OP11: Longitudinal profiling of mucosal immune cell composition using multiplex immunohistochemistry identifies drug- and response-specific patterns in Ulcerative ColitisECCO'21 VirtualYear: 2021
Authors: Volk, V.(1);Aden, K.(2);Tran, F.(2);Mishra, N.(3);Bernardes, J.(3);Röcken, C.(4);Schreiber, S.(2);Feuerhake, F.(1);Rosenstiel, P.(3)
(1)Hannover Medical School, Institute for Pathology, Hannover, Germany;(2)Kiel University and University Medical Center Schleswig-Holstein- Campus Kiel, Institute of Clinical Molecular Biology and Department of Internal Medicine I, Kiel, Germany;(3)Kiel University and University Medical Center Schleswig-Holstein- Campus Kiel, Institute of Clinical Molecular Biology, Kiel, Germany;(4)Kiel University and University Medical Center Schleswig-Holstein- Campus Kiel, Department of Pathology, Kiel, Germany
OP12: Blood proteins related to immunoregulation or cellular junctions reveal distinct biological profiles associated with the risk of short-term versus mid/long-term relapse in Crohn’s Disease patients stopping infliximabECCO'21 VirtualYear: 2021
Authors: Pierre , N.(1);Huynh-Thu , V.A.(2);Allez , M.(3);Bouhnik , Y.(4);Laharie , D.(5);Bourreille , A.(6);Colombel , J.F.(7);Meuwis , M.A.(1);Louis , E.(1)
(1)GIGA-R- University of Liège, Laboratory of Translational Gastroenterology, Liège, Belgium;(2)University of Liege, Department of Electrical Engineering and Computer Science, Liège, Belgium;(3)Université de Paris, Service d’Hépato-Gastroentérologie- Hôpital Saint Louis- APHP, Paris, France;(4)Hôpital Beaujon, Service de Gastroentérologie et Assistance Nutritive, Clichy, France;(5)Centre Hospitalier Universitaire de Bordeaux, Service d’Hépato-Gastroentérologie, Bordeaux, France;(6)Centre Hospitalier Universitaire de Nantes, Institut des maladies de l’appareil digestif, Nantes, France;(7)Icahn School of Medicine at Mount Sina, Division of Gastroenterology, New York, United States GETAID (Groupe d’Etude Thérapeutique des Affections Inflammatoires du tube Digestif)
OP13: Mucosal organoids capture Innate Lymphoid Cells (ILC) tissue-specific development and reveal that Inflammatory Bowel Disease-associated ILC modulate intestinal remodellingECCO'21 VirtualYear: 2021
Authors: Jowett, G.M.(1);Read, E.(1);Norman, M.D.(2);Arevalo, P.A.(1);Vilà González, M.(3);Roberts, L.(4);Vallier, L.(3);Curtis, M.(1);Lord, G.(5);Gentleman, E.(2);Neves, J.F.(1)
(1)King's College London, Centre for Host Microbiome Interactions, London, United Kingdom;(2)King's College London, Centre for Craniofacial & Regenerative Biology, London, United Kingdom;(3)Cambridge University, Cambridge Stem Cell Institute, Cambridge, United Kingdom;(4)King's College London, School of Immunology and Microbiology Sciences, London, United Kingdom;(5)Manchester University, Faculty of Biology- Medicine and Health, Manchester, United Kingdom
OP14: Extracellular RNAs as liquid biopsy non-invasive biomarker in IBDECCO'21 VirtualYear: 2021
Authors: Verstockt., B.(1,2);Verstockt, S.(2);Sabino, J.(1,2);Ferrante, M.(1,2);Vermeire, S.(1,2)
(1)University Hospitals Leuven, Dpt. Gastroenterology and Hepatology, Leuven, Belgium;(2)KU Leuven, Dpt. Chronic Diseases- Metabolism and Ageing- TARGID-IBD, Leuven, Belgium
OP15: Cyclic exclusive enteral nutrition to maintain longterm drug-free remission in Paediatric Crohn’s Disease: The CD HOPE study of the GETAID pédiatriqueECCO'21 VirtualYear: 2021
Authors: Pigneur Arnaud, B.(1);Martinez-Vinson, C.(2);Bourmaud, A.(3);Swellen, G.(4);Duclaux-Loras, R.(5);Hugot, J.P.(2);Roman, C.(6);Dumant, C.(7);Spyckerelle, C.(8);Guinard Samuel, V.(9);Willot, S.(10);Dupont, C.(11);Breton, A.(12);Caron, N.(13);Chaillou, E.(14);Rebouissoux, L.(15);Triolo, V.(16);Bertrand, V.(17);Pages, J.(3);Djamal-Dine, D.(18);Bonneton, M.(19);Uhlen, S.(20);Catteau, N.(21);Coopman, S.(22);Viala, J.(2);Ruemmele, F.M.(1)
(1)Hospital Necker Enfants Malades, Department of Paediatric Gastroenterology, Paris, France;(2)Robert Debre Hospital Paris, Pediatric Gastroenterology, Paris, France;(3)Robert Debre Hospital Paris, Clinical Epidemiology, Paris, France;(4)CHU Rennes, Pediatric Gastroenterology, Rennes, France;(5)CHU Lyon, Pediatric Gastroenterology, Lyon, France;(6)APHM, Pediatric Gastroenterology, Marseille, France;(7)CHU Rouen, Pediatric Gastroenterology, Rouen, France;(8)Université Cathologique Lille, Pediatric Gastroenterology, Lille, France;(9)Hopital Trousseau, Pediatric Gastroenterology, Paris, France;(10)CHU Tours, Pediatric Gastroenterology, Tours, France;(11)CHU Caen, Pediatric Gastroenterology, Caen, France;(12)CHU Toulouse, Pediatric Gastroenterology, Toulouse, France;(13)CHU Clermont Ferrand, Pediatric Gastroenterology, Clermont Ferrand, France;(14)CHU Angers, Pediatric Gastroenterology, Angers, France;(15)CHU Bordeaux, Pediatric Gastroenterology, Bordeaux, France;(16)CHU Lenval, Pediatric Gastroenterology, Nice, France;(17)CH Le Havre, Pediatric Gastroenterology, Le Havre, France;(18)CHU Amiens, Pediatric Gastroenterology, Amiens, France;(19)CHRU Nancy, Pediatric Gastroenterology, Nancy, France;(20)CH Valenciennes, Pediatric Gastroenterology, Valenciennes, France;(21)CHU Nimes, Pediatric Gastroenterology, Nimes, France;(22)CHRU Lille, Pediatric Gastroenterology, Lille, France
OP16: Characterization of the Clinical Features and Outcomes of Paediatric Patients with Isolated Colonic Crohn’s Disease: A Multi-center Study from the Porto Group of ESPGHANECCO'21 VirtualYear: 2021
Authors: Berger, T.(1);Miin Lee, H.(2);Ramasamy Padmanaban, L.(2);Wine, E.(3);Yerushalmi, A.(4);Hojsak, I.(5);Bronski, J.(6);Serban, D.(7);Yogev, D.(8);Ledder, O.(8);Lionetti, P.(9);Scarrallo, L.(9);Gasparetto, M.(10);Croft, N.(10);Miele, E.(11);Staiano, A.(11);Meredith, J.(12);Aloi, M.(13);Alvisi, P.(14);Urlep, D.(15);Weiss, B.(1);Knudsen, M.(16);Matar, M.(17);Manuel Navas-López, V.(18);Romano, C.(19);Dipasquale, V.(19);Norsa, L.(20);Kolho, K.L.(21);Shamir, R.(17);Shouval, D.(17)
(1)Edmond and Lily Safra Children's Hospital, Pediatric Gastroenterology, Ramat Gan, Israel;(2)King's College Hospital NHS Foundation Trust, Paediatric Liver- GI & Nutrition Centre and Mowat Labs, London, United Kingdom;(3)University of Alberta, Edmonton Pediatric IBD Clinic, Edmonton, Canada;(4)Dana-Dwek Children's Hospital- Tel Aviv Sourasky Medical Center, Pediatric Gastroenterology Unit, Tel Aviv, Israel;(5)Children's Hospital Zagreb, Pediatric Gastroenterology, Zagreb, Croatia;(6)University Hospital Motol, Department of Paediatrics, Prauge, Czech Republic;(7)'Iuliu Hatieganu' University of Medicine and Pharmacy, 2nd Department of Paediatrics, Cluj-Napoca, Romania;(8)Shaare Zedek Medical Center, Juliet Keidan Institute of Paediatric Gastroenterology and Nutrition, Jerusalem, Israel;(9)University of Florence, Department Neurofarba, Florence, Italy;(10)Barts and the London School of Medicine, Pediatric Gastroenterology, London, United Kingdom;(11)University of Naples 'Federico II', Department of Translational Medical Science- Section of Pediatrics, Naples, Italy;(12)Royal Hospital for Sick Children, Department of Paediatric Gastroenterology and Nutrition, Edinburgh, United Kingdom;(13)Sapienza University of Rome, Pediatric Gastroenterology and Liver Unit, Rome, Italy;(14)Maggiore Hospital, Pediatric Unit, Bologna, Italy;(15)Children's Hospital University Medical Centre Ljubljana, Department of Gastroenterology Hepatology and Nutrition, Ljubljana, Slovenia;(16)Copenhagen University Hospital, The pediatric Department, Hvidovre, Denmark;(17)Schneider Children's Medical Center of Israel, Institute of Gastroenterology- Nutrition and Liver Diseases, Petah Tiqwa, Israel;(18)Hospital Regional Universitario de Málaga, Pediatric Gastroenterology and Nutrition Unit, Malaga, Spain;(19)University of Messina, Pediatric Gastroenterology and Cystic Fibrosis Unit- Department of Human Pathology in Adulthood and Childhood “G. Barresi”, Messina, Italy;(20)Papa Giovanni XXIII Hospital, Paediatric Hepatology Gastroenterology and Transplantation, Bergamo, Italy;(21)University of Helsinki, Paediatric Gastroenterology of the Children's Hospital, Helsinki, Finland
OP17: Impact of phenotypic and genetic factors on Crohn’s Disease evolution in a cohort of 13,926 patientsECCO'21 VirtualYear: 2021
Authors: Zhang, Q.(1);Fachal, L.(1);Shawky, R.(2);Parkes, M.(2,3,4);Anderson, C.(1);Raine, T.(1,4)
(1)Wellcome Trust Sanger Institute, Human Genetics, Cambridge, United Kingdom;(2)Cambridge University Hospitals NHS Foundation Trust, IBD BioResource- NIHR BioResource, Cambridge, United Kingdom;(3)University of Cambridge, Division of Gastroenterology and Hepatology- Department of Medicine, Cambridge, United Kingdom;(4)Cambridge University Hospitals NHS Foundation Trust, Department of Gastroenterology, Cambridge, United Kingdom
OP18: Treatment of perianal fistulas in Crohn’s Disease: Surgical closure after anti-TNF induction treatment versus anti-TNF without surgery (PISA II) - A patient preference RCTECCO'21 VirtualYear: 2021
Authors: Meima - van Praag, E.(1);van Rijn, K.(2);Snijder, A.(3);Wasmann, K.(4);Stoker, J.(2);D'Haens, G.(3);Gecse, K.(3);Gerhards, M.(5);Jansen, J.(6);Pronk, A.(7);van Tyl, S.(8);Zimmerman, D.(9);Bruin, K.(10);Spinelli, A.(11);Danese, S.(12);van der Bilt, J.(13);Mundt, M.(14);Bemelman, W.(1);Buskens, C.(1)
(1)Amsterdam UMC, Surgery, Amsterdam, The Netherlands;(2)Amsterdam UMC, Radiology and Nuclear Medicine, Amsterdam, The Netherlands;(3)Amsterdam UMC, Gastroenterology and Hepatology, Amsterdam, The Netherlands;(4)Amsterdam UMC, Surgery, Amsterda-, The Netherlands;(5)OLVG, Surgery, Amsterdam, The Netherlands;(6)OLVG, Gastroenterology and Hepatology, Amsterdam, The Netherlands;(7)Diakonessenhuis, Surgery, Utrecht, The Netherlands;(8)Diakonessenhuis, Gastroenterology and Hepatology, Utrecht, The Netherlands;(9)Elisabeth-TweeSteden Hospital, Surgery, Tilburg, The Netherlands;(10)Elisabeth-TweeSteden Hospital, Gastroenterology and Hepatology, Tilburg, The Netherlands;(11)Humanitas Research Hospital and Humanitas University, Surgery, Milan, Italy;(12)Humanitas Research Hospital and Humanitas University, Gastroenterology, Milan, Italy;(13)Flevoziekenhuis, Surgery, Almere, The Netherlands;(14)Flevoziekenhuis, Gastroenterology and Hepatology, Almere, The Netherlands
OP19: Disease course and treatment outcomes of early resected Crohn's Disease patients: A Danish nationwide cohort study from 1997 to 2015ECCO'21 VirtualYear: 2021
Authors: Sarikaya, M.(1);Zhao, M.(2);Bendtsen, F.(1,2);Burisch, J.(2)
(1)University of Copenhagen- Copenhagen- Denmark, Faculty of Health Sciences, Copenhagen, Denmark;(2)Hvidovre University Hospital- Kettegaard Alle 30, The Gastro Unit- Medical Division, Hvidovre, Denmark
OP20: Risk and predictors of surgery in a newly diagnosed cohort of IBD patients in the biologic era: Results from the EpidemIBD studyECCO'21 VirtualYear: 2021
Authors: Chaparro, M.(1);Garre, A.(1);Núñez Ortiz , A.(2);Diz-Lois Palomares, M.T.(3);Rodríguez, C.(4);Riestra, S.(5);Vela, M.(6); Benítez, J.M.(7);Fernández Salgado, E.(8);Sánchez Rodríguez, E.(9);Hernández, V.(10);Ferreiro-Iglesias, R.(11);Ponferrada Díaz, Á.(12);Barrio, J.(13); Huguet, J.M.(14);Arias, L.(15);Martín-Arranz, M.D.(16);Calvet, X.(17);Ginard, D.(18);Alonso-Abreu, I.(19);Fernández-Salazar, L.(20);Varela Trastoy, P.(21);Rivero, M.(22);Vera-Mendoza, I.(23);Vega, P.(24);Navarro, P.(25);Sierra, M.(26); Cabriada, J.L.(27);Aguas, M.(28);Vicente, R.(29);Navarro-Llavat, M.(30);Echarri, A.(31);Gomollón, F.(32);Guerra del Río, E.(33);Casanova, M.J.(1);Spicakova, K.(34);Ortiz de Zarate, J.(35);Alonso-Galán, H.(36);Barreiro-de Acosta, M.(11);Gisbert, J.P.(1)
(1)Hospital Universitario de La Princesa- Instituto de Investigación Sanitaria Princesa IIS-IP- Universidad Autónoma de Madrid- and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBERehd, Gastroenterology Unit, Madrid, Spain;(2)Hospital Universitario Virgen del Rocío, Gastroenterology Unit, Sevilla, Spain;(3)Hospital Universitario A Coruña, Gastroenterology Unit, A Coruña, Spain;(4)Complejo Hospitalario de Navarra, Gastroenterology Unit, Pamplona, Spain;(5)Hospital Universitario Central de Asturias and ISPA, Gastroenterology Unit, Oviedo, Spain;(6)Complejo Hospitalario Universitario Ntra. Sra. de Candelaria, Gastroenterology Unit, Santa Cruz de Tenerife, Spain;(7)Hospital Universitario Reina Sofía and IMIBIC, Gastroenterology Unit, Córdoba, Spain;(8)Complexo Hospitalario Universitario de Pontevedra- Instituto de Investigación Sanitaria Galicia Sur, Gastroenterology Unit, Pontevedra, Spain;(9)Hospital Ramón y Cajal, Gastroenterology Unit, Madrid, Spain;(10)Hospital Álvaro Cunqueiro. Estrutura Organizativa de Xestión Integrada de Vigo, Gastroenterology Unit, Vigo, Spain;(11)Complexo Hospitalario Universitario de Santiago, Gastroenterology Unit, Santiago de Compostela, Spain;(12)Hospital Universitario Infanta Leonor, Gastroenterology Unit, Madrid, Spain;(13)Hospital Universitario Rio Hortega, Gastroenterology Unit, Valladolid, Spain;(14)Consorcio Hospital General Universitario de Valencia, Gastroenterology Unit, Valencia, Spain;(15)Hospital Universitario de Burgos, Gastroenterology Unit, Burgos, Spain;(16)Hospital Universitario La Paz- School of Medicine. Universidad Autónoma de Madrid. Hospital La Paz Institute for Health Research- La Paz Hospital, Gastroenterology Unit, Madrid, Spain;(17)Hospital Universitari Parc Taulí- Sabadell. Departament de Medicina- Universitat Autònoma de Barcelona. CIBERehd - Instituto de Salud Carlos III, Gastroenterology Unit, Barcelona, Spain;(18)Hospital Universitari Son Espases, Gastroenterology Unit, Palma de Mallorca, Spain;(19)Hospital Universitario de Canarias H.U.C, Gastroenterology Unit, Santa Cruz de Tenerife, Spain;(20)Hospital Clínico Universitario de Valladolid, Gastroenterology Unit, Valladolid, Spain;(21)Hospital de Cabueñes, Gastroenterology Unit, Gijón, Spain;(22)Hospital Universitario Marqués de Valdecilla and IDIVAL, Gastroenterology Unit, Santander, Spain;(23)Hospital Universitario Puerta de Hierro Majadahonda, Gastroenterology Unit, Madrid, Spain;(24)Complexo Hospitalario Universitario de Ourense, Gastroenterology Unit, Ourense, Spain;(25)Hospital Clínico Universitario de Valencia- Universitat de València, Gastroenterology Unit, Valencia, Spain;(26)Complejo Asistencial Universitario de León, Gastroenterology Unit, León, Spain;(27)Hospital de Galdakao-Usansolo, Gastroenterology Unit, Galdakao, Spain;(28)Hospital Universitari i Politecnic La Fe and CIBERehd, Gastroenterology Unit, Valencia, Spain;(29)Hospital Universitario Miguel Servet, Gastroenterology Unit, Zaragoza, Spain;(30)Hospital de Sant Joan Despí Moisès Broggi, Gastroenterology Unit, Barcelona, Spain;(31)Complejo Hospitalario Universitario de Ferrol, Gastroenterology Unit, A Coruña, Spain;(32)Hospital Clínico Universitario “Lozano Blesa”- IIS Aragón and CIBERehd, Gastroenterology Unit, Zaragoza, Spain;(33)Hospital Universitario de Gran Canaria Dr. Negrín, Gastroenterology Unit, Las Palmas, Spain;(34)Hospital Universitario de Araba sede Txagorritxu y sede Santiago, Gastroenterology Unit, Álava, Spain;(35)Hospital Universitario de Basurto, Gastroenterology Unit, Bilbao, Spain;(36)Hospital Universitario Donostia-Donostia Unibertsitate Ospitalea- Guipuzkoa and Organizacion Sanitaria Integrada Tolosaldea- Clínica Santa María de la Asunción, Gastroenterology Unit, Guipúzcoa, Spain On behalf of EpidemIBD Study Group
OP21: Predictive value of Milan Ultrasound Criteria in Ulcerative Colitis: A prospective observational cohort studyECCO'21 VirtualYear: 2021
Authors: Allocca, M.(1);Dell’Avalle, C.(2);Furfaro, F.(2);Craviotto, V.(2);Zilli, A.(2);D'Amico, F.(2);Peyrin-Biroulet, L.(3);Fiorino, G.(1);Danese, S.(1)
(1)Humanitas University- Pieve Emanuele, Department of Biomedical Sciences, Milan, Italy;(2)Humanitas Clinical and Research Center – IRCCS Rozzano, IBD Unit, Milan, Italy;(3)University Hospital of Nancy- Université de Lorraine, Department of Gastroenterology, Nancy, Italy
OP22: Factors independently associated with fatigue in IBD: Results from the baseline dataset of the PREdiCCt studyECCO'21 VirtualYear: 2021
Authors: Derikx, L.(1,2);Siakavellas, S.(2);Derr, L.(2);Williams, L.(2);Nikolas, P.(2);Jenkinson, P.(2);Lucaciu, L.(2);Constantine-Cooke, N.(3);Covil, K.(2);Murdoch, L.(2);Jones, G.R.(2,4);Lees, C.(2,5)
(1)Radboud University Nijmegen Medical Centre, Inflammatory Bowel Disease Centre- Department of Gastroenterology and Hepatology- Route 455, Nijmegen, The Netherlands;(2)Western General Hospital, The Edinburgh IBD Unit, Edinburgh, United Kingdom;(3)University of Edinburgh- Western General Hospital, MRC Human Genetics Unit- Institute of Genetics and Molecular Medicine, Edinburgh, United Kingdom;(4)University of Edinburgh, Centre for Inflammation Research- The Queen's Medical Research Institute, Edinburgh, United Kingdom;(5)University of Edinburgh- Western General Hospital, Centre for Genomics and Experimental Medicine- Institute of Genetics and Molecular Medicine, Edinburgh, United Kingdom PREdiCCt Study Writing Group
OP23: Efficacy and safety of upadacitinib as induction therapy in patients with Moderately to Severely Active Ulcerative Colitis: Results from phase 3 U-ACCOMPLISH studyECCO'21 VirtualYear: 2021
Authors: Vermeire, S.(1);Danese, S.(2);Zhou, W.(3);Pangan, A.(3);Greenbloom, S.(4);D'Haens, G.(5);Panes, J.(6);Juillerat, P.(7);Lindsay, J.O.(8);Loftus Jr, E.V.(9);Sandborn, W.J.(10);Reinisch, W.(11);Sanchez Gonzalez, Y.(3);Huang, B.(3);Xie, W.(3);Liu, J.(3);Weinreich, M.A.(3);Panaccione, R.(12)
(1)KU Leuven, Gastroenterology, Leuven, Belgium;(2)Instituto Clinico Humanitas, Gastroenterology, Milan, Italy;(3)AbbVie Inc., Research & Development, North Chicago- Illinois, United States;(4)Toronto Digestive Disease Associates, Clinical Research, Ontario, Canada;(5)Amsterdam UMC campus AMC, Gastroenterology, Amsterdam, Netherlands Antilles;(6)Hospital Clínic Barcelona- IDIBAPS- CIBERehd, Inflammatory Bowel Diseases Unit, Barcelona, Spain;(7)Bern University Hospital- Clinic for Visceral Surgery and Medicine, Gastroenterology, Bern, Switzerland;(8)Barts and the London School of Medicine and Dentistry- Queen Mary University of London, Centre for Immunobiology, London, United Kingdom;(9)Mayo Clinic, Division of Gastroenterology and Hepatology, Rochester- Minnesota, United States;(10)University of California San Diego, Division of Gastroenterology, La Jolla- California, United States;(11)Medical University of Vienna, Gastroenterology, Vienna, Austria;(12)University of Calgary, Division of Gastroenterology, Calgary- Alberta, Canada
OP24: Efficacy and safety of upadacitinib induction therapy in patients with Moderately to Severely Active Ulcerative Colitis: Results from the phase 3 U-ACHIEVE studyECCO'21 VirtualYear: 2021
Authors: Danese, S.(1);Vermeire , S.(2);Zhou, W.(3);Pangan, A.(4);Siffledeen, J.(5);Hébuterne, X.(6);Nakase, H.(7);Higgins, P.(8);Chen, M.H.(9);Sanchez-Gonzalez, Y.(3);Huang, B.(3);Xie, W.(4);Liu, J.(4);Weinreich, M.(4);Pannaccione, R.(10)
(1)IRCCS Humanitas Research Hospital, Department of Gastroenterology, Rozzano, Italy;(2)2University Hospital Leuven, Department of Gastroenterology & Hepatology, Leuven, Belgium;(3)AbbVie Inc, na, North Chicago, United States;(4)AbbVie Inc., na, North Chicago, United States;(5)University of Alberta, na, Edmonton, Canada;(6)Université Côte d’Azur, na, Nice, France;(7)Sapporo Medical University School of Medicine, Department of Gastroenterology and Hepatology, Sapporo, Japan;(8)University of Michigan, Department of Medicine- Division of Gastroenterology, Ann Arbor, United States;(9)The First Affiliated Hospital of Sun Yat-sen University, Division of Gastroenterology, Guangzhou, China;(10)University of Calgary, Division of Gastroenterology, Calgary, Canada
OP25: Efficacy of filgotinib in patients with Ulcerative Colitis by line of therapy in the phase 2b/3 SELECTION trialECCO'21 VirtualYear: 2021
Authors: Peyrin-Biroulet, L.(1);Dotan, I.(2,3);Hibi, T.(4);Taliadouros, V.(5);Oortwijn, A.(5);Zhao, S.(6);Zhang, J.(6);Hsieh, J.(6);Feagan, B.(7,8)
(1)Nancy University Hospital, Inflammatory Bowel Disease Unit, Nancy, France;(2)Rabin Medical Center Beilinson Hospital, Division of Gastroenterology, Petah Tikva, Israel;(3)Tel Aviv University, Sackler Faculty of Medicine, Tel Aviv, Israel;(4)Kitasato Institute Hospital Kitasato University, Center for Advanced IBD Research and Treatment, Tokyo, Japan;(5)Galapagos, Nv, Leiden, The Netherlands;(6)Gilead Sciences, Inc., Foster City CA, United States;(7)Alimentiv Inc., London, Ontario, Canada;(8)Western University, London, Ontario, Canada
OP26: Risankizumab induces early clinical remission and response in patients with Moderate-to-Severe Crohn’s Disease: Results from the phase 3 ADVANCE and MOTIVATE studiesECCO'21 VirtualYear: 2021
Authors: Schreiber , S.W.(1);Ferrante , M.(2);Panaccione , R.(3);Colombel , J.F.(4);Hisamatsu , T.(5);Lim , A.(6);Lindsay , J.O.(7);Rubin , D.T.(8);Sandborn , W.J.(9);Neimark , E.(10);Song , A.P.(10);Liao , X.(10);Feng , T.(10);Berg , S.(10);Wallace , K.(10);D’Haens , G.R.(11)
(1)University Hospital Schleswig-Holstein, Kiel, Germany;(2)University Hospitals Leuven, University Hospitals Leuven, Leuven, Belgium;(3)University of Calgary, Calgary, Canada;(4)Icahn School of Medicine at Mount Sinai, New York, United States;(5)Kyorin University School of Medicine, Mitaka, Japan;(6)John Flynn Private Hospital, Tugun, Australia;(7)Barts and the London School of Medicine and Queen Mary University of London, London, United Kingdom;(8)The University of Chicago Medicine Inflammatory Bowel Disease Center, Chicago, United States;(9)University of California San Diego, La Jolla, United States;(10)AbbVie Inc, North Chicago, United States;(11)Amsterdam University Medical Center, Amsterdam, The Netherlands
OP28: The effect of guselkumab induction therapy on early clinical outcome measures in patients with Moderately to Severely Active Crohn’s Disease: Results from the phase 2 GALAXI 1 studyECCO'21 VirtualYear: 2021
Authors: Danese, S.(1);Sandborn, W.J.(2);Feagan, B.G.(3);Weisel, K.(4);Gonzalez, S.(4);Frustaci, M.E.(4);Yang, Z.(4);Johanns, J.(4);Germinaro, M.(4);Afzali, A.(5);Andrews, J.M.(6);D’Haens, G.(7);Hisamatsu, T.(8);Panaccione, R.(9);Reinisch, W.(10);Rubin, D.T.(11);Sands, B.E.(12);Panes, J.(13)
(1)Humanitas Research Hospital, Inflammatory Bowel Diseases Center, Milan, Italy;(2)University of California San Diego, Health Sciences- Gastroenterology, La Jolla- California, United States;(3)Robarts Clinical Trials-Western University, Gastroenterology, London- Ontario, Canada;(4)Janssen Research & Development- LLC, Immunology, Spring House- Pennsylvania, United States;(5)Ohio State University Wexner Medical Center, Gastroenterology, Columbus Ohio, United States;(6)Royal Adelaide Hospital & University of Adelaide, Dept of Gastroenterology and Hepatology, Adelaide- South Australia, Australia;(7)Amsterdam UMC, Gastroenterology, Amsterdam, The Netherlands;(8)Kyorin University, Gastroenterology and Hepatology, Tokyo, Japan;(9)University of Calgary, Gastroenterology & Hepatology, Calgary- Alberta, Canada;(10)Medical University of Vienna, Division of Gastroenterology and Hepatology, Vienna, Austria;(11)University of Chicago Medicine Inflammatory Bowel Disease Center, Gastroenterology, Chicago- Illinois, United States;(12)Icahn School of Medicine at Mount Sinai, Gastroenterology, New York- New York, United States;(13)Hospital Clínic de Barcelona- IDIBAPS- CIBERehd, Gastroenterology, Barcelona, Spain GALAXI 1 Investigators
OP29: Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiomeECCO'21 VirtualYear: 2021
Authors: Bolte, L.(1,2);Vich Vila, A.(1,2);Imhann, F.(1,2);Collij, V.(1,2);Peters, V.(1);Fu, J.(2,3);Kurilshikov, A.(2);Campmans-Kuijpers, M.(1);Dijkstra, G.(1);Wijmenga, C.(2);Zhernakova, A.(2);Weersma, R.(1)
(1)University Groningen and University Medical Center Groningen, Dept. of Gastroenterology & Hepatology, Groningen, The Netherlands;(2)University Groningen and University Medical Center Groningen, Dept. of Genetics, Groningen, The Netherlands;(3)University Groningen and University Medical Center Groningen, Dept. of Paediatrics, Groningen, The Netherlands
OP30: Lyophilised orally administered faecal microbiota transplantation for Active Ulcerative Colitis (LOTUS study)ECCO'21 VirtualYear: 2021
Authors: Haifer, C.(1);Saikal, A.(2);Paramsothy, S.(1);Borody, T.J.(3);Ghaly, S.(2);Kaakoush, N.O.(4);Leong, R.(1)
(1)The University of Sydney, Concord Clinical School, Sydney, Australia;(2)St Vincent's Hospital Sydney, Department of Gastroenterology and Hepatology, Sydney, Australia;(3)Centre for Digestive Diseases, Centre for Digestive Diseases, Sydney, Australia;(4)The University of New South Wales, Faculty of Medicine, Sydney, Australia