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P007: Oral tyrosine kinase 2 inhibitor ameliorates T cell transfer colitisECCO '17 Barcelona
Year: 2017
Authors:

De Vries L.*1,2, Wildenberg M.1,2, van Hamersveld P.2, Welting O.2, Verseijden C.2, D'Haens G.1, De Jonge W.2

1Academic Medical Center, Gastroenterology & Hepatology, Amsterdam, Netherlands 2Academic Medical Center, Tytgat Institute for Liver and Intestinal Research, Amsterdam, Netherlands

P008: Common and different inflammatory features in inflammatory bowel disease and colon cancerECCO '17 Barcelona
Year: 2017
Authors:

Lo Presti E.*1, Di Mitri R.2, Dieli F.1, Mocciaro F.2, Cilluffo M.G.3, Pecoraro G.M.4, Russo G.2, Meraviglia S.1

1University of Palermo, Department of Biopathology and Medical Biotechnologies (DIBIMED), University of Palermo; (CLADIBIOR), Palermo, Italy 2ARNAS Civico-Di Cristina-Benfratelli Hospital, Gastroenterology and Endoscopy Unit, Palermo, Italy 3A.O.U. Policlinico “G. Giaccone”, Gastroenterology and Hepatology Unit, Palermo, Italy 4Cattinara Hospital, Department of Gastroenterolgy, Trieste, Italy

P009: Autophagy stimulation reduces mucosal NF-κB protein levels and ameliorates murine colitisECCO '17 Barcelona
Year: 2017
Authors:

Macias Ceja D.C.*1,2, Cosín-Roger J.3, Ortiz-Masià D.2, Salvador P.2, Gisbert-Ferrándiz L.2, Hernandez C.1,3, Esplugues J.V.1,2,3, Calatayud S.2,3, Barrachina M.D.2,3

1Fisabio Hospital Peset, Valencia, Spain 2University of Valencia, Valencia, Spain 3CIBERehd, Valencia, Spain

P010: Effects of cigarette smoke on the DSS-induced colitis model in C57Bl/6 miceECCO '17 Barcelona
Year: 2017
Authors:

Phillips B.1, Lo Sasso G.*2, Talikka M.2, Veljkovic E.1, Martin F.2, Elamin A.2, Guedj E.2, Ivanov N.2, Peitsch M.2, Hoeng J.2

1Philip Morris International Research Laboratories, Department of Reduced-Risk Products, Singapore, Singapore 2Philip Morris International R&D, Department of Reduced-Risk Products, Neuchatel, Switzerland

P011: Evaluation the intestinal barrier function patients with inflammatory bowel diseaseECCO '17 Barcelona
Year: 2017
Authors:

Abdulganieva D.*1, Mukhametova D.1, Koshkin S.2, Zinkevich O.3, Saphina N.3, Abdulkhakov S.1,2, Odintsova A.4, Koporulina M.3

1Kazan State Medical University, Kazan, Russian Federation 2Kazan (Volga region) Federal University, Kazan, Russian Federation 3Kazan State Medical Academy, Kazan, Russian Federation 4Republican Clinical Hospital, Kazan, Russian Federation

P012: Ral activation exacerbates colonic inflammation through the impairment of intestinal barrier function in experimental murine colitisECCO '17 Barcelona
Year: 2017
Authors:

Minami N.*1, Matsuura M.1, Yamamoto S.1, Honzawa Y.1, Yamada S.1, Koshikawa Y.1, Okabe M.1, Seno H.1, Horiuchi H.2, Nakase H.3

1Graduate School of Medicine, Kyoto University, Gastroenterology and Hepatology, Kyoto, Japan 2Institute of Development, Aging and Cancer, Tohoku University, Molecular and Cellular Biology, Sendai, Japan 3Sapporo Medical University School of Medicine, Gastroenterology and Hepatology, Sapporo, Japan

P013: Decreased fibrogenesis in CH25H knockout mice in a mouse model of intestinal fibrosisECCO '17 Barcelona
Year: 2017
Authors:

Raselli T., Wyss A., Gonzalez Alvarado M.N., Mamie C., Rogler G., Hausmann M., Misselwitz B.

University of Zurich, Gastroenterology and Hepatology, Zurich, Switzerland

P014: Mucosal lymphocyte subsets in ulcerative colitis at diagnosis and during follow-upECCO '17 Barcelona
Year: 2017
Authors:

Smids C.*1, Horjus Talabur Horje C.1, Groenen M.1, van Koolwijk E.2, Wahab P.1, van Lochem E.2

1Rijnstate Hospital, IBD Centre, Gastroenterology and Hepatology, Arnhem, Netherlands 2Rijnstate Hospital, Microbiology and Immunology, Arnhem, Netherlands

P015: Wnt10b promotes fibrosis in murine colitisECCO '17 Barcelona
Year: 2017
Authors:

Ortiz-Masia D.*1,2, Salvador P.3, Macias-Ceja D.C.4, Gisbert-Ferrándiz L.3, Hernandez C.4, Calatayud S.3, Esplugues J.V.3,4, Barrachina D.3

1Universidad de Valencia-CIBERehd, Department of Pharmacology, Valencia, Spain 2Universidad de Valencia, Department of Medicine, Valencia, Spain 3Universidad de Valencia, Department of Pharmacology, Valencia, Spain 4FISABIO Hospital Peset, Department of Pharmacology, Valencia, Spain

P016: Pregnancy in IBD: direct effect of sex-hormones on epithelial barrier functionECCO '17 Barcelona
Year: 2017
Authors:

van der Giessen J., van der Woude C., Peppelenbosch M., Fuhler G.

Erasmus Medical Center, Gastroenterology and Hepatology, Rotterdam, Netherlands

P017: OGR1 (GPR68) expression is increased in intestinal inflammation and correlates with disease activity in patients with IBDECCO '17 Barcelona
Year: 2017
Authors:

Cosin-Roger J.1, Bengs S.1, Lang S.1, Turina M.2, Rickenbacher A.2, Seuwen K.3, Ruiz P.A.1, Misselwitz B.1, Rogler G.1, de Vallière C.*1

1University Hospital Zurich, University of Zurich, Gastroenterology and Hepatology, Zurich, Switzerland 2University Hospital Zurich, Clinic of Visceral and Transplantation Surgery, Zurich, Switzerland 3Novartis Institutes for Biomedical Research, Basel, Switzerland

P018: Complete metabonomic and microbiota profiling identifies biomarkers for anti-TNF therapy responseECCO '17 Barcelona
Year: 2017
Authors:

Ding N.S.*1,2,3, Sarafian M.3,4, Perdones-Montero A.5, Misra R.4, Hendy P.4, Penez L.4, Holmes E.3, Hart A.3,4

1St Vincent's Hospital, Inflammatory Bowel Disease, Melbourne, Australia 2St Mark's Hospital, Inflammatory Bowel Disease Unit, London, United Kingdom 3Imperial College London, Department of Surgery and Cancer, London, United Kingdom 4St Mark's Hospital, IBD, London, United Kingdom 5Imperial College, Surgery and Cancer, London, United Kingdom

P019: Anti-TNF-alpha therapy induces microbial and immunological changes in dextran sodium sulphate chronic colitisECCO '17 Barcelona
Year: 2017
Authors:

Petito V.*1, Graziani C.1, Lopetuso L.1, Quaranta G.2, Paroni Sterbini F.2, Masucci L.2, Sgambato A.3, Cammarota G.1, Sanguinetti M.2, Gasbarrini A.1, Scaldaferri F.1

1Fondazione Policlinico Universitario Gemelli, Catholic University of Sacred Heart, Gastroenterological Area, Gastroenterological and Endocrino-Metabolical Sciences Department, ROME, Italy 2Catholic University of Sacread Hearth, “A. Gemelli” Hospital, Department of Microbiology, Rome, Italy 3Catholic University of Sacred Heart of Rome, Department of Pathology, Rome, Italy

P020: Wnt5b could contribute to regeneration of the epithelium in inflammatory bowel disease by potentiating epithelial mesenchymal transitionECCO '17 Barcelona
Year: 2017
Authors:

Dotti I.*1, Ferrer-Picόn E.1, Planell N.1,2, van Herk E.H.3, Cuatrecasas M.4, Panés J.5, Salas A.1

1IDIBAPS, Experimental Gastroenterology, Barcelona, Spain 2CIBERehd, Barcelona, Spain 3Academic Medical Center (AMC), Tytgat Institute for Liver and Intestinal Research, Amsterdam, Netherlands 4Hospital Clinic de Barcelona, Department of Pathology, Barcelona, Spain 5Hospital Clinic de Barcelona, Department of Gastroenterology, Barcelona, Spain

P021: Utility of therapeutic anti-TNF drug monitoring in hospitals with different degree of experience in the treatment of inflammatory bowel diseaseECCO '17 Barcelona
Year: 2017
Authors:

Vila M.*1, Bahi A.1, Miquel J.O.2, Busquets D.3, Salό J.2, Aldeguer X.3

1Dr. Josep Trueta University Hospital, Institute of biomedical investigation of Girona, Girona, Spain 2Vic University Hospital, Gastroenterology, Vic, Spain 3Dr. Josep Trueta University Hospital, Gastroenterology, Girona, Spain

P022: MET deletion in MRP8+ neutrophils is protective during DDS-induced colitis via Th17 pathwayECCO '17 Barcelona
Year: 2017
Authors:

Stakenborg M., Meroni E., Goverse G., Matteoli G.

KU Leuven, P.O. Box 701, Department of Clinical and Experimental Medicine, Leuven, Belgium

P023: Fatigue in quiescent inflammatory bowel disease is associated with low GM-CSF levels and metabolomic alterationsECCO '17 Barcelona
Year: 2017
Authors:

Borren N.*1,2, Goel G.3,4, Lassen K.1, Devaney K.1, Cleland T.1, Garber J.1,4, Khalili H.1,4, Yajnik V.1,4, Xavier R.1,4, Ananthakrishnan A.1,4

1Massachusetts General Hospital, Department of Gastroenterology, Boston, United States 2University of Groningen, Groningen, Netherlands 3Massachusetts General Hospital, Boston, United States 4Harvard Medical School, Boston, United States

P024: Stratification of ulcerative colitis patients according to distinctive tissue cytokine profilesECCO '17 Barcelona
Year: 2017
Authors:

Butera A.*1, De Nitto D.2, Ciamberlano B.3, Giuliani A.4, Pica R.2, Pronio A.5, Boirivant M.1

1Istituto Superiore di Sanità, Dept Infectious, Parasitic and Immune-mediated Diseases, Roma, Italy 2Sandro Pertini Hospital, IBD, GE Unit, Roma, Italy 3University “Sapienza”, Dept General Surgery, “P. Stefanini”, Rome, Italy 4Istituto Superiore di Sanità, Dept Environment and Health, Rome, Italy 5University “Sapienza”, Dept. General Surgery, “P. Stefanini”, Roma, Italy

P025: Transcriptional and molecular pathways activated in mesenteric adipose tissue and intestinal mucosa of Crohn's disease patientsECCO '17 Barcelona
Year: 2017
Authors:

Coope A.1, Pascoal L.B.1, Silva F.A.R.1, Botezelli J.D.1, Ayrizono M.L.S.1, Milanski M.2, Camargo M.G.1, Planell N.3, Portovedo M.2, Dias C.B.1, Fagundes J.J.1, Leal R.F.*1

1University of Campinas, Department of Surgery, IBD Research Laboratory, Campinas, Brazil 2University of Campinas, Cell Signaling Laboratory, Department of Internal Medicine, Campinas, Brazil 3IDIBAPS, CIBERehd, Bioinformatics Platform, Barcelona, Spain

P026: The role of fibrocytes in mesenteric Crohn's diseaseECCO '17 Barcelona
Year: 2017
Authors:

Kiernan M.G.*1, Sahebally S.M.1,2, Kiely P.A.1, Waldron D.2, Moloney M.3, Skelly M.3, Faul P.N.4, O'Leary D.P.2, Lowery A.J.1,2, Walsh L.G.1,2, Dunne C.P.1, Coffey J.C.1,2

1University of Limerick, Graduate Entry Medical School and Centre for Interventions in Infection, Inflammation and Immunity (4i), Limerick, Ireland 2University Hospitals Limerick, Department of Surgery, Limerick, Ireland 3University Hospitals Limerick, Department of Gastroenterology, Limerick, Ireland 4University Hospitals Limerick, Department of Pathology, Limerick, Ireland