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P083 Characterisation of T-cell receptor repertoire patterns of circulating a4b7 positive memory T cells in ulcerative colitis

ECCO'20 Vienna

Year: 2020
Authors:

A. Gamliel, L. Werner, N. Salamon, M. Pinsker, B. Weiss, D. Shouval

Tel-HaShomer Sheba Medical Center Edmond and Lily Safra Childrens Hospital, Paediatric Gastroenterology Unit, Ramat-Gan, Israel

P084 Cannabis use promotes lymphocyte responsiveness and modifies T-cell signalling in adolescent IBD patients

ECCO'20 Vienna

Year: 2020
Authors:

M. Sanctuary1, C. Wilkinson2, A. Jones2, B. Murphy3, E. Hoffenberg3, C. Collins4

1University of Colorado Denver, Mucosal Inflammation Program, Pediatrics, Aurora, USA, 2University of Colorado, Mucosal Inflammation Program, Pediatrics, Aurora, USA, 3Children’s Hospital Colorado, Pediatrics, Aurora, USA, 4University College Dublin, Pharmacology, Dublin, Ireland

P085 Deep profiling of the circulating immune cell landscape in inflammatory bowel disease by mass cytometry

ECCO'20 Vienna

Year: 2020
Authors:

V. Horn1,2, Z. Borek1,2, E. Mantzivi1, M. Urbicht3, D. Boesel1,2, S. Baumgart3, E. Sonnenberg1, D. Lissner1, B. Siegmund1, H. Mei3, A.N. Hegazy MD, PhD1

1Charité – University Medicine Berlin- CBF and German Rheumatism Research Center-Berlin, Department of Gastroenterology, Infectiology and Rheumatology, Berlin, Germany, 2Deutsches Rheuma-Forschungszentrum, ein Institut der Leibniz-Gemeinschaft, Inflammatory Mechanisms Group, Berlin, Germany, 3Deutsches Rheuma-Forschungszentrum, ein Institut der Leibniz-Gemeinschaft, Mass Cytometry Group, Berlin, Germany

P086 Identification of constitutive modifications in plasma cells and B lymphocytes in patients with inflammatory bowel disease

ECCO'20 Vienna

Year: 2020
Authors:

A.C. Marin1, S. Fernández-Tomé1, L. Ortega Moreno2, V. Martin Dominguez3, S. Casabona3, I. Becerro3, I. Mora-Gutiérrez1, I. Villacañas-Gil1, M. Baldan-Martin1, J.A. Moreno-Monteagudo3, C. Santander2, M. Chaparro2, D. Bernardo1,4,5, J.P. Gisbert2,5

1Hospital Universitario de La Princesa, Department of Gastroenterology, IIS-IP and CIBERehd, Madrid, Spain, 2Hospital Universitario de La Princesa, Department of Gastroenterology, IIS-IP and CIBERehd. Departamento de Medicina. Universidad Autónoma de Madrid., Madrid, Spain, 3Hospital Universitario de La Princesa, Department of Gastroenterology, IIS-IP, Madrid, Spain, 4Instituto de Biología y Genética Molecular IBGM, Mucosal Immunology Lab. Universidad de Valladolid-CSIC., Valladolid, Spain, 5Both authors had equal contribution, as senior authors, Madrid, Spain

P087 Biomarkers of elastin degradation differentiate between clinically inactive and active disease in ulcerative colitis patients

ECCO'20 Vienna

Year: 2020
Authors:

M. Pehrsson1, V. Domislović2, M.A. Karsdal1, M. Brinar2, A. Barisic3, Z. Krznaric2, T. Manon-Jensen1, J.H. Mortensen1

1Nordic Bioscience A/S, Biomarkers and Research, Herlev, Denmark, 2University Hospital Centre Zagreb, Department of Gastroenterology and Hepatology, Zagreb, Croatia, 3University Hospital Centre Zagreb, Department for Clinical Nutrition, Zagreb, Croatia

P088 TLR3 ameliorates colitis-associated colon tumourigenesis in mice

ECCO'20 Vienna

Year: 2020
Authors:

Y.K. Jun1,2,3, S.J. Koh1,3, H.W. Gang4, K.Y. Chung1,3, J.M. Han1, J.W. Kim1,3, B.G. Kim1, K.L. Lee1, J.P. Im2, J.S. Kim2

1Division of Gastroenterology and Hepatology, Department of Internal Medicine, SMG-SNU Boramae medical Center, Seoul, Republic of Korea, 2Division of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, 3Laboratory of Intestinal Mucosa and Skin Immunology, SMG-SNU Boramae medical Center, Seoul, Republic of Korea, 4Division of Gastroenterology- Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Republic of Korea

P089 Immune system cell differences between Crohn’s disease and ulcerative colitis patients in remission under anti TNF treatment