¹Department of Gastroenterology, Gulhane Faculty of Medicine, Ankara, Turkey, ²Department of Infectious Diseases and Clinical Microbiology, Gulhane Faculty of Medicine, Ankara, Turkey

¹Department of Medicine, Imperial College London, London, UK, ²Inflammatory Bowel Disease Unit, St Mark’s Academic Institute, London, UK

¹Laboratory of Pediatrics, Division Gastroenterology and Nutrition, Erasmus University Medical Center, Sophia Children’s Hospital, Rotterdam, The Netherlands, ²Department of Pediatric Gastroenterology, Erasmus University Medical Center, Sophia Children’s Hospital, Rotterdam, The Netherlands, ³Departments of Immunology, University of Alabama at Birmingham, Birmingham, USA, ⁴Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands, ⁵Blizard Institute, Queen Mary University of London, London, UK, ⁶Service de Gastroentérologie, Sorbonne Paris Cité- APHP, Hôpital Necker Enfants Malades, Université Paris Descartes, Paris, France, ⁷Centre for Digestive Diseases, Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK, ⁸Department of Medicine, University of Alabama at Birmingham, Birmingham, USA

¹Klinik für Allgemeine Innere Medizin und Gastroenterologie, Klinikum Lüneburg, Lüneburg, Germany, ²Gastro Unit Section of Medicine, Hvidovre Hospital, Copenhagen, Denmark, ³Digestive Disease Center, Bispebjerg Hospital, Copenhagen, Denmark, ⁴Gastroenterology Unit, Department of Biomedical and Clinical Sciences, ‘Luigi Sacco’ University Hospital University of Milan, Milan, Italy, ⁵Ambroise Paré Hospital APHP-Paris Saclay, University INSERM U1173 Laboratoire d’Excellence INFLAMEX, Rheumatology Department, Paris, France, ⁶Department of Medical Affairs, Janssen-Cilag SARL, Issy-les-Moulineaux, France, ⁷Department of Medical Affairs, Janssen-Cilag Polska Sp. z o.o, Warsaw, Poland, ⁸Department of Medical Affairs, Janssen Scientific Affairs LLC, Horsham, PA, USA, ⁹Department of Medical Affairs, Janssen-Cilag B.V., Breda, The Netherlands, ¹⁰Department of Medical Affairs, Janssen-Cilag, Moscow, Russian Federation, ¹¹Gastroenterology Unit, Mauriziano Hospital, Turin, Italy, ¹²Department of Gastroenterology, Humanitas University, Milan, Italy, ¹³Clinical Center ISCARE, Clinical and Research Center for Inflammatory Bowel Diseases, Prague, Czech Republic, ¹⁴Ambulanzzentrum Gastroenterologie, Klinikum Lüneburg, Lüneburg, Germany

The Edinburgh IBD Unit, Gastroenterology, Western General Hospital, Edinburgh, UK

¹University of Calgary, Inflammatory Bowel Disease Center, Calgary, Canada, ²University of California San Diego, Gastroenterology, La Jolla, USA, ³Icahn School of Medicine at Mount Sinai, Gastroenterology, New York, USA, ⁴Janssen Research and Development- LLC, Immunology, Spring House, USA, ⁵Janssen Research and Development- LLC, Clinical Biostats, Spring House, USA, ⁶Nancy University Hospital, Gastroenterology, Nancy, France, ⁷Kyorin University School of Medicine, Internal Medicine, Tokyo, Japan, ⁸Humanitas Research Hospital, Gastroenterology, Milan, Italy

¹Humanitas University, Department of Gastroenterology, Milan, Italy, ²University Hospitals Leuven, Department of Gastroenterology, Leuven, Belgium, ³University of Amsterdam, Academic Medical Centre, Amsterdam, The Netherlands, ⁴Hospital Clinic of Barcelona CIBERehd, Department of Gastroenterology, Barcelona, Spain, ⁵Agaplesion Markus Hospital, Department of Medicine I, Frankfurt/Main, Germany, ⁶Department of Pharmacology and Therapeutics, Institute for Molecular and Cell Biology, Faculty of Medicine, University of Porto, and Department of Gastroenterology, Hospital de Sao Joao, Porto, Portugal, ⁷Janssen-Cilag Polska Sp. z o.o, Medical Affairs, Warsaw, Poland, ⁸Janssen-Cilag, Medical Affairs, Issy-les-Moulineaux, France, ⁹Janssen Global Services LLC, Medical Affairs, Horsham, PA, USA, ¹⁰Janssen-Cilag B.V., Medical Affairs, Breda, The Netherlands, ¹¹Janssen-Cilag Russia, Medical Affairs, Moscow, Russian Federation, ¹²Mauriziano Hospital, Gastroenterology Unit, Turin, Italy, ¹³Clinical Center ISCARE, Clinical and Research Center for Inflammatory Bowel Diseases, Prague, Czech Republic, ¹⁴Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, IBD Unit Presidio Columbus, Rome, Italy, ¹⁵Glasgow Royal Infirmary, Department of Gastroenterology, Glasgow, UK, ¹⁶University Hospital of Nancy University of Lorraine, INSERM Unité 954 and Department of Hepato-Gastroenterology, Houdemont, France

¹Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium, ²Department of Hospital Pharmacy, Amsterdam UMC, Amsterdam, The Netherlands, ³Hepato-gastroenterology and Digestive Oncology, Haut-Lévêque Hospital- Bordeaux UMC, Bordeaux, France, ⁴Department of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam, The Netherlands, ⁵Department of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium

¹Department of Radiology, Hospital Clínic de Barcelona, Barcelona, Spain, ²Icahn School of Medicine at Mount Sinai, Department of Gastroenterology, New York, USA, ³Division of Gastroenterology-, University of British Columbia, Vancouver, Canada, ⁴Takeda, Global Medical Affairs, Zurich, Switzerland, ⁵Clinical Development and Clinical Translation, Takeda, Cambridge, USA, ⁶Takeda, Department of Imaging, Cambridge, USA, ⁷Takeda, Statistical and Quantitative Sciences, Zurich, Switzerland, ⁸Department of Gastrointestinal Immunopathology, Humanitas University, Milan, Italy

¹Takeda, Quantitative Clinical Pharmacology, Cambridge, USA, ²Takeda, Clinical Pharmacology, Deerfield, USA, ³Metrum Research Group, Tariffville, USA, ⁴Takeda, Statistical and Quantitative Sciences, R&D, Cambridge, USA, ⁵Takeda, Research and Development, Global Clinical Sciences, Cambridge, USA, ⁶Western University, Robarts Clinical Trials, London, Ontario, Canada, ⁷Division of Gastroenterology, University of California San Diego, La Jolla, USA, ⁸Department of Gastroenterology, University Hospitals Leuven, Leuven, Belgium, ⁹Department of Gastroenterology, Amsterdam University Medical Centers, Amsterdam, The Netherlands

¹Department of Translational Research Centre for GastroIntestinal Disorders TARGID, KU Leuven, Leuven, Belgium, ²Immunology Clinical Development, AbbVie Inc., Worcester, USA, ³Department of Chronic Diseases, Metabolism and Ageing, CHROMETA, KU Leuven, Leuven, Belgium, ⁴Discovery and Exploratory Statistics, AbbVie Inc., Worcester, USA, ⁵Health Economics and Outcomes Research HEOR, AbbVie Inc., Worcester, USA, ⁶Global Pharmaceutical Research and Development, AbbVie Inc., North Chicago, USA, ⁷Department of Gastroenterology, Instituto Clinico Humanitas, Milan, Italy

¹Severance Hospital, Internal Medicine, Seoul, Korea Republic of, ²Yonsei Institute of Pharmaceutical Sciences, Yonsei University, College of Pharmacy, Incheon, Korea Republic of

¹Department of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, USA, ²Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, USA, ³Department of Gastroenterology, Takeda Pharmaceuticals, Deerfield, USA, ⁴Lilly Biomedicines, Eli Lilly & Company, Indianapolis, USA, ⁵Department of Gastroenterology, Mount Sinai, New York, USA

¹Division of Gastroenterology and Hepatology, Maastricht Universitair Medisch Centrum+, Pacmed, Maastricht, The Netherlands, ²Division of Gastroenterology and Hepatology, Maastricht Universitair Medisch Centrum+, Maastricht, The Netherlands, ³Haga Ziekenhuis, Department of Gastroenterology, Den Haag, The Netherlands, ⁴Department of Gastroenterology, Leiden University Medical Center, Leiden, The Netherlands, ⁵Department of Gastroenterology, Zuyderland Medical Centre, Sittard, The Netherlands, ⁶Department of Gastroenterology, St. Antonius Ziekenhuis, Nieuwegein, The Netherlands, ⁷Stichting mijnIBDcoach, Board, Mijdrecht, The Netherlands, ⁸Department of Gastroenterology, Universitair Medisch Centrum Groningen, Groningen, The Netherlands, ⁹Department of Health Care, Pacmed, Amsterdam, The Netherlands, ¹⁰Information Systems, Faculty of Industrial Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands, ¹¹Department of Internal Medicine, Division of Gastroenterology-Hepatology, University Maastricht, Maastricht, The Netherlands, ¹²Department of Quantitative Economics, School of Business and Economics, Maastricht University, Maastricht, The Netherlands, ¹³Department of Data Analytics and Digitalisation, Maastricht University, Maastricht, The Netherlands

¹Department of Gastroenterology, Oslo University Hospital, Oslo, Norway, ²Department of Gastroenterology and Hepatology, Danderyds Hospital, Stockholm, Sweden, ³Department of Gastrounit- Medical Division, Hvidovre University Hospital, Hvidovre, Denmark, ⁴Department of Medical Gastroenterology, Herlev Hospital, Herlev, Denmark, ⁵Department of Medicine, Hospital South West Denmark, Department of Regional Health Research, University of Southern Denmark, Odense, Denmark, ⁶Department of Gastroenterology, University of Turku, Turku, Finland, ⁷Takeda AS, Medical Affairs, Asker, Norway, ⁸Takeda Oy, Medical Affairs, Helsinki, Finland, ⁹Department of Medical Affairs, Takeda Pharma AB, Stockholm, Sweden, ¹⁰Department of Medical Affairs, Taastrup, Denmark, ¹¹Department of Health Management and Health Economics, Institute of Health and Society, University of Oslo, Oslo, Norway

¹Department of Gastroenterology- IBD Unit, University Hospital Santiago De Compostela CHUS, Santiago De Compostela, Spain, ²Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gatroenterology, Hospital Universitario de Alicante, Alicante, Spain, ³Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gastroenterology, Hospital Universitari Mútua Terrassa, Terrasa, Spain, ⁴Centro de de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD-, Gastroenterology, Hospital Universitario La Fe, Valencia, Spain, ⁵Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gastroenterology, Corporació Sanitaria Universitària Parc Taulí, Sabadell, Spain, ⁶Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gastroenterology, Hospital Universitario de La Princesa and Instituto de Investigación Sanitaria Princesa IIS-IP, Madrid, Spain, ⁷Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gastroenterology, Germans Trias i Pujol, Badalona, Spain, ⁸Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Hospital Clinic, Gastroenterology, Barcelona, Spain

Department of General Surgery, Jinling Hospital, Nanjing, China

¹Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, USA, ²Department of Medicine, University Hospital Schleswig-Holstein, Kiel, Germany, ³Department of Gastrointestinal Immunopathology, Humanitas University, Milan, Italy, ⁴Department of Gastroenterology, Nancy University Hospital, Nancy, France, ⁵Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, USA, ⁶Global Outcomes Research and Epidemiology, Takeda, Cambridge, USA, ⁷Statistics and Quantitative Sciences, Takeda, Cambridge, USA, ⁸Clinical Science, Takeda, Cambridge, USA

¹Department of Gastroenterology, University of North Carolina, Chapel Hill, USA, ²Department of Gastroenterology, Atrium Health, Charlotte, USA, ³Department of Gastroenterology, Cleveland Clinic, Cleveland, USA, ⁴Department of Gastroenterology, University of Wisconsin, Madison, USA, ⁵Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai Medical Center, New York, USA, ⁶Department of Gastroenterology, University of Chicago, Chicago, USA, ⁷Department of Pediatric Gastroenterology and Nutrition, Mount Sinai School of Medicine, New York, USA, ⁸Department of Gastroenterology, Dartmouth Hitchcock, Lebanon, USA, ⁹Department of Statistics, TARGET PharmaSolutions, Durham, USA, ¹⁰Scientific and Medical Affairs, TARGET PharmaSolutions, Durham, USA

¹University of Helsinki and Helsinki University Hospital, Helsinki, Finland, ²Tampere University Hospital, Tampere, Finland, ³ESiOR Oy, Kuopio, Finland, ⁴Kanta-Häme Central Hospital, Hämeenlinna, Finland, ⁵North Karelia Central Hospital, Joensuu, Finland, ⁶South Karelia Central Hospital, Lappeenranta, Finland, ⁷Lapland Central Hospital, Rovaniemi, Finland, ⁸Oulu University Hospital, Oulu, Finland, ⁹Central Finland Central Hospital, Jyväskylä, Finland, ¹⁰Satakunta Central Hospital, Pori, Finland, ¹¹Vaasa Central Hospital, Vaasa, Finland, ¹²Turku University Hospital, Turku, Finland, ¹³Kuopio University Hospital, Kuopio, Finland, ¹⁴Kainuu Central Hospital, Kajaani, Finland, ¹⁵Päijät-Häme Central Hospital, Lahti, Finland, ¹⁶Turku University Hospital Salo Hospital, Salo, Finland, ¹⁷Central Ostrobothnia Central Hospital, Kokkola, Finland, ¹⁸Janssen Cilag, Medical Affairs, Solna, Sweden, ¹⁹Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark, ²⁰Janssen Cilag Limited, Emea Hemar, High Wycombe, UK, ²¹Medical Affairs, Janssen Cilag Oy, Espoo, Finland