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P054: Innate lymphoid cells in paediatric inflammatory bowel diseaseECCO '18 Vienna
Year: 2018
Authors:

A. Van Acker1*, E. Kvedaraite1,2, M. Lourda1,2, M. Ideström3, J.-I. Henter2, M. Svensson1, J. Mjösberg1

1Karolinska Institute, Center for Infectious Medicine, Stockholm, Sweden, 2Karolinska Institute, Karolinska University Hospital, Childhood Cancer Research Unit, Department of Women’s and Children’s Health, Stockholm, Sweden, 3Karolinska Institute, Karolinska University Hospital, Paediatric Gastroenterology, Hepatology and Nutrition Unit, Department of Women’s and Children’s Health, Stockholm, Sweden

P055: Immunological cross-reactivity of anti-drug antibodies to adalimumab and ABP 501ECCO '18 Vienna
Year: 2018
Authors:

J. Miller*, M. Starcevic Manning, I. Wala, H. Wang, E. Krishnan, A. Kaliyaperumal, N. Zhang, D. Mytych

Amgen Inc., Biosimilars, Thousand Oaks, USA

P056: South Asian ethnicity drives differences in microbial and metabolic profiling in a newly diagnosed ulcerative colitis cohortECCO '18 Vienna
Year: 2018
Authors:

R. Misra1*, M. Sarafian2, A. Pechilvanis2, N. Ding3, C. Boulange2, J. Marchesi2, E. Holmes2, O. Faiz4, N. Arebi5

1St. Marks Hospital, Gastroenterology, London, UK, 2Imperial College London, London, UK, 3St Vincent's Hospital Melbourne, Fitzroy, Australia, 4St Mark's Academic Institute, Surgical Epidemiology, Trials and Outcomes Unit (SETOC), London, UK, 5St Mark's Academic Institute, Gastroenterology, London, UK

P057: Proteomic analysis highlights divergences and convergences between ileal and colonic pathological processes involved in Crohn’s ulcersECCO '18 Vienna
Year: 2018
Authors:

N. Pierre1*, C. Reenaers2, C. Van Kemseke2, J.-P. Loly2, G. Mazzucchelli3, N. Smargiasso3, D. Baiwir3, D. Morsa3, E. De Pauw3, M.-A. Meuwis1,2, E. Louis1,2

1Uliege, GIGA-R Translational Gastroenterology, Liège, Belgium, 2CHU de Liège, Hepato-Gastroenterology and Digestive Oncology, Liège, Belgium, 3Uliege, Laboratory of Mass Spectrometry, Chemistry, Liège, Belgium

P058: Phosphodiesterase 8A domains at the site of leucocyte–endothelial cell adhesion in ulcerative colitis submucosaECCO '18 Vienna
Year: 2018
Authors:

N. Ovadóttir1,2,3*, K. Danielsen3, K. Nielsen4, P. Epstein5, S. Brocke6, M. Kaminski2, A. Vang2,3,6

1Roskilde University, Department of Science and Environment, Roskilde, Denmark, 2National Hospital of the Faroe Islands, Department of Diagnostic Medicine, Torshavn, Faroe Islands, 3University of the Faroe Islands, Department of Health Sciences, Tórshavn, Faroe Islands, 4National Hospital of the Faroe Islands, Department of Medicine, Torshavn, Faroe Islands, 5University of Connecticut Health Center, Department of Cell Biology, Farmington, USA, 6University of Connecticut Health Center, Department of Immunology, Farmington, USA

P059: Test of stability in stool extracts for F-calprotectinECCO '18 Vienna
Year: 2018
Authors:

E. Aardal Eriksson*, J. Andersson

Linköping University Hospital, Clinical Chemistry, Linköping, Sweden

P060: Post-inflammatory visceral pain induced by DNBS: Preclinical features for novel therapeuticsECCO '18 Vienna
Year: 2018
Authors:

E. Lucarini1*, L. Di Cesare Mannelli1, L. Micheli1, E. Trallori1, L. Antonioli2, M. Fornai2, C. Blandizzi2, C. Ghelardini1

1University of Florence, Department of Neuroscience, Psychology, Drug Research and Child Health, Neurofarba, Pharmacology and Toxicology Section, Florence, Italy, 2University of Pisa, Department of Clinical and Experimental Medicine, Unit of Pharmacology and Pharmacovigilance, Pisa, Italy

P061: Probiotic kimchi prevented colitis-associated cancerECCO '18 Vienna
Year: 2018
Authors:

K.B. Hahm1*, Y.M. Han2, J.M. Park2

1CHA University, Department of Gastroenterology, Seongnam, South Korea, 2CHA Cancer Preventive Research Center, Seongnam, South Korea

P062: Small intestinal lactulose and sucralose hyper-permeability in inflammatory bowel diseaseECCO '18 Vienna
Year: 2018
Authors:

A.K. Al-Saffar1,2, A.H. Md.1, G. Hall1, P. Hellström1, D.-L. Webb1*

1Uppsala University, Department of Medical Sciences, Uppsala, Sweden, 2Baghdad University, College of Veterinary Medicine. Department of Surgery and Obstetrics, Baghdad, Iraq

P063: Faecal calprotectin as a non-invasive treatment target to predict mucosal healing and histological remission in asymptomatic ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

A. Correia Varela Almeida1*, J.M. Vázquez Morón1, E. Gómez Delgado1, H. Pallarés Manrique1, A. Talavera Fabuel2, A. Bejarano García1

1Juan Ramón Jiménez Hospital, Gastroenterology, Huelva, Spain, 2Infanta Elena Hospital, Gastroenterology, Huelva, Spain

P064: Intestinal expression of LAG-3 correlates with inflammatory activity and response to biological therapy in ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

S. Slevin1*, M. Tan1, C. Lahiff1, K. Williamson1, A. Geremia1, S. Hughes2, K. Leavens2, K. Nevin2, D.J.B. Marks2, R. Tarzi2, N. Srinivasan2, C. Arancibia1, S. Keshav1

1University of Oxford, Translational Gastroenterology Unit, Oxford, UK, 2Experimental Medicine Unit, GSK, Gunnels Wood Rd, Stevenage, Hertfordshire, SG1 2NY, UK

P065: REDD1/autophagy-driven NETosis promotes IL-1β-mediated inflammation in active ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

A. Chrysanthopoulou1, I. Angelidou1, A. Mitsios1, S. Arelaki2, A. Arampatzioglou1, K. Kambas1, D. Ritis1, V. Tsironidou1, I. Moschos3,4, I. Mitroulis5, G. Kouklakis3,4, P. Skendros1,3*

1Democritus University of Thrace, Laboratory of Molecular Hematology, University Hospital of Alexandroupolis, Alexandroupolis, Greece, 2Democritus University of Thrace, Department of Pathology, University Hospital of Alexandroupolis, Alexandroupolis, Greece, 3Democritus University of Thrace, First Department of Internal Medicine, University Hospital of Alexandroupolis, Alexandroupolis, Greece, 4Democritus University of Thrace, Gastrointestinal Endoscopy Unit, University Hospital of Alexandroupolis, Alexandroupolis, Greece, 5Technische Universität Dresden, Department of Clinical Pathobiochemistry, Institute for Clinical Chemistry and Laboratory Medicine, Faculty of Medicine, Dresden, Germany

P066: Pharmacologic inhibition of integrin αvβ6 causes tumour shrinkage in colitis associated mouse colon tumoursECCO '18 Vienna
Year: 2018
Authors:

P. Busenhart*, L. Hering, K. Atrott, E. Patsenker, F. Stickel, K. Bäbler, B. Weder, A. Wyss, G. Rogler, M. Spalinger, M. Scharl

University Hospital Zürich, Department for gastroenterology and hepatology, Zürich, Switzerland

P067: Proliferating intestinal macrophage populations in human inflammatory bowel diseaseECCO '18 Vienna
Year: 2018
Authors:

E. McDonald1*, P. Wright1, C. Bain2, A. Bravo-Blas1, E. Robertson3,4, A. Mowat1, S. Milling1, D. Gaya4

1University of Glasgow, Infection, Immunity and Inflammation, Glasgow, UK, 2University of Edinburgh, MRC Centre for Inflammation Research, Edinburgh, UK, 3Glasgow Royal Infirmary, Gastroenterology Unit, Glasgow, UK, 4Glasgow Royal Infirmary, Glasgow, UK

P068: Loss of PTPN22 abrogates the beneficial effect of faecal microbiota transferECCO '18 Vienna
Year: 2018
Authors:

M. Spalinger*, M. Schwarzfischer, C. Gottier, L. Hering, S. Lang, G. Rogler, M. Scharl

University Hospital Zürich, Gastroenterology and Hepatology, Zürich, Switzerland

P069: Intraperitoneal injection of bone marrow derived-mesenchymal stem cells increases total number of colon-infiltrating inflammatory dendritic cells and macrophages and aggravates colitis in BALBc miceECCO '18 Vienna
Year: 2018
Authors:

A. Acovic1*, B. Simovic Markovic2, M. Gazdic2, A. Arsenijevic2, A. Volarevic3, T. Kanjevac1, N. Jovicic2, J. Jakovljevic2, M. Arsenijevic2, N. Arsenijevic2, M.L. Lukic2, V. Volarevic2

1Faculty of Medical Sciences, University of Kragujevac Serbia, Department of Dentistry, Kragujevac, Serbia, 2Centre for Molecular Medicine and Stem Cell research, Faculty of Medical Sciences University of Kragujevac Serbia, Department of Microbiology and Immunology, Kragujevac, Serbia, 3Faculty of Medical Sciences, University of Kragujevac Serbia, Department of Psychology, Kragujevac, Serbia

P070: Mucosal immune signature in IBD: To what extent α4β7-expressing peripheral T cells reflect T-lymphocyte population resident in gut mucosa?ECCO '18 Vienna
Year: 2018
Authors:

S. Reich-Zeliger1, N. Friedman1, L. Lichtenstein2,3*

1Weizmann Institute of Science, Department of Immunology, Rehovot, Israel, 2Rabin Medical Center, Gastroenterology, Petach Tikva, Israel, 3Tel Aviv University, Sackler Faculty of Medicine, Tel Aviv, Israel

P071: Cancer preventive effect of recombinant TRAIL by ablation of oncogenic inflammation in colitis-associated cancer rather than anticancer effectECCO '18 Vienna
Year: 2018
Authors:

K.B. Hahm1*, J.M. Park2, Y.M. Han2, S. Hong3, K.C. Lee4

1CHA University, Gastroenterology, Seongnam, South Korea, 2CHA Cancer Preventive Research Center, Seongnam, South Korea, 3Gachon University, Incheon, South Korea, 4Sungkyunkwan University, Suwon, South Korea

P072: Safety analysis of vedolizumab during pregnancy: Findings from a reproductive study in monkeysECCO '18 Vienna
Year: 2018
Authors:

D. Crawford*, M. Friedman

Takeda Development Center Americas, Deerfield, IL, USA

P073: Changes in gut microbial signatures differentiate behavioural Crohn’s disease phenotypes; an in silico approachECCO '18 Vienna
Year: 2018
Authors:

N. Dovrolis1, G. Kolios1*, I. Drygiannakis2, E. Filidou1, L. Kandilogiannakis1, K. Arvanitidis1, I. Tentes3, V. Valatas2

1Democritus University of Thrace, Laboratory of Pharmacology, Faculty of Medicine, Alexandroupolis, Greece, 2University of Crete, Laboratory of Gastroenterology, Faculty of Medicine, Heraklion, Greece, 3Democritus University of Thrace, Laboratory of Biochemistry, Faculty of Medicine, Alexandroupolis, Greece