¹"Dana-Dwek" Children's Hospital, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, The Pediatric Gastroenterology unit, Tel Aviv, Israel, ²Rabin Medical Center, Division of Gastroenterology, Petach Tikvah, Israel, ³Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁴"Dana-Dwek" Children's Hospital, Tel Aviv Sourasky Medical Center, Pediatric Sleep Center, Tel Aviv, Israel, ⁵The Hebrew University, Institute of Biochemistry, Food Science and Nutrition, Faculty of Agriculture, Food and Environment, Rehovot, Israel

¹University of Calgary, Gastroenterology, Calgary, Canada, ²Institute of Translational of Medicine, University of Birmingham, Birmingham, UK, ³Division of Gastroenterology, Baltimore, USA, ⁴Division of Gastroenterology IRCCS Policlinico San Donato, Milan, Italy, ⁵Division of Gastroenterology, Torino, Italy, ⁶Division of Gastroenterology, University Klinikum Tuebingen, Tuebingen, Germany, ⁷University of Calgary, Pathology, Calgary, Canada, ⁸Institute of Pathology ASST Ospedali Civili, Brescia, Italy, ⁹University of Calgary, Calgary, Canada, ¹⁰University of Leuven, Leuven, Belgium, ¹¹University John Hopkins, Baltimore, USA, ¹²University of Birmingham, Birmingham, UK, ¹³University of Portsmouth, Portsmouth, UK, ¹⁴Director of Internal Medicine II, HSK Hospital, Wiesbaden, Germany, ¹⁵Division of Gastroenterology, University Hospitals Leuven, Leuven, Belgium

¹McGill University Health Centre, Gastroenterology, Montreal, Canada, ²Division of Gastroenterology and Hepatology, Department of Medical Specialties, Geneva, Switzerland, ³Princess Alexandra Hospital, Department of Gastroenterology and Hepatology, Brisbane, Australia, ⁴La Tour Hospital and University of Geneva, Internal Medicine Department, Geneva, Switzerland, ⁵McGill University Health Center, Division of Gastroenterology, Epidemiology and Biostatistics and Occupational Health, Montreal, Canada, ⁶Semmelweis University, 1st Department of Medicine, Budapest, Hungary

¹University Hospital Zurich, Gastroenterology and Hepatology, Zurich, Switzerland, ²University Hospital Zurich, Division of Gastroenterology and Hepatology, Zurich, Switzerland, ³University of Lausanne, IUMSP, Lausanne, Switzerland, ⁴Klinik Hirslanden, Department of Gastroenterology, Zurich, Switzerland, ⁵Clinic Bethanien, Division of Gastroenterology and Hepatology, Zurich, Switzerland, ⁶University of Bern, Institute of Social and Preventive Medicine, Bern, Switzerland, ⁷University Hospital Lausanne, Division of Gastroenterology and Hepatology, Lausanne, Switzerland, ⁸Unilabs Switzerland, Medical Diagnostics, Duebendorf, Switzerland, ⁹Center of Gastroenterology and Hepatology, Zurich, Switzerland

¹"Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania, ²Institute of Gastroenterology and Hepatology, Bd. Independentei, no. 1, Gastroenterology and Hepatology, Iasi, Romania, ³"Gr. T. Popa" University of Medicine and Pharmacy, Institute of Gastroenterology and Hepatology, Iasi, Romania

¹Complejo Hospitalario Ferrol, Gastroenterology, Ferrol, Spain, ²Hospital Universitario Puerta De Hierro, Madrid, Spain, ³Hospital Universitari de Bellvitge, Barcelona, Spain, ⁴Hospital Marques de Valdecilla, Santander, Spain, ⁵Hospital de Poniente, Almería, Spain, ⁶Hospital Universitario La Fe, Valencia, Spain, ⁷Hospital Universitario de La Princesa, Madrid, Spain, ⁸Hospital San Pedro De Alcantara, Caceres, Spain, ⁹Hospital Doctor Negrín, Gran Canaria, Spain, ¹⁰Hospital Miguel Servet, Zaragoza, Spain, ¹¹Hospital Central de Asturias, Oviedo, Spain, ¹²Hospital General Universitario Gregorio Marañón, Madrid, Spain, ¹³Universidad de La Coruña, Coruña, Spain

¹University of Ulsan College of Medicine, Asan Medical Center, Department of Gastroenterology, Seoul, South Korea, ²University of Ulsan College of Medicine, Asan Medical Center, Inflammatory Bowel Disease Center, Seoul, South Korea

¹University of Duisburg-Essen, Integrative Gastroenterology, Kliniken Essen-Mitte, Essen, Germany, ²Tech Lab Inc., Blacksburg, USA, ³Labor L+S, Enterosan, Bad Bocklet-Grossenbrach, Germany, ⁴University of Duisburg-Essen, Integrative and Internal Medicine, Essen, Germany, ⁵University Hospital Essen, Institute of Diagnostic and Interventional Radiology and Neuroradiology, Essen, Germany

¹Kyungpook National University School of Medicine, Internal Medicine, Daegu, South Korea, ²Yeungnam University College of Medicine, Department of Internal Medicine, Daegu, South Korea, ³Keimyung University School Of Medicine, Department of Internal Medicine, Daegu, South Korea, ⁴Catholic University of Daegu, Department of Internal Medicine, Daegu, South Korea, ⁵Goo Hospital, Department of Surgery, Daegu, South Korea

¹Hospital Bonorino Udaondo, IBD Section - Medicine, Buenos Aires, Argentina, ²Hospital of Infectious Diseases F. J. Muñiz, Hemostasis and Thrombosis Laboratory, Buenos Aires, Argentina, ³Instituto de Farmacología, Facultad de Medicina Universidad de Buenos Aires, Buenos Aires, Argentina, ⁴Instituto de Medicina Experimental (IMEX), Academia Nacional de Medicina, Buenos Aires, Argentina, ⁵Yale University School of Medicine, Department of Immunobiology and Pharmacology, New Haven, USA

¹University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, ²KU Leuven, Department of Chronic Diseases, Metabolism and Ageing, Leuven, Belgium, ³Imeldaziekenhuis, Department of Gastroenterology and Hepatology, Bonheiden, Belgium, ⁴University Hospitals Leuven, Department of Laboratory Medicine, Leuven, Belgium

¹APHP Hôpital Saint Antoine, Gastro-entérologie et Nutrition, Paris, France, ²Hôpital Begin, Gastro-entérologie, Saint-Mandé, France

¹Azienda Ospedaliera Villa Sofia-Cervello, Emergency and General Surgery, Palermo, Italy, ²Maria Skłodowska-Curie Memorial Institute of Oncology Cancer Centre, Krakow, Poland

¹CHU Strasbourg, Department of Gastroenterology and Hepatology, Strasbourg, France, ²CHU Nancy, Department of Gastroenterology and Hepatology, Vandoeuvre-Lès-Nancy, France, ³CHRU Lille, Department of Gastroenterology, Lille, France, ⁴CHU Beaujon, Department of Gastroenterology, Clichy, France, ⁵CHU Saint-Antoine, Department of Gastroenterology, Paris, France, ⁶CHU Pontchaillou, Department of Gastroenterology, Rennes, France, ⁷CHU Nimes, Department of Gastroenterology and Hepatology, Nimes, France, ⁸CHU Bordeaux, Department of Gastroenterology, Bordeaux, France, ⁹CHU Bicêtre, Department of Gastroenterology, Le Kremlin-Bicêtre, France, ¹⁰CHU Montpellier Saint Eloi Hospital, Department of Gastroenterology, Montpellier, France, ¹¹CHU Liège, Sart Tilman, Department of Gastroenterology, Liège, Belgium, ¹²CHU Marseille, Department of Gastroenterology and Hepatology, Marseille, France, ¹³CHU Nantes, Department of Gastroenterology and Hepatology, Nantes, France, ¹⁴Hospital Edouard Herriot, Department of Gastroenterology and Hepatology, Lyon, France, ¹⁵Archet 2 Hospital, Department of Gastroenterology, Nice, France, ¹⁶Cochin Hospital, Department of Gastroenterology, Paris, France, ¹⁷Rouen Hospital, Department of Gastroenterology and Hepatology, Rouen, France, ¹⁸CHU Besancon, Department of Gastroenterology and Hepatology, Besançon, France, ¹⁹Hospital Cote de Nacre, Department of Gastroenterology, Caen Cede, France, ²⁰Amiens University Hospital, Department of Gastroenterology, Amiens, France, ²¹CHU Clermont-Ferrand, Department of Gastroenterology and Hepatology, Clermont Ferrand, France, ²²CHU Nancy, Department of Gastroenterology and Hepatology, Nancy, France, ²³CHU Strasbourg, Strasbourg, France, ²⁴Henri Mondor Hospital, Gastroenterology, Creteil, France

¹St Mark's Hospital, Colorectal Surgery, London, UK, ²St Mark's Hospital, Gastrointestinal Imaging, London, UK, ³St Mark's Hospital, IBD/Physiology, London, UK

¹Assaf Harofeh Medical Center, The Kamila Gonczarowski institute of Gastroenterology Assaf Harofeh Medical Center, Zerifin, Israel, ²Tel Aviv university Sackler school of medicin, internal medicine, Tel aviv, Israel, ³Tel Aviv university Sackler school of medicin, internal medicine, Tel Aviv, Israel

¹Rabin Medical Center, Beilinson Hospital, Department of Gastroenterology, Petah Tikva, Israel, ²Tel Aviv University, Sackler Faculty of Medicine, Tel Aviv, Israel, ³Tel Aviv Sourasky Medical Center, Genetic Institute, Tel Aviv, Israel, ⁴Tel Aviv Sourasky Medical Center, Department of Gastroenterology and Liver Diseases, Tel Aviv, Israel, ⁵Tel Aviv University, Israel, Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv, Israel

¹Humanitas Clinical and Research Institute, Rozzano, Italy, ²University of Nancy, Nancy, France

¹Medical University of Vienna, Department of Internal Medicine III, Vienna, Austria, ²Hospital Barmherzige Brüder St. Veit an der Glan, Department of Internal Medicine, St. Veit an der Glan, Austria, ³Darmpraxis Salzburg, Salzburg, Austria, ⁴Medical University of Graz, Department of Gastroenterology and Hepatology, Graz, Austria, ⁵Hospital Wels-Grieskirchen, Department of Internal Medicine I, Wels, Austria, ⁶Medical University of Innsbruck, Department of Internal Medicine I, Innsbruck, Austria, ⁷Hospital Rudolfstiftung, Department of Internal Medicine IV, Vienna, Austria, ⁸Hospital Oberpullendorf, Department of Internal Medicine, Oberpullendorf, Austria, ⁹Universitätsklinikum St. Pölten, Department of Internal Medicine II, St. Pölten, Austria, ¹⁰Hospital Wels-Grieskirchen, Department of Internal Medicine V, Grieskirchen, Austria, ¹¹Hospital Hall in Tirol, Department of Internal Medicine, Hall in Tirol, Austria, ¹²Hospital Wiener Neustadt, Department of Internal Medicine I, Wiener Neustadt, Austria, ¹³Hartmannspital, Department of Internal Medicine, Vienna, Austria, ¹⁴Hanusch Hospital, Department of Internal Medicine, Vienna, Austria, ¹⁵Hospital Elisabethinen Linz, Department of Internal Medicine IV, Linz, Austria, ¹⁶Hospital Barmherzige Brüder Salzburg, Department of Internal Medicine, Salzburg, Austria, ¹⁷Hospital Feldkirch, Department of Internal Medicine, Feldkirch, Austria, ¹⁸Hospital Barmherzige Brüder Graz, Department of Internal Medicine, Graz, Austria, ¹⁹Medical University of Vienna, Department of Epidemiology, Vienna, Austria

¹University of Ulsan College of Medicine, Asan Medical Center, Department of Gastroenterology, Seoul, South Korea, ²University of Ulsan College of Medicine, Asan Medical Center, Department of Clinical Epidemiology and Biostatistics, Seoul, South Korea, ³University of Ulsan College of Medicine, Asan Medical Center, Inflammatory Bowel Disease Center, Seoul, South Korea