¹Department of Animal and Avian Sciences, University of Maryland College Park, College Park, MD, USA, ²Innovate Biopharmaceuticals Inc., Innovate Biopharmaceuticals Inc., Raleigh, NC, USA, ³North Carolina State University, Department of Clinical Sciences, Raleigh, NC, USA

¹Department of Pediatrics, Department of Pediatrics, Medical University of Silesia, Katowice, Poland, ²Student Scientific Club, Department of Pediatrics, Medical University of Silesia, Katowice, Poland

¹Department of Surgery, University of Campinas, Campinas, Brazil, ²Department of Internal Medicine, University of Campinas, Campinas, Brazil

¹Department of Gastroenterology, Department of Digestive Diseases and Liver Transplantation, Clinical Institute Fundeni, Bucharest, Romania, ²Department of Gastroenterology, University Hospital CHU Liège, Liège, Belgium, ³Department of Gastroenterology and Hepatology, Elias Emergency Hospital, Bucharest, Romania

Tohoku University, Gastroenterology, Miyagiken Sendai City, Japan

¹Eastman Dental Institute, University College London, London, UK, ²UCLH Biomedical Research Centre, National Institute for Health Research, London, UK, ³Eastman Dental Hospital, University College London Hospital, London, UK, ⁴Biochemical Genetic Department, Kagoshima University, Kagoshima, Japan, ⁵Department of Gastroenterology, University College Hospital, London, UK, ⁶Department of Statistical Science, University College London, London, UK

CHA University, Gastroenterology, Seongnam-Si, Korea Republic of

¹Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, USA, ²School of Medicine, Department of Internal Medicine, Kyungpook National University- Daegu, Korea- Republic of, ³Gastroenterology Division, Cochin University Hospital, Paris, France, ⁴Calpro AS, Calpro AS, Lysaker, Norway, ⁵Division of Pediatric Gastroenterology and Hepatology, Icahn School of Medicine at Mount Sinai, New York, USA, ⁶Department of Obstetrics, Gynecology and Reproductive Sciences, Icahn School of Medicine at Mount Sinai, New York, USA, ⁷Department of Gastroenterology, University Hospital of Leuven, Leuven, Belgium, ⁸Gastroenterology Division, Hospital Beatriz Angelo, Loures, Portugal, ⁹Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA

¹Department of Medical Innovations, New Drug Research Division, Otsuka Pharmaceutical Co. Ltd., Tokushima, Japan, ²Pharmaceutical Planning Group, Otsuka Pharmaceutical Co., Ltd., Tokyo, Japan, ³Medical Regulatory Affairs Department, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

¹CHU of Liège and Laboratory of Translational Gastroenterology, GIGA-R, ULiège, Hepato-Gastroenterology and Digestive Oncology, Liège, Belgium, ²CHU of Liège, Anatomy and Pathology, Liège, Belgium, ³ULiège, Proteomics Facility of GIGA, Liège, Belgium, ⁴ULiège, Laboratory of Mass Spectrometry, CART, Liège, Belgium

Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland

¹Department of Biology, Gossamer Bio Inc., San Diego, USA, ²Department of Preclinical Research, Gossamer Bio Inc., San Diego, USA, ³Department of Clinical Development, Gossamer Bio Inc., San Diego, USA, ⁴Department of Research and Development, Gossamer Bio Inc., San Diego, USA

¹Department of Gastroenterology/Center for Advanced IBD Research and Treatment, Kitasato University Kitasato Institute Hospital, Tokyo, Japan, ²Department of Research, Kitasato University Kitasato Institute Hospital, Tokyo, Japan, ³Center for Advanced IBD Research and Treatment, Kitasato University Kitasato Institute Hospital, Tokyo, Japan, ⁴The Newcastle Cancer Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK, ⁵Department of Respiratory Medicine, Kitasato University Kitasato Institute Hospital, Tokyo, Japan, ⁶Department of Clinical Pharmacy, Center for Clinical Pharmacy and Sciences, Kitasato University School of Pharmacy, Tokyo, Japan

¹The Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK, ²Division of Pathology, Centre for Comparative Pathology, Cancer Research UK Edinburgh Centre, The Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK

¹Department of Biology, ChemoCentryx, Inc., Mountain View, CA, USA, ²Department of Chemistry, ChemoCentryx, Inc., Mountain View, CA, USA

¹IDIBAPS, Inflammatory Bowel Disease Unit, Barcelona, Spain, ²Ciberehd, Bioinformatics, Barcelona, Spain, ³Hospital Clinic de Barcelona, Gastroenterology, Barcelona, Spain, ⁴Wellcome Trust Sanger Institute, Bioinformatics, Hinxton, UK

Gastroenterology Department, Hospital Universitari Mútua Terrassa, Universitat de Barcelona, Terrassa. Centro de Investigación Biomédica en red de enfermedades hepáticas y digestivas CIBERehd, Gastroenterology Department, Terrassa, Spain

¹Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa IIS-IP, Universidad Autónoma de Madrid, and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBERehd, Gastroenterology, Madrid, Spain, ²CIC bioGUNE, CIBERehd, ProteoRed-ISCIII, Proteomics Platform, Derio, Spain, ³Biodonostia Research Institute. Donostia University Hospital and CIBERehd, Liver Diseases Group, San Sebastian, Spain

¹Department of Gastroenterology, Eulji University College of Medicine, Seoul, Korea- Republic of, ²Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea- Republic of Korea

¹Department of Biomedical Sciences, Humanitas University, Rozzano Milano, Italy, ²European Federation of Crohn’s and Ulcerative Colitis Associations, n/a, Brussels, Belgium, ³Takeda Pharmaceuticals International AG, Medical Affairs Europe and Canada, Zurich, Switzerland