P670: Identification of two additional susceptibility loci for Crohn's disease in KoreansECCO'21 VirtualYear: 2021
Authors: Lee, H.S.(1);Jung, S.(1);Ye, B.D.(2);Baek, J.(1);Park, D.(1);Park, S.H.(2);Yang, S.K.(2);Song, K.(1);
(1)University of Ulsan College of Medicine- Asan Medical Center, Department of Biochemistry and Molecular Biology, Seoul, Korea- Republic Of;(2)University of Ulsan College of Medicine- Asan Medical Center, Department of Gastroenterology, Seoul, Korea- Republic Of
P671: Effect of genetic polymorphisms in the folate pathway on the efficacy and safety of methotrexate in Crohn’s disease.ECCO'21 VirtualYear: 2021
Authors: Salazar, J.(1);Gordillo Abalos, J.(2);Fernández, A.(3);Esteve, M.(4);Pérez Gisbert, J.(5);Busquets, D.(6);Lucendo, A.(7);Márquez, L.(8);Guardiola, J.(9);Martin, M.D.(10);Iglesias, E.(11);Monfort, D.(12);Villoria, A.(13);Cañete, F.(14);Bell, O.(1);Ricart, E.(3);Zabana, Y.(4);Domènech, E.(14);Garcia-Planella, E.(2);
(1)Hospital de la Santa Creu i Sant Pau, Institut de Recerca, Barcelona, Spain;(2)Hospital de la Santa Creu i Sant Pau, Department of Gastroenterology, Barcelona, Spain;(3)Hospital Clínic i Provincial, Department of Gastroenterology, Barcelona, Spain;(4)Hospital Mútua de Terrassa, Department of Gastroenterology, Terrassa, Spain;(5)Hospital Universitario de La Princesa, Department of Gastroenterology, Madrid, Spain;(6)Hospital Universitari Dr. Josep Trueta, Department of Gastroenterology, Girona, Spain;(7)Hospital General de Tomelloso, Department of Gastroenterology, Ciudad Real, Spain;(8)Hospital del Mar- Institut Hospital del Mar d’investigacions Mèdiques IMIM, Department of Gastroenterology, Barcelona, Spain;(9)Hospital Universitari Bellvitge- IDIBELL, Department of Gastroenterology, L'Hospitalet del Llobregat, Spain;(10)Hospital Unisversitario La Paz, Department of Gastroenterology, Madrid, Spain;(11)Hospital Reina Sofía, Department of Gastroenterology, Córdoba, Spain;(12)Consorci Sanitari de Terrassa, Department of Gastroenterology, Terrassa, Spain;(13)Hospital Universitari Parc Taulí Sabadell, Department of Gastroenterology, Sabadell, Spain;(14)Hospital Universitari Germans Trias i Pujol, Department of Gastroenterology, Badalona, Spain
P672: A tertiary multicenter cohort of patients with chronic intestinal pseudo-obstruction and Crohn’s disease: a rare association with a high prevalence of monogenic disorders.ECCO'21 VirtualYear: 2021
Authors: De Castelbajac, F.(1);Charbit-Henrion, F.(2);Goulet, O.(3);Cerf-Bensussan, N.(4);Treton, X.(1);Stefanescu, C.(1);Cazals-Hatem, D.(5);Billiauws, L.(1);Bouhnik, Y.(1);Joly, F.(1);Uzzan, M.(1);
(1)Hôpital Beaujon AP-HP-, Gastro-entérologie, Paris, France;(2)Hôpital Necker APHP, Génétique, Paris, France;(3)Hôpital Necker APHP, Gastro-entérologie, Paris, France;(4)INSERM Paris, Immunologie, Paris, France;(5)Hôpital Beaujon AP-HP-, Anatomopathologie, Paris, France
P673: Microbial diversity in newly diagnosed treatment naïve Inflammatory Bowel Disease patientsECCO'21 VirtualYear: 2021
Authors: Ellul , S.(1);Rausch , P.(2);Pisani , A.(3);Bang , C.(2);ellul , P.(3);Franke , A.(2);
(1)Division of Paediatric Surgery- Department of Surgery- Mater Dei Hospital- Malta-, Paediatric Surgery, Paola, Malta;(2)Institute of Clinical Molecular Biology- Christian-Albrechts-University of Kiel- Kiel- Germany, Institute of Clinical Molecular Biology- Christian-Albrechts-University of Kiel- Kiel- Germany, Kiel, Germany;(3)Division of Gastroenterology- Department of Medicine- Mater Dei Hospital- Malta, Division of Gastroenterology- Department of Medicine- Mater Dei Hospital- Malta, Swatar, Malta
P674: Definition of a microbial signature as a predictor of anti-TNFα treatment responseECCO'21 VirtualYear: 2021
Authors: Oliver, L.(1);Busquets, D.(2);Amoedo, J.(1);Ramió-Pujol, S.(1);Malagón, M.(1);Serrano, M.(1);Bahí, A.(3);Lluansí, A.(3);Gilabert, P.(4);Miquel-Cusachs, J.O.(2);Sàbat, M.(5);Guardiola, J.(4);Serra-Pagès, M.(1);Garcia-Gil, J.(6);Aldeguer, X.(2);
(1)GoodGut, Laboratory, Girona, Spain;(2)Hospital Universitari Doctor Josep Trueta, Gastroenterology, Girona, Spain;(3)Institut d'Investigació Biomèdica de Girona IdIBGi, Research, Salt, Spain;(4)Hospital Universitari de Bellvitge, Gastroenterology, Hospitalet de Llobregat, Spain;(5)Hospital de Santa Caterina, Gastroenterology, Salt, Spain;(6)Universitat de Girona, Biology, Girona, Spain
P675: Flavonoid-degrading bacteria have central positions in correlation network analysis in patients with Inflammatory Bowel DiseaseECCO'21 VirtualYear: 2021
Authors: Pisani, A.(1);Rausch, P.(2);Ellul, S.(3);Bang, C.(2);Tabone, T.(1);Marantidis Cordina, C.(4);Zahra, G.(5);Ellul, P.(1);Franke, A.(2);
(1)Mater Dei Hospital, Department of Gastroenterology, Msida, Malta;(2)Christian-Albrechts-University of Kiel, Institute of Clinical Molecular Biology, Kiel, Germany;(3)Mater Dei Hospital, Division of Paediatric Surgery- Department of Surgery, Msida, Malta;(4)Mater Dei Hospital, Department of Microbiology, Msida, Malta;(5)Mater Dei Hospital, Molecular Diagnostics- Department of Pathology, Msida, Malta
P676: The small intestinal microbiome in Crohn’s disease is characterised by increased luminal diversity and stable mucosa-associated communitiesECCO'21 VirtualYear: 2021
Authors: Wauters, L.(1,2);Tito, R.(3,4);Ceulemans, M.(2);Moens, A.(1,2);Outtier, A.(1);Sabino, J.(1,2);Ferrante, M.(1,2);Vermeire, S.(1,2);Vanuytsel, T.(1,2);Raes, J.(4,5);
(1)University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium;(2)KU Leuven, Translational Research in Gastrointestinal Disorders, Leuven, Belgium;(3)KU Leuven, Department of Microbiology and Immunology, Leuven, Belgium;(4)VIB, Center for Microbiology, Leuven, Belgium;(5)KU Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium
P677: Fungal abundance is related to inflammatory status in Ulcerative ColitisECCO'21 VirtualYear: 2021
Authors: Herrera De Guise, C.M.(1); Sarrabayrouse, G.(2);Varela, E.(2);Robles, V.(1);Borruel, N.(1);Mayorga, L.F.(1);Casellas, F.(1);Ibarz, A.(2);Perez, Z.(1);Robles, M.(1);Guarner, F.(1);
(1)Hospital Universitari Vall d'Hebron, Gastroenterology, Barcelona, Spain;(2)Hospital Universitari Vall d'Hebron, Vall d’Hebron Research Institute, Barcelona, Spain
P678: Definition of a microbial signature as a predictor of post-surgical recurrence in patients with Crohn's diseaseECCO'21 VirtualYear: 2021
Authors: Oliver, L.(1);Amoedo, J.(1);Julià, D.(2);Camps, B.(3);Ramió-Pujol, S.(1);Malagón, M.(1);Torres, P.(4);Domènech, E.(4);Guardiola, J.(3);Serra-Pagès, M.(1);Garcia-Gil, J.(5);Aldeguer, X.(2);
(1)GoodGut, Laboratory, Girona, Spain;(2)Hospital Universitari Doctor Josep Trueta, General and digestive surgery, Girona, Spain;(3)Hospital Universitari de Bellvitge, Gastroenterology, Hospitalet de Llobregat, Spain;(4)Hospital Germans Trias i Pujol, Gastroenterology, Badalona, Spain;(5)Universitat de Girona, Biology, Girona, Spain
P679: The keystone bacterium Christensenella minuta improves colitis in in vivo preclinical Inflammatory Bowel Disease modelsECCO'21 VirtualYear: 2021
Authors: Kropp, C.(1);Le Corf, K.(2);Relizani, K.(2);Tambosco, K.(1);Martinez, C.(2);Chain, F.(1);Rawadi, G.(2);Langella, P.(1);Claus, S.(2);Martin, R.(1);
(1)INRAE, Micalis, Jouy-en-Josas, France;(2)Ysopia Bioscience, Ysopia Bioscience, Bordeaux, France
P680: Similar gut bacterial composition between patients with ulcerative colitis and healthy controls in a high prevalence population: a cross-sectional study of the Faroe Islands IBD cohortECCO'21 VirtualYear: 2021
Authors: Á Fríðriksmørk BerbisáCand.Scient, M.(1);Rubek Nielsen, K.(2);Midjord, J.(2);Oddmarsdóttir Gregersen , N.(3);Ingham, A.C.(4);Burisch, J.(5);Gratton Vang, A.(1);
(1)Fróðskaparsetur Føroya, Department of Health Science, Tórshavn, Faroe Islands;(2)National Hospital of the Faroe Islands, Department of Medicine, Tórshavn, Faroe Islands;(3)Genetic Biobank of the Faroe Islands, FarGen, Tórshavn, Faroe Islands;(4)Statens Serum Institut, Dept. of Bacteria- Parasites and Fungi, Copenhagen, Denmark;(5)North Zealand University Hospital, Department of Gastroenterology, Fredrikssund, Denmark
P681: Higher in vitro mucin degradation, but no increased paracellular permeability by faecal water from Crohn’s disease patientsECCO'21 VirtualYear: 2021
Authors: Becker, H.(1);Kameli, N.(2);Rustichelli, A.(1);Britt, H.(1);Stassen, F.(2);Penders, J.(2);Jonkers, D.(1);
(1)Maastricht University Medical Center+, Internal Medicine, Maastricht, The Netherlands;(2)Maastricht University Medical Center+, Medical Microbiology, Maastricht, The Netherlands
P682: Antibiotic resistome profiles of fecal Escherichia coli isolates in association with Crohn’s diseaseECCO'21 VirtualYear: 2021
Authors: Siniagina, M.(1);Markelova, M.(1);Boulygina, E.(1);Laikov, A.(1);Khusnutdinova, D.(1);Abdulkhakov, S.(1);Grigoryeva, T.(1);
(1)Kazan Federal University, Institute of fundamental medicine and biology, Kazan, Russian Federation
P683: Patients with newly diagnosed fistulizing perianal Crohn's disease have a distinct microbial signatureECCO'21 VirtualYear: 2021
Authors: Goren, I.(1);Ian, W.(2);Reshef, L.(3);Sharar Fischler, T.(1);Pauker, M.(1);Silverman, J.(4);Dotan, I.(1);Yanai, H.(1);
(1)Rabin Medical Center, Division of Gastroenterology, Petah Tikva, Israel;(2)Rabin Medical Center, Colorectal surgery- Department of surgery, Petah Tikva, Israel;(3)Tel Aviv University, Molecular microbiology and biotechnology, Tel Aviv, Israel;(4)Tel Aviv University, Sackler Faculty of Medicine, Tel Aviv, Israel
P685: Gut microbiota in patients with Inflammatory Bowel Disease during remissionECCO'21 VirtualYear: 2021
Authors: Pisani, A.(1);Rausch, P.(2);Ellul, S.(3);Bang, C.(2);Tabone, T.(1);Marantidis Cordina, C.(4);Zahra, G.(5);Ellul, P.(1);Franke, A.(2);
(1)Mater Dei Hospital, Department of Gastroenterology, Msida, Malta;(2)Christian-Albrechts-University of Kiel, Institute of Clinical Molecular Biology, Kiel, Germany;(3)Mater Dei Hospital, Division of Paediatric Surgery- Department of Surgery, Msida, Malta;(4)Mater Dei Hospital, Department of Microbiology, Msida, Malta;(5)Mater Dei Hospital, Molecular Diagnostics- Department of Pathology, Msida, Malta
P686: Novel grape-derived prebiotic selectively enhances abundance and metabolic activity of IBD and IBS faecal butyrate producing bacteria in an in vitro model of intestinal fermentationECCO'21 VirtualYear: 2021
Authors: Oliver, L.(1);Ramió-Pujol, S.(1);Amoedo, J.(1);Malagón, M.(1);Serrano, M.(1);Bahí, A.(2);Lluansí, A.(2);Busquets, D.(3);Pardo, L.(3);Serra-Pagès, M.(1);Aldeguer, X.(3);Garcia-Gil, J.(4);
(1)GoodGut, Laboratory, Girona, Spain;(2)Institut d'Investigació Biomèdica de Girona IdIBGi, Resarch, Salt, Spain;(3)Hospital Universitari Doctor Josep Trueta, Gastroenterology, Girona, Spain;(4)Universitat de Girona, Biology, Girona, Spain
P687: Development of a panel of microbial markers to distinguish transient from pathological dysbiosisECCO'21 VirtualYear: 2021
Authors: Oliver, L.(1);Ramió-Pujol, S.(1);Malagón, M.(1);Serrano, M.(1);Bahí, A.(2);Busquets, D.(3);Torrealba, L.(3);Serra-Pagès, M.(1);Aldeguer, X.(3);Garcia-Gil, J.(4);
(1)GoodGut, Laboratory, Girona, Spain;(2)Institut d'Investigació Biomèdica de Girona IdIBGi, Research, Salt, Spain;(3)Hospital Universitari Doctor Josep Trueta, Gastroenterology, Girona, Spain;(4)Universitat de Girona, Biology, Girona, Spain
P688: Association of Akkermansia muciniphila with a healthy gut microbiomeECCO'21 VirtualYear: 2021
Authors: Ellul, S.(1);Rausch , P.(2);PIsani, A.(3);Bang, C.(4);Ellul, P.(3);Franke, A.(4);
(1)Division of Paediatric Surgery- Department of Surgery- Mater Dei Hospital- Malta-, Paediatric Surgery, Paola, Malta;(2)Institute of Clinical Molecular Biology- Christian-Albrechts-University of Kiel- Kiel- Germany, Institute of Clinical Molecular Biology- Christian-Albrechts-University of Kiel- Kiel- GermanyKiel, Keil, Germany;(3)Division of Gastroenterology- Department of Medicine- Mater Dei Hospital- Malta, Division of Gastroenterology- Department of Medicine- Mater Dei Hospital- Malta, Msida, Malta;(4)Institute of Clinical Molecular Biology- Christian-Albrechts-University of Kiel- Kiel- Germany, Institute of Clinical Molecular Biology- Christian-Albrechts-University of Kiel- Kiel- Germany, Kiel, Germany
P689: Aeromonas infection and Inflammatory Bowel Disease: a single tertiary center analysisECCO'21 VirtualYear: 2021
Authors: Alves Da Silva, J.(1);Pereira Guedes, T.(1);Falcão, D.(1);Neves, S.(2);Costa, P.(3);Lago, P.(1);Pedroto, I.(1);Salgado, M.(1);
(1)Centro Hospitalar e Universitário do Porto, Gastroenterology, Porto, Portugal;(2)Centro Hospitalar e Universitário do Porto, Infectious Disease, Porto, Portugal;(3)Centro Hospitalar e Universitário do Porto, Microbiology, Porto, Portugal
