutrition, London, Canada;
P1285: Incidence of venous thromboembolism in Asian patients with inflammatory bowel disease: a systematic review and meta-analysisECCO'25Year: 2025
Authors: Song, J.H.(1)*;Shim, S.R.(2);Kim, D.S.(3);Koo, H.S.(3);Huh, K.C.(3);
(1)Konkuk University Medical center, Internal medicine, Seoul, Korea- Republic Of;(2)Konyang University, Biomedical Informatics, Daejeon, Korea- Republic Of;(3)Konyang University, Internal Medicine, Daejeon, Korea- Republic Of;
P1286: Prevalence, concordance and course of disease in first-degree relatives with Inflammatory Bowel DiseaseECCO'25Year: 2025
Authors: MantzarisMD- PhD- AGAF- FEBG- MACG, G.(1)*;
(1)Solo Practice, White Cross Hospital- The Athens Clinic, Athens, Greece;
P1287: Comparative Analysis of IBD Management: Hospital Versus Community-based CareECCO'25Year: 2025
Authors: Israel, A.(1);Sharif, K.(2);Lahat, A.(2)*;
(1)Leumit Health Services, Leumit Research Institute and Department of Family Medicine, Tel Aviv-Yafo, Israel;(2)Chaim Sheba Medical Center, Gastroenterology, Ramat Gan, Israel;
P1288: The Association of Long-term Night Shift Work and Related Circulating Proteins with Inflammatory Bowel Disease: A Prospective Cohort and Multi-omics StudyECCO'25Year: 2025
Authors: Zhao, J.(1)*;Xue, E.(1);Yu, G.(1);Ye, J.(1);Li, X.(1);
(1)Zhejiang University, Medical School, Hangzhou, China;
P1289: Sleep Quality and Associated Factors in Patients with Inflammatory Bowel Disease: A Cross-Sectional StudyECCO'25Year: 2025
Authors: Asgharnezhad, M.(1);Maroufizadeh, S.(2);Isanazar, A.(3);Hedayatzadeh, Z.(1);Joukar, F.(1);Mansour Ghanaei, F.(4)*;
(1)Guilan University of Medical Sciences, Gastrointestinal and Liver Diseases Research Center, Rasht, Iran- Islamic Republic Of;(2)Guilan University of Medical Sciences, Department of Biostatistics and Epidemiology- School of Health, Rasht, Iran- Islamic Republic Of;(3)Guilan University of Medical Sciences, Kavosh Cognitive Behavior Sciences and Addiction Research Center- School of Medicine, Rasht, Iran- Islamic Republic Of;(4)Guilan University of Medical Science, Department of Gastroenterology, Rasht, Iran- Islamic Republic Of;
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P1290: Gene set polygenic risk scores identifies genetic subgroups in inflammatory bowel disease patientsECCO'25Year: 2025
Authors: Jans, D.(1)*;Smeulders, E.(1);Veyt, N.(1);Ferrante, M.(2,3);Verstockt, B.(2,3);Sabino, J.(2,3);Vermeire, S.(2,3);Cleynen, I.(1);
(1)KU Leuven, Department of Human Genetics, Leuven, Belgium;(2)University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium;(3)KU Leuven, Department of Chronic Disease, Leuven, Belgium;
1. de Lange KM, Moutsianas L, Lee JC, et al. Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. Nature genetics. 2017;49(2):256-261. doi:10.1038/NG.3760
2. Cleynen I, Boucher G, Jostins L, et al. Inherited determinants of Crohn’s disease and ulcerative colitis phenotypes: a genetic association study. Lancet (London, England). 2016;387(10014):156-167. doi:10.1016/S0140-6736(15)00465-1
P1291: Transcriptional heterogeneity of granzyme K CD8 T Cells in Crohn's Disease: Implications for tissue inflammationECCO'25Year: 2025
Authors: Lee, Y.(1);Baek, J.(1);Kim, Y.(1);Hwang, S.W.(2);Lee, J.L.(3);Park, S.H.(2);Kim, J.(4);Yang, S.K.(2);Han, B.(5);Kweon, M.N.(6);Song, K.(1);Yoon, Y.S.(3);Ye, B.D.(2);Lee, H.S.(1)*;
(1)University of Ulsan College of Medicine- Asan Medical Center, Department of Biochemistry and Molecular Biology, Seoul, Korea- Republic Of;(2)University of Ulsan College of Medicine- Asan Medical Center, Department of Gastroenterology- Inflammatory Bowel Disease Center, Seoul, Korea- Republic Of;(3)University of Ulsan College of Medicine- Asan Medical Center, Division of Colon and Rectal Surgery- Department of Surgery- Inflammatory Bowel Disease Center, Seoul, Korea- Republic Of;(4)University of Ulsan College of Medicine- Asan Medical Center, Department of Pathology, Seoul, Korea- Republic Of;(5)Seoul National University College of Medicine, Department of Biomedical Sciences, Seoul, Korea- Republic Of;(6)University of Ulsan College of Medicine- Asan Medical Center, Mucosal Immunology Laboratory, Seoul, Korea- Republic Of;