¹IRCCS Sacro Cuore Don Calabria, IBD Unit, Negrar, Italy, ²University of L'Aquila, Gastroenterology Unit, L'Aquila, Italy, ³IRCCS Sacro Cuore Don Calabria, Pharmacy, Negrar, Italy, ⁴University of Verona, Epidemiology and medical statistics, Verona, Italy, ⁵IRCCS Sacro Cuore Don Calabria, Rheumatology, Negrar, Italy

¹The University of Oslo, Department of Health Management and Health Economics, Oslo, Norway, ²Oslo University Hospital, Department of Gastroenterology, Oslo, Norway

¹National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Immunology and Immunotherapy, Birmingham, UK, ²Institute of Translational Medicine, Gastroenterology, Birmingham, UK, ³University Hospitals Birmingham, Pathology, Birmingham, UK, ⁴University Hospitals Birmingham, Gastroenterology, Birmingham, UK

¹Hospital de Galdakao, Gastroenterology, Galdakao, Spain, ²Hospital Clinic, Gastroenterology, Barcelona, Spain, ³Hospital Universitario Ramón y Cajal, Gastroenterology, Madrid, Spain, ⁴Hospital del Mar, Gastroenterology, Barcelona, Spain, ⁵Hospital Universitario Germans Trias i Pujol, Gastroenterology, Badalona, Spain, ⁶Complejo Hospitalario de Navarra, Gastroenterology, Pamplona, Spain, ⁷Hospital de Cruces, Gastroenterology, Bilbao, Spain, ⁸Hospital Universitario Puerta de Hierro, Gastroenterology, Majadahonda, Spain, ⁹Hospital de la Santa Creu i Sant Pau, Gastroenterology, Barcelona, Spain, ¹⁰Hospital Universitario Miguel Servet, Gastroenterology, Zaragoza, Spain, ¹¹Hospital Universitario de La Princesa, Gastroenterology, Madrid, Spain, ¹²Instituto de Investigación Sanitaria Princesa (IIS-IP) and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain, ¹³Hospital Clínico Universitario de Santiago de Compostela, Gastroenterology, Santiago de Compostela, Spain, ¹⁴Hospital Montecelo, Gastroenterology, Pontevedra, Spain, ¹⁵Hospital Universitario Reina Sofía, Gastroenterology, Córdoba, Spain, ¹⁶IMIBIC, Córdoba, Spain, ¹⁷Hospital Clínico San Carlos, Gastroenterology, Madrid, Spain, ¹⁸Hospital Marqués de Valdecilla, Gastroenterology, Santander, Spain, ¹⁹Hospital Universitario La Paz, Gastroenterology, Madrid, Spain, ²⁰Hospital Son Llàtzer, Gastroenterology, Palma, Spain, ²¹Hospital Universitari Mutua Terrassa, Gastroenterology, Terrassa, Spain, ²²Centro de Investigación biomédica en red de enfermedades hepáticas y digestivas (CIBERehd), Terrassa, Spain, ²³Hospital de Salamanca, Gastroenterology, Salamanca, Spain, ²⁴Hospital Universitario de Girona, Gastroenterology, Girona, Spain, ²⁵Hospital Arnau de Vilanova, Gastroenterology, Lérida, Spain

¹University of Michigan, Ann Arbor, USA, ²Genentech, South San Francisco, USA, ³Roche, Burgess Hill, UK

¹Royal Infirmary of Edinburgh, Edinburgh, UK, ²St Mark's Hospital, Harrow, UK, ³Complejo Hospitalario de Navarra, Navarra, Spain, ⁴Western General Hospital, Edinburgh, UK, ⁵University of Edinburgh, Edinburgh, UK, ⁶University of Oxford, Oxford, UK

¹Saint-Antoine Hospital, Paris, France, ²CH Lyon-Sud, Lyon, France, ³CHU Estaing, Clermont-Ferrand, France, ⁴Yokkaichi Hazu Medical Center, Yokkaichi, Japan, ⁵Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ⁶CHU Nancy, Vandoeuvre Les Nancy, France, ⁷Hopital Beaujon, Clichy, France

¹Kagawa University, Department of Gastroenterology and Neurology , Faculty of Medicine, Takamatsu, Japan, ²Hyogo collage of Medicine, Department of Inflammatory Bowel Disease , Division of surgery, Nishinomiya, Japan

¹University Hospital of Udine, Istituto di Patologia Clinica, Udine, Italy, ²University Hospital of Udine, Dipartimento di Area Medica, Udine, Italy, ³University Hospital of Udine, Gastroenterology, Udine, Italy, ⁴University Hospital of Udine, General Surgery and Transplantation Unit, Udine, Italy, ⁵University Hospital of Udine, Department of Medical and Biological Sciences, Udine, Italy

¹Yokkaichi Hazu Medical Centre, IBD Centre, Yokkaichi, Japan

¹Kyushu University, Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Fukuoka, Japan, ²Kyushu University Hospital, Department of Endoscopic Diagnostics and Therapeutics, Fukuoka, Japan, ³Kyushu University Hospital, International Medical Department, Fukuoka, Japan, ⁴Saga University Hospital, Department of Endoscopic Diagnostic and Therapeutics, Saga, Japan

¹Hospital da Senhora da Oliveira, Gastroenterology, Guimarães, Portugal, ²Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga/Guimarães, Portugal, ³ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal

¹Instituto Português de Oncologia de Lisboa, Gastroenterology, Lisbon, Portugal, ²Jagiellonian University Medical College, Pediatrics, Gastroenterology and Nutrition, Krakow, Poland, ³School of Health Sciences and University Hospital of Ioannina, Gastroenterology, Ioannina, Greece, ⁴Erasmus Medical Center, Gastroenterology and Hepatology, Rotterdam, The Netherlands, ⁵Nanjing University Affiliated Jinling Hospital, Gastroenterology and Hepatology, Nanjing, China, ⁶Gastroenterology Outpatients Clinic, Leipzig, Germany, ⁷Mater Dei Hospital, Medicine, Msida, Malta, ⁸University of Padua, Surgery, Oncology and Gastroenterology – DiSCOG, Padova, Italy, ⁹Hospital Universitario de La Princesa, Gastroenterology, Madrid, Spain, ¹⁰Royal Victoria Infirmary, Gastroenterology, Newcastle Upon Tyne, UK, ¹¹Hospital Prof. Doutor Fernando Fonseca, Gastroenterology, Amadora, Portugal, ¹²Venizeleio General Hospital, Gastroenterology, Heraklion, Greece, ¹³Digestive diseases Institute, Shaare Zedek Medical Center, Jerusalem, Israel, ¹⁴Hospital Universitario de Canarias, Tenerife, Spain

¹McGill University, Gastroenterology, Montreal, Canada, ²University of British Columbia, Gastroenterology, Vancouver, Canada

¹University of New South Wales, Department of Medicine, Sydney, Australia, ²University of New South Wales, Sydney, Australia

¹Southampton Children's Hospital, Department of Paediatric Surgery, Southampton, UK, ²University Hospital Southampton, Department of Human Genetics and Genomic Medicine, Southampton, UK, ³University Hospital Southampton, NIHR Southampton Biomedical Research Centre, Southampton, UK

¹Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil, Surgery and Anatomy, Ribeirão Preto, SP, Brazil, ²Ribeirão Preto Medical School, University of São Paulo, Division of Gastroenterology, Department of Medicine, Ribeirão Preto - SP, Brazil

¹University Hospital, Gastroenterology, Santiago de Compostela, Spain

¹MSD, Luzern, Switzerland, ²Clinique Jules Verne, Paris, France, ³Paracelsus Private Medical University, Salzburg, Austria, ⁴Gastroenterologie, Remscheid, Germany, ⁵Charité Universitätsmedizin, Berlin, Germany, ⁶KU Leuven, Leuven, Belgium, ⁷MSD Italy, Rome, Italy