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P020: Regulation of intestinal epithelial homeostasis by the IBD risk gene CCNY

ECCO '19 Copenhagen

Year: 2019
Authors:

S. Heil1, A. Molinas1, S. Koch*1

1Linköping University, Clinical and Experimental Medicine, Linköping, Sweden

P022: Galectin-3, galectin-9, and galectin-3 binding protein in patients with inflammatory bowel diseases

ECCO '19 Copenhagen

Year: 2019
Authors:

D. Cibor*1, K. Szczeklik2, D. Owczarek1, T. Mach1

1Jagiellonian University Medical College, Gastroenterology, Hepatology and Infectious Diseases, Cracow, Poland, 2Jagiellonian University Medical College, Integrated Dentistry, Cracow, Poland

P023: A resting state fMRI study in patients with active Crohn’s disease

ECCO '19 Copenhagen

Year: 2019
Authors:

G. Thapaliya1, S. Eldeghaidy2, S. J. Radford1, S. Francis2, G. Moran*1

1The University of Nottingham, NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and School of Medicine, Nottingham, UK, 2The University of Nottingham, Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, Nottingham, UK

P024: Plasma acetic acid, propanoic acid, and isobutyric acid are associated with treatment response in pouchitis patients treated with antibiotics

ECCO '19 Copenhagen

Year: 2019
Authors:

J. Segal*1, M. Sarafian2, J. I. Serrano Contreras2, A. Pechlivanis2, Y. Siaw3, S. Clark1,2, L. Braz1,2, E. Holmes2, A. Hart1,2

1St Marks Hospital, Gastroenterology, Harrow, UK, 2Imperial College London, London, UK, 3Hillingdon Hospital, Gastroenterology, Hillingdon, UK

P025: Comparison of abdominal lymph nodes between healthy volunteers and patients with Crohn’s disease

ECCO '19 Copenhagen

Year: 2019
Authors:

H. Williams1, C. Hoad1, R. Scott2, G. Aithal2, L. Marciani2, G. Moran*2, P. Gowland1

1University of Nottingham, Sir Peter Mansfield Imaging Centre, Nottingham, UK, 2University of Nottingham, Nottingham Digestive Diseases Biomedical Research Centre, Nottingham, UK

P026: Establishment of an in vitro system to evaluate the therapeutic effect of the investigational drug on ulcerative colitis using human colonic organoids

ECCO '19 Copenhagen

Year: 2019
Authors:

S. Hibiya*1, K. Tsuchiya1, R. Nishimura1, T. Shirasaki1, S. Watanabe1, N. Katsukura1, T. Nakamura2, M. Watanabe1

1Tokyo Medical and Dental University, Gastroenterology and Hepatology, Tokyo, Japan, 2Tokyo Medical and Dental University, Advanced Therapeutics for Gastrointestinal Diseases, Tokyo, Japan

P027: Machine learning approaches to identify prognosis indicators from microbiome data

ECCO '19 Copenhagen

Year: 2019
Authors:

M. Madgwick*1,2, P. Sudhakar1,2,3, T. Korcsmáros1,2

1Earlham Institute, Norwich, UK, 2Quadram Institute, Norwich, UK, 3KU Leuven Department of Chronic Diseases, Leuven, Belgium

P028: Telomere shortening and genetic anticipation in IBD

ECCO '19 Copenhagen

Year: 2019
Authors:

B. Truta*1, S. Brant1, M. Armani1, L. Datta1, T. Bayless1

1Johns Hopkins University, Baltimore, USA

P029: Serum bile acids profiling in IBD patients treated with anti-TNFs

ECCO '19 Copenhagen

Year: 2019
Authors:

G. Roda*1, E. Porru2, K. Katsanos3, A. Skamnelos3, K. Kyriakidi3, D. K. Christodoulou3, C. Caliceti2, G. Fiorino1, S. Danese1, A. Roda2

1Humanitas Research Hospital, IBD Centre, Milan, Italy, 2Department of Chemistry ‘Giacomo Ciamician’, Alma Mater Studiorum, Bologna, Italy, 3Department of Gastroenterology, University Hospital of Ioannina, Ioannina, Greece

P030: Myeloid calcineurin in the control of immune checkpoint inhibition in intestinal tumour development

ECCO '19 Copenhagen

Year: 2019
Authors:

K. Peuker*1, A. Strigli1, L. Južnić1, L. Matthiesen1, M. Koch1, S. Krüger2, D. Tauriello3, E. Batlle3, C. Röcken2, J. Hampe1,4, S. Zeissig1,4

1TU Dresden, Center for Regenerative Therapies, Dresden, Germany, 2University Medical Center Schleswig-Holstein, Institute of Pathology, Kiel, Germany, 3The Barcelona Institute of Science and Technology, Institute for Research in Biomedicine, Barcelona, Spain, 4University Hospital Carl-Gustav Carus, Department of Internal Medicine I, Dresden, Germany

P031: Impact of nutritional antigens in inflammatory bowel disease patients

ECCO '19 Copenhagen

Year: 2019
Authors:

Y. Rodríguez Sillke*1, M. Schumann1, D. Lissner1, F. Branchi1, R. Glauben1, B. Siegmund1

1Charité Universitätsmedizin Berlin, Medical Department (Gastroenterology, Infectious Diseases, Rheumatology), Berlin, Germany

P032: Hepatocyte growth factor and MET in ulcerative colitis, novel drug targets impairing neutrophil recruitment?

ECCO '19 Copenhagen

Year: 2019
Authors:

B. Verstockt*1,2, M. Stakenborg2, W-J. Wollants2, G. Van Assche1,2, M. Ferrante1,2, S. Vermeire1,2, G. Matteoli2

1University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, 2KU Leuven, Department of Chronic Diseases, Metabolism and Ageing, Translational Research Center for Gastrointestinal Disorders (TARGID), Leuven, Belgium

P033: Periostin regulates ER-stress mediated intestinal subepithelial myofibroblasts function to promote fibrosis in Crohn’s disease

ECCO '19 Copenhagen

Year: 2019
Authors:

C. Li*1, J. Kuemmerle1

1Virginia Commonwealth University, Internal Medicine, Richmond, USA

P034: A dietary fibre intervention shapes the microbiome towards an anti-inflammatory tone

ECCO '19 Copenhagen

Year: 2019
Authors:

S. J. Reider*1,2, S. Moosmang3, J. Tragust1, L. Trgovec-Greif4, S. Tragust5, N. Przysiecki1, S. Sturm3, H. Tilg2, T. Rattei4, H. Stuppner3, A. R. Moschen1,2

1Medical University Innsbruck, Christian Doppler Laboratory for Mucosal Immunology, Innsbruck, Austria, 2Medical University Innsbruck, Department for Internal Medicine I – Gastroenterology, Hepatology, Endocrinology and Metabolism, Innsbruck, Austria, 3University of Innsbruck, Institute of Pharmacy / Pharmacognosy and Center for Molecular Biosciences Innsbruck (CMBI), Innsbruck, Austria, 4University of Vienna, Division of Computational Systems Biology, Department of Microbiology and Ecosystem Science, Vienna, Austria, 5University Halle, Institute of Biology – General Zoology, Halle (Saale), Germany

P035: Pharmacological inhibition of the canonical WNT signalling pathway represents a potential novel therapy for fibrosis in Crohn’s disease

ECCO '19 Copenhagen

Year: 2019
Authors:

A. Lewis*1, A. Nijhuis1, G. Berti1, C. L. Bishop2, R. Feakins3, J. O. Lindsay4, A. Silver1

1Blizard Institute, Barts and The London School of Medicine and Dentistry, Centre for Genomics and Child Health, London, UK, 2Blizard Institute, Barts and The London School of Medicine and Dentistry, Centre for Cell Biology and Cutaneous Research, London, UK, 3Department of Histopathology, The Royal London Hospital, London, UK, 4Blizard Institute, Barts and The London School of Medicine and Dentistry, Centre for Immunobiology, London, UK

P036: Expression of CD69 on peripheral lymphocytes predicts treatment response in Acute Severe ulcerative colitis

ECCO '19 Copenhagen

Year: 2019
Authors:

M. C. Choy*1,2,3, J. Yu2, M. Congiu2, P. Pelpola2, J. Nigro2, R. Burder1, K. Boyd1, M. McGuckin4, A. J. Corbett5, L. Kjer-Nielsen5, J. McCluskey5, K. Visvanathan2, P. De Cruz1,3

1Austin Health, Gastroenterology, Heidelberg, Australia, 2St Vincent's Hospital, Immunology Research Centre, Fitzroy, Australia, 3Austin Academic Centre, University of Melbourne, Medicine, Heidelberg, Australia, 4University of Melbourne, Department of Medicine, Dentistry and Health Sciences, Parkville, Australia, 5The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Department of Microbiology and Immunology, Parkville, Australia

P037: USP16-mediated deubiquitination of calcineurin A controls peripheral T cells maintenance and attenuates intestinal inflammation

ECCO '19 Copenhagen

Year: 2019
Authors:

Y. Zhang*1,2, R. Liu1,2, K. Fan3, L. Huang1,2, Z. Gao3, T. Huang3, J. Zhong3, X. Mao3, X. Mao3, F. Wang3, P. Xiao1,2, Y. Zhao1,2, Y. Li3, X. Feng3, J. Jin3, Q. Cao1,2

1Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Gastroenterology, Hangzhou, China, 2Inflammatory Bowel Disease Center of Sir Run Run Shaw Hospital, Hangzhou, China, 3MOE Laboratory of Biosystem Homeostasis and Protection, and Life Sciences Institute, Zhejiang University, Hangzhou, China

P038: Expression analysis in colitis-associated carcinoma: a role for osteopontin?

ECCO '19 Copenhagen

Year: 2019
Authors:

D. Cardoso da Silva*1, M. Sehn2, S. Elezkurtaj3, A. Kühl4, B. Siegmund1, M. Kreis2, C. Holmer2, M. Hummel3, J. Gröne5, M. Schumann1

1Charité Universitätsmedizin Berlin, Department for Gastroenterology, Infectiology and Rheumatology, Berlin, Germany, 2Charité Universitätsmedizin Berlin, Department for General and Visceral Surgery, Berlin, Germany, 3Charité Universitätsmedizin Berlin, Department for Pathology, Berlin, Germany, 4Charité Universitätsmedizin Berlin, Department for Immunopathology, Berlin, Germany, 5Rotes Kreuz Krankenhaus, Department for General and Visceral Surgery, Bremen, Germany

P039: Tracking intestinal epithelial cells with fluorescent dyes

ECCO '19 Copenhagen

Year: 2019
Authors:

J. Seidelin*1, F. H. Bergenheim1, O. H. Nielsen1

1Herlev Hospital, University of Copenhagen, Department of Gastroenterology, Herlev, Denmark