¹Agaplesion Markus Hospital, Frankfurt/Main, Germany, ²Adelphi Real World, Bollington, UK, ³Pfizer Inc., Groton, CT, USA, ⁴Pfizer Inc., Collegeville, PA, USA, ⁵Pfizer Germany GmbH, Berlin, Germany, ⁶Pfizer Inc., New York, NY, USA

¹Ospedale San Filippo Neri, IBD Unit, Roma, Italy, ²UOC Gastroenterologia ed Endoscopia Digestiva Diagnostica e Operativa A.O. San Camillo-Forlanini, Roma, Italy, ³IBD Unit, Presidio Columbus Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica, Rome, Italy, ⁴Statistician - Italian Group for the study of Inflammatory Bowel Disease, Firenze, Italy, ⁵U.O. Gastroenterologia, Ospedale di Rho, ASST Rhodense, Rho (Milano), Italy, ⁶Sezione di Gastroenterologia, Azienda Policlinico Universitaria Bari, Bari, Italy, ⁷Department of Surgical Sciences, University of Turin, Torino, Italy, ⁸IBD Centre, Humanitas Clinical and Research Centre; *Department of Biomedical Sciences, Humanitas University, Rozzano (Milano), Italy, ⁹SC Gastroenterologia Ospedale Brotzu, Cagliari, Italy, ¹⁰University of Genoa, Policlinico San Martino Department of internal medicine, Genova, Italy, ¹¹UOC Gastroenterologia AOU Mater Domini, Catanzaro, Italy, ¹²Divisione di Gastroenterologia, Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Roma, Italy, ¹³UOC Gastroenterologia Ospedale San Nicola Pellegrino, Trani, Italy, ¹⁴Department of New Technologies and Translational Research in Medicine and Surgery, University of Pisa, Pisa, Italy, ¹⁵Dipartimento di scienze chirurgiche, oncologiche e gastroenterologiche Università di Padova, Padova, Italy, ¹⁶Ospedale S. Filippo Neri, IBD Unit, Roma, Italy

¹Erasmus MC, University Medical Center, Gastroenterology and hepatology, Rotterdam, The Netherlands, ²Erasmus MC, University Medical Center, Public Health, Rotterdam, The Netherlands, ³Maastricht University Medical Center, Gastroenterology and Hepatology, Maastricht, The Netherlands, ⁴Radboud University Medical Center, Gastroenterology and Hepatology, Nijmegen, The Netherlands, ⁵VU University Medical Center, Gastroenterology and Hepatology, Amsterdam, The Netherlands, ⁶University Medical Center Utrecht, Gastroenterology and Hepatology, Utrecht, The Netherlands, ⁷Leiden University Medical Center, Gastroenterology and Hepatology, Leiden, The Netherlands, ⁸Academic Medical Center, Gastroenterology and Hepatology, Amsterdam, The Netherlands, ⁹University Medical Center Groningen, Gastroenterology and Hepatology, Groningen, The Netherlands, ¹⁰Erasmus MC, University Medical Center, Pathology, Rotterdam, The Netherlands, ¹¹Erasmus MC, University Medical Center, Gynaecologic Oncology, Rotterdam, The Netherlands, ¹²PALGA, the nationwide network and registry of histo- and cytopathology in the Netherlands, Houten, The Netherlands

¹Shaare Zedek Medical Center, The Juliet Keidan Institute of Paediatric Gastroenterology and Nutrition, Jerusalem, Israel, ²The Hebrew University- Hadassah Medical Center, Braun School of Public and Community Medicine, Jerusalem, Israel, ³Clalit Health Services, Clalit Research Institute, Chief’s Office, Tel Aviv, Israel, ⁴Maccabi Healthcare Services, Tel Aviv, Israel, ⁵Meuhedet Health Services, Tel Aviv, Israel, ⁶Leumit Health Services, Tel Aviv, Israel, ⁷Rambam Health Care Campus, Department of Gastroenterology, Haifa, Israel, ⁸Chaim Sheba Medical Center, Department of Gastroenterology, Tel Hashomer, Israel, ⁹Faculty of Health Sciences,Ben-Gurion University of the Negev, Department of Gastroenterology and Hepatology, Beer Sheva, Israel, ¹⁰Rabin Medical Center, Division of Gastroenterology, Petah Tivka, Israel, ¹¹Hadassah Medical Center, Hebrew University, Institute of Gastroenterology and Liver Diseases, Jerusalem, Israel

¹Hospital Beatriz Ângelo, Gastroenterology, Loures, Portugal, ²Farncombe Family Digestive Health Research Institute, Ontario, Canada, ³Faculty of Medicina of Lisbon, Lisboa, Portugal

¹Beth Israel Deaconess Medical Center, Harvard Medical School, Division of Gastroenterology and Hepatology, Boston, USA, ²Stanford University School of Medicine, Division of Gastroenterology and Hepatology, Stanford, USA, ³Herlev Hospital, University of Copenhagen, Department of Gastroenterology, Copenhagen, Denmark

¹Samsung Medical Center, Seoul, South Korea

¹GlaxoSmithKline, Value Evidence and Outcomes, Collegeville, USA, ²GlaxoSmithKline, Value Evidence and Outcomes, Stevenage, UK, ³Adelphi Real World, Macclesfield, UK

¹Hospital Universitario de La Princesa, ISS-IP, Universidad Autónoma de Madrid and CIBEREHD, Gastroenterology Unit, Madrid, Spain, ²Hospital Universitario Clínico de Santiago, Gastroenterology Unit, Santiago de Compostela, Spain, ³Hospital Universitario Reina Sofía and IMIBIC, Gastroenterology Unit, Córdoba, Spain, ⁴Hospital Universitario de Galdakao, Gastroenterology Unit, Galdakao, Spain, ⁵Hospital Universitario de Gran Canaria Doctor Negrín, Gastroenterology Unit, Las Palmas de Gran Canaria, Spain, ⁶Mutua Terrasa, Gastroenterology Unit, Tarrasa, Spain, ⁷Hospital San Pedro, Gastroenterology Unit, Logroño, Spain, ⁸Hospital Universitario Son Espases, Gastroenterology Unit, Palma de Mallorca, Spain, ⁹Hospital Lozano Blesa, IIS Aragón and CIBERehd, Gastroenterology Unit, Zaragoza, Spain, ¹⁰Hospital General Universitario de Ciudad Real, Gastroenterology Unit, Ciudad Real, Spain, ¹¹Hospital Universitario y Politécnico de La Fe and CIBEREHD, Gastroenterology Unit, Valencia, Spain, ¹²Hospital Universitario Central de Asturias, Gastroenterology Unit, Oviedo, Spain, ¹³Hospital Universitario Marqués de Valdecilla, Gastroenterology Unit, Santander, Spain, ¹⁴Hospital San Pedro de Alcántara, Gastroenterology Unit, Cáceres, Spain, ¹⁵Complejo Hospitalario de Navarra, Gastroenterology Unit, Pamplona, Spain, ¹⁶Hospital Universitario de Burgos, Gastroenterology Unit, Burgos, Spain, ¹⁷Hospital General Universitario Morales Meseguer, Gastroenterology Unit, Murcia, Spain, ¹⁸Universidad Autónoma de Madrid/IdiPaz and CIBERESP, Department of Preventive Medicine and Public Health, Madrid, Spain

¹Amsterdam UMC, Department of Surgery and Gastroenterology, Amsterdam, The Netherlands, ²Spaarne Gasthuis, Department of Internal medicine, Hoofddorp, The Netherlands, ³Amsterdam UMC, Clinical Research Unit, Amsterdam, The Netherlands, ⁴Amsterdam UMC, Department of Surgery, Amsterdam, The Netherlands

¹Singapore General Hospital, Gastroenterology, Singapore, Singapore, ²Duke-NUS Medical School, Singapore, Singapore, ³SengKang General Hospital, Singapore, Singapore

¹Janssen Immunology, Birkerød, Denmark, ²Janssen Immunology, High Wycombe, UK, ³Incentive, Holte, Denmark, ⁴Leo Pharma, Ballerup, Denmark, ⁵North Zealand University Hospital, Frederikssund, Denmark, ⁶Odense University Hospital, Odense, Denmark

¹University Hospital Zurich, Gastroenterology and Hepatology, Zurich, Switzerland, ²University of Lausanne, Institute of Social and Preventive Medicine, Lausanne, Switzerland, ³Center of Gastroenterology Klinik Hirslanden, Zurich, Switzerland, ⁴Gastroenterology Bethanien, Zurich, Switzerland, ⁵Center of Gastroenterology and Hepatology, Zurich, Zurich, Switzerland, ⁶University of Lausanne, Lausanne, Switzerland, ⁷University Hospital Zurich, Department of Medical Oncology and Hematology, Zurich, Switzerland, ⁸Inselspital Bern University Hospital, Department of Visceral Surgery and Medicine, Bern, Switzerland, ⁹University Hospital Zurich, Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, Zurich, Switzerland

¹Eli Lilly and Company, Indianapolis, USA

¹Evangelismos General Hospital of Athens, Gastroenterology Department, Athens, Greece, ²University Hospital of Heraklion, Gastroenterology Department, Heraklion, Greece, ³First Cardiology Clinic, School of Medicine, University of Athens, Athens, Greece, ⁴School of Health Science and Education, Harokopio University, Athens, Greece

¹Seoul National University College of Medicine, Department of Internal Medicine and Liver Research Institute, Seoul, South Korea, ²The Catholic University of Korea College of Medicine, Department of Medical Statistics, Seoul, South Korea

¹Azienda Ospedaliero Universitaria Pisana, Department of Surgery and Gastroenterology, Pisa, Italy, ²Istituto di Tecnologie Biomediche, CNR, Pisa, Italy, ³University of Pisa, Department of New Technologies and Translational Research in Medicine and Surgery, Pisa, Italy

¹Shaare Tzedek Medical Center, The Juliet Keiden Institute of Pediatric Gastroenterology and Nutrition, Jerusalem, Israel, ²Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel, Department of Gastroenterology and Hepatology, Beer Sheva, Israel, ³The Hebrew University- Hadassah Medical Center, Unit of Epidemiology, Jerusalem, Israel, ⁴Clalit Research Institute, Chief’s Office, Clalit Health Services, Tel-Aviv, Israel, ⁵Maccabi Healthcare Services, Tel-Aviv, Israel, ⁶Meuhedet Health Services, Tel-Aviv, Israel, ⁷Leumit Health Services, Tel-Aviv, Israel, ⁸Icahn Institute for Genomics and Multiscale Biology at Mount Sinai, Department of Genetics and Genomics, New York City, Israel

¹Hospital Universitario Gregorio Marañón, Gastroenterology, Madrid, Spain, ²Hospital Universitari Vall d'Hebron, Crohn-Colitis Care Unit, Barcelona, Spain, ³Elche University Hospital, Gastroenterology, Elche, Spain, ⁴Medical Affairs, Merck Sharp and Dohme, Madrid, Spain, ⁵Medical Affairs, Merck Sharp and Dohme, Spain, Madrid, Spain

¹IBD Unit, "Villa Sofia-Cervello" Hospital, Palermo, Italy, ²Department of Sciences for Health Promotion ‘ G. D’Alessandro’, University of Palermo, Palermo, Italy, ³Gastroenterology of Pediatric Unit, Maggiore Hospital, Bologna, Italy, ⁴Infectious Disease Unit, Department of Biomedical and Clinical Sciences, ‘Luigi Sacco’ University Hospital, Milan, Italy, ⁵IBD Unit, Presidio Columbus Fondazione Policlinico Universitario A. Gemelli IRCCS - Università Cattolica del Sacro Cuore, Rome, Italy, ⁶Department of Biochemical and Clinical Science "L. Sacco" - University of Milan, ASST Fatebenefratelli Sacco, Milan, Italy