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P475: Switching from infliximab originator to CT-P13 is not related to increased immunogenicity in IBD patients: a prospective case-control studyECCO '17 Barcelona
Year: 2017
Authors:

Fiorino G.*1, Radice S.1, Gilardi D.1, Correale C.1, Allocca M.1, Furfaro F.1, Alfieri M.1, Nagore D.2, Del Rio L.2, Pascual J.2, Martínez A.2, Danese S.1,3

1Humanitas Clinical and Research Center, Department of Gastroenterology, Milan, Italy 2Progenika Biopharma SA, R&D Department, Derio, Spain 3Humanitas University, Department of Biomedical Sciences, Milan, Italy

P476: Sigmoidostomy or Hartman's procedure during laparoscopic subtotal colectomy for acute colitis complicating inflammatory bowel disease? A comparative study in 129 consecutive patientsECCO '17 Barcelona
Year: 2017
Authors:

Mege D.*1, Buskens C.2, Maggiori L.1, Stellingwerf M.2, Bemelman W.2, Panis Y.1

1Beaujon Hospital, Colorectal Surgery, Clichy, France 2AMC, Digestive Surgery, Amsterdam, Netherlands

P478: The current place of probiotics in treatment of pouchitis: systematic reviewECCO '17 Barcelona
Year: 2017
Authors:

Lichtenstein L., Avni I., Ben-Bassat O.

Rabin Medical Center, Gastroenterology, Petach Tikva, Israel

P479: Shifting the shunters in a paediatric inflammatory bowel disease population: thiopurine dose splitting versus allopurinol and thiopurine co-therapyECCO '17 Barcelona
Year: 2017
Authors:

Chadokufa S.*1,2, Baycheva M.2, Sawney T.3, Acton N.4, Sider S.1, Shah N.2, Huggett B.4, Dziubak R.2, Kiparrissi F.1

1Great Ormond Street Hospital, Gastro, London, United Kingdom 2Great Ormond Street Hospital, Paediatric Gastroenterology, London, United Kingdom 3Great Ormond Street Hospital, London, United Kingdom 4Great Ormond Street, London, United Kingdom

P480: Characteristics of drug-induced lupus 2° to anti-TNF agents in inflammatory bowel disease patients and evolution after switch to a second anti-TNFECCO '17 Barcelona
Year: 2017
Authors:

Mañosa M.*1, Corrales G.1, Olivares D.2, Vicuña M.3, Aguas M.4, Busquets D.5, Tosca J.6, Llaό J.7, Mesonero F.8, García-Tejero I.9, Ferreiro R.10, Cabré E.1, Domènech E.1

1Hospital Universitari Germans Trias i Pujol and CIBERehd, Gastroenterology, Badalona, Spain 2H Clínico San Carlos, Gastroenterology, Madrid, Spain 3Complejo Hospitalario de Navarra, Gastroenterolgy, Pamplona, Spain 4Hospital La Fe, Gastroenterology, Valencia, Spain 5Hospital universitari de Girona. Dr Trueta, Gastroenterology, Girona, Spain 6Hospital Clínic de Valencia, Gastroenterology, Valencia, Spain 7Hospital Santa Creu i Sant Pau, Gastroenterology, Barcelona, Spain 8H Ramon y Cajal, Gastroenterology, Madrid, Spain 9H Santa Lucia, Gastroenterology, Cartagena, Spain 10Hospital Universitario de Santiago, Gastroenterology, Santiago de Compostela, Spain

P481: Serum levels of infliximab associate with early mucosal healing in Crohn's disease: different “therapeutic window” between post-induction and maintenance treatmentECCO '17 Barcelona
Year: 2017
Authors:

Feng T.1, Chen B.1, Mao R.1, Ben-Horin S.2, Chen M.*1

1The First Affiliated Hospital of Sun Yat-sen University, Department of Gastroenterology, Guangzhou, China 2Sheba Medical Center, Department of Gastroenterology, Tel Hashomer, Israel

P482: Early anti-TNF/immunomodulator therapy is associated with better clinical outcomes in Asian patients with Crohn's disease with poor prognostic factorsECCO '17 Barcelona
Year: 2017
Authors:

Oh E.H.*1, Oh K.1, Seo H.2, Chang K.2, Kim G.-U.2, Song E.M.2, Seo M.2, Lee H.-S.3, Kwon E.J.2,4, Hwang S.W.2,4, Park S.H.2,4, Yang D.-H.2, Kim K.-J.2,4, Byeon J.-S.2, Myung S.-J.2, Yang S.-K.2,4, Ye B.D.2,4

1University of Ulsan College of Medicine, Asan Medical Center, Department of Internal Medicine, Seoul, South Korea 2University of Ulsan College of Medicine, Asan Medical Center, Department of Gastroenterology, Seoul, South Korea 3University of Ulsan College of Medicine, Asan Medical Center, Health Screening and Promotion Center, Seoul, South Korea 4Asan Medical Center, University of Ulsan College of Medicine, Inflammatory Bowel Disease Center, Seoul, South Korea

P483: Relapse after discontinuation of the maintenance drug in patients with Ulcerative proctosigmoiditis: preliminary result of a prospective randomized trialECCO '17 Barcelona
Year: 2017
Authors:

Choi H.*1, Gweon T.-G.2, Lee B.-I.2, Lee K.-M.2, Kim S.-W.2, Kang S.-B.2, Ji J.-S.2, Han S.-W.2, Choi M.-G.2

1The Catholic University of Korea, Internal Medicine, Seoul, South Korea 2The Catholic University of Korea, Seoul, South Korea

P484: Dietary therapy using the Crohn's disease exclusion diet is a successful strategy for induction of remission in children and adults failing biological therapyECCO '17 Barcelona
Year: 2017
Authors:

Sigall Boneh R.*1, Sarbagili Shabat C.1, Boaz M.2,3, Levine A.1,4, Chermesh I.5, Ben Avraham S.1, Cohen Dolev N.1

1Wolfson Medical Center, Pediatric Gastroenterology and Nutrition Unit, Tel Aviv, Israel 2Wolfson Medical Center, Epidemiology and Research Unit, Tel Aviv, Israel 3Ariel University, Nutrition School of Health Sciences, Ariel, Israel 4Tel Aviv University, Tel Aviv, Israel 5Rambam health care campus, Gastroenterology, Haifa, Israel

P485: Dosing infliximab in Crohn's disease: Is adjustment for body size justified?ECCO '17 Barcelona
Year: 2017
Authors:

Grisic A.-M.*1,2, Huisinga W.3, Reinisch W.4, Kloft C.1

1Freie Universitaet Berlin, Department of Clinical Pharmacy and Biochemistry, Berlin, Germany 2Graduate Research Training Program PharMetrX, Berlin, Germany 3Universitaet Potsdam, Institute of Mathematics, Potsdam, Germany 4Medical University of Vienna, Department for Gastroenterology and Hepatology, Vienna, Austria

P486: Immunization status of children and adolescents with inflammatory bowel disease or autoimmune hepatitis in GermanyECCO '17 Barcelona
Year: 2017
Authors:

Cagol L.1, Frivolt K.2, Krahl A.3, Förster N.3, Lainka E.4, Gerner P.5, Ney D.6, Vermehren J.7, Trenkel S.8, Radke M.8, Koletzko S.2, Posovszky C.*1

1University Medical Center Ulm, Department for Pediatric and Adolescent Medicine, Ulm, Germany 2Ludwigs-Maximilians-University, Dr. von Hauner Children's Hospital, Munich, Germany 3Darmstädter Kinderkliniken Prinzessin Margaret, Darmstadt, Germany 4University Medical Center Essen, Department for Pediatric and Adolescent Medicine, Essen, Germany 5University Medical Center Freiburg, Department for Pediatric and Adolescent Medicine, Freiburg, Germany 6Katholisches Kinderkrankenhaus Wilhelmsstift, Hamburg, Germany 7University Medical Center Regensburg, Department for Pediatric and Adolescent Medicine, Regensburg, Germany 8Klinikum Westbrandenburg, Department for Pediatric and Adolescent Medicine, Potsdam, Germany

P487: Effectiveness and safety of CT-P13 under routine care in paediatric patients with inflammatory bowel diseaseECCO '17 Barcelona
Year: 2017
Authors:

Choe Y.H.*1, Yang H.R.2, Moon J.S.3, Ryoo E.4, Kim S.5, Lee J.H.6, Kim H.J.7, Park J.H.8, Kim M.J.9, Lee S.J.10, Lee S.Y.10

1Samsung medical center, Sungkyunkwan University School of Medicine, Department of Pediatrics, Seoul, South Korea 2Seoul National University Bundang Hospital, Department of Pediatrics, Seongnam, South Korea 3Seoul National University Hospital, Seoul, South Korea 4Gachon University Gil Medical center, Incheon, South Korea 5Severance Children's Hospital, Yonsei University College of Medicine, Department of Pediatrics, Seoul, South Korea 6Seoul Song Do Colorectal Hospital, Department of Internal Medicine, Seoul, South Korea 7Kyung Hee University College of Medicine, Department of Internal Medicine, Seoul, South Korea 8Pusan National University Yangsan Hospital, Pusan, South Korea 9Inje University Ilsan Paik Hospital, Department of Pediatrics, Goyang, South Korea 10CELLTRION, Inc., Incheon, South Korea

P488: Does Statin use reduce the risk of J-pouch related complications in patients with inflammatory bowel disease?ECCO '17 Barcelona
Year: 2017
Authors:

Kaimakliotis P., Lazarev M., Bayless T., Parian A., Brant S., Melia J., Truta B.

Johns Hopkins, Gastroenterology/Medicine, Baltimore, United States

P489: Double-dose infliximab therapy in Crohn's disease: appropriate time to evaluate the efficacy, long-term efficacy and safetyECCO '17 Barcelona
Year: 2017
Authors:

Kunisaki R., Nishio M., Ogashiwa T., Otake H., Inoue E., Kimura H.

Yokohama City University Medical Centre, Inflammatory Bowel Disease Centre, Yokohama, Japan

P490: A pilot study of the electronic patient portal “Patient Knows Best” for monitoring biologic therapy in inflammatory bowel diseaseECCO '17 Barcelona
Year: 2017
Authors:

Kamperidis N., O'Connor M., Crook K., Arebi N.

St Mark's Hospital, London, United Kingdom

P491: Comparison of the durability of response to subcutaneous anti-TNF therapy between ulcerative colitis and Crohn's diseaseECCO '17 Barcelona
Year: 2017
Authors:

Mellotte G.*1,2, McShane C.1,2, O'Connell J.1,2, Mc Kiernan S.1,2, Mac Carthy F.1,2, Kevans D.1,2

1St James's Hospital, Dublin, Ireland 2Trinity College, School of Medicine, Dublin, Ireland

P492: Cumulative safety signal review confirmed the established safety profile of Asacol™† (mesalazine)ECCO '17 Barcelona
Year: 2017
Authors:

Timeus S.*1, Marchi P.2

1Tillotts Pharma, Pharmacovigilance, Rheinfelden, Switzerland 2Tillotts Pharma, Medical Affairs, Rheinfelden, Switzerland

P493: Efficacy of anti-TNF for internal fistula in Crohn's disease – results from a retrospective multicenter cohort studyECCO '17 Barcelona
Year: 2017
Authors:

Kobayashi T.*1, Hishida A.2, Tanaka H.3, Bamba S.4, Yamada A.5, Toshimitsu F.6, Shinichiro S.7, Kamata N.8, Yoshino T.9, Hibi T.1 AIM Jr. Internal Fistula Study Group

1Kitasato University Kitasato Institute Hospital, Center for Advanced IBD Research and Treatment, Tokyo, Japan 2Nagoya University Graduate School of Medicine, Department of Preventive Medicine, Nagoya, Japan 3Sapporo Kosei General Hospital, IBD Center, Sapporo, Japan 4Shiga University of Medical Science, Division of Gastroenterology, Shiga, Japan 5Toho University Sakura Medical Center, Department of Internal Medicine, Chiba, Japan 6Tokyo Medical and Dental University, Department of Gastroenterology and Hepatology, Tokyo, Japan 7Osaka University Graduate School of Medicine, Department of Gastroenterology and Hepatology, Osaka, Japan 8Osaka City University Graduate School of Medicine, Department of Gastroenterology, Osaka, Japan 9Tazuke Kofukai Medical Research Institute Kitano Hospital, IBD Center, Osaka, Japan

P494: Multicentre cohort study to evaluate the need for re-intervention following multimodal treatment in Crohn's disease with perianal fistulaECCO '17 Barcelona
Year: 2017
Authors:

Sebastian S.*1,2, Black C.2, Pugliese D.3, Armuzzi A.3, Sahnan K.4, Elkady S.M.4, Katsanos K.H.5, Christodoulou D.K.5, Selinger C.6, Maconi G.7, Fiorino G.8, Kopylov U.9, Davidov Y.9, Bosca-Watts M.M.10, Ellul P.11, Muscat M.11, Karmiris K.12, Fearnhead N.S.13, Allgar V.14, Hart A.L.4, Ben-Horin S.9, Danese S.8

1Hull & East Yorkshire NHS Trust, Hull, United Kingdom 2Hull & East Yorkshire NHS Trust, IBD Unit, Hull, United Kingdom 3Gemelli Hospital Catholic University, Rome, Italy 4St Marks Hospital, London, United Kingdom 5University of Ioannina, Ioannina, Greece 6Leeds Teaching hospitals NHS Trust, Leeds, United Kingdom 7Louigi Sacco University Hospital, Milan, Italy 8Humanitas Research Hospital, Milan, Italy 9Sheba Medical Center, Tel-Aviv, Israel 10University Clinic Hospital, Valencia, Spain 11Mater Dei Hospital, Msida, Malta 12Venizeleio General Hospital, Crete, Greece 13Addenbrooks University Hospitals, Cambridge, United Kingdom 14University of York, York, United Kingdom

P495: Intensified infliximab rescue therapy for acute severe ulcerative colitis does not improve long term colectomy-free survivalECCO '17 Barcelona
Year: 2017
Authors:

Al Khoury A.*1, Chao C.-y.2, Aruljothy A.2, Wyse J.3, Bessissow T.2

1McGill University, Gastroenterology, Montreal, Canada 2McGill University Health Centre, Department of Gastroenterology, Montréal, Canada 3Jewish General Hospital, Department of Gastroentelrology, Montréal, Canada