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P103 The treatment effect of tonsil-derived mesenchymal stem cells (T-MSCs) via regulating programmed death-1/programmed death ligand-1 (PD-1/PD-L1) in ulcerative colitis

ECCO'20 Vienna

Year: 2020
Authors:

E.M. Song, Y.H. Joo, J.Y. Lim, A.R. Choe, C.H. Tae, C.M. Moon, S.E. Kim, H.K. Jung, K.N. Shim, S.A. Jung

Department of Gastroenterology, Ewha Womans University College of Medicine, Seoul, Republic of Korea

P104 Defective metabolism mediates NK cell dysfunction in inflammatory bowel disease (IBD)

ECCO'20 Vienna

Year: 2020
Authors:

V. Zaiatz Bittencourt1, E. Ryan2, F. Jones1, G. Doherty1

1School of Medicine, University College Dublin, Dublin, Ireland, 2Department of Biological Sciences, University of Limerick, Dublin, Ireland

P105 Glutathione S-transferase theta 1 protects against colitis through goblet cell differentiation via interleukin-22

ECCO'20 Vienna

Year: 2020
Authors:

J.H. Kim1, J.B. Ahn2, D.H. Kim1, S. Kim3, H.W. Ma1, X. Che1, D.H. Seo1, T.I. Kim1, W.H. Kim3, J.H. Cheon1, S.W. KimResearch Professor1

1Yonsei University College of Medicine, Brain Korea 21 PLUS Project for Medical Science, Seoul, Republic of Korea, 2Yonsei University College of Medicine, Department of Medicine, Seoul, Republic of Korea, 3Yonsei University College of Medicine, Department of Internal Medicine and Institute of Gastroenterology, Seoul, Republic of Korea

P106 Depressive symptoms and anxiety and their screening in IBD patients: performance of the distress thermometer in Italian IBD patients

ECCO'20 Vienna

Year: 2020
Authors:

C. Canaletti1, F. Colombo2, A. Dessì2, E. Geccherle3, A. Tongiorgi4, P. Cai5, F. Giudici6, G. Mocci7, F.M. Onidi7, A. Orlando8, M.G. Mortillaro8, F. Bossa9, G. Martino9, M. Placentino9, L. Guidi10, D. Pugliese10, L. Tiberio10, F. Costa4, G. Deledda3, A. Geccherle3, A. Paolini1, C.F. Tonello1, G.M. Pecoraro1, F. Monica1

1Asuits Cattinara Hospital, Gastroenterology, Trieste, Italy, 2Istituto Milanese di Psicoterapia Cognitivo Comportamentale - IMIPSI, Psychology, Milano, Italy, 3Ospedale IRCCS ‘Sacro Cuore - Don Calabria’ Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Classificato e Presidio Ospedaliero Accreditato - Regione Veneto, Gastroenterology, Verona, Italy, 4Azienda Ospedaliero Universitaria di Pisa – AOUP, Gastroenterology, Pisa, Italy, 5Ospedale San Martino, Genova, Psychology, Genova, Italy, 6Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, VascularSciences and Public Health, University of Padova, Biostatistics, Padova, Italy, 7Ospedale S. Michele Brotzu, Gastroenterology, Cagliari, Italy, 8Ospedali Riuniti Villa Sofia-Cervello, Internal Medicine, Palermo, Italy, 9Ospedale Regionale Casa Sollievo della Sofferenza IRCCS di San Giovanni Rotondo, Gastroenterology, San Giovanni Rotondo, Italy, 10IBD Unit Presidio Columbus-Fondazione Policlinico Universitario A. Gemelli IRCCS e Università Cattolica del Sacro Cuore, Gastroenterology, Roma, Italy

P107 The expression and regulation of Oncostatin M and its receptor in intestinal inflammation

ECCO'20 Vienna

Year: 2020
Authors:

R. Cineus1,2, D. Boesel1,2, S. Hainbuch1,2, C. Jukes1,2, Y.H. Hsieh1,2, J. Reich1,2, Z. Borek1,2, A. Kuehl1,3, A.N. Hegazy PhD, MD1,2

1IBDome-DE Investigators, Charité – University Medicine Berlin, CBF and German Rheumatism Research Center-Berlin, Department of Gastroenterology, Infectiology and Rheumatology, Berlin, Germany, 2Deutsches Rheuma-Forschungszentrum, ein Institut der Leibniz-Gemeinschaft, Inflammatory Mechanisms Group, Berlin, Germany, 3Charité-Universitätsmedizin Berlin, iPath.Berlin-Immunopathology for Experimental Models, Berlin, Germany

P108 The importance of developing consensus-driven clinical data standards for Crohn’s disease to amplify data

ECCO'20 Vienna

Year: 2020
Authors:

J. Owen, R. Baker

CDISC, Standards Development, Austin, USA

P109 Construction of a suite of computable biological network models focused on inflammatory bowel disease

ECCO'20 Vienna

Year: 2020
Authors:

P.A. Ruiz Castro, H. Yepiskoposyan, J. Szostak, M. Talikka, J. Hoeng

PMI, Systems toxicology, Neuchatel, Switzerland

P110 Identification of the tryptophan metabolite 3-hydroxyanthranilic acid as a novel tool for the differentiation of Crohn’s disease phenotypes

ECCO'20 Vienna

Year: 2020
Authors:

M. Huhn1, M. Herrero San Juan1, B. Melcher2, C. Dreis1, K. Schmidt1, J.M. Pfeilschifter1, M. Vieth2, J. Stein3, H.H. Radeke1

1Pharmazentrum Frankfurt, Institute of Pharmacology and Toxicology, Frankfurt am Main, Germany, 2Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany, 3Department of Gastroenterology and Clinical Nutrition, DGD Clinics Sachsenhausen, Frankfurt am Main, Germany

P111 Elucidation of inflammatory infiltration of myenteric plexus in IBD

ECCO'20 Vienna

Year: 2020
Authors:

J.J. Wiese, A. Fascì, A.A. Kühl, B. Siegmund, M.S. Prüß, M. Schumann

Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Charité – Universitätsmedizin Berlin, Berlin, Germany

P112 Body composition and resting energy expenditure in IBD patients receiving biological therapy

ECCO'20 Vienna

Year: 2020
Authors:

D. Vranesic Bender1, L. Cengic2, D. Ljubas Kelecic1, I. Karas1, A. Grbin Hodžić3, V. Domislović3, M. Brinar3, M. Juričić1, Ž. Krznarić3

1University Hospital Zagreb, Unit of Clinical Nutrition, Zagreb, Croatia, 2Faculty of Food Technology and Biotechnology, Laboratory of Nutrition Science, Zagreb, Croatia, 3Department of Gastroenterology and Hepatology, University Hospital Zagreb, Zagreb, Croatia

P113 Serum adipokines as non-invasive biomarker in Crohn’s disease

ECCO'20 Vienna

Year: 2020
Authors:

L. Ortega Moreno1, A. Sanz-Garcia2, M.J. Fernández de la Fuente3, R. Arroyo Solera4, M. Chaparro5, S. Fernandez-Tome6, A.C. Marin7, I. Mora-Fernandez6, P. Fernandez4, M. Baldan-Martin7, D. Bernardo8,9, J.P. Gisbert5,9

1Universidad Autónoma de Madrid. Hospital Universitario de La Princesa, Medicina, Madrid, Spain, 2Unidad de Análisis de Datos. Hospital Universitario de La Princesa, Análisis de Datos, Madrid, Spain, 3Universidad de Alcalá., Farmacia, Alcalá de Henares Madrid, Spain, 4Instituto de Medicina Molecular Aplicada IMMA. Universidad San Pablo CEU., Medicina, Madrid, Spain, 5Universidad Autónoma de Madrid. Hospital Universitario de La Princesa. CIBERehd., Medicina, Madrid, Spain, 6Hospital Universitario de La Princesa, Medicina, Madrid, Spain, 7Hospital Universitario de La Princesa. CIBERehd., Medicina, Madrid, Spain, 8Mucosal Immunolgy lab. Instituto de de Biología y Genética Molecular IBGM., Medicina, Valladolid, Spain, 9Both authors had equal contribution- as senior authors, Medicina, Madrid, Spain

P114 A screening tool for the early diagnosis of extraintestinal manifestations in inflammatory bowel disease: the EMAIL questionnaire

ECCO'20 Vienna

Year: 2020
Authors:

A. Busacca, G. Ingrassia Strano, E. Giuffrida, L. Guida, B. Scrivo, L. Carrozza, V. Calvaruso, M. Cappello

Gastroenterology and Hepatology Section, University of Palermo, PROMISE, Palermo, Italy

P115 Real-world experience of peri-operative treatments on surgical complications after Ileo-caecal resection in Crohn’s disease

ECCO'20 Vienna

Year: 2020
Authors:

S. Di Stefano1,2, C. Liefferinckx3, A. Cremer3, L. Amininejad3, A. Van Gossum3, J. Devière3, J. Van de Stadt4, D. Franchimont3, A. Buggenhout4

1Hôpital Erasme, Department of Gastroenterelogy, Brussels, Belgium, 2The Pancreas Institute. University of Verona. G.B. Rossi University, Gastroenterology and Digestive Endoscopy Unit, Verona, Italy, 3Hôpital Erasme, Gastroenterelogy, Brussels, Belgium, 4Hôpital Erasme, Clinic of Colorectal Surgery – Department of Digestive Surgery, Brussels, Belgium

P116 The occurrence of venous thromboembolisms in paediatric-onset IBD

ECCO'20 Vienna

Year: 2020
Authors:

M. Aardoom1, P. Kemos2, F.M. Ruemmele3, C.H. van Ommen4, N.M. Croft2, L. de Ridder1, On Behalf of the PIBD-SETQuality Consortium and PIBDnet

1Erasmus MC/Sophia Children’s Hospital, Department of Paediatric Gastroenterology, Rotterdam, The Netherlands, 2Centre for Immunobiology, Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, Department of Paediatric Gastroenterology, London, UK, 3Université Paris Descartes, Sorbonne Paris Cité, APHP, Hôpital Necker Enfants Malades, Department of Pediatric Gastroenterology, Paris, France, 4Erasmus Medical Center, Sophia Children’s Hospital, Department of Pediatric Hematology, Rotterdam, The Netherlands

P117 Biomarkers of extracellular matrix remodelling are associated with intestinal fibrosis assessed by magnetic resonance enterography and accumulated intestinal damage (Lémann index): the IBSEN study

ECCO'20 Vienna

Year: 2020
Authors:

J. Mortensen1, A.K. Lunder2, T. Manon-Jensen1, M.A. Karsdal1, M.J. Nielsen1, D.J. Leeming1, J.R. Hov3, A. Negård2,4, J. Jahnsen4,5, B. Moum4,6, M. Vesterhus7,8,9,10, M.L. Høivik11, V.A. Kristensen11

1Nordic Bioscience A/S, Department of Biomarkers and Research, Herlev, Denmark, 2Akershus University Hospital, Department of Radiology, Lørenskog, Norway, 3University of Oslo, Department of Transplantation Medicine, Oslo, Norway, 4University of Oslo, Institute of Clinical Medicine, Oslo, Norway, 5Akershus University Hospital, Department of Gastroenterology, Lørenskog, Norway, 6University Hospital Oslo, Department of Gastroenterology, Oslo, Norway, 7Oslo University Hospital Rikshospitalet, Norwegian PSC Research Center, Oslo, Norway, 8Haraldsplass Deaconess Hospital, Department of Medicine, Bergen, Norway, 9University of Bergen, Department of Clinical Science, Bergen, Norway, 10Oslo University Hospital Rikshospitalet, Department of Transplantation Medicine, Oslo, Norway, 11Oslo University Hospital, Department of Gastroenterology, Oslo, Norway

P118 A comprehensive evaluation of mucosal redness in patients with ulcerative colitis by linked colour imaging

ECCO'20 Vienna

Year: 2020
Authors:

K. Uchiyama, M. Kubota, Y. Azuma, R. Yasuda, T. Shun, T. Takagi, Y. Naito, I. Yoshito

Kyoto Prefectural University Of Medicine, Department of Molecuar Gastroenterology and Hepatology, Kyoto, Japan

P119 Brain function and fatigue in patients with inflammatory bowel disease

ECCO'20 Vienna

Year: 2020
Authors:

A. Thomann1, M. Schmitgen2, D. Kmuche3, M. Griebe3, M. Ebert1, R.C. Wolf2, W. Reindl1

1Medical Faculty Mannheim, Heidelberg University, Department of Medicine II, Mannheim, Germany, 2Heidelberg University Hospital, Department of General Psychiatry, Heidelberg, Germany, 3Medical Faculty Mannheim, Heidelberg University, Department of Neurology, Mannheim, Germany

P120 Prevalence of endoscopic improvement and endoscopic remission according to patient reported outcomes in ulcerative colitis

ECCO'20 Vienna

Year: 2020
Authors:

P. Dulai1, S. Singh1, V. Jairath2, C. Ma3, N. Narula4, N. Vande Casteele1, L. Peyrin-Biroulet5, S. Vermeire6, G. D’Haens7, B. Feagan2, W. Sandborn1

1University of California San Diego, Gastroenterology, San Diego, USA, 2University of Western Ontario, Gastroenterology, London, Ontario, Canada, 3University of Calgary, Gastroenterology, Calgary, Alberta, Canada, 4McMaster University, Gastroenterology, Hamilton, Ontario, Canada, 5Nancy University Hospital, Gastroenterology, Nancy, France, 6University Hospitals Leuven, Gastroenterology, Leuven, Belgium, 7Academic Medical Center, Gastroenterology, Antilles, Amsterdam, The Netherlands

P121 Real-world use of the IBD disk tool in unselected cohorts of outpatients

ECCO'20 Vienna

Year: 2020
Authors:

N. Sharma1, E. Savelkoul2, B. Disney3, A. Shah4, S. De Silva5, S. Pattni6, M. Iacucci7, R. Cooney8, S. Ghosh9

1Institute of Immunology and Immunotherapy, University of Birmingham, Gastroenterology, Birmingham, UK, 2Radboudumc, Gastroenterology, Nijmegen, The Netherlands, 3University Hospitals Coventry and Warwickshire, Gastroenterology, Coventry, UK, 4The Royal Wolverhampton NHS Trust, Gastroenterology, Wolverhampton, UK, 5The Dudley Group NHS Foundation Trust, Gastroenterology, Dudley, UK, 6University Hospitals Of Leicester NHS Trust, Gastroenterology, Leicester, UK, 7Institute of Translational Medicine- Institute of Immunology and Immunotherapy, NIHR Biomedical Research Centre- University of Birmiingham, Birmingham, UK, 8Queen Elizabeth Hospital Birmingham, Gastroenterology, Birmingham, UK, 9Institute of Translational Medicine, Institute of Immunology and Immunotherapy, NIHR Birmingham Biomedical Research Centre, Birmingham, UK

P122 High correlation between faecal calprotectin and a Novel Integral Index for evaluating disease activity in ulcerative colitis patients

ECCO'20 Vienna

Year: 2020
Authors:

J.K. Yamamoto-Furusho MD, PhD1, E.A. Mendieta-Escalante2

1National Institute of Medical Science and Nutrition Salvador Zubiran, Department of Gastroenterology, Mexico City, Mexico, 2IBD Clinic, Department of Gastroenterology, Instituto Nacional de Ciencias Medicas y Nutricion, Gastroenterology, Mexico, Mexico