¹CHU Estaing, Department of Digestive and Hepatobiliary Medicine- Department of Gastroenterology, Clermont-Ferrand, France, ²CHU Lyon-Sud, Gastroenterology, Lyon, France, ³Fondazione Policlinico A. Gemelli IRCCS- Rome- Italy, IBD Unit Presidio Columbus, Rome, Italy, ⁴Helsinki University Hospital- Meilahti Hospital, Hus, Helsinski, Finland, ⁵Federal University of São Paulo–UNIFESP-, Gastroenterology, Sao Paulo, Brazil, ⁶CHU, Biostatistics unit, Clermont-Ferrand, France

¹Lebanese university- school of medecine, Gastroenterology, Beirut, Lebanon, ²Lebanese university- school of medecine, Gastroenterology, Hadath, Lebanon, ³Lebanese university- school of medecine, Internal medecine, Hadath, Lebanon, ⁴Lebanese uniiversity- school of medecine, internal medecine, Hadath, Lebanon

¹IRCCS Sacro Cuore Don Calabria Hospital- Negrar-, Department of Pathology, Negrar, Italy, ²Mt Sinai Hospital, Pathology-, Toronto, Canada, ³IRCCS Sacro Cuore Don Calabria Hospital- Negrar, Medicine, Verona, Italy, ⁴IRCCS Sacro Cuore Don Calabria Hospital- Negrar, Clinical Pathology, Verona, Italy, ⁵IRCCS Sacro Cuore Don Calabria Hospital- Negrar, Pathology, Verona, Italy, ⁶Mt Sinai Hospital, Pathology, Toronto, Canada

¹Federico II University of Naples, Department of Clinical Medicine- Gastroenterology and Surgery, Naples, Italy, ²Infective Diseases Unit- School of Medicine Federico II of Naples, Department of Clinical Medicine and Surgery, Naples, Italy

¹Clinical Hospital Centre Zagreb, Department of Gastroenterology and Hepatology, Zagreb, Croatia, ²Zagreb School of Medicine, Department of Gastroenterology and Hepatology, Zagreb, Croatia, ³Zagreb School of Medicine, University of Zagreb, Zagreb, Croatia, ⁴Unit for Clinical Nutrition, Department of Gastroenterology and Hepatology, Zagreb, Croatia, ⁵Clinical Hospital Merkur, Department of Gastroenterology and Hepatology, Zagreb, Croatia, ⁶School of Medicine Rijeka, University of Rijeka, Rijeka, Croatia

¹ASST Papa Giovanni XXIII, Pediatric Hepatology Gastroenterology and Transplatation, Bergamo, Italy, ²ASST Papa Giovanni XXIII, FROM Research Foundation, Bergamo, Italy, ³G. Gaslini Institute - IRCCS, Gastroenterology- Digestive Endoscopy and Nutrition Unit, Genova, Italy, ⁴Institute of Child and Maternal Health - IRCCS ‘Burlo Garofolo’, Institute of Child and Maternal Health - IRCCS ‘Burlo Garofolo’, Trieste, Italy, ⁵marco.deganello@gmail.com, Pediatric Department, Verona, Italy, ⁶Sapienza University of Rome- Sant’Andrea University Hospital, Pediatrics- NESMOS Department- School of Medicine and Psychology, Rome, Italy, ⁷’S. Spirito’ Hospital, Pediatric Gastroenterology and Endoscopy Unit, Pescara, Italy, ⁸University of Naples ‘Federico II’, Department of Translational Medical Science- Section of Pediatrics, Naples, Italy, ⁹’Mayer’ Hospital, Pediatric Gastroenterology and Endoscopy Unit, Florence, Italy, ¹⁰University of Messina, Pediatric Gastroenterology and Cystic Fibrosis Unit, Messina, Italy, ¹¹Bambino Gesù Children Hospital- IRCCS, Digestive Endoscopy and Surgery Unit, Rome, Italy, ¹²Mauriziano Hospital Turin, Gastroenterology Unit, Turin, Italy, ¹³Sapienza – University of Rome, Pediatric Gastroenterology and Liver Unit- Maternal and Child Department, Rome, Italy

¹John Hunter Hospital, Gastroenterology, New Lambton, Australia, ²John Hunter Hospital, Radiology, New Lambton, Australia, ³Robarts Clinical Trials Inc., Trials, London, Canada, ⁴The Queen Elizabeth Hospital, Gastroenterology, Adelaide, Australia, ⁵Western University, Gastroenterology, London, Canada

¹University of Bergen, Department of Clinical Medicine, Bergen, Norway, ²Haukeland University Hospital, National Centre for Ultrasound in Gastroenterology, Bergen, Norway

¹Icahn School of Medicine at Mount Sinai, Department of Medicine, New York, USA, ²Icahn School of Medicine at Mount Sinai, Division of Gastroenterology, New York, USA, ³Emory University School of Medicine, Division of Digestive Diseases, Atlanta, USA

¹NIHR Nottingham Digestive Diseases Biomedical Research Centre, Gastroenterology, Nottingham, UK, ²KU Leuven, Chronic Diseases- Metabolism and Ageing- TARGID-IBD Unit, Leuven, Belgium, ³University Hospitals Leuven, Gastroenterology and Hepatology, Leuven, Belgium, ⁴Jagiellonian University Medical College, Department of Paediatrics- Gastroenterology and Nutrition, Krakow, Poland, ⁵Amstedam UMC- VU University Medical Center, Department of Gastroenterology and Hepatology- AG&M Research Institute, Amsterdam, The Netherlands, ⁶University of Ioannina School of Health Sciences, Division of Gastroenterology- Department of Internal Medicine- Faculty of Medicine, Ioannina, Greece, ⁷Venizeleio General Hospital, Department of Gastroenterology, Heraklion, Greece, ⁸Sheba Medical Center- Tel Hashomer, Department of Gastroenterology, Tel Hashomer, Israel, ⁹Tel-Aviv University, Sackler School of Medicine, Tel-Aviv, Israel, ¹⁰Orebro University, Department of Gastroenterology- Faculty of Medicine and Health, Orebro, Sweden, ¹¹University of Szeged, First Department of Medicine, Szeged, Hungary, ¹²Mater Dei Hospital, Department of Medicine- Division of Gastroenterology, Msida, Malta

¹Western University, Department of Medicine and Department of Epidemiology and Biostatistics, London, Canada, ²AbbVie Inc., Health Economics and Outcomes Research, North Chicago, USA, ³AbbVie Inc., Immunology, North Chicago, USA, ⁴AbbVie Inc., Clinical Development, North Chicago, USA, ⁵Adelphi Values, Patient Centered Outcomes, Boston, USA, ⁶Icahn School of Medicine at Mount Sinai, Division of Hematology and Oncology- Department of Medicine and Department of Pathology, New York, USA

Leiden University Medical Centre, Gastroenterology, Leiden, The Netherlands

¹University of Birmingham, Institute of Translational Medicine, Birmingham, UK, ²University of Milan, Gastroenterology, Milan, Italy, ³University of Birmingham, NIHR Biomedical Research Centre, Birmingham, UK, ⁴University of Cologne, Institute for Biological Physics, Cologne, Germany, ⁵University Hospitals Birmingham NHS Foundation Trust, Department of Histopathology, Birmingham, UK, ⁶University of Calgary, IBD Unit, Calgary, Canada

¹Soonchunhyang University College of Medicine, Digestive Disease Center- Institute for Digestive Research, Seoul, Korea- Republic Of, ²Soonchunhyang University College of Medicine, Department of biostatistics, Seoul, Korea- Republic Of

The Chinese University of Hong Kong- Prince of Wales Hospital, Department of Medicine and Therapeutics, Hong Kong, Hong Kong- China

¹Emma Children’s Hospital- Amsterdam UMC- University of Amsterdam, Pediatric Gastroenterology, Amsterdam, The Netherlands, ²Amsterdam UMC- University of Amsterdam, Department of Experimental Immunology, Amsterdam, The Netherlands, ³Amsterdam UMC- University of Amsterdam, Gastroenterology and Hepatology, Amsterdam, The Netherlands

¹Complejo Hospitalario Universitario de Ferrol, Gastroenterology, Ferrol, Spain, ²Complejo Asistencial Universitario de León, Gastroenterology, León, Spain, ³Hospital Universitario Puerta de Hierro, Gastroenterology, Madrid, Spain, ⁴Hospital Universitario Fundación Alcorcón, Gastroenterology, Madrid, Spain, ⁵Hospital Universitario Infanta Cristina, Gastroenterology, Madrid, Spain, ⁶Hospital Universitario y Politécnico de La Fe, Gastroenterology, Valencia, Spain, ⁷Hospital Universitario Marqués de Valdecilla, Gastroenterology, Santander, Spain, ⁸Hospital Universitario Infanta Sofía, Gastroenterology, Madrid, Spain

¹ISCARE I.V.F a.s., Clinical and Research Centre for IBD, Prague, Czech Republic, ²1st Faculty of Medicine- Charles University in Prague, Institute of Pharmacology, Prague, Czech Republic, ³1st Faculty of Medicine and Central Military Hospital, Department of Internal Medicine, Prague, Czech Republic, ⁴GENNET, Laboratory of Immunology, Prague, Czech Republic, ⁵Patient Organisation, Pacienti IBD z.s., Prague, Czech Republic

University Of Chicago Medicine, Inflammatory Bowel Disease Center, Chicago, USA

¹Hadassah-Hebrew University Medical Center, Department of Obstetrics and Gynecology, Jerusalem, Israel, ²Shaare Zedek Medical Center, Department of Obstetrics and Gynecology, Jerusalem, Israel