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P093: CD4 T-cell transcriptome analysis at baseline predicts clinical remission to anti-TNF agents in ulcerative colitis (UC)

ECCO '19 Copenhagen

Year: 2019

Authors:

S. Subramanian*¹, L. Rainbow², M. Gemmell², R. Hough³, S. Haldenby², A. Gureviciute¹, M. Lofthouse¹, K. Martin¹, C. Probert¹

¹Royal Liverpool University Hospital, Liverpool, UK, ²University of Liverpool, Center for genomics research, Liverpool, UK, ³Institute of Translational medicine, Department of Biostatistics, Liverpool, UK

P094: Polyphenolic extract from Chilean berry attenuates intestinal damage and improves clinical indicators in an animal model of Crohn's disease

ECCO '19 Copenhagen

Year: 2019

Authors:

T. Ortiz*¹, J-M. García-Montes², F. Argüelles-Arias³, M. Illanes¹, M. Guerra Veloz³, M. Escoriza-Rodríguez¹, M. De Miguel¹

¹University of Seville, Normal and Pathological Cytology and Histology, Seville, Spain, ²University of Seville, Medicine, Seville, Spain, ³Virgen Macarena Hospital, Gastroenterology unit, Seville, Spain

P095: Association between tissue oncostatin M expression and infliximab response in corticosteroid refractory acute severe ulcerative colitis

ECCO '19 Copenhagen

Year: 2019

Authors:

J. O'Connell¹, P. McDonagh¹, N. Clarke², A. Buckley², C. Dunne^1,3, K. Hartery^1,3, J. Larkin⁴, F. MacCarthy^3,5, P. McCormack⁴, S. McKiernan^1,3, B. Mehigan⁴, C. Muldoon⁶, C. Ryan⁶, J. O'Sullivan², D. Kevans^1,3

¹St James's Hospital, Department of Gastroenterology, Dublin, Ireland, ²Trinity College Dublin, Dept of Surgery, Dublin, Ireland, ³INITIative, Investigator Network Inflammatory bowel disease Therapy in Ireland, Dublin, Ireland, ⁴St James Hospital, Surgery, Dublin, Ireland, ⁵St James's Hospital, Gastroenterology, Dublin, Ireland, ⁶St James Hospital, Pathology, Dublin, Ireland

P096: The anti-inflammatory effects of niclosamide on cytokines produced by PBMCs derived from IBD patients

ECCO '19 Copenhagen

Year: 2019

Authors:

U. N. Shivaji*^1,2, L. Jeffery¹, N. Batis³, M. Iacucci^1,2, S. Ghosh^1,2

¹National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Immunology and Immunotherapy, Birmingham, UK, ²Institute of Translational Medicine, Gastroenterology, Birmingham, UK, ³Institute of Cancer and Genomics Sciences, University of Birmingham, Birmingham, UK

P097: Intestinal barrier dysfunction in association with fibrosis during experimental acute and chronic colitis in mice

ECCO '19 Copenhagen

Year: 2019

Authors:

T. Breugelmans*¹, J. De Man¹, B. De Winter¹, A. Smet¹

¹University of Antwerp, Laboratory of Experimental Medicine and Pediatrics, Antwerp, Belgium

P098: Role of serum lysol oxidase like 2 in Crohn's disease and modulation to biological treatment

ECCO '19 Copenhagen

Year: 2019

Authors:

M. J. Garcia Garcia*¹, A. Garcia Blanco², B. Castro Senosiain¹, M. Pascual Mato¹, C. Del Pozo Calzada¹, J. Crespo Garcia¹, M. Rivero Tirado¹

¹Marques De Valdecilla Universitary Hospital, Gastroenterology, Santander, Spain, ²Biotechnology and Biomedicine Institute of Cantabria (IBBTEC), Santander, Spain

P099: Patients with ulcerative colitis show increased Treg number in peripheral blood after 1 year of anti-TNF therapy

ECCO '19 Copenhagen

Year: 2019

Authors:

D. Kyurkchiev*¹, E. Ivanova-Todorova¹, Z. Spasova², T. Velikova¹, M. Petkova², E. Krasimirova¹, K. Tumangelova - Yuzeir¹, L. Mateva - Vladimirova²

¹Laboratory of Clinical immunology, University hospital St. Ivan Rilski, Medical university of Sofia, Sofia, Bulgaria, ²Clinic of gastroenterology, University hospital ‘St. Ivan Rilski’, Department of Internal medicine, Medical University of Sofia, Bulgaria, Sofia, Bulgaria

P100: Real-world data: the incidence, diagnosis, and management outcomes of patients with immunotherapy-related colitis in two tertiary centres

ECCO '19 Copenhagen

Year: 2019

Authors:

V. Cheung*¹, T. Gupta¹, A. Olsson-Brown², S. Subramanian³, M. Payne⁴, M. Middleton⁴, O. Brain¹

¹Translational Gastroenterology Unit, Gastroenterology, Oxford, UK, ²Clatterbridge Cancer Centre, Oncology, Liverpool, UK, ³Royal Liverpool University Hospital, Gastroenterology, Liverpool, UK, ⁴Churchill Hospital, Oncology, Oxford, UK

P101: Simple five-point classification of MR enterocolonography for Crohn’s disease based on enteroscopic findings

ECCO '19 Copenhagen

Year: 2019

Authors:

T. Fujii*¹, Y. Kitazume², K. Takenaka¹, K. Suzuki¹, M. Motobayashi¹, E. Saito¹, M. Nagahori¹, K. Ohtsuka¹, M. Watanabe¹

¹Tokyo Medical and Dental University, Gastroenterology and Hepatology, Tokyo, Japan, ²Tokyo Medical and Dental University, Radiology, Tokyo, Japan

P102: Subclinical atherosclerosis assessed by coronary artery calcium score in patients with Crohn’s disease

ECCO '19 Copenhagen

Year: 2019

Authors:

B. Rocha*¹, C. Nomura², M. Rocha², B. Lopes², M. Azevedo¹, A. Carlos¹, F. Carrillo¹, A. Damiao¹, A. Sipahi¹, A. Leite¹

¹University of São Paulo Medical School, Department of Gastroenterology and Hepatology, São Paulo, Brazil, ²University of São Paulo Medical School, Cardiovascular Magnetic Resonance and Computed Tomography Sector, Heart Institute, InCor, São Paulo, Brazil

P103: Degradation and formation of type III, IV and V collagen are associated with disease activity, disease severity and disease extension in patients with ulcerative colitis

ECCO '19 Copenhagen

Year: 2019

Authors:

J. H. Mortensen*¹, V. Domislovic², M. A. Karsdal¹, M. Brinar², Z. Krznaric², T. Manon-Jensen¹

¹Nordic Bioscience, Biomarkers and Research, Herlev, Denmark, ²Clinical Hospital Centre Zagreb, Gastroenterology and Hepatology, Zagreb, Croatia

P104: Monitoring inflammatory activity in Crohn’s disease: simple ultrasonographic score vs. CEUS which one to use?

ECCO '19 Copenhagen

Year: 2019

Authors:

C. Arieira*^1,2,3, S. Monteiro^1,2,3, F. Dias de Castro^1,2,3, J. Magalhães^1,2,3, S. Leite^1,2,3, M. J. Moreira^1,2,3, J. Cotter^1,2,3

¹Hospital da Senhora da Oliveira, Gastroenterology, Guimarães, Portugal, ²Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga/Guimarães, Portugal, ³ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal

P105: Can patients enter the ‘Standard Set’ ICHOM parameters by completing electronic questionnaires?

ECCO '19 Copenhagen

Year: 2019

Authors:

A. Walsh*¹, R. Kantchuster¹, L. Matini¹, J. Wilson¹, M. Lepetyukh¹, R. Palmer¹, O. Brain¹, S. Keshav¹, S. Travis¹

¹John Radcliffe Hospital, Translational Gastroenterology Unit, Oxford, UK

P106: Successful outcome of the transitional process of inflammatory bowel disease from paediatric to adult age: a 5-year experience

ECCO '19 Copenhagen

Year: 2019

Authors:

A. Testa¹, O. M. Nardone*¹, E. Giannetti², A. Rispo¹, M. Rea¹, E. Scarpato², A. Opramolla¹, N. Imperatore¹, I. Di Luna¹, A. M. Staiano², F. Castiglione¹

¹Gastroenterology, School of Medicine Federico II of Naples, Naples, Italy, ²Pediatrics, School of Medicine Federico II of Naples, Naples, Italy

P107: Value of faecal biomarkers are affected by extension of inflammation in ulcerative colitis

ECCO '19 Copenhagen

Year: 2019

Authors:

N. Nemoto*¹, A. Sakuraba², R. Ozaki², T. Sato², S. Tokunaga², O. Kikuchi², S. Minowa², O. Ikezaki², T. Mitsui², M. Miura², D. Saito², M. Hayashida², M. Yoneyama³, H. Mori², H. Ohnishi⁴, T. Hisamatsu²

¹Kyorin University School of Medicine, Tokyo, Japan, ²Kyorin University School of Medicine, The Third Department of Internal Medicine, Tokyo, Japan, ³Kyorin University Hospital, Central Clinical Laboratory, Tokyo, Japan, ⁴Kyorin University School of Medicine, Department of Laboratory Medicine, Tokyo, Japan

P108: Validation of a new score for paediatric Crohn's disease on a paediatric tertiary hospital: the MINI-Index (Mucosal Inflammation Non-Invasive Index)

ECCO '19 Copenhagen

Year: 2019

Authors:

J. González Pérez¹, G. Pujol Muncunill*¹, V. Vila Miravet¹, J. Martin de Carpi¹

¹Hospital Sant Joan de Déu, Unit for Comprehensive Care of Pediatric Inflammatory Bowel Disease. Pediatric Gasatroneterology, Hepatology and Nutrition Unit, Barcelona, Spain

P109: Analysis of the clinical, gastroscopic, and pathological features of upper gastrointestinal lesions in Crohn’s disease

ECCO '19 Copenhagen

Year: 2019

Authors:

M. Li¹, Q. Yang¹, Z. Huang¹, J. Zhao¹, K. Cao¹, J. Tang¹, X. Fan², H. Chen³, Y. Huang², C. Li³, M. Zhi¹, P. Hu¹, X. Gao*¹

¹Department of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Department of Pathology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ³Department of Endoscopy, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

P110: Inter-rater validity of a new scoring index for Crohn’s disease (Crohn's disease activity in capsule endoscopy)

ECCO '19 Copenhagen

Year: 2019

Authors:

T. Omori*¹, K. Yasuhiro¹, S. Murasugi¹, H. Kambayashi¹, T. Hara¹, A. Ito¹, M. Yonezawa¹, S. Nakamura¹, K. Tokushige¹

¹Tokyo Women's Medical University, Institute of gastroenterology, Tokyo, Japan

P111: Clinical validation of a blood-based prognostic biomarker in Inflammatory bowel disease; towards personalised medicine in IBD

ECCO '19 Copenhagen

Year: 2019

Authors:

P. Lyons*¹

¹University of Cambridge, Department of Medicine, Cambridge, UK

P112: Long-term outcome of immunomodulators use in paediatric patients with inflammatory bowel disease

ECCO '19 Copenhagen

Year: 2019

Authors:

K. van Hoeve*^1,2, I. Hoffman¹, M. Ferrante^2,3, S. Vermeire^2,3

¹University Hospitals Leuven, Department of Paediatric gastroenterology and Hepatology and Nutrition, Leuven, Belgium, ²Catholic University of Leuven (KU Leuven), TARGID, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), Leuven, Belgium, ³University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium