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P541: Real-life effectiveness of ustekinumab in inflammatory bowel disease patients with concomitant psoriasis or psoriatic arthritis: an IG-IBD study

ECCO '19 Copenhagen

Year: 2019
Authors:

D. Pugliese*1, M. Daperno2, G. Fiorino3, E. Savarino4, E. Mosso5, L. Biancone6, A. Testa7, L. Sarpi8, M. Cappello9, G. Bodini10, F. Caprioli11, S. Festa12, G. Laino13, G. Maconi14, S. Mazzuoli15, G. Mocci16, A. Sartini17, A. D'Amore18, S. Alivernini19, E. Gremese19, A. Armuzzi20

1Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, OU IBD Presidio Columbus, Rome, Italy, 2A.O. Ordine Mauriziano, Gastroenterology Unit, Turin, Italy, 3Humanitas Research Hospital, IBD Center, Department of Gastroenterology, Rozzano, Italy, 4University of Padua, Gastroenterology Unit, Department Surgery, Oncology and Gastroenterology, Padua, Italy, 5General and Specialistic Medicine/Gastroenterology, Città della Salute e della Scienza di Torino, Turin, Italy, 6University of Rome Tor Vergata, Department of Systems Medicine, Gastroenterology, Rome, Italy, 7Federico II University, Gastroenterology, Naples, Italy, 8Gastroenterologia ed Endoscopia Digestiva Aziendale USL Umbria1, Perugia, Italy, 9Gastroenterology and Hepatology Section, DiBiMis, Palermo, Italy, 10University of Genoa, Gastrointestinal Unit, Department of Internal Medicine, Genoa, Italy, 11Department of Pathophysiology and Transplantation, University of Milan and Gastroenterology and Endoscopy Unit, IRCCS Cà Granda, IRCCS Policlinico Hospital, Milan, Italy, 12San Filippo Neri Hospital, IBD Unit, Rome, Italy, 13Department of New Technologies and Translational Research in Medicine and Surgery, Pisa, Italy, 14Luigi Sacco University Hospital, Gastroenterology and IBD Unit, Milan, Italy, 15San Nicola Pellegrino Hospital, Gastroenterology Unit, Trani, Italy, 16‘Brotzu’ Hospital, Division of Gastroenterology, Cagliari, Italy, 17University of Modena and Reggio Emilia, Department of Internal Medicine, Gastroenterology Unit, Modena, Italy, 18Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, Department of Dermatology, Rome, Italy, 19Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, Division of Rheumatology, Rome, Italy, 20OU IBD Presidio Columbus, Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, Rome, Italy

P542: Efficacy and safety of biological therapies in chronic antibiotic-refractory pouchitis: a retrospective single-centre experience

ECCO '19 Copenhagen

Year: 2019
Authors:

B. Verstockt*1,2, C. Claeys1, G. Van Assche1,2, A. D'Hoore3, A. Wolthuis3, S. Vermeire1,2, M. Ferrante1,2

1University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, 2KU Leuven, Department of Chronic Diseases, Metabolism and Ageing, Translational Research Center for Gastrointestinal Disorders (TARGID), Leuven, Belgium, 3University Hospitals Leuven, Department of Abdominal surgery, Leuven, Belgium

P543: Seven-year efficacy and safety of azathioprine treatment in the maintenance of steroid-free remission in inflammatory bowel disease patients

ECCO '19 Copenhagen

Year: 2019
Authors:

C. Cassieri*1, R. Pica2, E. V. Avallone1, G. Brandimarte3, M. Zippi2, P. Crispino1, D. De Nitto2, P. G. Lecca3, P. Vernia1, P. Paoluzi1, E. S. Corazziari1

1Sapienza University, Internal Medicine and Medical Specialties, Rome, Italy, 2Sandro Pertini Hospital, Unit of Gastroenterology and Digestive Endoscopy, Rome, Italy, 3’Cristo Re’ Hospital, Internal Medicine, Rome, Italy

P544: Impact of patient education on switch acceptance in IBD patients in remission, with infliximab originator switched for an infliximab biosimilar: a prospective study

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Hastier-De Chelle*1, V. Cluzeau1, J. Condat1, N. Arab1, X. Hébuterne1, J. Filippi1

1Hôpital Archet 2, Alpes-Maritimes, Nice, France

P545: Elderly patients with inflammatory bowel disease (IBD) are less likely to persist on anti-TNF therapy compared with younger patients: data from the Sicilian Network for Inflammatory Bowel Diseases (SN-IBD)

ECCO '19 Copenhagen

Year: 2019
Authors:

S. Porcari1, O. Fidanza1, A. Alibrandi2, S. Renna3, M. Cappello4, S. Siringo5, A. Privitera6, G. Inserra7, F. Mocciaro8, G. Magri9, A. Carroccio10, N. Belluardo11, C. Bertolami12, S. Garufi13, M. Ventimiglia3, F. Macaluso3, A. Viola1, M. Cottone15, A. Orlando3, W. Fries*16

1Inflammatory Bowel Disease Unit, A.O.U. Policlinico ‘G. Martino’, Messina, Italy, 2University of Messina, Department of Economics, Unit of Statistical and Mathematical Sciences, messina, Italy, 3Inflammatory bowel disease Unit, A.O.O.R. ‘Villa Sofia-Cervello’, Palermo, Italy, 4Gastroenterology and Hepatology Unit, A.O.U. Policlinico ‘G. Giaccone’, Palermo, Italy, 5Gastroenterology Unit, A.R.N.A.S. ‘Garibaldi’, Catania, Italy, 6Inflammatory Bowel Disease Unit, A.O. ‘Cannizzaro’, Catania, Italy, 7Internal Medicine Unit, A.O.U. Policlinico ‘Vittorio Emanuele’, Catania, Italy, 8Gastroenterology and Endoscopy Unit, A.R.N.A.S. ‘Civico Di Cristina Benfratelli’, Palermo, Italy, 9Gastroenterology Unit, A.O. ‘Santa Marta e S. Venera’, Acireale (CT), Italy, 10Internal Medicine Unit, A.O. ‘Giovanni Paolo II’, Sciacca (AG), Italy, 11Gastroenterology Unit, A.O. ‘Guzzardi’, Vittoria (RG), Italy, 12Gastroenterology Unit, A.O.O.R. ‘Papardo Piemonte’, Messina, Italy, 13Gastroenterology Unit, A.O.O.R. ‘S. Elia- M. Raimondi’, Caltanissetta, Italy, 15Inflammatory Bowel Disease Unit, A.O.O.R. ‘Villa Sofia-Cervello’, Messina, Italy, 16University of Messina, Department of Clinical and Experimental Medicine, Messina, Italy

P546: Therapeutic drug monitoring of vedolizumab in inflammatory bowel disease

ECCO '19 Copenhagen

Year: 2019
Authors:

N. Torres1, D. Martín Arranz2, M. Sánchez Azofra2, E. Martín Arranz2, L. Garcia2, P. Nozal3, J. Pascual1, I. Apraiz1, M. López1, D. Arteta1, D. Nagore*1

1Progenika Biopharma, S.A, A Grifols company, Derio, Spain, 2Unidad de Enfermedad Inflamatoria Intestinal Hospital Universitario La Paz, Madrid, Spain, 3Unidad de Inmunología, Madrid, Spain

P547: Distribution of mesenteric macrophage polarisation: a guide for surgical resections in Crohn’s disease?

ECCO '19 Copenhagen

Year: 2019
Authors:

J. van der Meer*1, K. Wasmann2, J. van der Bilt3, M. Becker1, W. Bemelman2, M. Wildenberg1,4, C. Buskens2

1Amsterdam UMC, Tytgat Institute for Liver and Intestinal Research, Amsterdam, The Netherlands, 2Amsterdam UMC, Department of Surgery, Amsterdam, The Netherlands, 3Flevoziekenhuis, Department of Surgery, Almere, The Netherlands, 4Amsterdam UMC, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands

P548: Vedolizumab clinical decision support tool predicts hospitalisation, surgery, and healthcare resource utilisation

ECCO '19 Copenhagen

Year: 2019
Authors:

P. S. Dulai*1, Z. Huang2, Y. Wan2, M. Luo2

1University of California San Diego, La Jolla, CA, USA, 2Takeda Pharmaceuticals U.S.A., Inc., Deerfield, IL, USA

P549: Vitamin D deficiency as a part of extraintestinal manifestations in IBD Patients: a single-centre experience

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Georgieva*1, A. Atanassova1, D. Gerova2, M. Todorova2

1Medical University Varna, Clinic of Hepatogastroenterology, St. Marina University Hospital, Vаrna, Bulgaria, 2Medical University Varna, Department of General Medicine and Clinical Laboratory, Varna, Bulgaria

P550: Anti-mycobacterium paratuberculous therapy in Crohn’s disease: outcomes from tertiary IBD referral centres

ECCO '19 Copenhagen

Year: 2019
Authors:

E. Johnston*1, S. Honap1, B. Al-Hakim1, J. Sanderson1

1Guy's and St. Thomas' Hospitals NHS Foundation Trust, Gastroenterology, London, UK

P551: Use of preoperative total parenteral nutrition is associated with clinical and laboratory remission in severe active Crohn’s disease

ECCO '19 Copenhagen

Year: 2019
Authors:

N. Kolonimos*1,2, M. S. Berns1,2, L. Hai Katvan1,2, M. Zelcer1,2, O. A. Hatoum2,3, N. Sakran2,3, I. M. Gralnek1,2, E. Zittan1,2

1HaEmek Medical Center, Ellen and Pinchas Mamber Institute of Gastroenterology and Liver Diseases and the Center for IBD, Afula, Israel, 2Technion-Israel Institute of Technology, Rappaport Faculty of Medicine, Haifa, Israel, 3HaEmek Medical Center, Department of Surgery, Afula, Israel

P552: Gastroenterologists’ perceptions on use of medical cannabis for IBD

ECCO '19 Copenhagen

Year: 2019
Authors:

B. Koslowsky*1, A. Bar-Gil Shitrit1, E. Goldin1, B. Mazuz1

1Shaare-Zedek Medical Center, Digestive Diseases Institute, Jerusalem, Israel

P553: Efficacy, safety and cost-efficiency of adalimumab 80 mg every other week in previously intensified IBD patients under treatment with adalimumab 40 mg every week

ECCO '19 Copenhagen

Year: 2019
Authors:

R. Ferreiro-Iglesias*1, A. Jardi1, A. Quiroga1, I. Baston1, J. Gonzalez2, J. M. Giraldez2, I. Zarra2, M. J. Lamas2, J. E. Dominguez-Munoz1, M. Barreiro-de Acosta1

1University Hospital, Gastroenterology, Santiago de Compostela, Spain, 2University Hospital, Pharmacy, Santiago de Compostela, Spain

P554: Point of Care detection of anti-infliximab antibodies in inflammatory bowel disease patients treated with the biosimilar SB2: performance comparison with ELISA

ECCO '19 Copenhagen

Year: 2019
Authors:

R. Atreya1, H. Schmitt1, S. Fischer1, M. F. Neurath1, X. Rekalde2, D. Nagore*2, A. Ametzazurra2

1Friedrich-Alexander-University Erlangen-Nürnberg, Medical Department I, Erlangen, Germany, 2Progenika Biopharma, R&D, Derio, Spain

P555: Deep remission and mucosal healing in IBD patients under immunosuppression with azathioprine and 6-mercaptopurine

ECCO '19 Copenhagen

Year: 2019
Authors:

J. C. Silva*1, A. P. Silva1, A. Rodrigues1, C. Fernandes1, A. Ponte1, J. Rodrigues1, M. Sousa1, A. C. Gomes1, J. Carvalho1

1Centro Hospitalar Vila Nova de Gaia/Espinho, Gastroenterology, Vila Nova de Gaia, Portugal

P556: The prevalence of metabolic bone disease in patients with IBD- preliminary results from POLIBD study

ECCO '19 Copenhagen

Year: 2019
Authors:

J. Sztembis1, D. Piątek2, S. Jarmakiewicz3, P. R. Kiela4, R. Filip*5,6

1Clinical Hospital No. 2, Department of Internal Medicine and Endocrinology, Rzeszow, Poland, 2Medical University of Lublin, Chair and Departament of Conservative Dentistry with Endodontics, Lublin, Poland, 3University of Rzeszów, Poland, Faculty of Medicine, Rzeszów, Poland, 4Steele Children's Research Center, Departament of Pediatrics and Immunology, Tucson, USA, 5Clinical Hospital No. 2 Rzeszow, Departament of Gastroenterology with IBD Unit, Rzeszów, Poland, 6University of Rzeszów, Faculty of Medicine, Rzeszów, Poland

P557: Sustained remission in inflammatory bowel disease patients after discontinuing infliximab; the ongoing reluctance to stop biologics

ECCO '19 Copenhagen

Year: 2019
Authors:

T. Ryan*1, L. Coffey1, A. Mullen1, J. Leyden1, P. MacMathuna1

1Mater Misericordiae University Hospital, Gastroenterology, Dublin, Ireland

P558: Iterative ileocolonic resection for Crohn’s disease: a prospective multi-centric cohort study of the GETAID Chirurgie

ECCO '19 Copenhagen

Year: 2019
Authors:

S. Abdalla1, A. Brouquet2, L. Maggiori3, P. Zerbib4, Q. Denost5, A. Germain6, E. Cotte7, L. Beyer-Berjot8, N. Munoz-Bongrand9, V. Desfourneaux10, A. Rahili11, J-P. Duffas12, K. Pautrat13, C. Denet14, V. Bridoux15, G. Meurette16, J-L. Faucheron17, J. Loriau18, F. Guillon19, E. Vicaut20, S. Benoist2, Y. Panis3, J. Lefevre*1

1Hopital saint antoine, General and Digestive surgery, Paris, France, 2CHU Bicètre, General and Digestive surgery, Le Kremlin-Bicètre, France, 3CHU Beaujon, Colorectal Surgery, Clichy, France, 4CHRU Lille, General Surgery, Lille, France, 5CHU Pessac, Colorectal Surgery, Bordeaux, France, 6CHU Nancy, General and Digestive surgery, Nancy, France, 7CHU Lyon-Sud, General and Digestive surgery, Lyon, France, 8CHU Nord, General and Digestive surgery, Marseille, France, 9CHU St-Louis, General and Digestive surgery, Paris, France, 10CHU Rennes, General and Digestive surgery, Rennes, France, 11CHU Nice, General and Digestive surgery, Nice, France, 12CHU Rangueil, General and Digestive surgery, Toulouse, France, 13CHU Lariboisière, General and Digestive surgery, Paris, France, 14Institut Monsouris, General and Digestive surgery, Paris, France, 15CHRU Rouen, General and Digestive surgery, Rouen, France, 16CHU Nantes, General and Digestive surgery, Nantes, France, 17CHU Grenoble, General and Digestive surgery, Grenoble, France, 18Hopital Saint-Jospeh, General and Digestive surgery, Paris, France, 19CHRU Montpellier, General and Digestive surgery, Montpellier, France, 20URC Fernand-Widal, Unité de Recherche clinique, Paris, France

P559: Real-life experience with long-term maintenance of golimumab in ulcerative colitis patients

ECCO '19 Copenhagen

Year: 2019
Authors:

M. Iborra*1, N. García-Morales1, S. Rubio2, O. Nantes Castillejo2, F. Bertoletti3, E. García-Planella3, M. Calvo4, I. Vera4, C. Taxonera5, C. Alba5, M. Boscá-Watts6, D. Martí-Aguado6, M. P. Ballester Ferrer6, M. Sierra7, N. Cano-Sanz7, N. Mancenido8, R. Pajares-Villarroya8, B. Beltrán1, A. Cañada9, P. Nos1

1Hospital Universitario y Politécnico La Fe, Gastroenterology, Valencia, Spain, 2Complejo Hospitalario de Navarra, Gastroenterology, Pamplona, Spain, 3Hospital de la Santa Creu i Sant Pau, Gastroenterology, Barcelona, Spain, 4Hospital Universitario Clínica Puerta de Hierro, Gastroenterology, Madrid, Spain, 5Hospital Clínico San Carlos, Gastroenterology, Madrid, Spain, 6Hospital Clínico Universitario, Gastroenterology, Valencia, Spain, 7Complejo Asistencial Universitario de León, Gastroenterology, León, Spain, 8Hospital Infanta Sofía, San Sebastián de los Reyes, Gastroenterology, Madrid, Spain, 9Hospital Universitario y Politécnico La Fe, Biostatistics and Bioinformatics, Valencia, Spain

P560: Multi-centric randomised study comparing interventional vs. non-interventional treatment for anal fistulas in patient with Crohn’s disease and adalimumab treatment

ECCO '19 Copenhagen

Year: 2019
Authors:

L. Abramowitz1, D. Bouchard2, L. Siproudhis3, F. Pigot*2, P. Roumeguere-Blond4, H. Pillant5, B. Vinson-Bonnet6, J-L. Faucheron7, A. Senejoux8, G. Bonnaud9, G. Meurette10, C. Train11, G. Staumont12

1Chu Bichat, Proctologie, Paris, France, 2Hopital Bagatelle, Proctologie, Bordeaux, France, 3Chu Rennes, Gastroenterologie, Rennes, France, 4Clinique Tivoli, Proctologie, Bordeaux, France, 5Hopital Saint Joseph, Proctologie, Paris, France, 6Ch Poissy, Chirurgie Digestive, Poissy, France, 7Chu Grenoble, Chirurgie Digestive, Grenoble, France, 8Clinique Saint Gregoire, Proctologie, Saint Gregoire, France, 9clinique Ambroise Pare, Gastroenterologie, Toulouse, France, 10Chu Nantes, Chirurgie Digestive, Nantes, France, 11Clinsearch, Statistiques, Bagneux, France, 12Clinique Saint Jean, Gastroenterologie, Toulouse, France