¹Leeds Teaching Hospitals, Leeds, UK, ²Royal London Hospital, Barts Health, London, UK, ³Salisbury NHS Foundation Trust, Salisbury, UK, ⁴St Helens and Knowsley Foundation Trust, St Helens, UK, ⁵Kingston Hospital NHS Foundation Trust, Kingston upon Thames, UK, ⁶Bristol Royal Infirmary, Bristol, UK, ⁷Torbay and South Devon NHS Trust, Torbay, UK, ⁸Wirral University Teaching Hospital, Birkenhead, UK, ⁹Royal Bolton Hospital, Bolton, UK, ¹⁰North Manchester General Hospital, Manchester, UK, ¹¹University Hospital Llandough, Cardiff, UK, ¹²University College London Hospitals, London, UK, ¹³Epsom and St Helier University Hospitals NHS Trust, Epsom, UK, ¹⁴St George's University Hospitals NHS Foundation Trust, London, UK, ¹⁵Forth Valley Royal Hospital, Larbert, UK, ¹⁶Royal United Hospitals Bath NHS Foundation Trust, Bath, UK, ¹⁷East Kent Hospitals University NHS Foundation Trust, Margate, UK, ¹⁸Brighton and Sussex University Hospitals NHS Trust, Brighton, UK, ¹⁹Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

¹Division of Internal Medicine, ''Villa Sofia-Cervello'' Hospital, Palermo, Italy, ²Inflammatory Bowel Disease Unit, A.O.U. Policlinico "G. Martino”, Messina, Italy, ³IBD Unit, A.O. "Cannizzaro”, Catania, Italy, ⁴Gastroenterology and Hepatology Unit, A.O.U. Policlinico “G. Giaccone”, Palermo, Italy, ⁵Gastroenterology Unit, A.R.N.A.S. “Garibaldi”, Catania, Italy, ⁶Internal Medicine Unit, A.O.U. Policlinico “Vittorio Emanuele”, Catania, Italy, ⁷Gastroenterology Unit, A.O.U. Policlinico “Vittorio Emanuele”, Catania, Italy, ⁸Gastroenterology and Endoscopy Unit, A.R.N.A.S. “Civico Di Cristina Benfratelli”, Palermo, Italy, ⁹Gastroenterology Unit, A.O. “Guzzardi”, Vittoria, Italy, ¹⁰Gastroenterology Unit, A.O.O.R. “S. Elia- M. Raimondi”, Caltanissetta, Italy, ¹¹Gastroenterology Unit, A.O. “Santa Marta e S. Venera”, Acireale, Italy, ¹²Surgery Unit, A.O. “Umberto I”, Siracusa, Italy, ¹³Internal Medicine Unit, A.O. “Giovanni Paolo II”, Sciacca, Italy, ¹⁴Gastroenterology and Endoscopy Unit, A.O. “S. Antonio Abate”, Trapani, Italy, ¹⁵Gastroenterology Unit, A.O.O.R. “Papardo Piemonte”, Messina, Italy, Messina, Italy, ¹⁶Gastroenterology and Endoscopy Unit, A.O. “Buccheri La Ferla Fatebenefratelli”, Palermo, Italy

¹Academic Medical Center (AMC), Department of Surgery, Amsterdam, The Netherlands, ²St Vincent's University Hospital, Department of Colorectal Disease, Dublin, Ireland, ³Academic Medical Center (AMC), Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands

¹CHU UCL Namur, Catholic University of Louvain, Gastroenterology and Hepatology, Yvoir, Belgium, ²University of Saint Etienne, Department of Gastroenterology, Saint Etienne, France, ³Faculty of Medicine of Saint-Etienne, University of Lyon, EA-3064, Groupe Immunité des Muqueuses et Agents Pathogènes (GIMAP), Lyon, France, ⁴CHU UCL Namur, Scientific Support Unit, Yvoir, Belgium, ⁵University of Saint Etienne, Laboratory of Infectious Agents and Hygiene, Saint Etienne, France

¹Bata Regional Hospital, Internal Clinic, Zlin, Czech Republic, ²Third Faculty of Medicine, Charles University in Prague, 2nd Department of Internal Medicine, Prague, Czech Republic, ³Third Faculty of Medicine, Charles University in Prague, 2nd Department of Internal Medicine, Prague, Czech Republic, ⁴Thomayer Hospital, 2nd Department of Internal Medicine, Prague, Czech Republic

¹Institute of Social and Preventive Medicine, Healthcare Evaluation Unit, Lausanne, Switzerland, ²Lausanne University Hospital, Department of Gastroenterology and Hepatology, Lausanne, Switzerland, ³Lindenhof Spital, Division of Gastroenterology, Bern, Switzerland, ⁴Institute of Social and Preventive Medicine, Centre for Integrative and Complementary Medicines, Lausanne, Switzerland

St Vincents University Hospital and School of Medicine, University College Dublin, Centre for Colorectal Disease, Dublin 4, Ireland

¹Gastro-entérologie La Source-Beaulieu and Division of Gastroenterology, Centre Hospitalier Universitaire Vaudois, Crohn and Colitis Center, Lausanne, Switzerland, ²Takeda Pharmaceuticals International AG, Zurich, Switzerland, ³Hôpital Saint-Louis, APHP, INSERM UMRS 1160, Université Denis Diderot, Gastroenterology and Hepatology, Paris, France

¹Erasmus MC, Sophia Children's Hospital, Paediatric Gastroenterology, Rotterdam, The Netherlands, ²Centre for Immunobiology, Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, Paediatric Gastroenterology, London, UK, ³Université Paris Descartes, Sorbonne Paris Cité, APHP, Hopital Necker Enfants Malades, Department of Paediatric Gastroenterology, Paris, France

¹Gangnam Severance Hospital, Yonsei University College of Medicine, Internal Medicine, Seoul, South Korea, ²Seoul National University College of Medicine, Preventive Medicine, Seoul, South Korea, ³Severance Hospital, Yonsei University College of Medicine, Internal Medicine, Seoul, South Korea

University of Chicago Medicine, Inflammatory Bowel Disease Center, Chicago, USA

¹Radboudumc, Nijmegen, The Netherlands, ²Maastricht University Medical Center (MUMC), Maastricht, The Netherlands, ³Erasmus Medical Center, Rotterdam, The Netherlands, ⁴University Medical Center Groningen, Groningen, The Netherlands, ⁵Leiden University Medical Center (LUMC), Department of Gastroenterology and Hepatology, Leiden, The Netherlands, ⁶University Medical Centre Utrecht, Utrecht, The Netherlands, ⁷VU University Medical Centre Institute of Education, Department of Gastroenterology and Hepatology, Room J393, Amsterdam, The Netherlands, ⁸Academic Medical Center (AMC), Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands, ⁹Radboudumc, Department of Gastroenterology and Hepatology, Nijmegen, The Netherlands

Mauriziano Hospital, Gastroenterology Unit, Torino, Italy

¹Nabeul-Tunisia, Department of Gastroenterology Nabeul-Tunisia, Nabeul, Tunisia, ²Nabeul-Tunisia, Nabeul-Tunisia, Nabeul, Tunisia, ³Mohamed Taher Maamouri Hospital, Department of Gastroenterology, Nabeul, Tunisia

¹New York Presbyterian Hospital, New York, USA, ²Aix-Marseille University, Marseille, France

¹The Alfred Centre, Department of Gastroenterology, Monash University, Melbourne, Australia, ²The Royal Melbourne Hospital, Department of Gastroenterology, Melbourne, Australia, ³Swinburne University, Psychological Sciences and Statistics, Hawthorn, Australia, ⁴AbbVie Pty Ltd., Immunology (Medical), Sydney, Australia

University College London Hospital, Department of Gastroenterology, London, UK

¹University Hospital Center Jean Minjoz, Gastroenterology, Besancon, France, ²Private Clinic Pasteur, Gastroenterology, Toulouse, France, ³University Hospital Center, Gastroenterology, Nantes, France, ⁴University Hospital Center, Gastroenterology, Lille, France, ⁵University Hospital Center, Gastroenterology, Caen, France, ⁶Private Practise, Gastroenterology, Montpellier, France, ⁷Private Clinic La Louviere, Gastroenterology, Lille, France, ⁸University Hospital Center, Gastroenterology, Rouen, France, ⁹Aphm North Hospital, Gastroenterology, Marseille, France, ¹⁰Private Practice, Gastroenterology, Toulon, France, ¹¹University Hospital Center Rangueil, Gastroenterology, Toulouse, France, ¹²Hospital Louis Pasteur, Gastroenterology, Colmar, France, ¹³Hospital Saint Louis APHP, Gastroenterology, Paris, France, ¹⁴Hospital Saint Antoine APHP, Gastroenterology, Paris, France, ¹⁵University Hospital Center Caremeau, Gastroenterology, Nimes, France, ¹⁶University Hospital Center, Gastroenterology, Saint Etienne, France, ¹⁷University Hospital Center Cochin APHP, Gastroenterology, Paris, France, ¹⁸University Hospital Center Brabois, Gastroenterology, Nancy, France, ¹⁹University Hospital Center Le Bocage, Gastroenterology, Dijon, France, ²⁰Hospital Haut Anjou, Gastroenterology, Chateau Gontier, France, ²¹Private Clinic Des cèdres, Gastroenterology, Cornebarrieu, France, ²²Private Practice, Gastroenterology, Belfort, France, ²³Private Hospital, Gastroenterology, Saint Priest en Jarez, France, ²⁴European Hospital Georges Pompidou APHP, Gastroenterology, Paris, France, ²⁵Hospital HNFC, Gastroenterology, Trevenans, France, ²⁶University Hospital Center Larchet, Gastroenterology, Nice, France, ²⁷University Hospital Henri Mondor APHP, Gastroenterology, Créteil, France, ²⁸Private Practice, Gastroenterology, Paris, France, ²⁹University Hospital Center Hôtel Dieu, Gastroenterology, Nantes, France, ³⁰Institut Mutualiste Montsouris, Gastroenterology, Paris, France

¹Hospital Clínic de Barcelona, IDIBAPS, CIBERehd, Gastroenterology Department, Barcelona, Spain, ²Faculty of Medicine, Autonomous University of Madrid, Department of Surgery, Madrid, Spain, ³Takeda Pharmaceuticals International Co., Cambridge, USA, ⁴Takeda Pharmaceuticals International AG, Zurich, Switzerland, ⁵Takeda Development Centre, London, UK

¹Örebro University, Department of Gastroenterology, Faculty of Medicine and Health, Örebro, Sweden, ²Hospital of Trelleborg, Department of Medicine, Division of Gastroenterology, Trelleborg, Sweden, ³Danderyd Hospital, Department of Internal Medicine, Stockholm, Sweden, ⁴Linköping University, Department of Gastroenterology and Department of Clinical and Experimental Medicine, Linköping, Sweden, ⁵Örebro University, Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine and Health, Örebro, Sweden, ⁶Karolinska Institute, Department of Medicine, Gastrocentrum, Stockholm, Sweden, ⁷Merck Sharp and Dohme, Sweden, Stockholm, Sweden, ⁸Skåne University Hospital, Department of Gastroenterology, Lund, Sweden, ⁹Södra Älvsborgs Hospital, Department of Internal Medicine, Borås, Sweden