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P816 Association of autoimmune rheumatic disease with inflammatory bowel disease: a nationwide population-based study

ECCO'20 Vienna

Year: 2020
Authors:

D. Baek1, H.S. Lee2, S.B. Park3, H.K. Song4, B.I. Jang5, J.H. Bae6, H.J. Goong7, H.S. Kang8, S.H. Jung9, T.O. Kim10, G.A. Song1, E.Y. Park1

1Pusan National University School of Medicine & Pusan National University Hospital, Internal Medicine, Busan, Republic of Korea, 2Inje University Busan Paik Hospital, Internal Medicine, Busan, Republic of Korea, 3Pusan National University Yangsan Hospital, Internal Medicine, Yangsan, Republic of Korea, 4Ewha Womans University College of Medicine, Internal Medicine, Seoul, Republic of Korea, 5Yeungnam University College of Medicine, Internal Medicine, Daegu, Republic of Korea, 6Healthcare System Gangnam Center, Seoul National University Hospital, Internal Medicine, Seoul, Republic of Korea, 7Soonchunhyang University Bucheon Hospital, Gastroenterology and Hepatology, Bucheon, Republic of Korea, 8Hallym University Sacred Heart Hospital, Internal Medicine-, Anyang, Republic of Korea, 9The Catholic University of Korea, Internal Medicine, Seoul, Republic of Korea, 10Inje university Haeundae Paik Hospital, Internal Medicine, Busan, Republic of Korea

P817 Influence of inflammatory bowel diseases on depression and suicidal risk: a questionnaire-based survey

ECCO'20 Vienna

Year: 2020
Authors:

T. Molnár1, P. Miheller2, P. Sarlós3, A. Sánta1, A. Juhász2, E. Hamvas4, T. Nyári5, K.J. Szántó1, R. Bor1, A. Fábián1, A. Bálint1, Á. Milassin1, M. Rutka1, Z. Szepes1, K. Farkas1

1University of Szeged, First Department of Medicine, Szeged, Hungary, 2University of Semmelweis, First Department of Surgery, Budapest, Hungary, 3University of Pécs, First Department of Medicine, Pécs, Hungary, 4University of Pécs, Department of Psychiatry and Psychotherapy, Pécs, Hungary, 5University of Szeged, Department of Medical Physics and Informatics, Szeged, Hungary

P818 Venous thromboembolism is rare among hospitalised patients with an inflammatory bowel disease flare: a multicentre retrospective cross-sectional study

ECCO'20 Vienna

Year: 2020
Authors:

T. Khoury1, A. Shafrir2, I. Kalisky2, M. Safadi3, A. Mari3, M. Mahamid3, L. H Katz2, A. Kadah1, W. Sbeit1

1Department of Gastroenterology, Galilee Medical Center, Bar Ilan University, Safed- Israel, Naharia, Israel, 2Hadassah Medical Organization, Department of Gastroenterology and liver disease, Jerusalem, Israel, 3EMMS Nazreth Hospital, Gastroenterology and Endoscopy Units, Nazareth, Israel

P819 Seroprevalence of Borrelia burgdorferi antibodies in patients with ulcerative colitis

ECCO'20 Vienna

Year: 2020
Authors:

A.C. Dulger

Lefkoşa State Hopital Education and Research Hospital, Gastroenterology, Lefkoşa/Turkish side, Cyprus

P820 An easy and rapid targeted next generation sequencing-based genotyping assay for the validated IBD risk loci

ECCO'20 Vienna

Year: 2020
Authors:

S. Verstockt1, L. Hannes2, S. Deman2, W.J. Wollants1, E. Souche2, B. Verstockt1, I. van der Werf3, A. Hoischen4, M. Ferrante1, S. Vermeire1, I. Cleynen2

1Department of Chronic Diseases- Metabolism and Ageing, KU Leuven, Leuven, Belgium, 2Department of Human Genetics, KU Leuven, Leuven, Belgium, 3University of Antwerp, Department of Biomedical sciences, Antwerp, Belgium, 4Radboud University Medical Center, Department of Human Genetics, Nijmegen, The Netherlands

P821 HLADQA1-HLADRB1 pre-emptive screening for azathioprine-induced pancreatitis in inflammatory bowel disease: a preliminary report

ECCO'20 Vienna

Year: 2020
Authors:

A. Wilson1, Q. Wang2, J. Gregor1, N. Chande1, M. Beaton1, T. Ponich1, M. Sey1, B. Yan1, R. Kim1

1London Health Sciences Centre, Medicine, London, Canada, 2Western University, Medicine, London, Canada

P822 Genetic analysis of ulcerative colitis in Japanese individuals using population-specific SNP array

ECCO'20 Vienna

Year: 2020
Authors:

D. Okamoto1, Y. Kakuta1, N. Takeo1, R. Moroi1, M. Kuroha1, Y. Kanazawa1, S. Hisashi1, Y. Fuyuno2, J. Umeno2, A. Hirano2, T. Torisu2, M. Nakamura3, M. Esaki4, T. Matsumoto5, Y. Kinouchi1, A. Masamune1

1Tohoku University Graduate School of Medicine, Division of Gastroenterology, Sendai, Japan, 2Graduate School of Medical Sciences- Kyusyu University, Department of Medicine and Clinical Science, Fukuoka, Japan, 3National hospital organization NHO Nagasaki Medical Center, Clinical Research Center, Omura, Japan, 4Saga University, Department of Endoscopic Diagnostics and Therapeutics, Saga, Japan, 5Iwate Medical University, Division of Gastroenterology- Department of Internal Medicine- Faculty of Medicine, Morioka, Japan

P823 DNA methylation profiles accurately predict vedolizumab response and remain stable during induction and maintenance treatment in Crohn’s disease

ECCO'20 Vienna

Year: 2020
Authors:

V. Joustra1, I. Hageman2, A. Li Yim3, K. Gecse1, M. Lowenberg1, A. te Velde2, J. Satsangi4, W. de Jonge2, P. Henneman3, G. D’Haens1

1Amsterdam UMC location AMC, Gastroenterology and Hepatology, Amsterdam, The Netherlands, 2Tytgat Institute for Liver and Intestinal Research- Amsterdam UMC, Gastroenterology, Amsterdam, The Netherlands, 3Genome Diagnostics Laboratory- Amsterdam UMC location AMC, Clinical Genetics, Amsterdam, The Netherlands, 4John Radcliffe Hospital, Translational Gastroenterology Unit, Oxford, UK

P824 Molecular predictors of anti-TNF treatment response in patients with Crohn’s disease

ECCO'20 Vienna

Year: 2020
Authors:

M. WALCZAK1, L. Lykowska-Szuber2, M. Plucinska3, M. Michalak4, I. Krela-Kazmierczak2, O. Zakerska-Banaszak1, K. Stawczyk-Eder2, P. Eder2, A. Dobrowolska2, R. Slomski1, M. Skrzypczak-Zielinska1

1Institute of Human Genetics- Polish Academy of Sciences, Department of Nucleic Acid Function, Poznan, Poland, 2Poznan University of Medical Sciences, Department of Gastroenterology- Dietetics and Internal Diseases, Poznan, Poland, 3Institute of Molecular Biology and Biotechnology- Faculty of Biology- Adam Mickiewicz University, Department of Computational Biology, Poznan, Poland, 4Poznan University of Medical Sciences, Department of Computer Sciences and Statistics, Poznan, Poland

P825 The impact of a SNP-dose–response effect on course of inflammatory bowel disease: a numerical analysis of SNP distribution within the Swiss IBD Cohort Study

ECCO'20 Vienna

Year: 2020
Authors:

L. Biedermann1, L. Denoth1, J.B. Rossel2, M. Butter1, S. Vavricka3, B. Misselwitz4, T. Greuter1, P. Schreiner1, I. Cleynen5, G. Rogler1, M. Scharl1

1University Hospital Zurich, Gastroenterology and Hepatology, Zurich, Switzerland, 2University of Lausanne, Center for Primary Care and Public Health Unisanté, Lausanne, Switzerland, 3Private Practice, Center for Gastroenterology and Hepatology, Zurich, Switzerland, 4Inselspital Bern, Gastroenterology and Hepatology, Bern, Switzerland, 5KU Leuven- Leuven- Belgium, Department of Human Genetics, Leuven, Belgium

P826 A predictive molecular classification developed in UC patients with active disease is observed consistently in a heterogeneous group of IBD patients

ECCO'20 Vienna

Year: 2020
Authors:

K. Kulmala1, O.E. Diaz1, S. Huber2, C. Hedin3, E.J. Villablanca1

1Division of Immunology and Allergy, Department of Medicine- Solna- Karolinska Institutet and University Hospital- 17176 Stockholm- Sweden. Center of Molecular Medicine- 17176, Stockholm, Sweden, 2Department of Medicine, University Medical Center, Hamburg-Eppendorf, Germany, 3Gastroenterology unit- Patient Area Gastroenterology- Dermatovenereology and Rheumatology- Karolinska University Hospital- Stockholm- Sweden, Department of Medicine- Solna- Karolinska Institutet- 17176, Solna, Sweden

P827 The clinical phenotype of collagenous colitis is associated with T-cell-related genetic variants

ECCO'20 Vienna

Year: 2020
Authors:

G. Roda1, D. Piovani2, J. Prantesh3, I. Gordon3, R. Asselta4, S. Duga4, S. Vetrano1, S. Bonovas2, N. Harpaz5, S. Danese1, I. Peter6, J.F. Colombel7, F. Rieder3

1Humanitas Research Hospital, IBD Center, Milano, Italy, 2Humanitas Research Hospital, IBD Center/Department of Biomedical Sciences, Milano, Italy, 3Cleveland Clinic, Department of Gastroenterology, Cleveland, USA, 4Humanitas Research Hospital, Dept. Biomed. Sciences, Milano, Italy, 5Icahn School of Medicine at Sinai, Department of Pathology, New York, USA, 6Icahn School of Medicine at Sinai, Division of Genetics and Genomic Sciences, New York, USA, 7Icahn School of Medicine at Sinai, The Henry D. Janowitz Division of Gastroenterology, New York, USA

P828 DNA methylation profile defines epigenetic characteristics and molecular targets of Crohn’s disease

ECCO'20 Vienna

Year: 2020
Authors:

T.O. Kim1, J. Yi2, S.H. Jung3, D.H. Baek4, H.S. Lee5

1Inje University Haeundae Paik Hospital, Department of Internal Medicine, Busan, Republic of Korea, 2Inje University College of Medicine, Department of Microbiology and Immunology, Busan, Republic of Korea, 3Eunpyeong St. Mary’s Hospital- College of Medicine- The Catholic University of Korea, Department of Internal Medicine-, Seoul, Republic of Korea, 4Pusan National University School of Medicine and Biomedical Research Institute- Pusan National University Hospital, Department of Internal Medicine, Busan, Republic of Korea, 5Inje University Busan Paik Hospital, Inje University College of Medicine, Busan, Korea, Department of Internal Medicine, Busan, Republic of Korea

P829 Methylation patterns in dysplasia in inflammatory bowel disease patients

ECCO'20 Vienna

Year: 2020
Authors:

I.A. da Luz Rosa1, P. Silva2, S. Mata3, F. Magro4, F. Carneiro5, A. Peixoto4, M. Silva4, H. Sousa6, J. Roseira6, J. Parra7, R. Barosa8, A. Vieira8, M.J. Brito9, P. Lago10, A. Coelho11, J. Moleiro1, J. Silva1, R. Fonseca3, C. Albuquerque2, A.D. Pereira1

1Grupo de Estudos em Doença Inflamatória Intestinal, 1Instituto Português de Oncologia de Lisboa, Gastroenterology, Lisbon, Portugal, 2Instituto Português de Oncologia de Lisboa, Molecular Pathobiology Investigation Unit, Lisbon, Portugal, 3Instituto Português de Oncologia de Lisboa, Pathology, Lisbon, Portugal, 4Centro Hospitalar de São João, Gastroenterology, Porto, Portugal, 5Centro Hospitalar de São João, Pathology, Porto, Portugal, 6Centro Hospitalar Universitário do Algarve- Unidade de Portimão, Gastroenterology, Portimão, Portugal, 7Centro Hospitalar Universitário do Algarve- Unidade de Portimão, Pathology, Portimão, Portugal, 8Hospital Garcia de Orta, Gastroenterology, Almada, Portugal, 9Hospital Garcia de Orta, Pathology, Almada, Portugal, 10Centro Hospitalar do Porto- EPE–Hospital de Santo António, Gastroenterology, Porto, Portugal, 11Centro Hospitalar do Porto- EPE–Hospital de Santo António, Pathology, Porto, Portugal

P830 Genotype-based treatment with thiopurine reduces incidence of myelosuppression in patients with inflammatory bowel diseases

ECCO'20 Vienna

Year: 2020
Authors:

J.Y. Chang1, S.J. Park2, E.S. Jung3, S.A. Jung4, C.M. Moon5, J. Chun2, J.J. Park2, E.S. Kim6, Y. Park2, T.I. Kim2, W.H. Kim2, J.H. Cheon2

1College of Medicine- Ewha Womans University, Health Promotion Center, Seoul, Republic of Korea, 2Yonsei University College of Medicine, Internal Medicine, Seoul, Republic of Korea, 3Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea, 4Internal Medicine, College of Medicine- Ewha Womans University, Seoul, Republic of Korea, 5College of Medicine- Ewha Womans University, Internal Medicine, Seoul, Republic of Korea, 6Korea University College of Medicine, Internal Medicine, Seoul, Republic of Korea

P831 The role of adherent-invasive E. coli in pediatric Crohn’s disease: cause or effect?

ECCO'20 Vienna

Year: 2020
Authors:

N. Faqerah, Michael. Logan, Richard. Russell, Konstantinos. Gerasimidis, Daniel. Walker

University of Glasgow, Bacteriology, Glasgow, UK

P832 Gastrointestinal infections are associated with unique gut microbiome signatures in patients with inflammatory bowel disease

ECCO'20 Vienna

Year: 2020
Authors:

J. Axelrad1, A. Hine2, J. Devlin2, P. Loke2, K. Cadwell2

1New York University School of Medicine, Gastroenterology, New York, USA, 2New York University School of Medicine, Microbiology, New York, USA

P833 Bacterial mucosa-associated microbiome in inflamed and proximal non-inflamed ileum of patients with Crohn’s disease

ECCO'20 Vienna

Year: 2020
Authors:

M. Olaisen1,2, A. Flatberg1, A. van Beelen Granlund1,3, E.S. Røyset1,4, T.C. Martinsen1,2, A.K. Sandvik1,2,3, R. Fossmark1,2

1Department of Clinical and Molecular Medicine- Faculty of Medicine and Health Science, NTNU - Norwegian University of Sciences and Technology, Trondheim, Norway, 2Department of Gastroenterology, St. Olav’s Hospital- Trondheim University Hospital, Trondheim, Norway, 3Centre of Molecular Inflammation Research, NTNU - Norwegian University of Sciences and Technology, Trondheim, Norway, 4Department of Pathology, St. Olav’s Hospital- Trondheim University Hospital, Trondheim, Norway

P834 Effects of short-chain fatty acids supplementation on gut inflammation in DSS-induced murine colitis model

ECCO'20 Vienna

Year: 2020
Authors:

C.S. Eun, D.S. Han, J.G. Lee, C.H. Park

Department of Internal Medicine, Hanyang University Guri Hospital, Guri, Republic of Korea

P835 Correlation between microbial markers and faecal calprotectin in IBD patients

ECCO'20 Vienna

Year: 2020
Authors:

J. Amoedo Cibeira1,2, S. Ramió-Pujol1, M. Serra-Pagès3, A. Bahí4, C. Puig-Amiel4, L. Oliver1, P. Gilabert5, A. Clos6, M. Mañosa6, F. Cañete6, J.O. Miquel-Cusachs7, L. Torrealba7, D. Busquets7, M. Sàbat8, E. Domènech6, J. Guardiola5, J. Garcia-Gil1,2, X. Aldeguer1,4,7

1GoodGut SL, IBD Department, Girona, Spain, 2University of Girona, Department of Biology, Girona, Spain, 3GoodGut SL, Chief Executive Officer, Girona, Spain, 4Institut d’Investigació Biomèdica de Girona, Digestiu, Girona, Spain, 5Hospital Universitari de Bellvitge, Aparell Digestiu, Hospitalet de Llobregat, Spain, 6Hospital Universitari Germans Trias i Pujol de Badalona, Aparell Digestiu, Badalona, Spain, 7Hospital Universitari Doctor Josep Trueta de Girona, Aparell Digestiu, Girona, Spain, 8Hospital de Santa Caterina, Aparell Digestiu, Salt, Spain