P176: TYK2 inhibition attenuates the stimulation of sensory neurons with hyper-IL-6ECCO'24Year: 2024
Authors: Pritchard, T.(1);Meng, M.(1);Higham, J.(1);Bulmer, D.(2)*;
(1)University of Cambridge, Pharmacology, Cambridge, United Kingdom;(2)University of Cambridge, Department of Pharmacology, Cambridge, United Kingdom;
P177: Beta-CGRP in inflammatory bowel disease: a protective neuropeptide of the gutECCO'24Year: 2024
Authors: Pascual, M.(1)*;Gárate, G.(2);Serrano, M.S.(1);González-Quintanilla, V.(2);García, M.J.(1);Castro Senosiain, B.(1);Crespo, J.(1);Pascual, J.(2);Rivero Tirado, M.(1);
(1)Valdecilla Research Institute IDIVAL- Universidad de Cantabria UC- Marqués de Valdecilla University Hospital, Gastroenterology and Hepatology Department- Clinical and Translational Research in Digestive Diseases, Santander, Spain;(2)Valdecilla Research Institute IDIVAL- Universidad de Cantabria UC- Marqués de Valdecilla University Hospital, Neurology, Santander, Spain;
P178: Changes in composition and structure of ileal mucus in Crohn’s disease patients compared to healthy controlsECCO'24Year: 2024
Authors: Kramer, C.(1)*;Rulff, H.(2);Kuppe, A.(3);Addante, A.(3);Fentker, K.(4);Ziegler, J.(1);Bischoff, P.(5);Gradzielski, M.(2);Mertins, P.(4);Mall, M.(3);Glauben, R.(1);Siegmund, B.(1);
(1)Charité - Universitätsmedizin Berlin, Medical Department of Gastroenterology- Infectiology and Rheumatology, Berlin, Germany;(2)Institut für Chemie, Stranski-Laboratorium für Physikalische und Theoretische Chemie, Berlin, Germany;(3)Charité - Universitätsmedizin Berlin, Department of Pediatric Respiratory Medicine- Immunology and Critical Care Medicine, Berlin, Germany;(4)Max Delbrück Center for Molecular Medicine in the Helmholtz Society and Berlin Institute of Health, Proteomics, Berlin, Germany;(5)Charité - Universitätsmedizin Berlin, Institute of Pathology, Berlin, Germany;
P179: Decrease in Butyric Acid in fecal matter in patients with Inflammatory Bowel Disease is associated with the levels of secretory Immunoglobulin A and fecal calprotectinECCO'24Year: 2024
Authors: Parra Izquierdo, L.V.(1)*;de Avila, J.(1);Ramos, A.(1);Chila-Moreno, L.(2);Bello-Gualtero, J.M.(2);Valdes, A.(3);Morantes, S.(4);Madroñero, J.(5);Bautista-Molano, W.(6);Delgado, F.(5);Florez-Sarmiento, C.(7);Romero-Sanchez, C.(8);
(1)Universidad El Bosque- Cellular and Molecular Immunology Group/INMUBO- Bogotá-Colombia., Immunology, Bogota, Colombia;(2)Universidad Militar Nueva Granada- Faculty of Medicine- Applied Clinical Immunology Group- Bogota-Colombia., Immunology, Bogota, Colombia;(3)Instituto de Investigación en Ciencias de la Alimentación- CIAL CSIC-UAM- Madrid- Spain., Research, Madrid, Spain;(4)Universidad El Bosque- Pharmaceutical Chemistry Programme- Applied Chemistry Research Group-INQA- Bogota- Colombia., Pharmaceutical Chemistry, Bogota, Colombia;(5)Universidad El Bosque- Instituto de Virología- Vicerrectoría de Investigaciones- Bogotá- Colombia, Virology, Bogota, Colombia;(6)Universidad Militar Nueva Granada- Faculty of Medicine- Applied Clinical Immunology Group- Bogota-Colombia, Immunology, Bogota, Colombia;(7)Hospital Internacional de Colombia- Bucaramanga- Colombia., Gastroenterology, Bogota, Colombia;(8)Universidad El Bosque- Cellular and Molecular Immunology Group/INMUBO- Bogotá-Colombia, Immunology, Bogota, Colombia;
P180: Novel biomarkers associated with inflammatory bowel diseaseECCO'24Year: 2024
Authors: Baldan-Martin, M.(1)*;lloro, I.(2);Azkargorta, M.(2);Orejudo, M.(1);Ramírez, C.(1);Soleto, I.(1);Mercado, J.(1);Suárez-Trujillo, F.(1);Sánchez-Sánchez, C.(1);Gordillo-Vélez, C.H.(3);Riestra, S.(4);Rivero, M.(5);Gutiérrez, A.(6);Rodríguez-Lago, I.(7);Fernández-Salazar, L.(8);Ceballos, D.(9);Benítez, J.M.(10);Aguas , M.(11);Bastón Rey, I.(12);Bermejo, F.(13);Casanova, M.J.(1);Lorente, R.(14);Ber, Y.(15);Royo, V.(16);Esteve, M.(17);Elortza, F.(2);Gisbert*, J.P.(1);Chaparro*, M.(1);
(1)Hospital Universitario de La Princesa- Instituto de Investigación Sanitaria Princesa IIS-Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBERehd- Madrid. Spain, Gastroenterology Unit, Madrid Madrid, Spain;(2)CIC bioGUNE- BRTA Basque Research & Technology Alliance- CIBERehd, Proteomics Platform, Derio, Spain;(3)Hospital Universitario de La Princesa, Anatomía Patológica, Madrid, Spain;(4)Hospital Universitario Central de Asturias and Instituto de Investigación sanitaria del Principado de Asturias ISPA, Gastroenterology Unit, Oviedo, Spain;(5)Hospital Universitario Marqués de Valdecilla and IDIVAL, Gastroenterology Unit, Santander, Spain;(6)Hospital General Universitario de Alicante- ISABIAL and CIBERehd, Gastroenterology Unit, Alicante, Spain;(7)Hospital Galdakao-Usansolo, Gastroenterology Unit, Vizcaya, Spain;(8)Hospital Clínico Universitario de Valladolid, Gastroenterology Unit, Valladolid, Spain;(9)Hospital Universitario de Gran Canaria Dr. Negrín, Gastroenterology Unit, Las Palmas de Gran Canaria, Spain;(10)Hospital Universitario Reina Sofía and IMIBIC, Gastroenterology Unit, Córdoba, Spain;(11)Hospital Universitari i Politecnic La Fe and Health Research Institute IISLaFe, Gastroenterology Unit, Valencia, Spain;(12)Hospital Clínico Universitario de Santiago, Gastroenterology Unit, Santiago de Compostela, Spain;(13)Hospital Universitario de Fuenlabrada, Gastroenterology Unit, Madrid, Spain;(14)Hospital General Universitario de Ciudad Real, Gastroenterology Unit, Ciudad Real, Spain;(15)Hospital San Jorge- Huesca, Gastroenterology Unit, Huesca, Spain;(16)Hospital Universitari Son Espases, Gastroenterology Unit, Palma de Mallorca, Spain;(17)Hospital Universitari Mutua Terrasa- Terrasa- and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBERehd, Gastroenterology Unit, Madrid, Spain;* Authors share co-senior authorship
P181: Combination of EPIC-CD epigenetic signatures accurately identifies non-response to multiple biologics in patients with active Crohn’s diseaseECCO'24Year: 2024
Authors: JoustraMD., V.(1)*;Li Yim, A.(2,3);Henneman, P.(3);Ishtu, H.(1,2);de Waard, T.(4);Evgeni, L.(4);Noble, A.(5);van Zon, S.(1);Chapman, T.(5,6);McGregor, C.(5);Adams, A.(5);Satsangi, J.(5);de Jonge, W.(2,7);D@E@Haens, G.(1);
(1)Amsterdam UMC - University of Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands;(2)Amsterdam UMC - University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam, The Netherlands;(3)Amsterdam UMC - University of Amsterdam- Genome Diagnostics Laboratory, Department of Human Genetics, Amsterdam, The Netherlands;(4)Horaizon BV, Horaizon, Delft, The Netherlands;(5)Oxford University Hospitals NHS Foundation Trust - John Radcliffe Hospital, Translational Gastroenterology Unit & NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom;(6)St Richard’s and Worthing Hospitals- University Hospitals Sussex NHS Foundation Trust, Department of Gastroenterology, West Sussex, United Kingdom;(7)University of Bonn, Department of Surgery, Bonn, Germany;EPIC-CD Consortium
P182: Hepatic lesions in chronic inflammatory bowel disease revealed by liver biopsy during surgery.ECCO'24Year: 2024
Authors: Siham, B.(1)*;zazour, A.(2);koulali, H.(2);Ismaili, Z.(2);Kharrasse, G.(3);
(1)service d@E@hépato-gastro-entérologie, CHU mohamed VI, oujda, Morocco;(2)service d@E@hépato-gastro-entérologie, CHU mohammed VI, oujda, Morocco;(3)service d@E@hépato-gastro-entérologie, oujda, oujda, Morocco;
P183: Therapeutic Effects of Curcumin and Ginsenoside Combination in a Animal Model of Radiation ProctitisECCO'24Year: 2024
Authors: Kim, S.E.(1)*;Kim, M.S.(2);Lee, R.A.(3);Yang, S.J.(2);Lim, H.(4);Lee, T.Y.(2);Woo, S.Y.(5);
(1)EWHA Womans University- Mokdong Hospital, Department of Internal Medicine, Seoul, Korea- Republic Of;(2)CORESTEMCHEMON Inc., Central Research Center, Seoul, Korea- Republic Of;(3)Ewha Womans University- College of Medicine- Seoul- South Korea, Department of Surgery, Seoul, Korea- Republic Of;(4)Ewha Womans University- College of Medicine, Department of Internal Medicine, Seoul, Korea- Republic Of;(5)Ewha Womans University- College of Medicine, Department of Microbiology, Seoul, Korea- Republic Of;
P186: Comparative Analysis of Clinical Phenotypes and Pathogenic Features between Late-Onset and Infantile-Onset Monogenic Inflammatory Bowel DiseaseECCO'24Year: 2024
Authors: Xiao, F.(1)*;Liu, H.(2);Xu, J.(2);Shen, Y.(2);Liao, J.(2);
(1)Tongji Hospital- Tongji Medical College- Huazhong University of Science and Technology, Department of Gastroenterology-, Wuhan, China;(2)Tongji Hospital- Tongji Medical College- Huazhong University of Science and Technology, Department of Gastroenterology, Wuhan, China;
P187: Validation of Disease Severity Index for Predicting Complicated Disease in Crohn’s Disease: A comparison study with Lémann IndexECCO'24Year: 2024
Authors: Zhou, L.(1)*;Qiu, Y.(1);Lu, B.(2);Lin, X.(1);Chen, B.(1);He, Y.(1);Zeng, Z.(1);Chen, M.(1);Li, X.(2);Mao, R.(1);
(1)The First Affiliated Hospital of Sun Yat-sen University, Department of Gastroenterology, Guangzhou, China;(2)The First Affiliated Hospital of Sun Yat-sen University, Department of Radiology, Guangzhou, China;
P188: Cumulative inflammatory burden as a risk factor for colorectal neoplasia in inflammatory bowel disease patients with primary sclerosing cholangitis: a multi-center case-control studyECCO'24Year: 2024
Authors: Van Lierop, L.(1,2)*;Derks, M.E.W.(2);te Groen, M.(2);Tran, C.D.(1);Lytvyak, E.(1);Dijkstra, G.(3,4);Montano-Loza, A.J.(1);Hoentjen, F.(1,2);
(1)University of Alberta Hospital, Gastroenterology, Edmonton, Canada;(2)Radboud University Medical Center, Gastroenterology, Nijmegen, The Netherlands;(3)University Medical Center Groningen, Gastroenterology, Groningen, The Netherlands;(4)University of Groningen, Gastroenterology, Groningen, The Netherlands;
P189: Lifestyle and psychosocial factors in IBD; prevalence and patients’ perspectiveECCO'24Year: 2024
Authors: Demers, K.(1,2,3);Hendrix, E.M.B.(2,3)*;Rezazadeh Ardabili, A.(2,3);Bredero, Q.M.(4);van Bodegraven, A.A.(3,5);van der Horst, D.(6);Jonkers, D.M.A.E.(2);Kimman, M.L.(7);Mujagic, Z.(2,3);Romberg-Camps, M.J.(5);Römkens, T.E.H.(8);Scherpenzeel, M.P.(6);Schroevers, M.J.(4);Stassen, L.P.S.(1,2);West, R.L.(9);Dijkstra, G.(10);Pierik, M.J.(2,3);
(1)Maastricht University Medical Center+, Department of Surgery, Maastricht, The Netherlands;(2)Maastricht University, Research Institute for Nutrition and Translational Research in Metabolism NUTRIM, Maastricht, The Netherlands;(3)Maastricht University Medical Center+, Department of Gastroenterology and Hepatology, Maastricht, The Netherlands;(4)University Medical Centre Groningen- University of Groningen, Department of Health Psychology, Groningen, The Netherlands;(5)Zuyderland Medical Centre, Department of Gastroenterology-Geriatrics-Internal and Intensive Care Medicine Co-MIK, Heerlen-Sittard-Geleen, The Netherlands;(6)Crohn & Colitis Netherlands, crohn-colitis.nl, Woerden, The Netherlands;(7)Maastricht University Medical Center+, Clinical Epidemiology and Medical Technology Assessment, Maastricht, The Netherlands;(8)Jeroen Bosch Hospital, Department of Gastroenterology and Hepatology, ‘s-Hertogenbosch, The Netherlands;(9)Franciscus Gasthuis & Vlietland, Department of Gastroenterology and Hepatology, Rotterdam, The Netherlands;(10)University Medical Center Groningen- University of Groningen, Department of Gastroenterology and Hepatology, Groningen, The Netherlands;
P190: Identification of clinical risk factors for postoperative endoscopic recurrence in Crohn’s disease: a prospective, multicenter cohort studyECCO'24Year: 2024
Authors: Bak, M.(1)*;Beelen , E.(1);van der Bilt, J.(2);Camps, M.(3);Dijkstra, G.(4);van der Marel, S.(5);Stassens, L.(6);Maljaars, J.(7);Buskens, C.(8);Jansen, S.(9);Jharap, B.(10);Horjus, C.(11);van Schaik, F.(12);West, R.(13);de Boer, N.(14);van der Woude, J.(1);van Ruler, O.(15);de Vries, A.(1);
(1)Erasmus University Medical Center Rotterdam, Department of Gastroenterology and Hepatology, Rotterdam, The Netherlands;(2)Flevoziekenhuis, Department of Surgery, Almere, The Netherlands;(3)Zuyderland Medical Center, Department of Gastroenterology and Hepatology, Heerlen-Sittard-Geleen, The Netherlands;(4)University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, The Netherlands;(5)Haaglanden Medical Center, Department of Gastroenterology and Hepatology, the Hague, The Netherlands;(6)Maastricht University Medical Center, Department of Surgery, Maastricht, The Netherlands;(7)Leiden University Medical Center, Department of Gastroenterology and Hepatology, Leiden, The Netherlands;(8)Amsterdam University Medical Center, Department of Surgery, Amsterdam, The Netherlands;(9)Reinier de Graaf Gasthuis, Department of Gastroenterology and Hepatology, Delft, The Netherlands;(10)Meander Medical Center, Department of Gastroenterology and Hepatology, Amersfoort, The Netherlands;(11)Rijnstate Hospital, Department of Gastroenterology and Hepatology, Arnhem, The Netherlands;(12)University Medical Center Utrecht, Department of Gastroenterology and Hepatology, Utrecht, The Netherlands;(13)Franciscus Gasthuis & Vlietland, Department of Gastroenterology and Hepatology, Rotterdam, The Netherlands;(14)Amsterdam University Medical Center, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands;(15)IJsselland Hospital, Department of Surgery, Capelle aan den IJssel, The Netherlands;on behalf of the RAP-CD study group on behalf of the Dutch Initiative on Crohn and Colitis (ICC) & Dutch Initiative on Crohn and Colitis – Surgery (ICC-S)
P191: Inflammatory bowel disease type unclassified in paediatric-onset IBD: A nationwide cohort study in Scotland with up to 20 years follow-up shows reclassification in the majority and mild course in those remaining as IBDUECCO'24Year: 2024
Authors: Wands, D.(1,2,3)*;Gianolio, L.(3);Cameron, F.(4);Hansen, R.(2,5);Russell, R.(1,3);Wilson, D.(1,3);
(1)University of Edinburgh, Child Life and Health- Centre for Inflammation Research, Edinburgh, United Kingdom;(2)Royal Hospital for Children, Paediatric Gastroenterology- Hepatology and Nutrition, Glasgow, United Kingdom;(3)Royal Hospital for Children and Young People, Paediatric Gastroenterology- Hepatology and Nutrition, Edinburgh, United Kingdom;(4)Alder Hey Children@E@s Hospital, Paediatric Gastroenterology- Hepatology and Nutrition, Liverpool, United Kingdom;(5)University of Dundee, Child Health- Division of Molecular and Clinical Medicine, Dundee, United Kingdom;
P192: Personalizing treatment for predicting response to infliximab in children with Crohn’s disease using proteomic biomarkersECCO'24Year: 2024
Authors: WinterMD, H.(1)*;Baldassano, R.N.(2);Pfeffkorn, M.D.(3);Wali, P.(4);Verstraete, S.G.(5);Picoraro, J.A.(6);Washek, M.A.(1);Kumar, N.(2);Mortan, W.(3);Havard- Jr, M.(3);Blystone, L.(4);Trombler, B.(5);Pursley, C.(1);Lin, X.(7);Dillon, S.T.(7);Gu, X.(7);Otu, H.H.(8);Ngo, L.(7);Libermann, T.A.(7);
(1)MassGeneral Hospital for Children, Paediatrics, Boston, United States;(2)Children@E@s Hospital of Philadelphia, Paediatrics, Philadelphia, United States;(3)Riley Children@E@s Hospital, Paediatrics, Indianapolis, United States;(4)Upstate Golisano Children’s Hospital, Paediatrics, Syracuse, United States;(5)University of California- San Francisco Medical Center, Paediatrics, San Francisco, United States;(6)Columbia University Irving Medical Center, Paediatrics, New York, United States;(7)Beth Israel Deaconess Medical Center, Medicine, Boston, United States;(8)University of Nebraska–Lincoln, Electrical and Computer Engineering, Lincoln, United States;
P193: Fatigued patients with Inflammatory Bowel Disease exhibit distinct systemic antibody epitope repertoiresECCO'24Year: 2024
Authors: Griesbaum, M.G.(1);Vogl, T.(2);Andreu-Sánchez, S.(3);Klompus, S.(4);Kalka, I.N.(4);Leviatan, S.(4);van Dullemen, H.M.(1);Visschedijk, M.C.(1);Festen, E.A.M.(1);Faber, K.N.(1);Dijkstra, G.(1);Weinberger, A.(4);Segal, E.(4);Weersma, R.K.(1);Bourgonje, A.R.(1,5)*;
(1)University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, The Netherlands;(2)Medical University of Vienna, Center for Cancer Research, Vienna, Austria;(3)University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands;(4)Weizmann Institute of Science, Department of Computer Science and Applied Mathematics and Department of Molecular Cell Biology, Rehovot, Israel;(5)Icahn School of Medicine at Mount Sinai, The Henry D. Janowitz Division of Gastroenterology- Department of Medicine, New York, United States;
P194: Health-related quality of life and fatigue in newly-diagnosed inflammatory bowel diseases: findings from a prospective population-based inception cohort, IBD Prognosis StudyECCO'24Year: 2024
Authors: Attauabi, M.(1,2,3)*;Roager Madsen, G.(2,3);Bendtsen, F.(2,3);Seidelin, J.(1);Burisch, J.(2,3);
(1)Copenhagen University Hospital - Herlev and Gentofte, Department of Gastroenterology and Hepatology, Herlev, Denmark;(2)Hvidovre Hospital, Copenhagen Center for Inflammatory Bowel Disease in Children- Adolescents- and Adults, Hvidovre, Denmark;(3)Copenhagen University Hospital - Amager and Hvidovre, Gastrounit- Medical Section, Hvidovre, Denmark;
P195: Prevalence and factors associated with fatigue in patients with inflammatory bowel diseaseECCO'24Year: 2024
Authors: Kallel, H.(1)*;Elleuch, N.(1);Limam, R.(1);Dahmeni, W.(1);Hammami, A.(1);Braham, A.(1);Ben Slama, A.(1);Jaziri, H.(1);Ksiaa, M.(1);
(1)Sahloul Hospital, Gastroenterology Department, Sousse, Tunisia;
