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P456: Drug survival of thiopurine–allopurinol combination therapy in a real-life population-based cohortECCO '18 Vienna
Year: 2018
Authors:

J.E. Kreijne1*, R.C. de Veer1, N.K. de Boer2, G. Bouma2, G. Dijkstra3, R.L. West4, A.A. van Bodegraven5, D.J. de Jong6, C.J. van der Woude1, A.C. de Vries1

1Erasmus MC, Gastroenterology and Hepatology, Rotterdam, The Netherlands, 2VU University Medical Centre, Gastroenterology and Hepatology, Amsterdam, The Netherlands, 3University Medical Center Groningen and University of Groningen, Gastroenterology and Hepatology, Groningen, The Netherlands, 4Franciscus Hospital and Vlietland Hospital, Gastroenterology and Hepatology, Rotterdam, The Netherlands, 5Zuyderland Medical Center, Clinical Gastroenterology and Hepatology, Heerlen-Sittard-Geleen, The Netherlands, 6Radboud University Nijmegen Medical Center, Gastroenterology and Hepatology, Nijmegen, The Netherlands

P457: Biological interventions for induction and maintenance of mucosal healing in ulcerative colitis: A Cochrane systematic reviewECCO '18 Vienna
Year: 2018
Authors:

A. Ricciuto1*, A. Al-Darmaki2, M.J. Stewart2, N.S. Ding3, H.H. Shim2, M. Storr4,5, R. Panaccione2, C. Seow2

1Hospital for Sick Children, University of Toronto, Toronto, Canada, 2University of Calgary, Medicine, Calgary, Canada, 3Imperial College Healthcare, London, UK, 4Ludwig-Maximilians-University Munich, Munich, Germany, 5Center of Endoscopy, Starnberg, Germany

P458: Long-term outcome of Crohn’s disease complicated by upper gastrointestinal stricture: A GETAID cohort studyECCO '18 Vienna
Year: 2018
Authors:

T. Lambin1*, A. Amiot2, J.M. Gornet3, P. Seksik4, D. Laharie5, E. Louis6, C. Giletta7, J. Filippi8, M. Fumery9, G. Cadiot10, G. Pineton de Chambrun11, S. Nahon12, M. Serrero13, B. Coffin14, L. Plastaras15, S. Viennot16, N. Dib17, L. Peyrin-Biroulet18, B. Pariente1

1Claude Huriez Hospital, Lille, France, 2Henri Mondor Hospital, Creteil, France, 3Saint Louis Hospital, Paris, France, 4Saint Antoine Hospital, Paris, France, 5Haut-Lévêque Hospital, Pessac, France, 6CHU Sart Tilman, Liège, Belgium, 7Rangueil Hospital, Toulouse, France, 8Hôpital de l'Archet, Nice, France, 9Hôpital Nord, Amiens, France, 10Robert Debré Hospital, Reims, France, 11Saint Eloi Hospital, Montpellier, France, 12CHI Le Raincy-Montfermeil, Montfermeil, France, 13Hôpital Nord, Marseille, France, 14Louis Mourier Hospital, Colombes, France, 15Louis Pasteur Hospital, Colmar, France, 16Hôpital Côte de Nacre, Caen, France, 17CHU Angers, Angers, France, 18Hôpital de Brabois, Vandoeuvre-les-Nancy, France

P459: Persistent mesorectal inflammatory activity is associated with complications after proctectomy in Crohn’s diseaseECCO '18 Vienna
Year: 2018
Authors:

E.J. de Groof1, J.H. van der Meer2,3*, P.J. Tanis1, J.R. de Bruyn2,3, O. van Ruler1, G.R. D'Haens3, G.R. van den Brink2,3,4, W.A. Bemelman1, M.E. Wildenberg2,3, C.J. Buskens1

1Academic Medical Center (AMC), Department of Surgery, Amsterdam, The Netherlands, 2Academic Medical Center (AMC), Tytgat Institute for Liver and Intestinal Research, Amsterdam, The Netherlands, 3Academic Medical Center (AMC), Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands, 4Currently GlaxoSmithKline, Medicines Research Center, Stevenage, UK

P460: Impact of anti-TNFα exposure during pregnancy for maternal inflammatory bowel disease on serologic response to vaccination of exposed childrenECCO '18 Vienna
Year: 2018
Authors:

D. Duricová1*, E. Dvorakova1, J. Kozeluhova2, P. Kohout3, K. Mitrova4, M. Durilova5, K. Zarubova4, O. Hradsky4, J. Bronsky4, N. Hradska6, E. Bronska6, N. Machkova1, V. Hruba1, M. Bortlik1, M. Lukas1, K. Malickova1, M. Lukas1

1IBD Clinical and Research Centre, Iscare, Prague, Czech Republic, 2Department of Internal Medicine, University Hospital Plzen, Plzen, Czech Republic, 3Department of Internal Medicine, Thomayer University Hospital, Prague, Czech Republic, 4Department of Paediatrics, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic, 5Department of Paediatric Surgery, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic, 6General Paediatrician, Prague, Czech Republic

P461: Post-marketing safety experience of vedolizumab in older patients with inflammatory bowel diseaseECCO '18 Vienna
Year: 2018
Authors:

S. Travis1, R. Ungaro2, A. Blake3, F. Bhayat4*, T. Card5

1Oxford University Hospital, Oxford, UK, 2Icahn School of Medicine at Mount Sinai, New York, USA, 3Takeda International - UK Branch, London, UK, 4Takeda Development Center Americas, Inc., Cambridge, USA, 5University of Nottingham, Nottingham, UK

P462: Mucosal healing and deep remission rates with azathioprine in inflammatory bowel disease?ECCO '18 Vienna
Year: 2018
Authors:

Ü. Dağlı*, D. Özer Etik, N. Demir, S. Öcal, H. Selçuk, F. Hilmioğlu, S. Boyacıoğlu

Başkent University Medical Faculty, Department of Gastroenterology, Ankara, Turkey

P463: Long-term effects of anti-TNF therapy on bone metabolismECCO '18 Vienna
Year: 2018
Authors:

N. O'Morain1*, G. Farrell1, M. Hanly1, S. Veerappan1, D. McNamara1,2, N. Breslin1, C. O'Morain2, M. Healy3, B. Ryan1,2

1Tallaght Hospital, Gastroenterology, Dublin, Ireland, 2Trinity College Dublin, Dublin, Ireland, 3St James's Hospital, Dublin, Ireland

P464: Switching from the originator infliximab to biosimilar CT-P13 did not change the quality of life and clinical efficacy for IBD patients in stable remission in daily clinical practice (interim analysis)ECCO '18 Vienna
Year: 2018
Authors:

M.J. Pierik1, A.E. van der Meulen-de Jong2, J.P.J. Bloemsaat-Minekus3*, Y.J.B. van Megen3, G. Dijkstra4

1Maastricht University Medical Center (MUMC), Maastricht, The Netherlands, 2Leiden University Medical Center (LUMC), Leiden, The Netherlands, 3Mundipharma Pharmaceuticals B.V., Leusden, The Netherlands, 4University Medical Center Groningen, Groningen, The Netherlands

P465: Do infliximab trough levels differ between adult and paediatric patients with Crohn’s disease in clinical remission?ECCO '18 Vienna
Year: 2018
Authors:

A. Cavazza1*, N. Mavroeidi1, A. Steel2, L. Greathead1, W. Kelleher1, M. Wahed1

1Chelsea and Westminster Hospital NHS Foundation Trust, London, UK, 2The Royal Liverpool University Hospital, Liverpool, UK

P466: Acetarsol is an effective and safe option in the management of refractory ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

K. Argyriou1*, R.J.M. Ingram1, R. Blatt2, P. Wilson2, S. Samuel1, C. Hawkey1, G.W. Moran1,3

1Nottingham Digestive Diseases Centre, Queens Medical Center Campus, Nottingham University Hospitals NHS Trust, Nottingham, UK, 2Pharmacy Department, Queens Medical Center Campus, Nottingham University Hospitals NHS Trust, Nottingham, UK, 3National Institute of Health Research Biomedical Research Centre in Gastrointestinal and Liver Diseases at Nottingham University Hospitals and the University of Nottingham, Nottingham, UK

P467: A comparison of thiopurines vs. anti-TNF-α therapy in steroid-dependent ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

S. Hosomi*, M. Ohira, H. Yamagami, R. Nakata, N. Sugita, Y. Nishida, S. Itani, T. Yukawa, N. Kamata, K. Otani, Y. Nagami, F. Tanaka, K. Taira, T. Tanigawa, T. Watanabe, Y. Fujiwara

Osaka City University Graduate School of Medicine, Gastroenterology, Osaka, Japan

P468: Microscopic colitis: systematic analysis of 200 adult patients with a mean follow-up of 4 yearsECCO '18 Vienna
Year: 2018
Authors:

H. Maye1*, E. Safroneeva2, S. Godat1, A. Schoepfer1

1CHUV - Centre Hospitalier Universitaire Vaudois, Department of Gastroenterology, Lausanne, Switzerland, 2Institute of Social and Preventive Medicine, Bern, Switzerland

P469: Self-reported cutaneous side effects of anti-TNF therapy in inflammatory bowel disease patientsECCO '18 Vienna
Year: 2018
Authors:

A. Ridge1*, C. Gallagher2, C. Judge1, J. Campion1, D. Mc Namara2,3,4, D. Kevans1,3,4

1St James's Hospital, Department of Gastroenterology, Dublin, Ireland, 2AMNCH, Tallaght, Dublin 24, Department of Gastroenterology, Dublin, Ireland, 3Trinity College Dublin, Trinity Academic Gastroenterology Group, Dublin, Ireland, 4Trinity College Dublin, School of Medicine, Dublin, Ireland

P470: Improving IBD-related pregnancy knowledge with a specialised preconception and pregnancy in IBD clinicECCO '18 Vienna
Year: 2018
Authors:

N. Rodriguez, L. Ambrosio, L. Dieleman, B. Halloran, K.I. Kroeker, F. Peerani, K. Wong, R.N. Fedorak, V.W. Huang*

University of Alberta, Gastroenterology, Edmonton, Canada

P471: Clinical characteristics and complications in hospitalised elderly patients with ulcerative colitis in a real-world specialised hospitalECCO '18 Vienna
Year: 2018
Authors:

Y. Kita1*, A. Fujimori1, R. Koshiba1, K. Fujimoto1, T. Sato1, M. Kawai2, K. Kamikozuru1, T. Takagawa2, Y. Yukoyama1, T. Miyazaki1, K. Watanabe2, N. Hida1, S. Nakamura1

1Hyogo College of Medicine, Department of Inflammatory Bowel Disease, Nishinomiya, Japan, 2Hyogo College of Medicine, Department of Intestinal Inflammation Research, Nishinomiya, Japan

P472: Impact of anti-TNF-alfa therapy on colectomy rates and indications for surgery in Ulcerative Colitis: Comparison of two patient cohorts from 2005 to 2007 and 2014 to 2016ECCO '18 Vienna
Year: 2018
Authors:

S. Kolehmainen1*, A. Lepistö2, M. Färkkilä1,3

1Helsinki University, Helsinki, Finland, 2Helsinki University Hospital, Abdominal Center, Helsinki, Finland, 3Helsinki University Hospital, Clinic of Gastroenterolgy, Helsinki, Finland

P473: Contrasting the use of 5-ASA in patients with Ulcerative Colitis and Crohn's Disease: A cross-sectional analysis at a tertiary care IBD clinicECCO '18 Vienna
Year: 2018
Authors:

M. Alkhattabi*, V. Jairath, N. Chande, P. Walton-Mennill, J. Gregor

London Health Sciences Centre,/University of Western Ontario, Division of Gastroenterology, Department of Medicine, London, Canada

P474: Efficacy and safety of anti-TNF and vedolizumab in liver transplant recipients with inflammatory bowel disease (IBD)ECCO '18 Vienna
Year: 2018
Authors:

C. Bellanger1*, L. Beaugerie2, A. Amiot3, S. Tezenas du Montcel4, C. Duvoux3, D. Samuel5, F. Carbonnel1

1APHP, Le Kremlin Bicetre, France, 2Saint Antoine, Paris, France, 3Henri Mondor, 94, Henri Mondor, France, 4Pitié-Salpétrière, Paris, France, 5Paul Brousse, Villejuif, France

P475: High prevalence of severe liver fibrosis in patients with longstanding IBDECCO '18 Vienna
Year: 2018
Authors:

M. Steenhuis, S. Van der Marel*, A. Van der Meulen- de Jong, J. Maljaars

LUMC, Gastroenterology-Hepatology, Leiden, The Netherlands