¹University of Messina, Department of Clinical and Experimental Medicine, Messina, Italy, ²University of Messina, Department of Economics, Messina, Italy

¹University of Alberta, Biological Sciences and Psychology, Edmonton, Canada, ²University of Alberta, Zeidler Ledcor Center, Department of Gastroenterology, Edmonton, Canada, ³University of Alberta, Zeidler Ledcor Centre, Department of Gastroenterology, Edmonton, Canada, ⁴University of Alberta, Department of Medicine, Edmonton, Canada

¹Centro Hospitalar Vila Nova de Gaia/Espinho, Gastroenterology and Hepatology, Vila Nova de Gaia, Portugal, ²Centro Hospitalar São João, Psychiatry, Porto, Portugal

¹Reina Sofia University Hospital, Gastroenterology, Córdoba, Spain, ²Reina Sofia University Hospital, Nuclear Medicine, Córdoba, Spain, ³Instituto Maimónides de Investigación Biomédica de Córdoba, Córdoba, Spain

¹Logan Hospital, Gastroenterology department, Meadowbrook, Australia, ²Queen Elizabeth II Hospital, Colorectal Surgery, Coopers Plains, Australia

Chaim Sheba Medical Center, Gastroenterology, Ramat Gan, Israel

¹Hospital Universitari Mutua Terrassa, Gastroenterology, Terrassa, Spain, ²CIBERehd, Terrassa, Spain

Hospital University of Sahloul, Gastroenterology, Sousse, Tunisia

¹Seoul National University Bundang Hospital, Internal medicine, Seongnam, South Korea, ²Seoul National University College of Medicine, Internal Medicine and Liver Research Institute, Seoul, South Korea

¹University Hospital Zurich, Division of Gastroenterology and Hepatology, Zurich, Switzerland, ²University of Lausanne, IUMSP, Lausanne, Switzerland, ³Klinik Hirslanden, Department of Gastroenterology, Zurich, Switzerland, ⁴University of Bern, Institute of Social and Preventive Medicine, Bern, Switzerland, ⁵CHUV - Centre Hospitalier Universitaire Vaudois, Department of Gastroenterology, Lausanne, Switzerland, ⁶Hospital Triemli, Gastroenterology and Hepatology, Zurich, Switzerland, ⁷University Hospital Zurich, Gastroenterology and Hepatology, Zurich, Switzerland

¹University Hospital Estaing, Gastroenterology Department, Clermont-Ferrand, France, ²UMR 1071 Inserm/Université d'Auvergne; USC-INRA 2018, Microbes, Intestine, Inflammation and Susceptibility of the Host, Clermont-Ferrand, France, ³Queen Elizabeth Hospital, Department of Medicine, Hong Kong, Hong Kong, ⁴Inflammatory Bowel Disease Center University of Chicago Medicine, Chicago, USA, ⁵University Hospital, Biostatistics Unit, DRCI, Clermont-Ferrand, France

¹Hospital Clinic Barcelona, Gastroenterology, CIBERehd, IDIBAPS, University of Barcelona, Barcelona, Spain, ²University Hospital Clinic de Barcelona, Department of Radiology, CIBER-EHD, IDIBAPS, Barcelona, Spain

¹University of California, San Diego, Division of Gastroenterology, La Jolla, USA, ²Robarts Clinical Trials, La Jolla, USA, ³University of California, Division of Gastroenterology, La Jolla, USA, ⁴Prometheus Laboratories Inc., La Jolla, USA

¹Ospedale Sacro Cuore Don Calabria, IBD Unit, Negrar, Italy, ²Ospedale Sacro Cuore Don Calabria, Radiology, Negrar, Italy

¹Catholic University of Sacred Heart, Internal Medicine Department, Gastroenterology Division, Rome, Italy, ²Case Western Reserve University, Pathology, Cleveland, USA

Yokkaichi Hazu Medical Centre, Inflammatory Bowel Disease Centre, Yokkaichi, Japan

¹The Ohio State University – Wexner Medical Center, Columbus, USA, ²Truven Health Analytics, an IBM Company, Cambridge, USA, ³AbbVie Inc., North Chicago, USA

¹Policlinico San Martino, University of Genoa, Department of Internal Medicine, Genoa, Italy, ²Prometheus Laboratories, Department of Research and Development, San Diego, California, USA, ³University of Padua, Department of Surgery, Oncology and Gastroenterology, Padova, Italy

¹Faculty of Medicine, University of Porto,, Department of Biomedicine, Unit of Pharmacology and Therapeutics, Porto, Portugal, ²Centro Hospitalar São João, Gastroenterology Department, Porto, Portugal, ³Centre for Drug Discovery and Innovative Medicines, University of Porto, Porto, Portugal, ⁴Faculty of Medicine, Centro Hospitalar Sao Joao, Department of Pathology, Porto, Portugal, ⁵Faculty of Medicine, University of Lisbon, Institute of Pathology, Lisbon, Portugal, ⁶Centro Hospitalar São Joao, Department of Gastroenterology, Porto, Portugal, ⁷Hospital da Senhora da Oliveira, Department of Gastroenterology, Guimarães, Portugal, ⁸Centro Hospitalar do Algarve, Gastroenterology Department, Portimão, Portugal, ⁹Centro Hospitalar do Porto, Department of Gastroenterology, Porto, Portugal, ¹⁰Hospital Garcia de Orta, Department of Gastroenterology, Almada, Portugal, ¹¹Centro Hospitalar do Algarve, Department of Gastroenterology, Faro, Portugal, ¹²Divino Espírito Santo Hospital, Department of Gastroenterology, Ponta Delgada, Portugal, ¹³Instituto Português do Oncologia de Lisboa, Department of Gastroenterology, Lisboa, Portugal, ¹⁴Centro hospitalar e Universitário de Coimbra, Department of Gastroenterology, Coimbra, Portugal, ¹⁵Centro Hospitalar Tondela-Viseu, Department of Gastroenterology, Viseu, Portugal, ¹⁶Hospital de Braga, Department of Gastroenterology, Braga, Portugal, ¹⁷Hospital Fernando da Fonseca, Department of Gastroenterology, Amadora, Portugal, ¹⁸Instituto Português de Oncologia de Lisboa,, Gastroenterology Department, Lisboa, Portugal, ¹⁹Centro Hospitalar Lisboa Ocidental, Department of Gastroenterology, Lisbon, Portugal, ²⁰Hospital Beatriz Angelo, Department of Gastroenterology, Loures, Portugal, ²¹Faculty of Medicine, University of Porto, Health Information and Decision Sciences Department, Porto, Portugal, ²²Center for Health Technology and Services Research, Porto, Portugal, ²³University Hospital of KU Leuven and UZ Gent, Department of Pathology, Leuven, Belgium, ²⁴Instituto de Investigação e Inovação na Saúde (I3S), Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal

¹Kyungpook National University Hospital, Kyungpook National University School of Medicine, Division of Gastroenterology, Department of Internal Medicine, Daegu, South Korea, ²Kyungpook National University Medical Center, Kyungpook National University School of Medicine, Division of Gastroenterology, Department of Internal Medicine, Daegu, South Korea