¹Cambridge Institute for Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre- University of Cambridge, Cambridge, UK, ²University of Cambridge, Department of Medicine, Cambridge, UK, ³PredictImmune Ltd, Babraham Research Campus, Cambridge, UK

Department of Gastroenterology, Hospital Universitario La Paz, Madrid, Spain

¹Department of Gastroenterology, East Kent Hospitals NHS Foundation Trust, Margate, UK, ²Department of Gastroenterology, East Kent Hospitals NHS Foundation Trust, Canterbury, UK, ³Department of Gastroenterology, East Kent Hospitals NHS Foundation Trust, Ashford, UK

¹Department of Medical School, University of Sheffield, Sheffield, UK, ²Department of General Surgery, Northern General Hospital, Sheffield, UK, ³School of Social Sciences, Leeds Beckett University, Leeds, UK, ⁴Academic Department of Gastroenterology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

¹Gastroenterology Department, Hospital La Fe, Valencia, Spain, ²Physiotherapy Department, University of Valencia, Valencia, Spain, ³Confederación de Asociaciones de Enfermos de Crohn y Colitis Ulcerosa de España, Confederación de Asociaciones de Enfermos de Crohn y Colitis Ulcerosa de España, Madrid, Spain

¹Gastrounit- Medical Division, Copenhagen University Hospital, Hvidovre, Denmark, ²Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

The Sainte-Justine University Hospital Centre, Department of Pediatric Gastroenterology, Montréal, Canada

¹Division of Gastroenterology, Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto HCFMRP, Medicine, Ribeirão Preto, Brazil, ²Division of Coloproctology, Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto HCFMRP, Surgery and Anatomy, Surgery and Anatomy, Brazil

¹Department of Nutrition and Dietetics, Gangnam Severance Hospital, Seoul, Korea Republic of, ²Department of Internal Medicine, Gangnam Severance Hospital, Seoul, Korea Republic of, ³Department of Internal Medicine, Severance Hospital, Seoul, Korea Republic of

North-Western State Medical University n.a. I.I.Mechnikov, the Chair of the Propedeutics of Internal Diseases, Gastroenterology and Dietology n.a. S.M. Riss, Saint Petersburg, Russian Federation

¹Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Republic of, ²Department of Medical Statistics, The Catholic University of Korea College of Medicine, Seoul, Korea Republic of, ³Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea Republic of

¹Ben-Gurion University of the Negev, Social Work, Beer Sheva, Israel, ²Soroka Medical center, Gastroenterology, Beer Sheva, Israel, ³Ben-Gurion University of the Negev, Public Health, Beer Sheva, Israel, ⁴Ben-Gurion University of the Negev, Microbiology and Immunology, Beer Sheva, Israel, ⁵Ben-Gurion University of the Negev, Health Systems Management, Beer Sheva, Israel, ⁶Ben-Gurion University of the Negev, Health Sciences, Metar, Israel

¹St Mark’s Hospital, Wolfson Endoscopy Unit, London, UK, ²Imperial College London, Cancer and Surgery Division, London, UK, ³Stats Consultancy, Stats Consultancy, Amersham, UK, ⁴St Mark’s Hospital, Inflammatory Bowel Diseases Unit, London, UK, ⁵St Mark’s Hospital, Department colorectal surgery, London, UK

¹Departement of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium, ²Department of Gastroenterology, Imelda General Hospital Bonheiden,Bonheiden, Belgium, ³Departement of Pathology, University Hospitals Leuven, Leuven, Belgium, ⁴Medical Imaging Research Center, University Hospitals Leuven, Leuven, Belgium

¹Centro Hospitalar Vila Nova de Gaia e Espinho, Gastroenterology, Vila Nova Gaia, Portugal, ²Centro Hospitalar Vila Nova de Gaia/Espinho, Gastroenterology, Vila Nova de Gaia, Portugal, ³Centro Hospitalar de Vila Nova de Gaia e Espinho, Gastroenterology, Vila Nova de Gaia, Portugal

¹Centre for Colorectal Disease, St Vincent’s University Hospital and School of Medicine- University College Dublin, Dublin, Ireland, ²UCD Obstetrics and Gynaecology Department, School of Medicine, University College Dublin, National Maternity Hospital, Dublin, Ireland

¹Nuffield Department of Medicine, University of Oxford, Translational Gastroenterology Unit, Oxford, UK, ²Clatterbridge Cancer Centre, Oncology, Liverpool, UK, ³Royal Liverpool University Hospital, Gastroenterology, Liverpool, UK, ⁴John Radcliffe Hospital, Cellular Pathology, Oxford, UK, ⁵Institute of Translational Medicine, University of Liverpool, Molecular and Clinical Pharmacology, Liverpool, UK, ⁶Oxford Cancer Centre, Medical Oncology, Oxford, UK

¹Humanitas Research Hospital, IBD Center- Gastroenterology, Rozzano, Italy, ²Inserm U954 Nancy University Hospital, IBD Unit, Nancy, France

¹Asan Medical Center, Gastroenterology, Seoul, Korea Republic of, ²Asan Medical Center, Clinical Epidemiology and Biostatistics, Seoul, Korea Republic of

¹Department of General Surgery, New Cross Hospital, Wolverhampton, UK, ²Department of General Surgery, Academic Foundation Trainee, Wolverhampton, UK