P701: Compositional and functional alterations of the gut microbiome are associated with impaired intestinal permeability in healthy relatives of patients with Crohn's diseaseECCO'22Year: 2022
Authors: Leibovitzh, H.(1);Lee, S.H.(1);Xue, M.(1);Raygoza Garay, J.A.(1);Hernandez-Rocha, C.(1);Madsen, K.L.(2);Meddings, J.B.(3);Guttman, D.S.(4);Espin-Garcia, O.(5);Smith, M.I.(6);Goethel, A.(6);Moayyedi, P.(7);Steinhart, A.H.(1);Panancionne, R.(8);Huynh, H.(9);Jacobson, K.(10);Aumais, G.(11);Mack, D.R.(12);Abreu, M.(13);Bernstein, C.N.(14);Marshall, J.K.(15);Turner, D.(16);Xu, W.(5);Turpin, W.(1);Croitoru, K.(1);
(1)Zane Cohen Centre for Digestive Diseases- Mount Sinai Hospital, Division of Gastroenterology & Hepatology- Temerty Faculty of Medicine- University of Toronto, Toronto, Canada;(2)University of Alberta, Department of Medicine- Division of Gastroenterology, Edmonton, Canada;(3)Cumming School of Medicine, Department of Medicine, Calgary, Canada;(4)Centre for the Analysis of Genome Evolution & Function- University of Toronto, Department of Cell & Systems Biology- University of Toronto, Toronto, Canada;(5)Dalla Lana School of Public Health- University of Toronto, Division of Biostatistics, Toronto, Canada;(6)Zane Cohen Centre for Digestive Diseases- Mount Sinai Hospital, Lunenfeld-Tanenbaum Research Institute, Toronto, Canada;(7)McMaster University- Farncombe Family Digestive Health Research Institute, Department of Medicine, Hamilton, Canada;(8)University of Calgary, Inflammatory Bowel Disease Clinic- Division of Gastroenterology and Hepatology of Gastroenterology, Calgary, Canada;(9)Faculty of Medicine and Dentistry- University of Alberta, Division of Gastroenterology and Nutrition- Department of Pediatrics, Edmonton, Canada;(10)Canadian Gastro-Intestinal Epidemiology Consortium, Children's Hospital- British Columbia Children's Hospital Research Institute- University of British Columbia, Vancouver, Canada;(11)Montreal University, Hôpital Maisonneuve-Rosemont- Department of Medicine, Montreal, Canada;(12)Children’s Hospital of Eastern Ontario and University of Ottawa, Division of Gastroenterology- Hepatology & Nutrition, Ottawa, Canada;(13)University of Miami Miller School of Medicine, Department of Medicine- Division of Gastroenterology-Crohn's and Colitis Center, Miami, United States;(14)University of Manitoba Inflammatory Bowel Disease Clinical and Research Centre, Department of Internal Medicine- Max Rady College of Medicine- Rady Faculty of Health sciences- University of Manitoba, Winnipeg, Canada;(15)Farncombe Family Digestive Health Research Institute, Department of Medicine- McMaster University, Hamilton, Canada;(16)The Hebrew University of Jerusalem, The Juliet Keidan Institute of Pediatric Gastroenterology and Nutrition- Shaare Zedek Medical Center, Jerusalem, Israel;Submitted on behalf of the CCC-GEM Consortium
P702: Faecal Microbiota Transplantation Sculpts the faecal and mucosal microbial and metabolomic profiles in patients with Ulcerative ColitisECCO'22Year: 2022
Authors: Bajaj, A.(1);Markandey, M.(1);Singh, M.(1);Virmani, S.(1);Vuyyuru, S.K.(1);Kante, B.(1);Thirunavukkarasu, R.(2);Verma, M.(1);Kumar, P.(1);Kshetrapal, P.(2);Makharia, G.(1);Gupta, D.(3);Kedia, S.(1);Ahuja, V.(1);
(1)All India Institute of Medical Sciences, Department of Gastroenterology and Human Nutrition, New Delhi, India;(2)Translational Health Science and Technology Institute, NCR Biotech Science Cluster, Faridabad 121001, India;(3)International Centre for Genetic Engineering and Biotechnology ICGEB, International Centre for Genetic Engineering and Biotechnology ICGEB, New Delhi, India;
P703: Gut bacteria composition and familiality echo Inflammatory Bowel Disease type and pathological spectrumECCO'22Year: 2022
Authors: Martinez-Gili, L.(1);Gordon, H.(2);Blad, W.(2);McDonald, J.A.K.(1);Holmes, E.(1);Marchesi, J.R.(1);Harbord, M.(2);
(1)Imperial College London, Department of Metabolism Digestion and Reproduction, London, United Kingdom;(2)Royal London Hospital, Department of Gastroenterology, London, United Kingdom;
P704: Bifidobacterium longum species protect murine colitis through different activation repertoires of immune cellsECCO'22Year: 2022
Authors: Kim, J.H.(1,2);I Seul, P.(1,2);Mijeong, S.(1,2);YooJin, S.(1,2);Kibeom, K.(1,2);Hyun Woo, M.(1,2);Tae Il, K.(1,2);Won Ho, K.(1,2);Seung Won, K.(1,2,3);Jae Hee, C.(1,2,3);
(1)Yonsei University College of Medicine, Internal Medicine and Institute of Gastroenterology, Seoul, Korea- Republic Of;(2)Yonsei University College of Medicine, Brain Korea 21 PLUS Project for Medical Science, Seoul, Korea- Republic Of;(3)Yonsei University College of Medicine, Severance Biomedical Science Institute, Seoul, Korea- Republic Of;
P705: The effects of commonly consumed dietary fibres on the gut microbiome and its fibre fermentative capacity in adults with inflammatory bowel disease in remissionECCO'22Year: 2022
Authors: Gerasimidis, K.(1);Nichols, B.(1);McGowan, M.(1);Svolos, V.(1);Papadopoulou, R.(1);Kokkorou, M.(1);Rebull, M.(1);Bello Gonzalez, T.(1);Hansen, R.(1);Russell, R.K.(1);Gaya, D.R.(1);
(1)Glasgow Royal Infirmary New Lister Building, Department of Human Nutrition- School of Medicine- College of Medical- Veterinary and Life Sciences, Glasgow, United Kingdom;
P706: A distinct subset of tissue-resident Th17 cells expands in the inflamed intestines of Crohn’s Disease patients and responds to colitogenic bacteriaECCO'22Year: 2022
Authors: ParoniPhD, M.(1);Leccese, G.(1);Ranzani, V.(2);Pagani, M.(3);Landini, P.(1);Vecchi, M.(4);Abrignani, S.(2);Facciotti, F.(5);Caprioli, F.(4);Geginat, J.(2);
(1)University of Milan, Department of Biosciences, Milano, Italy;(2)INGM-National Institute of Molecular Genetics “Romeo ed Enrica Invernizzi”, INGM-National Institute of Molecular Genetics “Romeo ed Enrica Invernizzi”, Milano, Italy;(3)FIRC Institute of Molecular Oncology IFOM- 20139 Milan- Italy, FIRC Institute of Molecular Oncology IFOM- 20139 Milan- Italy, Milano, Italy;(4)Gastroenterology and Endoscopy Unit- Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Gastroenterology and Endoscopy Unit- Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy;(5)Department of Experimental Oncology- European Institute of Oncology-, Department of Experimental Oncology- European Institute of Oncology-, Milano, Italy;
P707: Microbial signature of the colon is not associated with response to vedolizumab in Crohn’s diseaseECCO'22Year: 2022
Authors: HagemanMD, I.(1,2);Joustra, V.(1);Li Yim, A.(2,3);Davids, M.(4);Henneman, P.(3);Hakvoort, T.(2);Probert, F.(5);Satsangi, J.(6);D'Haens, G.(1);De Jonge, W.(2);
(1)Amsterdam UMC- University of Amsterdam, Department of Gastroenterology & Hepatology, Amsterdam, The Netherlands;(2)Amsterdam UMC- University of Amsterdam, Tytgat institute for for Liver and Intestinal Research, Amsterdam, The Netherlands;(3)Amsterdam UMC- University of Amsterdam, Genome Diagnostics Laboratory- Department of Human Genetics, Amsterdam, The Netherlands;(4)Amsterdam UMC- University of Amsterdam, Laboratory of Experimental Vascular Medicine- Academic Medical Center, Amsterdam, The Netherlands;(5)Oxford University, Department of Chemistry- Chemistry Research Laboratory- Mansfield Road, Oxford, United Kingdom;(6)Oxford University, Translational Gastroenterology Unit- NIHR Oxford Biomedical Research Centre- Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom;On behalf of the EPIC-Pioneer consortium
P709: Distinct Pattern of Gut Microbial Dysbiosis in Crohn's Disease and Intestinal Tuberculosis - A Machine Learning-based classification modelECCO'22Year: 2022
Authors: Markandey, M.(1);Bajaj, A.(1);Vuyyuru, S.K.(1);Mohta, S.(1);Singh, M.(1);Verma, M.(1);Kumar, S.(1);Kante, B.(1);Kumar, P.(1);Makharia, G.(1);Kedia, S.(1);Ahuja, V.(1);
(1)All India Institute of Medical Sciences, Department of Gastroenterology and Human Nutrition, New Delhi, India;
P711: Stool microbiome communities predict remission in pediatric Crohn’s disease patients even after start of treatmentECCO'22Year: 2022
Authors: VerburgtMD, C.(1);Dunn, K.A.(2);Bielawski, J.P.(3);Otley, A.R.(4);Heyman, M.B.(5);Sunseri, W.(6);Shouval, D.(7);Levine, A.(8);de Meij, T.(1);Hyams, J.S.(9);Denson, L.A.(10);Kugathasan, S.(11);Benninga, M.A.(1);de Jonge, W.J.(12);Van Limbergen, J.E.(1);
(1)Emma Children’s Hospital- Amsterdam University Medical Centres, Department of Paediatric Gastroenterology and Nutrition, Amsterdam, The Netherlands;(2)Dalhousie university, Department of Biology, Halifax, Canada;(3)Dalhousie university, Department of Mathematics and Statistics, Halifax, Canada;(4)Dalhousie university, Department of Paediatrics, Halifax, Canada;(5)Department of Paediatrics, UCSF Benioff Children’s Hospital- University of California, San Francisco, United States;(6)UPMC Children’s Hospital of Pittsburgh, Department of Paediatrics, Pittsburgh, United States;(7)Schneider Children’s Medical Center of Israel, Institute of Gastroenterology- Nutrition and Liver Diseases, Petah Tikva, Israel;(8)Wolfson Medical Centre- Holon- Israel- Sackler School of Medicine- Tel Aviv University, Paediatric Gastroenterology and Nutrition Unit, Tel Aviv, Israel;(9)Connecticut Children’s Medical Center, Division of Digestive Diseases- Hepatology and Nutrition, Hartford, United States;(10)Cincinatti Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Department of Paediatrics, Cincinnati, United States;(11)Emory University, Department of Paediatrics, Atlanta, United States;(12)Amsterdam University Medical Centers- University of Amsterdam, Tytgat Institute for Liver and Intestinal Research- Amsterdam Gastroenterology Endocrinology and Metabolism, Amsterdam, The Netherlands;
P712: Fungal microbiota composition in Inflammatory Bowel Disease patients in a Norwegian cohort: characterization of disease phenotypes and correlation with clinical activity and disease course.ECCO'22Year: 2022
Authors: Catalàn-Serrax, I.(1,2,3);Thorsvik, S.(3,4);Beisvag, V.(2);Bruland, T.(2);Underhill, D.(3,5,6);Sandvik, A.K.(2,3,4);Van Beelen Granlund, A.(2,3,4);
(1)Levanger Hospital- Nord-Trøndelag Hospital Trust- Department of Medicine- Gastroenterology- Levanger- Norway., Department of Gastroenterology, Trondheim, Spain;(2)Norwegian University of Science and Technology, Department of Clinical and Molecular Medicine, Trondheim, Norway;(3)Norwegian University of Science and Technology- Centre for Molecular Inflammation Research CEMIR- Trondheim- Norway., Department of Clinical and Molecular Medicine, Trondheim, Norway;(4)St Olav’s Hospital, Gastroenterology, Trondheim, Norway;(5)Cedars-Sinai Medical Center, F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Los Angeles, United States;(6)Cedars-Sinai Medical Center, Research Division of Immunology, Los Angeles, United States;Inflammatory Bowel Disease Research Group. NTNU
P713: Gut microbiota alterations after bowel preparation amongst inflammatory bowel disease patientsECCO'22Year: 2022
Authors: Rutka, M.(1);Szántó, K.(1);Bacsur, P.(1);Resál, T.(1);Jójárt, B.(2);Bálint, A.(1);Ari, E.(3);Kintses, B.(4);Fehér, T.(4);Asbóth, A.(5);Pigniczki, D.(1);Bor, R.(1);Fábián, A.(1);Farkas, K.(1);Maléth, J.(2);Szepes, Z.(1);Molnár, T.(1);
(1)Szent-Györgyi Albert Medical School- University of Szeged, Department of Medicine, Szeged, Hungary;(2)Hungarian Academy of Science- University of Szeged, Momentum Epithelial Cell Signaling and Secretion Research Group, Szeged, Hungary;(3)Institute of Biochemistry- Biological Research Centre, Synthetic and Systems Biology Unit, Szeged, Hungary;(4)Hungarian Centre of Excellence of Molecular Medicine- University of Szeged, Translational Microbiology Research Group, Szeged, Hungary;(5)Eötvös Lóránd University, Department of Genetics, Budapest, Hungary;
P714: Comparison of intestinal microbiota profiles of faecal samples, rectal swabs and mucosal biopsies in patients with Inflammatory Bowel Disease. A multicentre, observational study.ECCO'22Year: 2022
Authors: Van Rossen, T.(1);van den Hoek, K.(2);Budding, A.(3);van Bodegraven, A.(4);
(1)Amsterdam UMC, Medical Microbiology & Infection Control, Amsterdam, The Netherlands;(2)Amsterdam UMC, Gastroenterology & Hepatology, Amsterdam, The Netherlands;(3)inBiome, inBiome, Amsterdam, The Netherlands;(4)Zuyderland Medical Center, Gastroenterology & Hepatology, Sittard-Geleen, The Netherlands;
P716: Exclusive Enteral Nutrition refurbishes beneficial gut microbiota in patients with Acute Severe Ulcerative ColitisECCO'22Year: 2022
Authors: Bajaj, A.(1);Markandey, M.(1);Sahu, P.(1);Vuyyuru, S.K.(1);Kante, B.(1);Kumar, P.(1);Singh, N.(1);Gupta, A.(1);Singh, M.(1);Verma, M.(1);Makharia, G.(1);Kedia, S.(1);Ahuja, V.(1);
(1)All India Institute of Medical Sciences, Department of Gastroenterology and Human Nutrition, New Delhi, India;
P717: Faecal Microbiota Transplant in Ulcerative Colitis (FMTUC) – A randomised clinical trial feasibility studyECCO'22Year: 2022
Authors: Jitsumura, M.(1,2);Cunningham , A.(1);Hitchings, M.D.(3);Wilkinson, T.(3);Kinross, J.(4);Row, P.(5);Davies, A.(6);Dean Anthony, H.(1);
(1)Singleton Hospital, Department of Colorectal Surgery, Swansea, United Kingdom;(2)Poole Hospital, General Surgery, Poole, United Kingdom;(3)Swansea University Medical School, Medical Microbiology and Infectious Diseases, Swansea, United Kingdom;(4)St. Mary's Hospital- Imperial College London, Department of Surgery and Cancer, London, United Kingdom;(5)Swansea University Medical School, Biochemistry Group, Swansea, United Kingdom;(6)Swansea University Medical School- Singleton Hospital, Public Health Wales Microbiology, Swansea, United Kingdom;
P718: Characterization of microbiota and metabolomic profile in human colonic surgical resections of UC patientsECCO'22Year: 2022
Authors: Bauset, C.(1);Carda-Diéguez, M.(2);Buetas, E.(2);Lis-López, L.(1);Navarro, F.(3);Ortiz-Masiá, D.(4);Calatayud, S.(1);Barrachina, M.D.(1);Mira, Á.(2);Cosín-Roger, J.(5);
(1)Universitat de Valencia, Pharmacology, Valencia, Spain;(2)FISABIO, Genomics and Health Department, Valencia, Spain;(3)Hospital de Manises, Colorectal surgery, Valencia, Spain;(4)Universitat de Valencia, Medicine, Valencia, Spain;(5)FISABIO, Unidad Mixta Facultad de Medicina-Hospital Dr. Peset, Valencia, Spain;
P720: Similar risk of infection with SARS-CoV-2 in immunocompromised and immunocompetent patients with inflammatory bowel disease and healthy controlsECCO'22Year: 2022
Authors: Kante, B.(1);Vuyyuru, S.K.(1);Gupta, R.(2);Dwivedi, T.(2);Kumar, P.(1);Mundhra, S.(1);Golla, R.(1);Virmani, S.(1);Verma, M.(1);Makharia, G.(1);Ahuja, V.(1);Kedia, S.(1);
(1)AIIMS, Gastroenterology, NEW DELHI, India;(2)AIIMS, Lab Oncology, New Delhi, India;
