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P483 Vedolizumab serum drug levels are not associated with clinical outcomes or markers of disease activity in inflammatory bowel disease

ECCO'20 Vienna

Year: 2020
Authors:

S. Shields1, J.P. Seenan1, E. Nowell1, A. Dunlop2, P. Galloway2, J. Macdonald1

1Gastroenterology, Queen Elizabeth University Hospital, Glasgow, UK, 2Biochemistry, Queen Elizabeth University Hospital, Glasgow, UK

P484 Effectiveness and safety of ustekinumab in patients with Crohn’s disease: a real-world experience

ECCO'20 Vienna

Year: 2020
Authors:

D. Mohammad1, A. Alshahrani1,2, Y. Bao1, R. Alramdan1, A. Rajani1, U. Chauhan1, B. Salena1, F. Tse1, E. Greenwald1, S. Albashir1, S. Halder1, D. Armstrong1, J. Marshall1, N. Narula1

1Gastroenterology, McMaster University Medical Centre and Farncombe Family Digestive Health Diseases Research Institute, Hamilton, Canada, 2Gastroenterology, Najran University, Najran, Saudi Arabia

P485 Switching infliximab biosimilar: No adverse impact on inflammatory bowel disease control or drug levels with the first or second switch

ECCO'20 Vienna

Year: 2020
Authors:

R. Luber1, R. O’Neill2, S. Singh2, Z. Arkir3, P. Irving1

1Department of Gastroenterology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK, 2Department of Pharmacy, Guy’s and St Thomas’ NHS Foundation Trust, London, UK, 3Guy’s and St Thomas’ NHS Foundation Trust, Viapath, London, UK

P486 Assessing the efficacy of biologics in ucerative colitis: a real-life, observational retrospective multicentre study with propensity score analysis (AURORA): Focus on patients naive to biologics

ECCO'20 Vienna

Year: 2020
Authors:

A. Cassinotti1, N. Mezzina1, D. Di Paolo2, M.V. Lenti3, C. Bezzio4, D. Stradella5, M. Mauri6, V. Zadro1, C. Cortellezzi7, C. Ricci8, V. Casini9, E. Radice10, A. Massari1, S. Ardizzone1, L. Pastorelli2, A. Di Sabatino3, G. Manes4, F. Caprioli11, M. Vecchi11, R. Tari5, P. Occhipinti5, M. Fichera6, P. Invernizzi6, M. Parravicini7, S. Segato7, F. Pace9, P.A. Testoni10, C. Tinelli12, A. De Silvestri12

1Department of Gastroenterology, Luigi Sacco University Hospital, Milan, Italy, 2Gastroenterology and Digestive Endoscopy Unit, IRCCS Policlinico San Donato, San Donato Milanese - Milano, Italy, 3First Department of Medicine, Istituto di Ricovero e Cura a Carattere Scientifico San Matteo Hospital Foundation - University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico San Matteo Hospital Foundation - University of Pavia, Pavia, Italy, 4Department of Gastroenterology, ASST Rhodense - Rho and Garbagnate Milanese Hospital, Milano, Italy, 5Department of Gastroenterology, ‘Maggiore Della Carità’ Hospital - Novara, Novara, Italy, 6Gastroenterology Division, San Gerardo Hospital- ASST Monza, Monza, Italy, 7ASST Sette Laghi- Ospedale di Circolo Fondazione Macchi, Division of Gastroenterology, Varese, Italy, 8Spedali Civili and University of Brescia, Gastroenterology Section - 1st Medical Clinic, Brescia, Italy, 9Gastroenterology, ASST Bergamo EST-Ospedale Bolognini, Bergamo, Italy, 10Gastroenterology Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy, 11Department of Gastroenterology and Endoscopy, IRCCS Ca’ Granda Foundation - University of Milan, Milano, Italy, 12Fondazione IRCCS Policlinico San Matteo, Servizio di Epidemiologia Clinica e Biometria Direzione Scientifica, Pavia, Italy

P487 Development and validation of a new patient-reported outcome measure for Crohn’s perianal fistula: Crohn’s anal fistula quality-of-life (CAF-QoL) scale

ECCO'20 Vienna

Year: 2020
Authors:

S. Adegbola1, L. Dibley2, K. Sahnan1, P. Tozer1, T. Wade3, A. Verjee4, R. Sawyer4, S. Mannick4, D. McCluskey4, N. Yassin1, R. Phillips1, C. Norton3, A. Hart1

1Department of Colorectal Surgery, St. Mark’s Hospital, Harrow, UK, 2Faculty of Health and Education, University of Greenwich, London, UK, 3King’s College London, Florence Nightingale Faculty of Nursing, London, UK, 4Patient and Public Involvement Team, Patient and Public Involvement Team, London, UK

P488 How reliable is the online medical information on paediatric inflammatory bowel diseases?

ECCO'20 Vienna

Year: 2020
Authors:

M. Velasco Rodríguez-Belvís1, L.M. Palomino Pérez1, C. Sánchez Fernández-Bravo1, A. Sanchiz Perea2, L.F. Jose Luis1, G. Domínguez Ortega1, E. Cañedo Villarroya1, C.C. Pedrón Giner1, M.P. Jorge1, S. Rodríguez Manchón1, A. Muñoz González1, R.A. Muñoz Codoceo1

1Department of Gastroenterology and Nutrition, Hospital Infantil Universitario Niño Jesús, Madrid, Spain, 2Department of Pediatrics, Hospital Infantil Universitario Niño Jesús, Madrid, Spain

P489 Are patients with inflammatory bowel disease receiving an adequate immunisation?

ECCO'20 Vienna

Year: 2020
Authors:

D. Simian1, P. Núñez2, L. Flores1, C. Figueroa1, P. Ibáñez1, U. Kronberg1, J. Lubascher1, G. Pizarro1, R. Quera1

1Clínica Las Condes, Gastroenterology Department - Inflammatory Bowel Disease, Santiago, Chile, 2Gastroenterology Department - IBD Fellow Clínica Las Condes, San Juan de Dios Hospital, Santiago, Chile

P490 Assessment of body weight changes in patients with inflammatory bowel diseases initiating biologic therapy: A prospective cohort study

ECCO'20 Vienna

Year: 2020
Authors:

N. Borren, W. Tan, A. Jess, P.H.M. Li, J. Garber, J. Luther, F. Colizzo, H. Khalili, A. Ananthakrishnan

Division of Gastroenterology, Massachusetts General Hospital, Boston, USA

P491 De-escalation of dose-intensified anti-TNF therapy in IBD patients in sustained deep remission

ECCO'20 Vienna

Year: 2020
Authors:

I. Chu1,2, R. Little1,2, M. Sparrow1,2, M. Ward1,2

1Gastroenterology, Alfred Hospital- Alfred Health, Melbourne, Australia, 2Faculty of Medicine Nursing and Health Sciences, Monash University, Melbourne, Australia

P492 Use of bowel ultrasound to assess disease activity in Crohn’s disease patients after induction therapy with infliximab

ECCO'20 Vienna

Year: 2020
Authors:

C. Frias Gomes1, C. Neto Nascimento1, F. Pereira2, A. Caldeira2, R. Sousa2, C. Arieira3, S. Xavier3, S. Monteiro3, F. Dias de Castro3, S. Leite3, J. Cotter3, A.A. Santos1, M. Cravo1, J. Torres1, C. Palmela1

1Surgery Department- Gastroenterology Division, Hospital Beatriz Ângelo, Loures, Portugal, 2Gastroenterology Department, Hospital Amato Lusitano, Castelo Branco, Portugal, 3Gastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal

P493 Segmental colectomy vs. extended colectomy for colonic Crohn’s disease: results from 112 consecutive patients

ECCO'20 Vienna

Year: 2020
Authors:

A. Frontali1, A. Chierici1, X. Treton2, L. Maggiori1, Y. Bouhnik2, Y. Panis3

1Beaujon Hospital, Colorectal Surgery, Clichy, France, 2Gastroenterology, Beaujon Hospital, Clichy, France, 3Department of Colorectal Surgery, APHP Beaujon, Clichy, France

P494 The efficacy and safety of adalimumab for patients with moderately to severely active ulcerative colitis and predictors of response in Korea

ECCO'20 Vienna

Year: 2020
Authors:

S. Shin Shin1, S.J. Park2, Y. Kim1, J.P. Im3, H.J. Kim4, K.M. Lee5, J.W. Kim6, S.A. Jung7, J. Lee8, S.B. Kang9, S.J. Shin10, E.S. Kim11, Y.S. Kim12, T.O. Kim13, H.S. Kim14, D.I. Park15, H.K. Kim16, E.S. Kim17, Y.H. Kim18, D.H. Kim19, D. Teng20, J.H. Kim1, W.Y. Kim1, C.H. Choi1

1Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea, 2Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea, 3Department of Internal medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, 4Department of Gastroenterology, Kyung Hee University Hospital, Seoul, Republic of Korea, 5Department of Gastroenterology, The Catholic University of Korea St. Vincent’s Hospital, Suwon, Republic of Korea, 6Department of Gastroenterology, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea, 7Department of Gastroenterology, Ewha Womans University Hospital, Seoul, Republic of Korea, 8Department of Internal Medicine, Chosun University College of Medicine, Gwagju, Republic of Korea, 9Department of Gastroenterology, The Catholic University of Korea Daejeon ST. Mary’s Hospital, Daejeon, Republic of Korea, 10Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea, 11Department of Gastroenterology, Korea University Anam Hospital, Seoul, Republic of Korea, 12Department of Gastroenterology, Inje University Seoul Paik Hospital, Seoul, Republic of Korea, 13Department of Gastroenterology, Inje University Haeundae Paik Hospital, Busan, Republic of Korea, 14Department of Gastroenterology, Chonnam National University Hospital, Gwagju, Republic of Korea, 15Department of Internal Medicine, Sungkyunkwan University School of Medicine- Kangbuk Samsung Hospital, Seoul, Republic of Korea, 16Department of Gastroenterology, Inha University Hospital, Incheon, Republic of Korea, 17Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea, 18Department of Medicine, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea, 19Abbvie Ltd., Abbvie Ltd., Seoul, Republic of Korea, 20AbbVie Pte. Ltd., AbbVie Pte. Ltd., Singapore, Singapore

P495 Usefulness of a capsule endoscopy scoring system in understanding the disease state of Crohn’s disease

ECCO'20 Vienna

Year: 2020
Authors:

T. Omori, H. Kambayashi, S. Murasugi, A. Ito, M. Yonezawa, K. Tokushige

Institute of Gastroenterology, Tokyo Women’s Medical University, Tokyo, Japan

P496 Feasibility and safety of single incision laparoscopic surgery for patients with complex Crohn’s disease

ECCO'20 Vienna

Year: 2020
Authors:

Y. LI, B. Liu, D. Yao, L. Zheng, Z. Zhou, Y. Huang, Y. Duan

Department of Surgery, Shanghai Ninth People’s Hospital -Shanghai Jiaotong University School, Shanghai, China

P497 Is mucosal healing sufficient paramater for anti-TNF discontinuation?

ECCO'20 Vienna

Year: 2020
Authors:

T. Knezevic1, M. Milic2, A. Kalaba1, S. Sreckovic1, B. Stopic3, P. Svorcan1, S. Markovic1

1Department of Gastroenterology and Hepatology, University Hospital Medical Center ‘ Zvezdara’, Belgrade, Serbia, 2Department of Pathology, University Hospital Medical Center ‘ Zvezdara’, Belgrade, Serbia, 3Department of Nephrology, University Hospital Medical Center ‘ Zvezdara’, Belgrade, Serbia

P498 Loss of response of anti-TNF in Crohn’s disease patients single-centre experience

ECCO'20 Vienna

Year: 2020
Authors:

A. Atanassova, A.C. Georgieva, M. Mirchev

Medical University – Varna- Bulgaria, University Hospital St. Marina- Clinic of Gastroenterology, Varna, Bulgaria

P499 Objectively assessed disease activity during ustekinumab treatment in a nationwide real-life Crohn’s disease cohort

ECCO'20 Vienna

Year: 2020
Authors:

C.G. af Björkesten1, T. Ilus2, T. Hallinen3, E. Soini3, A. Eberl1, K. Hakala4, M. Heikura5, E. Hirsi6, A. Jussila2, M. Kellokumpu7, R. Koskela8, I. Koskinen9, V. Moilanen10, C. Nielsen11, U. Nieminen1, H. Nuutinen12, M. Heikkinen13, U.M. Suhonen14, J. Tillonen15, K. Utriainen16, I. Vihriälä17, C. Wennerström18,19, A. Borsi20, R. Nissinen21, M. Koivunen21, T. Sipponen1

1University of Helsinki and Helsinki University Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland, 2Tampere University Hospital, Tampere University Hospital, Tampere, Finland, 3ESiOR Oy, ESiOR Oy, Kuopio, Finland, 4Kanta-Häme Central Hospital, Kanta-Häme Central Hospital, Hämeenlinna, Finland, 5North Karelia Central Hospital, North Karelia Central Hospital, Joensuu, Finland, 6South Karelia Central Hospital, South Karelia Central Hospital, Lappeenranta, Finland, 7Lapland Central Hospital, Lapland Central Hospital, Rovaniemi, Finland, 8Oulu University Hospital, Oulu University Hospital, Oulu, Finland, 9Central Finland Central Hospital, Central Finland Central Hospital, Jyväskylä, Finland, 10Satakunta Central Hospital, Satakunta Central Hospital, Pori, Finland, 11Vaasa Central Hospital, Vaasa Central Hospital, Vaasa, Finland, 12Turku University Hospital, Turku University Hospital, Turku, Finland, 13Kuopio University Hospital, Kuopio University Hospital, Kuopio, Finland, 14Kainuu Central Hospital, Kainuu Central Hospital, Kajaani, Finland, 15Päijät-Häme Central Hospital, Päijät-Häme Central Hospital, Lahti, Finland, 16Turku University Hospital- Salo Hospital, Turku University Hospital- Salo Hospital, Salo, Finland, 17Central Ostrobothnia Central Hospital, Central Ostrobothnia Central Hospital, Kokkola, Finland, 18Janssen Cilag AB, Medical Affairs, Solna, Sweden, 19Statens Serum Institut, Department of Epidemiology Research, Copenhagen, Denmark, 20Janssen Cilag Limited, emea hemar, High Wycombe, UK, 21Janssen Cilag Oy, Medical Affairs, Espoo, Finland

P500 Adiposity among IBD patients

ECCO'20 Vienna

Year: 2020
Authors:

M. Bletsa1, A. Karachaliou2, G. Kokkotis3, M.M. Tsoutska1, S. Andoniadi2, I. Papaconstantinou4, M. Kontogianni2, G. Bamias3

1Nutrition and Dietetic Department, Sotiria General Hospital, Athens, Greece, 2Department of Nutrition and Dietetics, Harokopio University, Athens, Greece, 3GI Unit- 3rd Department of Internal Medicine, Sotiria General Hospital, Athens, Greece, 42nd Department of Surgery, Aretaieion Hospital, Athens, Greece

P501 Thiopurine withdrawal in patients with Crohn’s disease: the SURESTE study

ECCO'20 Vienna

Year: 2020
Authors:

E. Sánchez Rodríguez1, R. Sánchez Aldehuelo1, J. Guardiola2, A. Gutiérrez Casbas3, E. Domènech4, F. Bermejo5, M. Van-Domselaar6, F. Mesonero Gismero1, G. Suris2, R. Muñoz Perez3, M. Mañosa4, L. Jiménez Márquez5, A. Algaba García5, A. López sanroman1, SURESTE

1Hospital Universitario Ramón y Cajal, Servicio de Gastroenterologia y Hepatología, Madrid, Spain, 2Hospital Universitari de Bellvitge, Servicio de Aparato Digestivo, Barcelona, Spain, 3Hospital General Universitario de Alicante, Servicio Medicina Digestiva, alicante, Spain, 4Hospital Universitari Germans Trias i Pujol, Servicio de Aparato Digestivo, Badalona, Spain, 5Hospital Universitario de Fuenlabrada, Servicio de Aparato Digestivo, madrid, Spain, 6Hospital Universitario de Torrejón., Servicio de Aparato Digestivo, Madrid, Spain

P502 Tumour necrosis factor antagonists are superior to anti-integrin and anti-IL-12/23 therapies for preventing postoperative recurrence in adult Crohn’s disease patients requiring postoperative therapy

ECCO'20 Vienna

Year: 2020
Authors:

T. Nakamura1, R. Shah2, M. Sachs3, S. Chang4, D. Hudesman4, B. Click5, J. Axelrad4

1New York University Medical Center, Medicine, New York, USA, 2Cleveland Clinic Medical Center, Medicine, Cleveland, USA, 3Karolinska, Clinical Epidemiology, Solna, Sweden, 4Gastroenterology and Hepatology, New York University Medical Center, New York, USA, 5Gastroenterology- Hepatology- and Nutrition, Cleveland Clinic Medical Center, Cleveland, USA