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P114: Potassium competitive acid blocker, revaprazan, prevented indomethacin-induced intestinal permeability through tightening TJsECCO '18 Vienna
Year: 2018
Authors:

K.B. Hahm1*, J.M. Park2, Y.M. Han2

1CHA University, Gastroenterology, Seongnam, South Korea, 2CHA Cancer preventive Research center, Seongnam, South Korea

P115: Appendectomy and ulcerative colitis: role of innate immunity in the inflammatory response of the appendicular and colonic mucosaECCO '18 Vienna
Year: 2018
Authors:

L. Saadeh1*, I. Angriman1, M. Scarpa2, C. Mescoli3, G. Procida1, A. Kotsafti2, F. Cavallin2, M. Rugge4, R. Bardini1, I. Castagliuolo5, M. Scarpa2

1University of Padova, Department of Surgery, Oncology and Gastroenterology, Padova, Italy, 2IRCCS IOV Istituto Oncologico Veneto, Padova, Italy, 3Azienda Ospedaliera - Università di Padova, Padova, Italy, 4University of Padova, Department of Medicine, Padova, Italy, 5University of Padova, Department of Molecular Medicine, Padova, Italy

P116: A computable, causal biological network model suite for mechanistic evaluation of ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

J. Szostak, M. Talikka, M. Florian, R. Gadaleta*, M. Peitsch, J. Hoeng

Philip Morris International Research and Development, System Toxicology, Neuchatel, Switzerland

P117: Serum proteomic analysis characterises newly diagnosed Crohn’s disease and ulcerative colitis depending on the age at diagnosisECCO '18 Vienna
Year: 2018
Authors:

S. Verstockt1*, E. Glorieus2, M. De Decker3, B. Verstockt4,5, N. Ardeshir Davani5, V. Ballet4, G. Van Assche4,5, P. Hindryckx2, M. Ferrante4,5, D. Laukens2, F. Mana3, M. De Vos2, S. Vermeire4,5, I. Cleynen1

1University of Leuven, Department of Human Genetics, Laboratory for Complex Genetics, Leuven, Belgium, 2University Hospital Ghent, Department of Gastroenterology, Ghent, Belgium, 3University Hospital Brussels, Department of Gastroenterology, Brussels, Belgium, 4University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, 5University of Leuven, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), Leuven, Belgium

P118: Identification of colitis-associated bacteria in intestine of inflammatory bowel disease patientsECCO '18 Vienna
Year: 2018
Authors:

J. Seishima*, N. Iida, E. Mizukoshi, S. Kaneko

Graduate School of Medicine, Kanazawa University, Gastroenterology, Kanazawa, Ishikawa, Japan

P119: The immunohistochemical assessment of CD30+ lymphocytes in the intestinal mucosa facilitates diagnosis of paediatric ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

O. Fabian1*, O. Hradsky2, T. Drskova3, F. Mikus1, J. Zamecnik1, J. Bronsky3

1Motol University Hospital, Department of Pathology and Molecular Medicine, Prague, Czech Republic, 2Motol University Hospital, – Department of Paediatrics, Prague, Czech Republic, 3Motol University Hospital, Department of Paediatrics, Prague, Czech Republic

P120: Vitamin D deficiency in Crohn’s diseaseECCO '18 Vienna
Year: 2018
Authors:

C. Haifer1*, R.M. Lucas2, M.W. Clarke3, I. Lawrance4,5, P.H. Hart6, J.R. Center7,8, J.A. Eisman7,8, S. Ghaly1

1St Vincent's Hopspital, Sydney, Gastroenterology, Sydney, Australia, 2The Australian National University, National Centre for Epidemiology and Population Health, Canberra, Australia, 3The University of Western Australia, Centre for Microscopy, Characterisation and Analysis, Perth, Australia, 4University of Western Australia, School of Medicine and Pharmacology, Faculty of Health and Medical Sciences, Perth, Australia, 5St John of God Hospital, Centre for Inflammatory Bowel Diseases, Subiaco, Australia, 6Telethon Kids Institute, Inflammation, Subiaco, Australia, 7The Garvan Institute of Medical Research, Osteoporosis and Bone Biology, Sydney, Australia, 8St Vincent's Hospital Sydney, Endocrinology, Sydney, Australia

P121: Characterising and managing issues with food-related quality of life in inflammatory bowel disease: a qualitative study of patients and healthcare professionalsECCO '18 Vienna
Year: 2018
Authors:

W. Czuber-Dochan1*, M. Morgan2, M. Lomer1, J.O. Lindsay3, G. Robert4, K. Whelan1

1King's College London, Faculty of Life Sciences and Medicine, Department of Nutritional Sciences, London, UK, 2King's College London, Institute of Pharmacological Sciences, London, UK, 3Bart’s and the London NHS Trust, Gastroenterology Department, London, UK, 4King's College London, Faculty of Nursing, Midwifery and Palliative Care, London, UK

P122: Vitamin D activates human intestinal fibroblastsECCO '18 Vienna
Year: 2018
Authors:

L. Gisbert-Ferrándiz1*, P. Salvador1, D.C. Macias-Ceja2, J. Cosín-Roger2, D. Ortiz-Masiá3,4, F. Navarro-Vicente5, S. Calatayud1,4, C. Hernández2, M.D. Barrachina1,4

1University of Valencia, Pharmacology, Valencia, Spain, 2Fisabio Hospital Dr Peset, Valencia, Spain, 3University of Valencia, Medicine, Valencia, Spain, 4CIBERehd, Valencia, Spain, 5Hospital of Manises, Servicio de Cirugía, Valencia, Spain

P123: The effect of necrosis inhibition on acute DSS colitis model of inflammatory bowel diseaseECCO '18 Vienna
Year: 2018
Authors:

D. Lee1,2*, J.S. Koo2, C.H. Kim1, S.H. Hwang1, J.W. Choe2, S.Y. Kim2, S.W. Jung2, H.J. Yim2, Y.T. Jeen2, S.W. Lee2

1Korea University Ansan Hospital, Internal Medicine, Seoul, South Korea, 2Korea University College of Medicine, Seoul, South Korea

P124: An investigation of taste preference to oral nutritional supplement drinks (ONS) in adolescent and adult Crohn’s disease (CD) and attitudes towards their long-term useECCO '18 Vienna
Year: 2018
Authors:

K. Keetarut1*, N. Richards2, N. Davies3

1University College London Hospital, Nutrition and Dietetics, London, UK, 2University College London, London, UK, 3University College London, London, UK

P125: Basement membrane remodelling as a biomarker for monitoring disease activity in Crohn’s disease patients: the role of lamininECCO '18 Vienna
Year: 2018
Authors:

M.L. Olesen1,2*, A. Di Sabatino3,4, G. Mazza4, T. Manon-Jensen1, P. Giuffrida3, M. Pinzani4, A. Krag2, M. Karsdal1, J. Kjeldsen2, J.H. Mortensen1

1Nordic Bioscience A/S, Biomarkers and Research, Herlev, Denmark, 2University of Southern Denmark and Odense University Hospital, Department of Medical Gastroenterology, Odense, Denmark, 3San Matteo Hospital Foundation and University of Pavia, Department of Internal Medicine, Pavia, Italy, 4University College of London, Institute for Liver and Digestive Health, London, UK

P126: Post-inflammatory polyps do not predict colorectal neoplasia in patients with inflammatory bowel disease: a multinational retrospective cohort studyECCO '18 Vienna
Year: 2018
Authors:

R. Mahmoud1,2*, S. Shah2, J. ten Hove1, J. Torres2,3, E. Mooiweer1, D. Castaneda2, J. Glass2, J. Elman4, A. Kumar2, J. Axelrad4, T. Ullman2, J.-F. Colombel2, B. Oldenburg1, S. Itzkowitz2

1University Medical Center Utrecht, Gastroenterology and Hepatology, Utrecht, The Netherlands, 2Icahn School of Medicine at Mount Sinai, Division of Gastroenterology, Department of Medicine, New York City, USA, 3Hospital Beatriz Ângelo, Division of Gastroenterology, Surgical Department, Loures, Portugal, 4Icahn School of Medicine at Mount Sinai, Department of Medicine, New York City, USA

P127: Developing a colorectal cancer risk prediction tool for patients with ulcerative colitis and low-grade dysplasiaECCO '18 Vienna
Year: 2018
Authors:

M. Kabir1*, K. Curtius2, I. Al-Bakir1,2, C.-H.R. Choi1,2, T. Graham2, A. Wilson1, A. Hart1

1St Mark's Hospital, London North West Hospitals NHS Trust, London, UK, 2Queen Mary University of London, Barts Cancer Institute, London, UK

P128: Development of the Paediatric Inflammatory Crohn's MRE Index (PICMI)- results from the ImageKids StudyECCO '18 Vienna
Year: 2018
Authors:

D. Turner1, M. Gavish2, G. Focht1*, T.D. Walters3, P.C. Church3, M.-L. Greer4, D.A. Castro5, R. Cytter-Kuint6, J.S. Hyams7, F.M. Ruemmele8, R.K. Russell9, J. Martín de-Carpi10, L.-T. Pratt11, A.M. Griffiths3, The ImageKids Study

1Shaare Zedek Medical Center, The Juliet Keidan Institute of Paediatric Gastroenterology and Nutrition, Jerusalem, Israel, 2Hebrew University of Jerusalem, Computer Science, Jerusalem, Israel, 3Hospital for Sick Children, Division of Gastroenterology, Toronto, Canada, 4The Hospital for Sick Children, Department of Diagnostic Imaging, Toronto, Canada, 5Hospital for Sick Children, Department of Diagnostic Imaging, Toronto, Canada, 6Shaare Zedek Medical Center, Pediatric Radiology Unit, Jerusalem, Israel, 7Connecticut Children's Medical Center, Division of Digestive Diseases, Hepatology, and Nutrition, Hartford, USA, 8Hôpital Necker Enfants Malades, Department of Pediatric Gastroenterology, Paris, France, 9Royal Hospital for Children,, Department of Paediatric Gastroenterology, Glasgow, UK, 10Hospital Sant Joan de Deu, Department of Gastroenterology, Hepatology and Pediatric Nutrition, Barcelona, Spain, 11Tel Aviv Sourasky Medical Center, Diagnostic Imaging Division, Tel Aviv, Israel

P129: A randomised crossover trial of conventional vs. virtual chromoendoscopy for colitis surveillance: dysplasia detection, feasibility, and patient acceptability (CONVINCE)ECCO '18 Vienna
Year: 2018
Authors:

S. Gulati*, P. Dubois, B. Carter, A. Emmanuel, A. Haji, B. Hayee

King's College Hospital NHS Foundation Trust, London, UK

P130: A clear look into the bowel without cleaning it: simultaneous PET/MRI enterography (18F-FDG) for monitoring inflammatory activity in patients with ulcerative coliti—a prospective randomised controlled trialECCO '18 Vienna
Year: 2018
Authors:

J. Langhorst1*, Y. Li2, A. Koch1, A. Dechene3, G. Dobos4, K. Beiderwellen5, T. Lauenstein6, L. Umutlu2

1University of Duisburg-Essen, Integrative Gastroenterology, Kliniken Essen-Mitte, Essen, Germany, 2University Hospital Essen, Institute of Diagnostic and Interventional Radiology and Neuroradiology, Essen, Germany, 3University Hospital Essen, Clinic for Gastroenterology and Hepatology, Essen, Germany, 4University of Duisburg-Essen, Integrative and Internal Medicine, Essen, Germany, 5University of Duisburg-Essen, Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany, 6University Duisburg-Essen, Department of Diagnostic and Interventional Radiology and Neuroradiology, Essen, Germany

P131: Fatigue most frequently reported reason for work productivity loss in inflammatory bowel disease patientsECCO '18 Vienna
Year: 2018
Authors:

S. van Gennep1*, A.G. de Boer2, K.G. Gecse1, C.I. Ponsioen1, J.K. Sluiter2, G.R. D'Haens1, M. Löwenberg1

1Academic Medical Center, Gastroenterology and Hepatology, Amsterdam, The Netherlands, 2Academic Medical Center, Coronel Institute of Occupational Health, Amsterdam, The Netherlands

P132: Analysis of various central endoscopy reading methodologies in the BERGAMOT exploratory induction cohort evaluating etrolizumab in Crohn’s DiseaseECCO '18 Vienna
Year: 2018
Authors:

W. Reinisch1*, D.S. Mishkin2, Y.S. Oh3, S. Schreiber4, R. Maciuca3, R. Jacob5, A. Hassanali3, U. Arulmani3, M. Daperno6

1Medical University of Vienna, Vienna, Austria, 2Atrius Health, Boston, USA, 3Genentech, Inc., South San Francisco, USA, 4Christian-Albrechts-University, Kiel, Germany, 5Roche Products Limited, Welwyn Garden City, UK, 6AO Ordine Mauriziano di Torino, Turin, Italy

P133: Cognitive debriefing interviews (phase 2B) towards developing a Patient Reported Outcome measure for Paediatric ulcerative colitis- the TUMMY-UCECCO '18 Vienna
Year: 2018
Authors:

L. Marcovitz1, A. Nissan1, A. Horesh1, D. Mack2, S. Hussey3, A. Otley4, N. Croft5, M. Kappelman6, B. Mclean6, A. Bousvaros7, M.Q. Lewis6, A. Griffiths8, D. Turner1*

1Shaare Zedek Medical Center, Institute of Pediatric Gastroenterology, Jerusalem, Israel, 2CHEO, Ottawa, Canada, 3National Children’s Research Centre and University College Dublin, Dublin, Ireland, 4IWK, Halifax, Canada, 5Barts and the London School of medicine, Queen Mary University of London, London, UK, 6UNC Health Care, North Carolina, USA, 7Boston Children Hospital, Boston, USA, 8SickKids, Toronto, Canada