¹APHP, Paris, France, ²Hopital Montfermeil, Montfermeil, France, ³Hopital Saint Louis, Paris, France, ⁴Hopital de Lille, Lille, France, ⁵Hopital Saint Antoine, Paris, France, ⁶Hopital de Cochin, Paris, France, ⁷Hopital de Nancy, Nancy, France, ⁸Hopital de Clermont Ferrand, Clermont-Ferrand, France, ⁹Hopital de Nice, Nice, France, ¹⁰Hopital Montpellier, Montpellier, France, ¹¹Hopital de Vendée, Vendée, France, ¹²CHIC, Créteil, France, ¹³Centre Hospitalier Annecy, Annecy, France, ¹⁴Hopital de Colmar, Colmar, France, ¹⁵Orange, Orange, France, ¹⁶Hopital de Nantes, Nantes, France, ¹⁷Hopital de Beaujon, Clichy, France, ¹⁸Hopital saint brieuc, Saint brieuc, France, ¹⁹Hopital de tours, Tours, France, ²⁰CH valenciennes, Valenciennes, France, ²¹hopital Quimper, Quimper, France, ²²Hopital Dreux, Dreux, France, ²³Hopital de Meaux, Meaux, France

¹Samsung Medical Center, Sungkyunkwan University School of Medicine, Department of medicine, Seoul, South Korea, ²Samsung Medical Center, Sungkyunkwan University School of Medicine, Statistics and Data Center, Seoul, South Korea, ³Samsung Medical Center, Sungkyunkwan University School of Medicine, Department of Social and Preventive Medicine, Seoul, South Korea

¹St George's Healthcare NHS Trust, Gastroenterology, London, UK, ²Imperial College London, School of Public Health, London, UK

¹UCL, Institute of Health Informatics, London, UK, ²Stanford University, Stanford, USA, ³UCL, Institute of Cardiovascular Sciences, London, UK

¹University of Edinburgh, Department of Child Life and Health, Edinburgh, UK, ²Royal Hospital For Sick Children, Department of Gastroenterology and Nutrition, Edinburgh, UK, ³Royal Hospital For Sick Children, Department of Paediatric Surgery, Edinburgh, UK

¹IBD clinical and research centre, Iscare, Prague, Czech Republic, ²Public Health, Epidemiology and Economic Health, Registre Epimad, Maison Régionale de la Recherche Clinique, Lille University and Hospital, Lille, France, ³Lille Inflammation Research International Center LIRIC - UMR 995 Inserm Lille 2 University, CHRU de Lille, Lille, France, ⁴Gastroenterology Unit, Epimad Registry, Hôpital Charles Nicolle, Rouen University Hospital, Rouen, France, ⁵Gastroenterology Unit, Hôpital Huriez, Lille University Hospital, Lille, France, ⁶Gastroenterology Unit, Rennes University Hospital, Rennes, France, ⁷Division of Gastroenterology, Hepatology and Nutrition, Department of Paediatrics, Lille University Jeanne de Flandre Children’s Hospital, University of Lille, Lille, France, ⁸Dermatology Unit, Hôpital Huriez, Lille University Hospital, Lille, France, ⁹Gastroenterology Unit, Inserm U954, Nancy University and Hospital, Nancy, France, ¹⁰Gastroenterology Unit, Epimad Registry, CHU Amiens Sud, l, Amiens University Hospital, Amiens, France

¹Inselspital, Bern, Department of Gastroenterology, Bern, Switzerland, ²Universitätsspital, Gastroenterology, Zürich, Switzerland, ³Stadtspital Triemli, Gastroenterology, Zürich, Switzerland, ⁴CHUV, Gastroenterology, Lausanne, Switzerland, ⁵CHUV, PMU, Lausanne, Switzerland, ⁶CHUV, Statistics, Lausanne, Switzerland, ⁷Hôpital Saint-Louis, Gastroenterology, Lausanne, France, ⁸Inselpital, Gastroenterology, Bern, Switzerland, ⁹Inselspital, Gastroenterology, Bern, Switzerland

¹Seoul National University College of Medicine, Department of Internal Medicine, Seoul, South Korea, ²College of Medicine, The Catholic University of Korea, Dept of Medical Statistics, Seoul, South Korea

¹Gastroenterology Section, Hospital Ramón y Cajal, Madrid, Spain, ²Hospital Universitario Virgen Macarena, Sevilla, Spain, ³Unitat de Malalties Digestives. Corporació Sanitaria Universitària Parc Taulí, Sabadell, Spain, ⁴Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain, ⁵Merck Sharp & Dohme, Spain, Medical Affairs, Madrid, Spain, ⁶Servicio de Gastroenterología Complexo Hospitalario Universitario de Pontevedra, Pontevedra, Spain, ⁷Instituto de Investigación Biomedica (IBI). SERGAS, Pontevedra, Spain

¹Montefiore Medical Center, Bronx, USA, ²Albert Einstein College of Medicine, Bronx, USA, ³Weill Cornell Medical College, New York, USA, ⁴Icahn School of Medicine at Mount Sinai, New York, USA, ⁵Columbia University Medical Center, New York, USA

¹University Hospital of Burgos, Department of Gastroenterology, Burgos, Spain, ²University Hospital Rio Hortega, Department of Gastroenterology, Valladolid, Spain, ³University Hospital Clinic Valladolid, Department of Gastroenterology, Valladolid, Spain, ⁴Hospital Virgen de la Concha, Department of Gastroenterology, Zamora, Spain

¹University of Szeged, 1st Department of Medicine, Szeged, Hungary, ²University of Szeged, Department of Medical Physics and Informatics, Szeged, Hungary

¹Universitary Hospital A Coruna, Gastroenterology, A Coruna, Spain, ²Universitary Hospital A Coruna, A Coruna, Spain, ³Universitary Hospital A Coruna, Tuberculosis Unit, A Coruna, Spain

¹Servicio de Gastroenterología Complexo Hospitalario Universitario de Pontevedra, Pontevedra, Spain, ²Instituto de Investigación Biomedica (IBI). SERGAS, Pontevedra, Spain, ³Hospital Universitario Virgen Macarena, Sevilla, Spain, ⁴Unitat de Malalties Digestives. Corporació Sanitaria Universitària Parc Taulí, Sabadell, Spain, ⁵Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain, ⁶Merck Sharp & Dohme, Spain, Medical Affairs, Madrid, Spain, ⁷Gastroenterology Section, Hospital Ramón y Cajal, Madrid, Spain

¹University Medical Centre Groningen, Gastroenterology, Groningen, The Netherlands, ²University Medical Centre Groningen, Epidemiology, Groningen, The Netherlands, ³University Medical Centre Groningen, Genetics, Groningen, The Netherlands, ⁴Wageningen University and Research, Food and Nutrition, Wageningen, The Netherlands

¹Vestre Viken Hospital Trust, Baerum Hospital Medical Division, Drammen, Norway, ²University of Oslo, Institute of Clinical Medicine, Oslo, Norway, ³Oslo University Hospital, Department of Gastroenterology, Oslo, Norway, ⁴Akershus University Hospital, Department of Gastroenterology, Lørenskog, Norway, ⁵Oslo University College of Applied Sciences, Oslo, Norway, ⁶Stavanger University Hospital, Department of Gastroenterology, Stavanger, Norway, ⁷Ålesund Hospital Trust, Department of Medicine, Ålesund, Norway, ⁸Telemark Hospital Trust, Department of Research and Development, Skien, Norway, ⁹Innlandet Hospital Trust, Department of Medicine, Gjøvik, Norway, ¹⁰Innlandet Hospital Trust, Department of Medicine, Hamar, Norway, ¹¹Vestfold Hospital Trust, Department of Research and Development, Tønsberg, Norway, ¹²Østfold Hospital Trust, Department of Gastroenterology, Grålum, Norway, ¹³Østfold University College, Department of Health Sciences, Fredrikstad, Norway

¹University of Wolverhampton, Psychology, Wolverhampton, UK, ²University of Bath, Department of Pharmacy and Pharmacology, Bath, UK, ³Kings College London, Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, London, UK, ⁴St James University Hospital, Gastroenterology, Leeds, UK, ⁵Royal Wolverhampton NHS Trust, Gastroenterology, Wolverhampton, UK

¹Clinical Hospital No.2 Rzeszow, Poland#8232;, Department of Internal Medicine, Endocrinology, Nephrology, Rzeszów, Poland, ²Clinical Hospital No.2 Rzeszow, Poland#8232;, Department of Gastroenterology with the Central Department of Endoscopy, Rzeszów, Poland, ³Faculty of Medicine, University of Rzeszow, Poland, Rzeszów, Poland, ⁴Steele Children's Research Center, Arizona Health Sciences Center, University of Arizona, Steele Children's Research Center, Departments of Pediatrics and Immunobiology, Arizona, USA

¹Inselspital, Bern, Department of Gastroenterology, Bern, Switzerland, ²Universitätsspital, Gastroenterology, Zürich, Switzerland, ³CHUV, Gastroenterology, Lausanne, Switzerland, ⁴Stadtspital Triemli, Gastroenterology, Zürich, Switzerland, ⁵CHUV, PMU, Lausanne, Switzerland, ⁶CHUV, Statistics, Lausanne, Switzerland, ⁷Hôpital Saint-Louis, Gastroenterology, Lausanne, France, ⁸Inselpital, Gastroenterology, Bern, Switzerland, ⁹Inselspital, Gastroenterology, Bern, Switzerland

¹IRCCS Policlinico S. Matteo, Pavia, Italy, ²AOU Policlinico, Messina, Italy, ³Azienda Ospedaliera di Padova, Padova, Italy, ⁴AUO S. Giovanni di Dio e Ruggi D’Aragona, Salerno, Italy, ⁵Casa Sollievo Sofferenza, San Giovanni Rotondo, Italy, ⁶Università di Napoli Federico I, Napoli, Italy, ⁷Policlinico, Bari, Italy, ⁸Spedali Civili di Brescia, Brescia, Italy, ⁹Ospedale di Rivoli, Torino, Italy, ¹⁰AOU Careggi, Firenze, Italy, ¹¹AO S. Camillo Forlanini, Roma, Italy, ¹²AOU Seconda Università di Napoli, Napoli, Italy, ¹³IRCCS S. Martino, Genova, Italy, ¹⁴Università di Perugia, Perugia, Italy, ¹⁵AOU Trieste, Trieste, Italy, ¹⁶Policlinico Umberto I, Roma, Italy, ¹⁷AO S. Croce, Cuneo, Italy, ¹⁸Ospedale S. Maria del Prato, Feltre, Italy, ¹⁹Policlinico di Modena, Modena, Italy, ²⁰Ospedale SS Annunziata, Chieti, Italy, ²¹Ospedale Centrale di Bolzano, Bolzano, Italy