¹Medical University of Vienna, Vienna, Austria, ²University of California San Diego, La Jolla, CA, USA, ³Humanitas University, Milan, Italy, ⁴University of Nice Sophia Antipolis, Hospital l'Archet, Nice, France, ⁵Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland, ⁶Clinic of Gastroenterology and Hepatology, Military Medical Academy, Belgrade, Serbia, ⁷Charles University Hospital, Hradec Králové, Czech Republic, ⁸Gastroenterology Center, Nitra, Slovakia, ⁹Nature Coast Clinical Research, Inverness, FL, USA, ¹⁰Seoul National University College of Medicine, Seoul, South Korea, ¹¹Alfred Hospital, Melbourne, VIC, Australia, ¹²Zymo Consulting Group, Newtown Square, PA, USA, ¹³Shire, Zug, Switzerland, ¹⁴Shire, Lexington, MA, USA, ¹⁵Cytel Inc., Cambridge, MA, USA, ¹⁶University Hospitals Leuven, Leuven, Belgium

¹University California San Diego, La Jolla, California, USA, ²Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, New York, NY, USA, ³Kitasato University, Center for Advanced IBD Research and Treatment, Tokyo, Japan, ⁴Eli Lilly and Company, Lilly Biotechnology Center, San Diego, CA, USA, ⁵Eli Lilly and Company, Indianapolis, IN, USA, ⁶UZ Leuven, KU Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium

¹University of California San Diego, Medicine, San Diego, USA, ²Theravance Biopharma US, Inc., South San Francisco, USA, ³Janssen R&D, Springhouse, USA, ⁴Hospital Clinic Barcelona, Gastroenterology, Barcelona, Spain

¹Humanitas Research Hospital, Milan, Italy, ²Icahn School of Medicine at Mount Sinai, New York, USA, ³Janssen Research & Development, LLC, Spring House, USA, ⁴Janssen Scientific Affairs, LLC, Horsham, USA, ⁵Concord Hospital, Sydney, Australia, ⁶Macquarie University Hospital, Sydney, Australia, ⁷Auckland City Hospital, Auckland, New Zealand, ⁸University of Auckland, Auckland, New Zealand, ⁹Cedars-Sinai Medical Center, Los Angeles, USA, ¹⁰University of Leuven, Leuven, Belgium

¹Kiel University, Institute of Clinical Molecular Biology, Kiel, Germany, ²Yonsei University College of Medicine, Department of Internal Medicine and Institute of Gastroenterology, Seoul, South Korea, ³National Institute of Food and Drug Safety Evaluation, Clinical Research Division, Cheongju, South Korea

¹Academic Medical Center, Gastroenterology and Hepatology, Amsterdam, The Netherlands, ²Amsterdam UMC, location AMC, Gastroenterology and Hepatology, Amsterdam, The Netherlands, ³Amsterdam UMC, Location AMC, Hospital Pharmacy, Amsterdam, The Netherlands, ⁴Projections Research Inc., Phoenixville, USA, ⁵Tergooi Hospital, Blaricum, The Netherlands, ⁶Onze Lieve Vrouwe Gasthuis, Gastroenterology and Hepatology, Amsterdam, The Netherlands, ⁷Amsterdam UMC, location AMC, Clinical Genetics, Amsterdam, The Netherlands, ⁸Amsterdam UMC, location VuMc, Gastroenterology and Hepatology, Amsterdam, The Netherlands

¹University Teaching Hospital Lueneburg, Department of Internal Medicine and Gastroenterology, Lueneburg, Germany, ²Gastroenterology Practice, Oldenburg, Germany, ³Biostatistik Tuebingen, Tuebingen, Germany, ⁴AbbVie Deutschland GmbH & Co.KG, Medical Department Gastroenterology, Wiesbaden, Germany

¹University of Alberta, Paediatrics, Edmonton, Canada, ²Hospital for Sick Children, University of Toronto, Paediatrics, Toronto, Canada, ³The Children's Hospital University of Manitoba, Paediatrics, Winnipeg, Canada, ⁴Stollery Children's Hospital University of Alberta, Paediatrics, Edmonton, Canada, ⁵Alberta Health Services, Biochemistry, Edmonton, Canada, ⁶Alberta Health Services, Paediatrics, Edmonton, Canada, ⁷Alberta Children's Hospital University of Calgary, Paediatrics and Community Health Sciences, Calgary, Canada, ⁸Projections Research, Phoenixville, USA

¹Hospital Santa Maria, Centro Hospitalar Lisboa Norte, Gastrenterology and Hepatology Unit, Lisbon, Portugal

¹King's College London, London, UK, ²BRC Bioinformatics core, London, UK, ³King's College Hospital, London, UK

¹St Mark's Hospital and Academic Institute, Surgical Epidemiology Trials and Outcome Centre, London, UK, ²Imperial College London, Department of Surgery and Cancer, London, UK, ³Statsconsultancy Ltd., Buckinghamshire, UK, ⁴St Mark's Hospital and Academic Institute, London, UK, ⁵Imperial College London, Dr Foster Unit, Department of Primary Care and Public Health, London, UK

¹Medical University Vienna, Vienna, Austria, ²Yeungnam University Hospital, Daegu, South Korea, ³Clinical Hospital Center Osijek, Osijek, Croatia, ⁴Sheba Medical Center, Gastroenterology, Tel Hashomer, Israel, ⁵Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁶Pauls Stradins Clinical University Hospital, Rīga, Latvia, ⁷Novosibirsk State Medical University, Novosibirsk, Russian Federation, ⁸Private Small_Scale Enterprise Medical Centre ‘Pulse’, Vinnytsya, Ukraine, ⁹University Hospital Schleswig-Holstein, Kiel, Germany, ¹⁰Sheba Medical Center, Tel Hashomer, Israel, ¹¹Celltrion, Inc., Incheon, South Korea, ¹²Asan Medical Center, Seoul, South Korea

¹Montpellier University Hospital, Gastroenterology, Montpellier, France, ²Lille University Hospital, Gastroenterology, Lille, France, ³Saint-Antoine University Hospital, Gastroenterology, Paris, France, ⁴Besançon University Hospital, Gastroenterology, Besançon, France, ⁵Beaujon University Hospital, Gastroenterology, Clichy, France, ⁶Lyon University Hospital, Gastroenterology, Lyon, France, ⁷Tours University Hospital, Gastroenterology, Tours, France, ⁸Marseille University Hospital, Gastroenterology, Marseille, France, ⁹Nancy University Hospital, Gastroenterology, Vandoeuvre-les-Nancy, France, ¹⁰Nice University Hospital, Gastroenterology, Nice, France, ¹¹Caen University Hospital, Gastroenterology, Caen, France, ¹²Cochin University Hospital, Gastroenterology, Paris, France, ¹³Valenciennes General Hospital, Gastroenterology, Valenciennes, France, ¹⁴Nantes University Hospital, Gastroenterology, Nantes, France, ¹⁵Toulouse University Hospital, Gastroenterology, Toulouse, France, ¹⁶Clermont-Ferrand University Hospital, Gastroenterology, Clermont-Ferrand, France, ¹⁷Saint-Etienne University Hospital, Gastroenterology, Saint-Etienne, France, ¹⁸Beaujon University Hospital, Radiology, Clichy, France, ¹⁹Saint-Louis University Hospital, Biostatistics, Paris, France

¹Queen Mary Hospital, Medicine, Hong Kong, Hong Kong, ²The University of Hong Kong, Medicine, Hong Kong, Hong Kong

¹Asan Medical Center, Gastroenterology, Seoul, South Korea, ²Asan Medical Center, Radiology, Seoul, South Korea, ³Asan Medical Center, Inflammatory Bowel Disease Center, Seoul, South Korea, ⁴Asan Medical Center, Clinical Epidemiology and Biostatistics, Seoul, South Korea

¹McMaster University, Division of Gastroenterology, Department of Medicine, Farncombe Family Digestive Health Research Institute, Hamilton, Canada, ²University of Toronto, Division of Gastroenterology, Mount Sinai Hospital, Toronto, Canada, ³Ministry of Health and Long-Term Care, Health Analytics Branch, Toronto, Canada

¹University Hospital of Erlangen, Department of Medicine 1, Division of Gastroenterology, Erlangen, Germany, ²University Hospital of Erlangen, Institute of Pathology, Erlangen, Germany, ³University of Birmingham, Institute of Translational Medicine, Birmingham, UK

¹Canberra Hospital, Gastroenterology and Hepatology Unit, Canberra, Australia, ²ACT Pathology, Canberra Hospital, Canberra, Australia, ³Health Analytics Research Centre, Canberra Hospital, Canberra, Australia, ⁴ANU Medical School, Australian National University, Canberra, Australia

¹Hyogo College of Medicine, Intestinal Inflammation Research, Nishinomiya, Japan, ²Nishishita GI Hospital, Osaka, Japan, ³Saga University, Saga, Japan, ⁴Hiroshima University, Hiroshima, Jamaica, ⁵Prefectural University of Hiroshima, Hiroshima, Japan, ⁶Osakafu Saiseikai Nakatsu Hospital, Osaka, Japan, ⁷Kyoto Katsura Hospital, Kyoto, Japan, ⁸Fukuoka University Chikushi Hospital, Fukuoka, Japan, ⁹Osaka Medical College, Osaka, Japan, ¹⁰Kinki University, Osaka, Japan, ¹¹Toho University Sakura Medical Center, Chiba, Japan, ¹²Fujita Medical University, Aichi, Japan, ¹³The Jikei University School of Medicine, Tokyo, Japan, ¹⁴The Cancer Institute Hospital of JFCR, Tokyo, Japan, ¹⁵National Cancer Center Hospital, Tokyo, Japan, ¹⁶Hiroshima University, Hiroshima, Japan, ¹⁷Niigata University, Niigata, Japan

¹University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, ²KU Leuven, Department of Chronic Diseases, Metabolism and Ageing, Translational Research Center for Gastrointestinal Disorders (TARGID), Leuven, Belgium, ³Earlham Institute, Norwich, UK, ⁴Quadram Institute, Norwich, Belgium, ⁵KU Leuven, Department of Microbiology and Immunology, Laboratory of Clinical Immunology, Leuven, Belgium, ⁶KU Leuven, Department of Human genetics, Laboratory for Complex Genetics, Leuven, Belgium