¹IBD Unit, Gastroenterology and Hepatology Department, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain, ²Rheumatology Department, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain, ³Clinical Pharmacology Department, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain

¹Center for Digestive Diseases and Liver Transplantation, Fundeni Clinical Institute, Gastroenterology, Bucharest, Romania, ²Center for Digestive Diseases and Liver Transplantation, Fundeni Clinical Institute, Bucharest, Romania

¹Tel Aviv Sourasky Medical Center, Pediatric Gastroenterology, Tel Aviv, Israel, ²Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

¹OLVG Lab BV, Laboratory of Hematology and Clinical Chemistry, Amsterdam, The Netherlands, ²OLVG Oost, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands

¹Centro Hospitalar de Vila Nova de Gaia e Espinho, Vila Nova de Gaia, Portugal

¹IRCCS Sacro Cuore Don Calabria, IBD Unit, Negrar, Italy, ²IRCCS Sacro Cuore Don Calabria, General Surgery, Negrar, Italy, ³IRCCS Sacro Cuore Don Calabria, Division of Medical Oncology, Negrar, Italy, ⁴IRCCS Sacro Cuore Don Calabria, Gastroenterology, Negrar, Italy

¹Clinic for Gastroenterology and Hepatology, Belgrade, Serbia

¹Hospital La Fe, Valencia, Spain, ²Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBEREHD), Valencia, Spain, ³Hospital Gregorio Marañón, Department of Gastroenterology, Madrid, Spain, ⁴Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain, ⁵Hospital General Universitario de Castellón, Castellón, Spain, ⁶Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ⁷Hospital Universitario Virgen Macarena, Sevilla, Spain, ⁸Takeda Farmacéutica España SA, Madrid, Spain, ⁹Hospital Universitario Río Hortega, Department of Gastroenterology, Valladolid, Spain, ¹⁰University Clinic Hospital of Valencia, IBD Unit, Gastroenterology Department, Valencia, Spain, ¹¹Hospital Clínico Universitario de Santiago, Department of Gastroenterology, Santiago de Compostela, Spain, ¹²Hospital Universitario Cruces, Department of Gastroenterology, Bilbao, Spain, ¹³Hospital Dr. Josep Trueta, Department of Gastroenterology, Girona, Spain, ¹⁴Hospital de Sagunto, IBD Unit, Gastroenterology Section, Sagunto, Spain, ¹⁵University of Cardenal Herrera-CEU, Castellón, Spain, ¹⁶Hospital Universitario de Burgos, Burgos, Spain, ¹⁷Hospital Ramón y Cajal, Department of Gastroenterology, Madrid, Spain

¹Fondazione Policlinico A. Gemelli IRCCS, Internal Medicine and Gastroenterology, Rome, Italy, ²State Hospital, Gastroenterology and Endoscopy Unit, Borgo Maggiore, San Marino, ³Fondazione Policlinico A. Gemelli IRCCS, Instiute of Pathology, Rome, Italy, ⁴Infermi Hospital, Institute of Pathology, Rimini, Italy, ⁵Fondazione Policlinico A. Gemelli IRCCS, Presidio Columbus, Rome, Italy

¹Gastroenterology and Endoscopy Unit, ARNAS Civico-Di Cristina-Benfratelli Hospital, Palermo, Italy

¹Tzaneion General Hospital of Piraeus, Gastroenterology, Piraeus, Greece

¹University Hospital CHU of Liège, Liege, Belgium, ²Saint-Pierre University Hospital,, Brussels, Belgium, ³Imeldaziekenhuis, Bonheiden, Belgium, ⁴Hospital CHC, Liège, Belgium, ⁵CHwapi Notre Dame, Tournai, Belgium, ⁶Maria Middelares Medical Centre, Ghent, Belgium, ⁷UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium, ⁸Ziekenhuis Oost Limburg, Genk, Belgium, ⁹Onze-Lieve-Vrouwziekenhuis, Aalst, Belgium, ¹⁰University Hospitals Leuven, Leuven, Belgium, ¹¹AZ Groeninge Hospital, Kortrijk, Belgium, ¹²AZ St Lucas, Gent, Belgium, ¹³Hopital Universitaire Erasme, Brussels, Belgium, ¹⁴Clinique St-Pierre, Ottignies, Belgium, ¹⁵CHU UCL Namur site Sainte Elisabeth, Brussels, Belgium, ¹⁶AZ Delta, Roeselare, Belgium, ¹⁷Hospital CHR de la Citadelle, Liège, Belgium, ¹⁸Jessa Ziekenhuis, Hasselt, Belgium, ¹⁹CHU Ambroise-Paré, Mons, Belgium, ²⁰Takeda Pharmaceuticals, Medical Affairs, Brussels, Belgium, ²¹Takeda Pharmaceuticals Company, Statistics, Boston, USA, ²²Takeda Pharmaceuticals, Epidemiology, London, UK

¹Amsterdam UMC, Gastroenterology and Hepatology, Amsterdam, The Netherlands, ²MUMC+, Gastroenterology and Hepatology, Maastricht, The Netherlands, ³University of Warwick, School of Engineering, Coventry, UK, ⁴Spaarne Gasthuis, Gastroenterology and Hepatology, Hoofddorp, The Netherlands, ⁵OLVG West, Gastroenterology and Hepatology, Amsterdam, The Netherlands, ⁶Amsterdam UMC, Pediatric gastroenterology, Amsterdam, The Netherlands

¹Kyungpook National University, School of Medicine, Internal Medicine, Daegu, South Korea, ²Keimyung University, School of Medicine, Internal Medicine, Daegu, South Korea, ³Catholic University of Daegu, School of Medicine, Internal Medicine, Daegu, South Korea, ⁴Yeungnam University College of Medicine, Internal Medicine, Daegu, South Korea, ⁵Dongguk University School of Medicine, Internal Medicine, Gyeongju, South Korea

¹Universitá della Campania, Colorectal Surgery, Department of Medical, Surgical, Neurological, Metabolic and Ageing Sciences, Naples, Italy, ²Università della Campania Luigi Vanvitelli, Section of Statistic, Department of Mental Health and Public Medicine, Naples, Italy, ³Royal Marsden Hospital and Imperial College London, Unit of Colorectal Surgery, Royal Marsden Hospital, London, UK

¹Queen Silvia′s Children Hospital, Gothenburg, Sweden, ²Institute of Clinical Sciences, The Sahlgrenska Academy at University of Gothenburg, Department of pediatrics, Gothenburg, Sweden, ³Premier Research LLC, Durham/NC, USA, ⁴Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Gothenburg, Sweden, ⁵Clinical and Molecular Osteoporosis Research Unit, Department of Clinical Sciences and Orthopedics, University of Lund, Malmö, Sweden, ⁶Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Geriatric Medicine, Department of Internal Medicine and Clinical Nutrition, Gothenburg, Sweden, ⁷Sahlgrenska University Hospital, Geriatric Medicine, Gothenburg, Sweden

¹Université de Lorraine, Vandœuvre-lès-Nancy (Nancy University Hospital, Lorraine University), Nancy, France, ²University of Western Ontario, London, Canada, ³Mayo Clinic, Phoenix, USA, ⁴Genentech, South San Francisco, USA, ⁵Roche, Burgess Hill, UK, ⁶University of Chicago Medicine, Chicago, USA

¹Clinical Hospital Centre Zagreb, Department of Gastroenterology and Hepatology, Zagreb, Croatia, ²Nordic Bioscience A/S, Biomarkers and Research, Herlev, Denmark, ³Unit of Clinical Nutrition, University Hospital Zagreb, Zagreb, Croatia, ⁴University of Zagreb, School of Medicine, Zagreb, Croatia

¹Erasmus MC, Department of Gastroenterology and Hepatology, Rotterdam, The Netherlands, ²Erasmus MC, Department of Public Health, Rotterdam, The Netherlands, ³Leiden UMC, Department of Clinical Biostatistics and Medical Decision Making, Leiden, The Netherlands, ⁴Madrid Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP) and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Department of Gastroenterology, Madrid, Spain, ⁵Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Department of Gastroenterology and Hepatology, Sheffield, UK, ⁶Western General Hospital, Department of Gastroenterology and Hepatology, Edinburgh, UK, ⁷University of Szeged, Department of Medicine, Szeged, Hungary, ⁸Centre Hospitalier Universitaire de Liège, Department of Gastroenterology and Hepatology, Liège, Belgium, ⁹INSERM U717, Department of Biostatistics and Clinical Epidemiology, Paris, France, ¹⁰IBD Clinical and Research Centre, Iscare a.s, Prague, Czech Republic, ¹¹Institute of Medical Biochemistry and Laboratory Diagnostics, 1st Medical Faculty and General Teaching Hospital, Prague, Czech Republic, ¹²Amsterdam UMC, Academic Medical Centre, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands

¹Graduate School of Medicine, Kyoto University, Department of Gastroenterology and Hepatology, Kyoto, Japan