P0478: Peripheral blood cytokines in patients with paediatric-onset Inflammatory Bowel Disease – a systematic review and meta-analysisECCO'25Year: 2025
Authors: Jansson, S.(1,2)*;Ehrström, A.(1,2);Rask, C.U.(3,4);Burisch, J.(2,5,6);Benros, M.E.(6,7);Seidelin, J.(6,8);Malham, M.(1,2,9,10);Wewer, V.(1,2,6);
(1)Amager and Hvidovre Hospital- University of Copenhagen, Department of Paediatrics and Adolescent Medicine, Hvidovre, Denmark;(2)Amager and Hvidovre Hospital- University of Copenhagen, Copenhagen Center for Inflammatory Bowel Disease in Children- Adolescents- and Adults, Hvidovre, Denmark;(3)Aarhus University Hospital Psychiatry, Department of Child and Adolescent Psychiatry, Aarhus, Denmark;(4)Aarhus University, Department of Clinical Medicine, Aarhus, Denmark;(5)Amager and Hvidovre Hospital- University of Copenhagen, Gastro Unit, Hvidovre, Denmark;(6)University of Copenhagen, Department of Clinical Medicine, Copenhagen, Denmark;(7)Mental Health Centre Copenhagen- Copenhagen University Hospital, Copenhagen Research Centre for Biological and Precision Psychiatry, Copenhagen, Denmark;(8)Rigshospitalet- University of Copenhagen, Department of Digestive Diseases- Transplantation- and General Surgery- IBD section, Copenhagen, Denmark;(9)Copenhagen Health Complexity Center- University of Copenhagen, Department of Public Health, Copenhagen, Denmark;(10)Royal Hospital for Children and Young People, Department of Paediatric Gastroenterology and Nutrition, Edinburgh, United Kingdom;
1) Neurath MF. Cytokines in inflammatory bowel disease. Nat Rev Immunol. 2014;14(5):329-342. doi:10.1038/nri3661
2) Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. Published 2021 Mar 29. doi:10.1136/bmj.n71
P0479: The impact of inflammatory bowel disease on sexuality of male and female patients.ECCO'25Year: 2025
Authors: Szymanska, E.(1)*;Kisielewska, L.(2);kotkowicz-szczur, M.(3);Kisielewski, R.(2);Jaroslaw, K.(4);
(1)Children's Memorial Health Institute, Department of Gastroenterology- Hepatology- Feeding Disorders and Pediatrics, Warsaw, Poland;(2)The Centre of Oncology- Bialystok- Poland, Department of Gynecologic Oncology, Bialystok, Poland;(3)The Children's Memorial Health Institute- Warsaw- Poland, Department of Gastroenterology- Hepatology- Feeding Disorders and Paediatrics, Warsaw, Poland;(4)The Children's Memorial Health Institute- Warsaw- Poland, Department of Gastroenterology- Hepatology- Feeding Disorders and Paediatrics., Warsaw, Poland;
P0480: Evaluating the risk factors of surgery and postoperative complications in stricturing Crohn's DiseaseECCO'25Year: 2025
Authors: Yunusov, E.(1);Piyade, B.(2);Ergenc, I.(3);Tasci, M.E.(4);Sariyar, N.(1);Ozen Alahdab, Y.(3);Atug, O.(3);Kani, H.T.(5)*;
(1)Marmara University School of Medicine, Internal Medicine, Istanbul, Turkey;(2)Marmara University School of Medicine, Internal Medicine, İstanbul, Turkey;(3)Marmara University School of Medicine, Gastroenterology, Istanbul, Turkey;(4)Marmara University, School of Medicine, Istanbul, Turkey;(5)Marmara University- School of Medicine, Gastroenterology, Istanbul, Turkey;
1- Bossuyt P, Debeuckelaere C, Ferrante M, de Buck van Overstraeten A, Vanbeckevoort D, Billiet T, Wolthuis A, Cleynen I, Van Assche G, D'Hoore A, Vermeire S. Risk Stratification for Surgery in Stricturing Ileal Crohn's Disease: The BACARDI Risk Model. J Crohns Colitis. 2018 Jan 5;12(1):32-38.
2- Celentano V, Giglio MC, Pellino G, Rottoli M, Sampietro G, Spinelli A, Selvaggi F; Italian Society of Colorectal Surgery SICCR. High complication rate in Crohn's disease surgery following percutaneous drainage of intra-abdominal abscess: a multicentre study. Int J Colorectal Dis. 2022 Jun;37(6):1421-1428.
P0481: Real-World Analysis of Disease Progression in Ulcerative Colitis: A Comparative Study Across Diagnostic Eras at a Tertiary IBD CenterECCO'25Year: 2025
Authors: Valdivia Krag, C.(1);Mirabent, C.(1);González Castilla, M.L.(1);Benítez, J.M.(1);Marín Pedrosa, S.(1);Soto, P.(1);Iglesias-Flores, E.(1);Gros, B.(2)*;
(1)Reina Sofía University Hospital, Gastroenterology and Hepatology, Cordoba, Spain;(2)Reina Sofía University Hospital. IMIBIC. University of Cordoba, Department of Gastroenterology, Córdoba, Spain;
P0483: Assessment of Disease Activity in Pediatric Inflammatory Bowel Disease Using Intestinal Ultrasound: A Comparative Diagnostic AnalysisECCO'25Year: 2025
Authors: Massironi , S.(1)*;Mulinacci , G.(2);Zuin , G.(3);Pirola , L.(4);Medici , F.(5);Carzaniga , V.(5);Zucchini , N.(6);Dinelli , M.E.(2);Maino , M.(2);
(1)Vita e Salute San Raffaele University, Istituti Ospedalieri Bergamaschi, Milan, Italy;(2)IRCCS Fondazione San Gerardo dei Tintori, Endoscopy, Monza, Italy;(3)IRCCS Fondazione San Gerardo dei Tintori, Pediatrics, Monza, Italy;(4)IRCCS Fondazione San Gerardo dei Tintori, Gastroenterology, Monza, Italy;(5)School of Medicine and Surgery - University Milano Bicocca, Pediatrics, Monza, Italy;(6)IRCCS Fondazione San Gerardo dei Tintori, Pathology, Monza, Italy;
1. van Wassenaer EA, van Rijn RR, Zwetsloot SLM, et al. Intestinal Ultrasound to Assess Ulcerative Colitis Disease Activity in Children: External Validation and Comparison of 2 Intestinal Ultrasound Activity Indices. Inflamm Bowel Dis. 2023;29:1217-1222.
2. Allocca M, Dell'Avalle C, Craviotto V, et al. Predictive value of Milan ultrasound criteria in ulcerative colitis: A prospective observational cohort study. United European Gastroenterol J. 2022;10:190-197.
3. Novak K.L., Nylund K., Maaser C., et al. Expert consensus on optimal acquisition and development of the international bowel ultrasound segmental activity score [IBUS-SAS]: a reliability and inter-rater variability study on intestinal ultrasonography in Crohn's disease. J Crohns Colitis. 2021;15:609–616.
P0484: Impact of Early Aggressive Treatment on Long-term Biochemical Marker Patterns in Inflammatory Bowel Disease: A latent class mixed modelECCO'25Year: 2025
Authors: Jun, Y.K.(1)*;Choi, Y.(1);Shin, C.M.(1);Park, Y.S.(1);Kim, N.(1);Lee, D.H.(1);Ahn, S.(2);Yoon, H.(1);
(1)Seoul National University Bundang Hospital, Department of Internal Medicine, Seongnam- Gyeonggi-do, Korea- Republic Of;(2)Seoul National University Bundang Hospital, Medical Research Collaborating Center, Seongnam- Gyeonggi-do, Korea- Republic Of;
P0485: Seroproteomic index of endoscopic activity associates with endoscopic outcomes in a longitudinal cohort of adults ulcerative colitisECCO'25Year: 2025
Authors: Boland, B.(1);Zablan, K.(1);Penrose, H.(1);Neill, J.(1);Le, H.(1);Ho, J.(2);Dervieux, T.(2)*;
(1)University of California San Diego, Gastroenterology, San Diego, United States;(2)Prometheus Laboratories, Research and Development, San Diego, United States;
P0486: Acceptability of fecal calprotectin in patients with inflammatory bowel disease: impact of an alternative collection device for stool samplingECCO'25Year: 2025
Authors: Pasi, G.(1);Antari, A.(2);Masson, D.(2);Dejoie, T.(2);Caillon, H.(2);Collins, M.(1);Bourreille, A.(1);Le Berre, C.(1)*;
(1)Nantes University Teaching Hospital, Gastroenterology, Nantes, France;(2)Nantes University Teaching Hospital, Biology, Nantes, France; Institut des Maladies de l’Appareil Digestif (IMAD) Hépato-Gastro-Entérologie et Assistance Nutritionnelle Inserm CIC 1413 Nantes Université CHU Nantes F-44000 Nantes France.
P0487: Understanding the learning curve of intestinal ultrasound in IBD: a comparative study between novice, regular and expertECCO'25Year: 2025
Authors: Bove, L.(1)*;Meyer, J.(2);Collins, M.(1);Frampas, E.(2);Bourreille, A.(1,3);Le Berre, C.(1,3);
(1)CHU Nantes, Institut des Maladies de l’Appareil Digestif IMAD- Hépato-Gastro-Entérologie et Assistance Nutritionnelle- Inserm CIC 1413- Nantes Université, Nantes, France;(2)CHU Nantes, Central Department of Radiology and Medical Imaging- Nantes Université, Nantes, France;(3)CHU Nantes, Institut des Maladies de l’Appareil Digestif IMAD- Inserm UMR 1235- Nantes Université, Nantes, France;
P0488: The course of Crohn's Disease in the Biologics Era: an in depth Single-Center Tertiary Cohort Study in Belgium.ECCO'25Year: 2025
Authors: Vuckovic, C.(1)*;Cremer, A.(1);Minsart, C.(1);Bottieau, J.(2);Franchimont, D.(1);Liefferinckx, C.(1);
(1)HUB-Erasme, Gastroenterology, Brussels, Belgium;(2)Université Libre de Bruxelles ULB, Laboratoire de Gastro-Entérologie Expérimentale LGE, Brussels, Belgium;
P0489: The impact of inflammatory bowel disease and disease activity on patients’ sexualityECCO'25Year: 2025
Authors: Szymanska, E.(1)*;Kisielewska , L.(2);Kotkowicz-Szczur, M.(3);Kisielewski, R.(4);Kierkus, J.(5);
(1)Children's Memorial Health Institute, Department of Gastroenterology- Hepatology- Feeding Disorders and Pediatrics, Warsaw, Poland;(2)The Centre of Oncology- Bialystok, Department of Gynecologic Oncology, Białystok, Poland;(3)Children's Memorial Health Institute, Department of Gastroenterology- Hepatology- Feeding Disorders and Paediatrics, Warsaw, Poland;(4)The Centre of Oncology- Bialystok, Department of Gynecologic Oncology, Bialystok, Poland;(5)The Children's Memorial Health Institute- Warsaw- Poland, Department of Gastroenterology- Hepatology- Feeding Disorders and Paediatrics, Warsaw, Poland;
P0490: Diagnosis and treatement of latent tuberculosis infection in patients with chronic Inflammatory Bowel Disease candidates for anti-TNFα therapy in a tuberculosis endemic countryECCO'25Year: 2025
Authors: Mouslim, I.(1)*;jioua, C.(1);touibi, A.(2);ouahid, S.(3);nejjari, F.(3);berrag , S.(3);Tarik , A.(4);Mouna, T.(4);
(1)Mohamed V Military training hospital- Rabat- Morocco, Department of Gastroenterology I, Rabat, Morocco;(2)Mohamed V military training hospital, gastroenterology departement, rabat, Morocco;(3)mohamed V military training hospital, gastroenterology department, rabat, Morocco;(4)Mohamed V military training hospital, Gastro enterology department, rabat, Morocco;
P0491: Cumulative Inflammatory Burden and Structural Bowel Changes as Independent Risk Factors for Colonic Dysplasia in Ulcerative Colitis: A Case-Control StudyECCO'25Year: 2025
Authors: Park, D.(1)*;Oh, J.E.(1);Choi, S.(1);Park, J.(1);Park, S.J.(1);Cheon, J.H.(1);Kim, T.I.(1);ParkAssistant professor, J.J.(2);
(1)Yonsei University College of Medicine, Internal Medicine, Seoul, Korea- Republic Of;(2)Yonsei University College of Medicine, Department of Internal Medicine- Severance Hospital, Seoul, Korea- Republic Of;
P0492: Development and Assessment of a Novel Ulcerative Colitis–Specific Quality of Life Questionnaire: A Prospective, Multi-Institutional StudyECCO'25Year: 2025
Authors: Park, J.(1)*;Tae Il , K.(1);Jae Hee, C.(1);
(1)Yonsei university college of medicine, Internal medicine, Seoul, Korea- Republic Of;
1. Maaser C, Sturm A, Vavricka SR, Kucharzik T, Fiorino G, Annese V,et al. ECCO-ESGAR guideline for diagnostic assessment in IBD part1: initial diagnosis, monitoring of known IBD, detection of complications.J Crohns Colitis 2019;13:144-64.2. Chang JT. Pathophysiology of inflammatory bowel diseases. N EnglJ Med 2020;383:2652-64.3. Lamb CA, Kennedy NA, Raine T, Hendy PA, Smith PJ, Limdi JK, etal. British Society of Gastroenterology consensus guidelines onthe management of inflammatory bowel disease in adults. Gut2019;68(Suppl 3):S1-106.4. Turner D, Ricciuto A, Lewis A, D’Amico F, Dhaliwal J, Griffiths AM,et al. STRIDE-II: an update on the selecting therapeutic targets ininflammatory bowel disease (STRIDE) initiative of the internationalorganization for the study of IBD (IOIBD): determiningtherapeutic goals for treat-to-target strategies in IBD. Gastroenterology2021;160:1570-83.5. Knowles SR, Graff LA, Wilding H, Hewitt C, Keefer L, Mikocka-WalusA. Quality of life in inflammatory bowel disease: a systematic reviewand meta-analyses-part I. Inflamm Bowel Dis 2018;24:742-51.6. Keller R, Mazurak N, Fantasia L, Fusco S, Malek NP, Wehkamp J, etal. Quality of life in inflammatory bowel diseases: it is not all aboutthe bowel. Intest Res 2021;19:45-52.7. Knowles SR, Keefer L, Wilding H, Hewitt C, Graff LA, Mikocka-WalusA. Quality of life in inflammatory bowel disease: a systematic reviewand meta-analyses-part II. Inflamm Bowel Dis 2018;24:966-76.8. Yarlas A, Maher S, Bayliss M, Lovley A, Cappelleri JC, BushmakinAG, et al. The inflammatory bowel disease questionnaire in randomizedcontrolled trials of treatment for ulcerative colitis: systematicreview and meta-analysis. J Patient Cent Res Rev 2020;7:189-205.9. Guyatt G, Mitchell A, Irvine EJ, Singer J, Williams N, Goodacre R, etal. A new measure of health status for clinical trials in inflammatorybowel disease. Gastroenterology 1989;96:804-10.10. Stjernman H, Grännö C, Bodemar G, Järnerot G, Ockander L, TyskC, et al. Evaluation of the inflammatory bowel disease questionnairein Swedish patients with Crohn's disease. Scand J Gastroenterol
P0493: Patient satisfaction with IBD undergoing colonoscopy: a multicenter cross-sectional studyECCO'25Year: 2025
Authors: Napolitano, D.(1)*;Lo Cascio, A.(2);Bozzetti, M.(3);Povoli, A.(4);Grubissa, S.(4);Molino, L.(5);Marino, M.(4);Berretti, D.(4);Grilli, F.(1);Calvez, V.(1);Puca , P.(1);Fiorino, G.(6);Gasbarrini, A.(7);Scaldaferri, F.(7);
(1)Fondazione Policlinico Gemelli IRCCS, Cemad, Rome, Italy;(2)La Maddalena Cancer Center, Main Regional Center for Supportive and Palliative Care, Palermo, Italy;(3)Nursing and Allied Health Professions Directorate, Istituto Ortopedico Rizzoli, Bologna, Italy;(4)Department of Gastroenterology, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy;(5)Università Cattolica Sacro Cuore, Università Cattolica Sacro Cuore, Rome, Italy;(6)San Camillo-Forlanini Hospital, IBD Unit- Department of Gastroenterology and Digestive Endoscopy, Rome, Italy;(7)Fondazione Policlinico Gemelli IRCCS and Università Cattolica Sacro Cuore, Cemad, Rome, Italy;
1. Bessissow, T., Van Keerberghen, C.-A., Van Oudenhove, L., Ferrante, M., Vermeire, S., Rutgeerts, P., & Van Assche, G. (2013). Anxiety is associated with impaired tolerance of colonoscopy preparation in inflammatory bowel disease and controls. Journal of Crohn’s & Colitis, 7(11), e580-587. https://doi.org/10.1016/j.crohns.2013.04.011
2. Minciullo A, Tartaglini D, Colombo B, Filomeno L, Di Muzio M. Assessing validity and reliability of a new tool: the ECSQ (Endoscopy Customer Satisfaction Questionnaire) in Italian for customer satisfaction in digestive endoscopy. Ann Ig. 2022 Mar-Apr;34(2):166-176. doi: 10.7416/ai.2022.2476. PMID: 35088823.
3. Pena, L. R., Mardini, H. E., & Nickl, N. J. (2005). Development of an instrument to assess and predict satisfaction and poor tolerance among patients undergoing endoscopic procedures. Digestive Diseases and Sciences, 50(11), 1860-1871. https://doi.org/10.1007/s10620-005-4442-0
P0494: Serum regenerating islet-derived 3-alpha (REG3α) is a new prognostic biomarker in Crohn’s DiseaseECCO'25Year: 2025
Authors: Claytor, J.(1)*;Bourgonje, A.R.(1);Ibing, S.(2,3);Cohen, L.(1);Colombel, J.F.(1);Ferrara, J.(4);Levine, J.E.(4);Ungaro, R.C.(1);
(1)Mount Sinai Hospital, Henry D. Janowitz Division of Gastroenterology, New York City, United States;(2)Hasso Plattner Institute- Digital Engineering Faculty, University of Potsdam, Potsdam, Germany;(3)Hasso Plattner Institute for Digital Health, Mount Sinai Hospital, New York City, United States;(4)Mount Sinai Hospital- Tisch Cancer Institute, Hematology/Medical Oncology, New York City, United States;
(1) Ferrara JLM, Harris AC, Greenson JK, et al. Regenerating islet-derived 3-alpha is a biomarker of gastrointestinal graft-versus-host disease. Blood. 2011;118(25):6702-6708. doi: 10.1182/blood-2011-08-375006
(2) Major-Monfried H, Renteria AS, Pawarode A, et al. MAGIC biomarkers predict long-term outcomes for steroid-resistant acute GVHD. Blood. 2018;131(25):2846-2855. doi:10.1182/blood-2018-01-822957
(3) Marafini I, Di Sabatino A, Zorzi F, et al. Serum regenerating islet-derived 3-alpha is a biomarker of mucosal enteropathies. Aliment Pharmacol Ther. 2014;40(8):974-981. doi:10.111/apt.12920
(4) Zhao D, Kim YK, Jeong S, et al. Survival Signal REG3a prevents crypt apoptotsis to control acute gastrointestinal graft-versus-host disease. J Clin Invest. 2018;128(11):4970-4979. doi:10.1172/JCI99261
P0495: Impact of the HLA DQA1*05 allele on the efficacy of vedolizumab treatment in inflammatory bowel disease.ECCO'25Year: 2025
Authors: Castro Torres, S.(1)*;Ramiro cuenca, L.(1);Rodríguez-Moranta, F.(1);Rodríguez-Alonso, L.(1);Ruiz-Cerulla, A.(1);Sánchez-Pastor, E.(1);Antón-Güell, S.(1);Guardiola Capon, J.(1);
(1)Hospital Universitario Bellvitge, IBD unit, Hospitalet de Llobregat, Spain;
P0496: Upadacitinib for Patients with Crohn’s Disease and Previous Biologic Failure: A Systematic Review and Meta-AnalysisECCO'25Year: 2025
Authors: Campedelli, L.(1)*;Perim, V.(2);Hueb, R.(3);
(1)Boston University/Boston Medical Center, Internal Medicine, Boston- MA, United States;(2)University of Alabama at Birmingham, General Surgery, Birmingham- AL, United States;(3)Universidade Santo Amaro, Medicine, Sao Paulo- SP, Brazil;
1.Loftus EV, Panés J, Lacerda AP, et al. Upadacitinib Induction and Maintenance Therapy for Crohn’s Disease. The New England Journal of Medicine. 2023;388(21):1966-1980. doi:https://doi.org/10.1056/nejmoa2212728
2.Sandborn WJ, Feagan BG, Loftus EV, et al. Efficacy and Safety of Upadacitinib in a Randomized Trial of Patients With Crohn’s Disease. Gastroenterology. 2020;158(8):2123-2138.e8. doi:https://doi.org/10.1053/j.gastro.2020.01.047
P0497: Faecal Incontinence and Urgency in IBD Patients on Biologic Therapy in Remission: Prevalence and Risk FactorsECCO'25Year: 2025
Authors: Jelakovic, M.(1)*;Peretin, L.(2);Kodvanj, I.(1);Brinar, M.(1);Turk, N.(1);Grgic, D.(1);Kunovic, A.(1);Cukovic-Cavka, S.(1);Krznaric, Z.(1);
(1)UHC Zagreb, Department of Gastroenterology and Hepatology, Zagreb, Croatia;(2)OB Varazdin, Department of Gastroenterology and Hepatology, Varazdin, Croatia;
