P597: Cycling Anti-TNF Therapy in Inflammatory Bowel Disease: Effectiveness and Durability of Switching from adalimumab to infliximabECCO'21 VirtualYear: 2021
Authors: Steinberg, J.(1);Andersen, M.(1);Krugliak Cleveland, N.(1);Traboulsi, C.(1);Rodriguez, T.(1);Cohen, R.(1);Dalal, S.(1);Micic, D.(1);Pekow, J.(1);Atsushi, S.(1);Rubin, D.(1);
(1)University of Chicago Medicine, Inflammatory Bowel Disease Center, Chicago, United States
P599: Perspectives on disease- and treatment-related issues encountered by patients with Inflammatory Bowel Disease: a qualitative concept mapping studyECCO'21 VirtualYear: 2021
Authors: Risager Christensen, K.(1);Steenholdt, C.(1);Skougaard, M.(2);Ainsworth, M.A.(3);Brynskov, J.(1);Buhl, S.(1);Kristensen, L.E.(2);Schjødt Jørgensen, T.(2);
(1)Gentofte and Herlev Hospital, Gastroenterology, Herlev, Denmark;(2)The Parker Institute- Copenhagen University Hospital, Rheumatology, Copenhagen, Denmark;(3)Odense University Hospital, Gastroenterology, Odense, Denmark
P600: Real-world clinical characteristics and therapeutic strategies in patients with moderate-to-severe Inflammatory Bowel Disease in Argentina: Data from the RISE AR studyECCO'21 VirtualYear: 2021
Authors: Lasa, J.S.(1,2);Sambuelli, A.(3);Zubiaurre, I.(2);Correa, G.J.(4);Lubrano, P.(5);Balderramo, D.C.(6,7);Ruffinengo, O.(8);Brion, L.(9);Leonardi, D.B.(9);El-Hakeh, J.(9);Guimaraens, P.N.(9);Olivera Sendra, P.(1,5);
(1)Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno CEMIC, Gastroenterology Section- Department of Internal Medicine, Buenos Aires, Argentina;(2)Hospital Británico de Buenos Aires, Gastroenterology Department, Buenos Aires, Argentina;(3)Hospital de Gastroenterología Dr. Bonorino Udaondo, Inflammatory Diseases Section, Buenos Aires, Argentina;(4)Hospital Interzonal General de Agudos General José de San Martin, Gastroenterology Department, La Plata, Argentina;(5)Sanatorio Mater Dei, Gastroenterology Department, Buenos Aires, Argentina;(6)Hospital Privado Centro Médico de Córdoba, Gastroenterology Department, Córdoba, Argentina;(7)Instituto Universitario de Ciencias Biomédicas de Córdoba, Internal Medicine Department, Córdoba, Argentina;(8)Hospital Provincial del Centenario, Gastroenterology and Hepatology Service, Rosario, Argentina;(9)Takeda Pharma S.A., Medical Affairs, Buenos Aires, Argentina
P602: Vedolizumab subcutaneous influencing disease course in Constant-care app solutionECCO'21 VirtualYear: 2021
Authors: Nørgaard, J.(1);Malte, R.(1);Charlotte, P.L.(1);Mette, B.(1);Eva, F.(1);Petra, W.(1);Dorit, A.(1);Lotte, S.(1);Johan, B.(1);Pia, M.(1);
(1)Northern Zealand Hospital, Gastroenterological department, Frederikssund, Denmark
P603: Patient characteristics and adverse effects in biologic treatment of Crohn’s Disease and Ulcerative Colitis: A nationwide Danish cohort study years 2015-2018.ECCO'21 VirtualYear: 2021
Authors: Bjørn Jensen, C.(1);Jarlov Jensen, K.(1);Wennerström, C.(2);Sommer, K.J.(3);Burisch, J.(4);Petersen, J.(1);
(1)Frederiksberg Hospital- Frederiksberg- Denmark., Copenhagen Phase IV Unit- Center for Clinical Research and Prevention-, Frederiksberg, Denmark;(2)Janssen Cilag AB, Nordic Medical Operations, Solna, Sweden;(3)Janssen-Cilag A/S, Medical Affairs, Birkerød, Denmark;(4)Hvidovre Hospital, Gastrounit- Medical Division-, Hvidovre, Denmark
P604: Evaluation of management heterogeneity and complications of Crohn’s disease in Catalonia. A population quality care studyECCO'21 VirtualYear: 2021
Authors: Brunet, E.(1);Melcarne, L.(1);Llovet, L.(1);Vela, E.(2);Cleries, M.(2);Pontes, C.(3,4);Garcia-Iglesias, P.(1,5);Albert, V.(1,5,6);Calvet, X.(1,5,6);
(1)Hospital Parc Taulí, Aparell digestiu, Sabadell, Spain;(2)Generalitat de Catalunya, Unitat d’Informació i Coneixement. Servei Català de la Salut, Barcelona, Spain;(3)Generalitat de Catalunya, Àrea del Medicament. Servei Català de la Salut, Barcelona, Spain;(4)Universitat Autònoma de Barcelona., Departament de Farmacologia- de terapéutica i de Toxicologia., Bellaterra, Spain;(5)Instituto de Salud Carlos III., CIBERehd, Madrid, Spain;(6)Universitat Autònoma de Barcelona, Departament de Medicina, Barcelona, Spain
P605: Development and validation of an objective disability index for Inflammatory Bowel Disease patients (ODIBD)ECCO'21 VirtualYear: 2021
Authors: Melcarne, L.(1);Vergara Gómez, M.(1);Villoria Ferrer, A.(1);Brunet Mas, E.(1);Garcìa Iglesias, P.(1);Llovet Soto, L.(1);Dosal Galguera, A.(1);Monllor Nunell, T.(1);Alforcea Alcaraz, S.(1);Calvet Calvo, X.(1);
(1)Hospital Universitari Parc Taulì, Digestive Disease, Sabadell Barcelona, Spain
P606: Adherence to endoscopic surveillance guidelines for advanced lesions and colorectal cancer in Inflammatory Bowel Disease in Spain: a collaborative study of AEG and GETECCU.ECCO'21 VirtualYear: 2021
Authors: Ballester Ferré, M.P.(1);Mesonero, F.(2);Flórez-Diez, P.(3);Gómez, C.(1);Fuentes-Valenzuela, E.(4);Martín, N.(5);Senosiain, C.(2);Vela, M.(6);Fernández-Clotet, A.(7);Pérez, P.(8);Rubín de Célix, C.(9);Calviño-Suárez, C.(10);Ferreiro-Iglesias, R.(10);Hermida, B.(11);Muñoz, R.(12);González-Vivo, M.(13);Brunet, E.(14); Jiménez, N.(15);Botella, B.(16); Yebra, J.(17);Suárez, C.(18);Bouhmidi, A.(19);Jurado, R.M.(19);López, A.(20);Algarra, Á.(20);Besó, P.(20);Ponferrada, Á.(21);Plaza, R.(21);Dueñas, C.(22);Benítez, J.M.(23);Soto, P.(23);Castillo, E.(24); Iyo, E.(25);Carbonell-Asíns, J.A.(26);Beltran, B.(27);Mínguez, M.(1);
(1)Hospital Clínico Universitario de Valencia, Digestive Disease Department, Valencia, Spain;(2)Hospital Universitario Ramón y Cajal, Digestive Disease Department, Madrid, Spain;(3)Hospital Universitario Central de Asturias, Digestive Disease Department, Oviedo, Spain;(4)Hospital Universitario Rio Hortega, Digestive Disease Department, Valladolid, Spain;(5)Hospital de Galdakao, Digestive Disease Department, Galdakao, Spain;(6)Hospital Universitario Nuestra Señora de Candelaria, Digestive Disease Department, Sant Cruz de Tenerife, Spain;(7)Hospital Clínic de Barcelona, Digestive Disease Department, Barcelona, Spain;(8)Hospital Provincial de Pontevedra, Digestive Disease Department, Pontevedra, Spain;(9)Hospital de La Princesa, Digestive Disease Department, Madrid, Spain;(10)Hospital Clínico Universitario de Santiago, Digestive Disease Department, Santiago de Compostela, Spain;(11)Hospital Universitario de Cabueñes, Digestive Disease Department, Gijón, Spain;(12)Hospital General de Alicante, Digestive Disease Department, Alicante, Spain;(13)Hospital del Mar, Gastroenterology Department, Barcelona, Spain;(14)Hospital Parc Taulí, Digestive Disease Department, Sabadell, Spain;(15)Hospital General Universitario de Elche, Digestive Disease Department, Elche, Spain;(16)Hospital Universitario Infanta Cristina, Digestive Disease Department, Madrid, Spain;(17)Hospital Universitario de Móstoles, Digestive Disease Department, Móstoles, Spain;(18)Hospital La Paz, Digestive Disease Department, Madrid, Spain;(19)Hospital Santa Bárbara Puertollano, Digestive Disease Department, Puertollano, Spain;(20)Hospital Doctor Peset, Digestive Disease Department, Valencia, Spain;(21)Hospital Universitario Infanta Leonor, Digestive Disease Department, Madrid, Spain;(22)Hospital Universitario de Cáceres, Digestive Disease Department, Cáceres, Spain;(23)Hospital Universitario Reina Sofía de Córdoba, Digestive Disease Department, Córdoba, Spain;(24)Hospital Sant Jaume de Calella, Digestive Disease Department, Calella, Spain;(25)Hospital Comarcal de Inca, Digestive Disease Department, Inca, Spain;(26)INCLIVA Biomedical Research Institute, Bioinformatics and biostatistics Unit, Valencia, Spain;(27)Hospital Universitario y Politécnico La Fe, Digestive Disease Department, Valencia, Spain; On behalf of Young Group of AEG and GETECCU
P607: The Faroese IBD Study: Update on incidence from 2015-2020 and prevalence from 1960-2020ECCO'21 VirtualYear: 2021
Authors: Nielsen, K.R.(1);Midjord, J.(1);Hammer, T.(2);Lophaven, S.(3);Burisch, J.(4);
(1)National Hospital of the Faroe Islands, Department of Medicine, Tórshavn, Faroe Islands;(2)The Faroese Hospital System, Department of Occupational Medicine and Public Health, Tórshavn, Faroe Islands;(3)Omicron Aps, Omicron Aps, Roskilde, Denmark;(4)Hvidovre University Hospital, Gastrounit- Medical section, Hvidovre, Denmark; The Faroese IBD Study
P608: Inflammatory Bowel Disease (IBD) and immunosuppression do not worsen the prognosis of COVID-19. Results from the ENEIDA Project of GETECCUECCO'21 VirtualYear: 2021
Authors: Zabana Abdo, Y.(1,2);Marín-Jiménez, I.(3);Rodríguez-Lago, I.(4);Ramírez Esteso, F.(5);Meijilde, S.(6);Ramos, L.(7);Gomollón, F.(2,8);Muñoz, F.(9);Suris, G.(10);Ortiz de Zárate, J.(11);Huguet, J.M.(12);Llaó, J.(13);García-Sepulcre, M.(14);Sierra, M.(15);Durà, M.(16);Estrecha, S.(17);Fuentes Coronel, A.(18);Hinojosa, E.(19);Olivan, L.(20);Iglesias, E.(21);Gutiérrez, A.(2,22);Varela, P.(23);Rull, N.(24);Gilabert, P.(25);Hernández-Camba, A.(26);Brotons, A.(27);Ginard, D.(28);Sesé, E.(29);Carpio, D.(30);Aceituno, M.(1,2);Cabriada, J.L.(4);González-Lama, Y.(31);Jiménez, L.(32);Chaparro, M.(2,33);López-San Román, A.(34);Alba, C.(35);Plaza-Santos, R.(36);Piqueras, M.(37);Domènech, E.(2,38);Esteve, M.(1,2);
(1)Hospital Universitari Mútua de Terrassa, Gastroenterology Department- Inflammatory Bowel Disease Unit, Terrassa, Spain;(2)Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREehd, CIBERehd, Madrid, Spain;(3)Hospital Gregorio Marañón, Gastroenterology Department, Madrid, Spain;(4)Hospital de Galdakao, Gastroenterology Department, Bilbao, Spain;(5)Hospital General Universitario de Ciudad Real, Gastroenterology Department, Ciudad Real, Spain;(6)Hospital Universitario de Cruces, Gastroenterology Department, Baracaldo, Spain;(7)Hospital Universitario de Canarias, Gastroenterology Department, Gran Canaria, Spain;(8)Hospital Clínico Universitario 'Lozano Blesa' e IIS Aragón, Gastroenterology Department, Zaragoza, Spain;(9)Hospital Universitario de Salamanca, Gastroenterology Department, Salamanca, Spain;(10)Hospital Universitari de Bellvitge, Gastroenterology Department, L'Hospitalet de Llobregat, Spain;(11)Hospital Universitario de Basurto, Gastroenterology Department, Basurto, Spain;(12)Consorcio Hospital General Universitario de Valencia, Gastroenterology Department, Valencia, Spain;(13)Althaia Xarxa Assistencial Universitària de Manresa, Gastroenterology Department, Manresa, Spain;(14)Hospital Universitario de Elche, Hospital Universitario de Elche, Elche, Spain;(15)Complejo Asistencial Universitario de León, Gastroenterology Department, León, Spain;(16)Hospital Clínico de Valladolid, Gastroenterology Department, Valladolid, Spain;(17)Hospital Universitario Álaba HUA, Gastroenterology Department, Álaba, Spain;(18)Hospital Virgen de la Concha, Gastroenterology Department, Zamora, Spain;(19)Hospital de Manises, Gastroenterology Department, Manises, Spain;(20)Hospital Universitario San Jorge, Gastroenterology Department, Huesca, Spain;(21)Hospital Universitario Reina Sofía de Córdoba e Instituto Maimónides de Investigación Biomédica de Córdoba IMIBIC- Córdoba, Gastroenterology Department, Córdoba, Spain;(22)Hospital General Universitario de Alicante, Gastroenterology, Alicante, Spain;(23)Hospital Universitario de Cabueñes, Gastroenterology Department, Gijón, Spain;(24)Hospital Universitario Son Llàtzer, Gastroenterology Department, Mallorca, Spain;(25)Hospital de Viladecans, Gastroenterology Department, Viladecans, Spain;(26)Hospital Universitario Nuestra Señora de Candelaria, Gastroenterology Department, Santa Cruz de Tenerife, Spain;(27)Hospital Vega Baja de Orihuela, Gastroenterology Department, Orihuela, Spain;(28)Hospital Universitario Son Espases, Gastroenterology Department, Palma de Mallorca, Spain;(29)Hospital Universitari Arnau de Vilanova de Lleida, Gastroenterology Department, Lleida, Spain;(30)Complexo Hospitalario de Pontevedra, Gastroenterology Department, Pontevedra, Spain;(31)Hospital Universitario Puerta de Hierro Majadahonda, Gastroenterology Department, Majadahonda, Spain;(32)Hospital Universitario de Fuenlabrada e Instituto de Investigación Hospital Universitario La Paz IdiPaz, Gastroenterology Department, Madrid, Spain;(33)Hospital Universitario de La Princesa and Instituto de Investigación Sanitaria Princesa IIS-IP, Gastroenterology Department, Madrid, Spain;(34)Hospital Universitario Ramón y Cajal, Gastroenterology Department, Madrid, Spain;(35)Hospital Clínico San Carlos and Instituto de Investigación del Hospital Clínico San Carlos [IdISSC], Gastroenterology Department, Madrid, Spain;(36)Hospital Universitario Infanta Leonor, Gastroenterology Department, Madrid, Spain;(37)Consorci Sanitari de Terrassa, Gastroenterology Department, Terrassa, Spain;(38)Hospital Universitari Germans Trias i Pujol, Gastroenterology Deparment, Badalona, Spain; COVID-19-EII Consortium of the ENEIDA project of GETECCU
P609: Impact of accessibility of medical care and socioeconomic class on outcomes of IBD – a nationwide population studyECCO'21 VirtualYear: 2021
Authors: Ledder, O.(1);Harel, S.(1);Orlanski-Meyer, E.(1);Yogev, D.(1);Loewenberg Weisband, Y.(2);Greenfeld, S.(3);Kariv, R.(3);Lederman, N.(4);Matz, E.(5);Schwartz, D.(6);Focht, G.(1);Dotan, I.(7);Turner, D.(1);
(1)Shaare Zedek Medical Center, Department of Pediatric Gastroenterology and Nutrition, Jerusalem, Israel;(2)Clalit Health Services, Clalit Research Institute, Tel Aviv, Israel;(3)Maccabi Healthcare Services, Maccabi Healthcare Services, Tel Aviv, Israel;(4)Meuhedet Health Services, Meuhedet Health Services, Tel Aviv, Israel;(5)Leumit Health Services, Leumit Health Services, Tel Aviv, Israel;(6)Soroka Medical Center, Department of Gastroenterology and Hepatology-, Beer Sheva, Israel;(7)Rabin Medical Center, Division of Gastroenterology, Petah Tikva, Israel
P610: Fear of COVID-19 among persons with Inflammatory Bowel Disease according to employment status, educational background and residential setting, as compared to persons with other gastrointestinal conditionsECCO'21 VirtualYear: 2021
Authors: Lo, B.Z.S.(1);Mokrowiecka, A.(2);Mikocka-Walus, A.(3);Bernstein, C.N.(4,5);Trindade, I.A.(6);Burisch, J.(1);Barreiro-de Acosta, M.(7);Ferreira, N.(8);Gearry, R.B.(9);Knowles, S.R.(10);
(1)Copenhagen University Hospital Hvidovre, The Gastrounit, Hvidovre, Denmark;(2)Medical University of Lodz, Dept of Digestive Tract Diseases, Lodz, Poland;(3)University Geelong, School of Psychology- Deakin, Melbourne, Australia;(4)Faculty of Health Sciences University of Manitoba, Department of Medicine Rady, Winnipeg, Canada;(5)University of Manitoba, IBD Clinical and Research Centre, Winnipeg, Canada;(6)University of Coimbra, Cognitive and Behavioral Centre for Research and Intervention, Coimbra, Portugal;(7)University Hospital of Santiago de Compostela, IBD Unit, Santiago de Compostela, Spain;(8)University of Nicosia, Department of Social Sciences, Nicosia, Cyprus;(9)University of Otago, Department of Medicine, Christchurch, New Zealand;(10)Swinburne University of Technology, Department of Psychology, Melbourne, Australia
P611: Incidence, clinical presentation, and severity of SARS-CoV-2 infection in IBD patients in the second and the third wave of infectionECCO'21 VirtualYear: 2021
Authors: Algaba Garcia, A.(1);Guerra, I.(1);Castro, S.(2);Jiménez, L.(1);Garza, D.(1);Aller, M.D.M.(1);Granja, A.(1);Guardiola, A.(1);Bellart, M.(2);Pizarro, N.(2);Bermejo, F.(1);
(1)Hospital Universitario de Fuenlabrada and Instituto de Investigación Sanitaria Hospital Universitario La Paz IdiPAZ, Gastroenterology, Madrid, Spain;(2)Hospital Universitario de Fuenlabrada, Gastroenterology, Madrid, Spain
P612: Lower incidence of COVID-19 in patients with Inflammatory Bowel Diseases treated with non-gut-selective biologic therapy: an observational multicentre study.ECCO'21 VirtualYear: 2021
Authors: Ferretti, F.(1);Monico, M.C.(1);Carvalhas Gabrielli, A.M.(1);Carmagnola, S.(1);Bezzio, C.(2);Saibeni, S.(2);Bosani, M.(3);Caprioli, F.(4);Mazza, S.(4);Casini, V.(5);Cortelezzi, C.(6);Parravicini, M.(6);Cassinotti, A.(6);Cosimo, P.(7);Indriolo, A.(7);Di Sabatino, A.(8);Lenti, M.V.(8);Pastorelli, L.(9);Conforti, F.(9);Ricci, C.(10);Sarzi-Puttini, P.(11);Vecchi, M.(4);Maconi, G.(1);Ardizzone, S.(11);
(1)ASST Fatebenefratelli-Sacco- Ospedale L. Sacco, Department of Biochemical and Clinical Sciences, Milan, Italy;(2)ASST Rhodense- Rho Hospital- Rho- Italy, Gastroenterology Unit, Rho, Italy;(3)General Hospital Legnano- Legnano- Italy., Gastroenterology Unit, Legnano, Italy;(4)Fondazione IRCCS Ca' Granda Ospedale Maggiore di Milano Policlinico- Milano- Lombardia- Italy., Department of Pathophysiology and Transplantation- University of Milan- Milano- Lombardia- Italy., Milan, Italy;(5)ASST Bergamo Est- Seriate- Lombardia- Italy, UOC Gastroenterology and Digestive Endoscopy, Seriate, Italy;(6)ASST Sette Laghi- Gastroenterology and GI Endoscopy Unit- Ospedale di Circolo e Fondazione Macchi- Varese- Italy, ASST Sette Laghi- Gastroenterology and GI Endoscopy Unit- Ospedale di Circolo e Fondazione Macchi- Varese- Italy, Varese, Italy;(7)Papa Giovanni XXIII Hospital- Bergamo- Italy., Gastroenterology and Endoscopy Unit, Bergamo, Italy;(8)IRCCS Ospedale San Matteo, Department of Internal Medicine- Università degli Studi di Pavia- Pavia- Lombardia- Italy, Pavia, Italy;(9)IRCCS Policlinico San Donato- San Donato Milanese- Lombardia- Italy, Gastroenterology Unit, San Donato Milanese, Italy;(10)ASST Spedali Civili di Brescia- Brescia- Lombardia- Italy, Gastroenterology Unit, Brescia, Italy;(11)ASST-Fatebenefratelli L. Sacco University Hospital- University of Milan- Italy, Rheumatology Unit, Milan, Italy
P614: A strategy to solve complexity of physician diagnosis using a mixture of Patient Reports and Provider Reports: A Case Study of Crohn’s Disease PhenotypesECCO'21 VirtualYear: 2021
Authors: Zhang, L.(1);Fan, Y.(2);Thompson, J.(3);Bohn, R.(4);Negar, O.(4);Brodovicz, K.(2);Parakkal, D.(5);
(1)Boehringer Ingelheim Pharmaceuticals Inc., Real World Evidence Analytics Center of Excellence, Ridgefield, United States;(2)Boehringer Ingelheim Pharmaceuticals Inc., Global Epidemiology, Ridgefield, United States;(3)Boehringer Ingelheim Pharmaceuticals Inc., TA Inflammation Medicine, Ridgefield, United States;(4)Bohn Epidemiology, Consulting Services, Boston, United States;(5)Washington University School of Medicine, Institute of Clinical and Translational Sciences, Saint Louis, United States
P615: Does smoking really influence the development and the outcomes of Inflammatory Bowel Disease in Asian population? Results from the Taiwanese patientsECCO'21 VirtualYear: 2021
Authors: Chen, B.C.(1);Weng, M.T.(2);Chang, C.H.(3);Huang, L.Y.(4);Wei, S.C.(2);
(1)National Taiwan University, School of Medicine- College of Medicine, Taipei, Taiwan- Province Of China;(2)National Taiwan University Hospital, Department of Internal Medicine, Taipei, Taiwan- Province Of China;(3)National Taiwan University Hospital, Department of Medical Research, Taipei, Taiwan- Province Of China;(4)National Taiwan University Hospital, Clinical Trial Center, Taipei, Taiwan- Province Of China
P616: Sustainability of thiopurines monotherapy in ulcerative colitis: a nationwide analysis from the epi-IIRN cohortECCO'21 VirtualYear: 2021
Authors: Atia, O.(1); Friss, C.(1); Mendelovici, A.(1); Shteyer, E.(1); Orlanski-Meyer, E.(1); Ledderman, N.(2); Greenfeld, S.(3); Kariv, R.(3); Loewenberg Weisband, Y.(4);Gabay, H.(5); Nevo, D.(6); Matz, E.(7); Dotan, I.(8);Turner, D.(1);
(1)Shaare Zedek Medical Center- The Hebrew University of Jerusalem- Israel., Juliet Keidan Institute of Pediatric Gastroenterology Hepatology and Nutrition, Jerusalem, Israel;(2)Meuhedet Health Services, Meuhedet Health Services, Tel-Aviv, Israel;(3)Maccabi Health Services, The Sackler Faculty of Medicine- Tel Aviv University- Israel., Tel-Aviv, Israel;(4). Clalit Health Services, Clalit Research Institute, Tel-Aviv, Israel;(5)Clalit Health Services, Clalit Research Institute, Tel-Aviv, Israel;(6)Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv, Israel;(7)Leumit Health Services, Leumit Health Services, Tel-Aviv, Israel;(8)Division of Gastroenterology- Rabin Medical Center, The Sackler Faculty of Medicine- Tel Aviv University- Israel., Petah Tikva, Israel
