P357: Long-term outcomes of biologic therapy in Crohn’s disease complicated with internal fistulizing disease: BIOSCOPE study from GETECCUECCO'21 VirtualYear: 2021
Authors: Rodríguez-Lago, I.(1);Fernández-Clotet, A.(2,3);Mesonero, F.(4);García-Alonso, F.J.(5);Casanova, M.J.(6);Fernández-de la Varga, M.(7);Cañete, F.(8);de Castro, L.(9);Gutiérrez, A.(10);Sicilia, B.(11);Cano, V.(12);Merino, O.(13);Riestra, S.(14);González-Partida, I.(15);Surís, G.(16);Torrealba, L.(17);Ferreiro-Iglesias, R.(18);Castro, B.(19);Márquez, L.(20);Sobrino, A.(21);Elorza, A.(1);Calvet, X.(22);Varela, P.(23);Betoré, E.(24);Bujanda, L.(25);Lario, L.(26);Manceñido, N.(27);García-Sepulcre, M.(28);Iglesias, E.(29);Rodríguez, C.(30);Piqueras, M.(31);Ferrer Rosique, J.Á.(32);Lucendo, A.(33);Benítez, O.(34);García, M.(35);Olivares, D.(36);González-Muñoza, C.(37);Cabriada, J.L.(1);Domènech, E.(8);Barreiro-de Acosta, M.(18);
(1)Hospital de Galdakao, Gastroenterology, Galdakao, Spain;(2)Hospital Clinic, Gastroenterology, Barcelona, Spain;(3)Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBERehd, Gastroenterology, Madrid, Spain;(4)Hospital Universitario Ramón y Cajal, Gastroenterology, Madrid, Spain;(5)Hospital Universitario Río Hortega, Gastroenterology, Valladolid, Spain;(6)Hospital Universitario de La Princesa- Instituto de Investigación Sanitaria Princesa IIS-IP- Universidad Autónoma de Madrid UAM, Gastroenterology, Madrid, Spain;(7)Hospital Universitari i Politecnic la Fe, Gastroenterology, Valencia, Spain;(8)Hospital Universitari German Trias i Pujol, Gastroenterology, Badalona, Spain;(9)Hospital Álvaro Cunqueiro, Gastroenterology, Vigo, Spain;(10)Hospital General Universitario de Alicante, Gastroenterology, Alicante, Spain;(11)Hospital Universitario de Burgos, Gastroenterology, Burgos, Spain;(12)Hospital Universitario de León, Gastroenterology, León, Spain;(13)Hospital Universitario de Cruces, Hospital Universitario de Cruces, Barakaldo, Spain;(14)Hospital Universitario Central de Asturias, Gastroenterology, Oviedo, Spain;(15)Hospital Universitario Puerta de Hierro, Gastroenterology, Madrid, Spain;(16)Hospital Universitari de Bellvitge, Gastroenterology, Barcelona, Spain;(17)Hospital Universitari Dr Josep Trueta, Gastroenterology, Girona, Spain;(18)Hospital Clínico Universitario de Santiago de Compostela, Gastroenterology, Santiago de Compostela, Spain;(19)Hospital Universitario Marqués de Valdecilla, Gastroenterology, Santander, Spain;(20)Hospital de Mar, Gastroenterology, Barcelona, Spain;(21)Hospital General Universitario de Ciudad Real, Gastroenterology, Ciudad Real, Spain;(22)Corporació Sanitària Universitària Parc Taulí, Gastroenterology, Sabadell, Spain;(23)Hospital de Cabueñes, Gastroenterology, Gijón, Spain;(24)Hospital Universitario Miguel Servet, Hospital Universitario Miguel Servet, Zaragoza, Spain;(25)Hospital Universitario Donostia, Gastroenterology, Donostia, Spain;(26)Hospital Clínico Universitario Lozano Blesa, Gastroenterology, Zaragoza, Spain;(27)Hospital Universitario Infanta Sofía, Gastroenterology, Madrid, Spain;(28)Hospital General Universitario de Elche, Gastroenterology, Elche, Spain;(29)Hospital Universitario Reina Sofía- IMIBIC, Gastroenterology, Córdoba, Spain;(30)Complejo Hospitalario de Navarra, Gastroenterology, Pamplona, Spain;(31)Consorci Sanitari de Terrassa, Gastroenterology, Terrassa, Spain;(32)Hospital Universitario Fundación Alcorcón, Gastroenterology, Alcorcón, Spain;(33)Hospital General de Tomelloso, Gastroenterology, Tomelloso, Spain;(34)Hospital Universitari Mútua Terrassa, Gastroenterology, Terrassa, Spain;(35)Hospital General San Jorge, Hospital General San Jorge, Huesca, Spain;(36)Hospital Clínico San Carlos, Gastroenterology, Madrid, Spain;(37)Hospital Santa Creu i Sant Pau, Gastroenterology, Barcelona, Spain; on behalf of the BIOSCOPE study group from the ENEIDA registry
P358: An observational, prospective cohort study to evaluate the long term safety and effectiveness of intravenous CT-P13 (biosimilar of infliximab) in patients with Crohn’s Disease or Ulcerative ColitisECCO'21 VirtualYear: 2021
Authors: Cheon, J.H.(1);Kang, H.W.(2);Lee, S.J.(3);Kim, S.H.(4);
(1)Yonsei University College of Medicine, Deparment of Internal Medicine and Institute of Gastroenterology, Seoul, Korea- Republic Of;(2)SMG-SNU Boramae Medical Center, Division of Gastroenterology and Hepatology Department of Internal Medicine, Seoul, Korea- Republic Of;(3)CELLTRION-Inc., Division of Clinical Development, Incheon, Korea- Republic Of;(4)CELLTRION-Inc., Clinical Planning, Incheon, Korea- Republic Of
P359: Influence of the nature of immunosuppressive therapy in patients with inflammatory bowel diseases on the level of immunoglobulins G after a Coronavirus InfectionECCO'21 VirtualYear: 2021
Authors: Knyazev, O.(1,2,3);Kagramanova, A.(4);Lishchinskaya, A.(1);Noskova, K.(5);Chernova, M.(6);Shkurko, T.(3);Veselov, A.(3);Kulakov, D.(1);Li, I.(1);Parfenov, A.(1);
(1)Moscow Clinical Scientific Center named after A.S. Loginov, Department of IBD, Moscow, Russian Federation;(2)State Scientific Centre of Coloproctology named after A.N. Ryzhyh, Department of IBD, Moscow, Russian Federation;(3)Research Institute of Health Organization and Medical Management, Organization of Coloproctology, Moscow, Russian Federation;(4)Moscow Clinical Scientific Center named after A.S. Loginov, Department of IBD, Moscow City, Russian Federation;(5)Moscow Clinical Scientific Center named after A.S. Loginov, Laboratory of Diagnostic, Moscow, Russian Federation;(6)Moscow Clinical Scientific Center named after A.S. Loginov, Department of Epidemiology, Moscow, Russian Federation
P360: Aggressive Inflammatory Bowel Disease is associated to Hermansky-Pudlak Syndrome: Characterization of a Puerto Rican CohortECCO'21 VirtualYear: 2021
Authors: Marrero Torres, R.(1);Coste-Sibilia, S.(1);Nieves-Jimenez, H.(1);Torres, G.(1);Rivera, E.(2);Torres, E.A.(1);
(1)University of Puerto Rico - School of Medicine, Department of Medicine - Gastroenterology, San Juan, Puerto Rico;(2) University of Puerto Rico - School of Medicine, Department of Hematology - Pediatric Hem-Onc Section, San Juan, Puerto Rico
P361: No increased postoperative risk of venous thromboembolism in patients with Ulcerative Colitis undergoing colectomy after tofacitinib exposureECCO'21 VirtualYear: 2021
Authors: De Greef, I.(1);Verstockt, B.(1);Bislenghi, G.(2);Terrasson, I.(2);Sabino, J.(1);Ferrante, M.(1);D’Hoore, A.(2);Vermeire, S.(1);
(1)KU Leuven, Gastro-enterology, Leuven, Belgium;(2)KU Leuven, Abdominal surgery, Leuven, Belgium
P362: Longitudinal antibody response to SARS-CoV-2 infection and antibody responses to COVID-19 vaccination in Inflammatory Bowel Disease patients receiving biologicsECCO'21 VirtualYear: 2021
Authors: Wong, S.Y.(1);Dixon, R.(1);Gold, S.(1);Vicky, M.(1);Helmus, D.(1);Cadwell, K.(2);Colombel, J.F.(1);
(1)Mount Sinai Hospital, Internal Medicine/Division of Gastroenterology, New York, United States;(2)NYU School of Medicine, Microbiology and Medicine/Division of Gastroenterology and Hepatology, New York, United States; CiTI Study Group
P363: Locally injected allogeneic bone marrow-derived mesenchymal stromal cells for the treatment of refractory proctitis: clinical results of a phase IIa trialECCO'21 VirtualYear: 2021
Authors: OuboterDrs., L.(1,2);Barnhoorn, M.(1);van Pel, M.(2,3);Zwaginga, J.J.(4);Hawinkels, L.(1);Maljaars, J.(1);Koning, F.(2);Verspaget, H.(1);van der Meulen - de de Jong, A.(1);
(1)Leiden University Medical Center, Department of Gastroenterology and Hepatology, Leiden, The Netherlands;(2)Leiden University Medical Center, Department of Immunology, Leiden, The Netherlands;(3)Netherlands Center for the Clinical Advancement of Stem Cell & Gene Therapies, nectsgen, Leiden, The Netherlands;(4)Leiden University Medical Center, Department of Internal Medicine, Leiden, The Netherlands
P364: Patient reported outcomes, partial MAYO score and SCCAI are equally accurate in predicting mucosal healing in UC: final results form a prospective studyECCO'21 VirtualYear: 2021
Authors: Golovics, P.(1);Gonczi, L.(2);Reinglass, J.(3);Verdon, C.(3);Pundir, S.(3);Afif, W.(3);Wild, G.(3);Bitton, A.(3);Bessissow, T.(3);Lakatos, P.L.(3);
(1)HDF Medical Centre, Division of Gastroenterology, Budapest, Hungary;(2)Semmelweis University, 1st Department of Medicine, Budapest, Hungary;(3)McGill University Health Centre, Division of Gastroenterology, Montreal, Canada
P365: Correlation between patient-reported outcomes (PROs) and patient-reported disease activity in Ulcerative Colitis (UC): Findings from the ICONIC studyECCO'21 VirtualYear: 2021
Authors: Ghosh, S.(1);Casellas, F.(2);Kligys, K.(3);Sanchez Gonzalez, Y.(4);Peyrin-Biroulet, L.(5);
(1)University of Birmingham and University Hospitals Birmingham, National Health Service Trust, Birmingham, United Kingdom;(2)Hospital Universitari Vall d’Hebron, Physiology I Digestive Pathophysiology, Barcelona, Spain;(3)AbbVie Inc., Gastroenterology, North Chicago, United States;(4)AbbVie Inc., Health Economics and Outcomes Research, North Chicago, United States;(5)University of Lorraine, Gastroenterology, Nancy, France
P366: Vedolizumab maintenance therapy reduced use of corticosteroids in patients with Crohn’s disease in the GEMINI 2 trialECCO'21 VirtualYear: 2021
Authors: D'Haens, G.(1);Candela, N.(2);Uddin, S.(3);Peterson, T.(2);Dubinsky, M.(4);Colombel, J.F.(5);
(1)Academic Medical Center, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands;(2)Takeda Pharmaceuticals USA Inc., US Medical, Lexington, United States;(3)Takeda Pharmaceuticals USA Inc., Biostatistics, Lexington, United States;(4)Icahn School of Medicine at Mount Sinai Hospital, Pediatric Gastroenterology and Hepatology, New York, United States;(5)Icahn School of Medicine at Mount Sinai Hospital, Gastroenterology, New York, United States
P367: Weight patterns in biologicals treated Inflammatory bowel disease cohortECCO'21 VirtualYear: 2021
Authors: Kaazan, P.(1,2);Tan , Z.(3);Maiyani, P.(1);Mickenbecker, M.(1);Edwards, S.(2);McIvor, C.(1);Andrews , J.M.(3);
(1)Logan Hospital, Gastroenterology and Hepatology, Brisbane, Australia;(2)The University of Adelaide, Medical sciences, Adelaide, Australia;(3)Royal Adelaide Hospital, Gastroenterology and Hepatology, Adelaide, Australia; NA
P368: Proactive Therapeutic Drug Monitoring is more effective than Conventional Management in Inducing Fecal Calprotectin remission in Inflammatory Bowel DiseaseECCO'21 VirtualYear: 2021
Authors: Pedro, J.(1);Rodrigues, I.(1);Fernandes, S.(1);Gonçalves, A.R.(1);Bernardo, S.(1);Baldaia, C.(1);Valente, A.(1);Moura Santos, P.(1);Correia, L.(1);Tato Marinho, R.(1);
(1)Centro Hospitalar Lisboa Norte, Gastrenterology, Lisboa, Portugal
P369: High prevalence of abdominal pain in Crohn's Disease patients of the TRUST study cohort- Is there a connection to inflammatory activity?ECCO'21 VirtualYear: 2021
Authors: Kugel, T.(1);Maaser, C.(2);Kucharzik, T.(3);Fischer, I.(4);Kolterer, S.(5);Hammer, L.(5);Rath, S.(5);Sturm, A.(6);
(1)Paracelsus medical university Nuernberg, Paracelsus medical university Nuernberg, Nuernberg, Germany;(2)IBD Center- Klinikum Lueneburg gGmbH, Outpatients Department of Gastroenterology, Lueneburg, Germany;(3)Klinikum Lueneburg gGmbH, Department of Gastroenterology, Lueneburg, Germany;(4)Biostatistik - Tuebingen, Biostatistik - Tuebingen, Tuebingen, Germany;(5)AbbVie Deutschland GmbH & Co. KG, Medical Department, Wiesbaden, Germany;(6)DRK hospitals Berlin Westend- academic teaching hospital of the Charité, Department of gastroenterology, Berlin, Germany
P370: Concomitant azathioprine prevents new-onset arthralgia after initiation of vedolizumab: A retrospective cohort studyECCO'21 VirtualYear: 2021
Authors: Kokkotis, G.(1);Zampeli, E.(2);Tzouvala, M.(3);Giotis, I.(3);Orfanos, P.(4);Benetou, V.(4);Stoupaki, M.(2);Gizis, M.(1);Kioulos, N.(1);Kitsou, V.(1);Leontidis, N.(3);Leonidakis, G.(2);Chatzinikolaou, M.L.(1);Perlepe, N.(1);Koutsounas, I.(1);Lagiou, P.(4);Michopoulos, S.(2);Bamias, G.(1);
(1)3rd Department of Internal Medicine- National and Kapodistrian University of Athens- Sotiria Hospital, GI Unit, Athens, Greece;(2)Alexandra General Hospital, Gastroenterology Department, Athens, Greece;(3)General Hospital Nikaias-Piraeus Agios Panteleimon- General Hospital Dytikis Attikis Agia Varvara, GI Department, Piraeus, Greece;(4)Epidemiology and Medical Statistics- School of Medicine- National and Kapodistrian University of Athens, Department of Hygiene, Athens, Greece
P371: Using digital monitoring during the COVID pandemic to streamline outpatient appointmentsECCO'21 VirtualYear: 2021
Authors: Walsh, A.J.(1);Matini, L.(1);Wilson, J.(1);Lyden, S.(1);Al-Hillawi, L.(1);Kantschuster, R.(1);Kormilitzin, A.(2);Smith, T.(1);Slater, J.(1);Payton, S.(1);White, L.(1);Woodley, H.(1);Brain, O.(1);Palmer, R.(1);Ambrose, T.(1);Satsangi, J.(1);Travis, S.P.L.(1);
(1)Oxford University Hospitals NHS Foundation Trust, Translational Gastroenterology Unit, Oxford, United Kingdom;(2)University of Oxford, Mathematical Institute, Oxford, United Kingdom
P372: Effectiveness and safety of immunosuppressants for pouch disorders: results from the RESERVO Study of GETECCUECCO'21 VirtualYear: 2021
Authors: Mesonero Gismero, F.(1);Zabana, Y.(2);Fernández-Clotet, A.(3);Leo, E.(4);Caballol, B.(3);Núñez, A.(4);García, M.J.(5);Bertoletti, F.(6);Mínguez, A.(7);Suris, G.(8);Casis, B.(9);Ferreiro-Iglesias, R.(10);Calafat, M.(11);Jiménez, I.(12);Miranda-Bautista, J.(13);Lamuela, L.J.(14);Fajardo, I.(15);Torrealba, L.(16);Nájera, R.(17);Sáiz, R.M.(18);González, I.(19);Vicuña, M.(20);García-Morales, N.(21);Gutiérrez, A.(22);López-García, A.(23);Benítez, J.M.(24);Rubín de Célix, C.(25);Tejido, C.(26);Brunet, E.(27);Hernández, A.(28);Suárez, C.(29);Piqueras, M.(30);Castaño, A.(31);Ramos, L.(32);Sobrino, A.(33);Rodríguez-Grau, M.C.(34);Elosua, A.(35);Montoro, M.(36);López-Sanromán, A.(1);Barreiro-de Acosta, M.(10);
(1)Hospital Universitario Ramón y Cajal, Department of Gastroenterology, Madrid, Spain;(2)Hospital Universitari Mutua Terrassa- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBERehd, Gastroenterology, Barcelona, Spain;(3)Hospital Clínic Barcelona, Gastroenterology, Barcelona, Spain;(4)Hospital Universitario Virgen del Rocío, Gastroenterology, Sevilla, Spain;(5)Hospital Universitario Marqués de Valdecilla- IDIVAL., Gastroenterology, Santander, Spain;(6)Hospital de la Santa Creu i Sant Pau, Gastroenterology, Barcelona, Spain;(7)Hospital Universitario y Politécnico La Fe, Gastroenterology, Valencia, Spain;(8)Hospital Universitari de Bellvitge, Gastroenterology, Barcelona, Spain;(9)Hospital Universitario 12 de Octubre, Gastroenterology, Madrid, Spain;(10)Hospital Clínico Universitario Santiago, Gastroenterology, Santiago de Compostela, Spain;(11)Hospital Universitari Germans Trias i Pujol, Gastroenterology, Badalona, Spain;(12)Hospital Universitario Galdakao, Gastroenterology, Bilbao, Spain;(13)Hospital Universitario Gregorio Marañón, Gastroenterology, Madrid, Spain;(14)Hospital Universitario Miguel Servet, Gastroenterology, Zaragoza, Spain;(15)Hospital Universitari Mutua Terrassa, Gastroenterology, Barcelona, Spain;(16)Hospital Universitari Doctor Josep Trueta, Gastroenterology, Girona, Spain;(17)Hospital Universitario Río Hortega, Gastroenterology, Valladolid, Spain;(18)Hospital Universitario Burgos, Gastroenterology, Burgos, Spain;(19)Hospital Universitario Puerta de Hierro Majadahonda, Gastroenterology, Madrid, Spain;(20)Complejo Hospitalario Navarra, Gastroenterology, Navarra, Spain;(21)Hospital Álvaro Cunqueiro, Gastroenterology, Vigo, Spain;(22)Hospital General Universitario Alicante- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBERehd- Instituto de Investigación Sanitaria y Biomédica de Alicante ISABIAL., Gastroenterology, Alicante, Spain;(23)Hospital del Mar, Gastroenterology, Barcelona, Spain;(24)Hospital Universitario Reina Sofía, Gastroenterology, Córdoba, Spain;(25)Hospital Universitario La Princesa- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBERehd- Instituto de Investigación Sanitaria Princesa IIS-IP., Gastroenterology, Madrid, Spain;(26)Complejo Hospitalario Universitario Ourense, Gastroenterology, Ourense, Spain;(27)Hospital Universitari Parc Taulí, Gastroenterology, Sabadell, Spain;(28)Hospital Universitario Nuestra Señora de Candelaria, Gastroenterology, Tenerife, Spain;(29)Hospital Universitario La Paz, Gastroenterology, Madrid, Spain;(30)Consorci Sanitari Terrassa, Gastroenterology, Barcelona, Spain;(31)Hospital Universitario Central Asturias, Gastroenterology, Oviedo, Spain;(32)Hospital Universitario de Canarias, Gastroenterology, Tenerife, Spain;(33)Hospital General Universitario Ciudad Real, Gastroenterology, Ciudad Real, Spain;(34)Hospital Universitario del Henares, Gastroenterology, Coslada, Spain;(35)Hospital García Orcoyen, Gastroenterology, Estella, Spain;(36)Hospital General Universitario San Jorge, Gastroenterology, Huesca, Spain; On behalf of the Young Group of GETECCU. RESERVO Study Group: Rodríguez Lago I Baston I Baltar R Huguet JM Hermida B Caballero-Mateos A Sánchez-Guillén L Bouhmidi A Pajares R
P373: Psoriasis and psoriasiform skin lesions in patients with Inflammatory Bowel Disease treated with infliximab: a pharmacokinetic analysisECCO'21 VirtualYear: 2021
Authors: Rodrigues, I.(1);Damião, F.(1);Serrazina, J.(1);Fernandes, S.(1);Bernardo, S.(1);Gonçalves, A.R.(1);Moura Santos, P.(1);Baldaia, C.(1);Valente, A.(1);Correia, L.(1);Tato Marinho, R.(1);
(1)Centro Hospitalar Universitário de Lisboa Norte - Hospital de Santa Maria, Gastroenterology, Lisbon, Portugal
P374: Safety and drug survival of methotrexate versus tioguanine after failure of conventional thiopurines in patients with Crohn’s disease.ECCO'21 VirtualYear: 2021
Authors: Savelkoul, E.(1);Maas, M.(1);Bourgonje, A.(2);Crouwel, F.(3);Russel, M.(4);Römkens, T.(5);De Boer, N.(3);Dijkstra, G.(2);Hoentjen, F.(1);
(1)Radboud University Medical Centre- Nijmegen- The Netherlands., Department of Gastroenterology and Hepatology, Nijmegen, The Netherlands;(2)University Medical Centre Groningen- Groningen- The Netherlands., Department of Gastroenterology and Hepatology, Groningen, The Netherlands;(3)Amsterdam University Medical Centre- VU University- AGEM Research Institute- Amsterdam- the Netherlands., Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands;(4)Medisch Spectrum Twente- Enschede- The Netherlands., Department of Gastroenterology and Hepatology, Enschede, The Netherlands;(5)Jeroen Bosch Ziekenhuis- 's-Hertogenbosch- The Netherlands., Department of Gastroenterology and Hepatology, 's-Hertogenbosch, The Netherlands
P375: A simulation study to evaluate the performance of a multiple imputation method to address missing data in an analysis of clinical effectiveness using the ImproveCareNow Registry of pediatric patients with Crohn’s diseaseECCO'21 VirtualYear: 2021
Authors: Zhang, N.(1,2);Liu, C.(1);King, E.(1,2);Chen, S.(1);Olano, K.(1);Steiner, S.(3);Colletti, R.(4);Saeed, S.(5);Strauss, R.(6);Volger, S.(6);Lo, K.H.(6);Wang, Y.(6);
(1)Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, Cincinnati, United States;(2)University of Cincinnati College of Medicine, Division of Biostatistics and Epidemiology, Cincinnati, United States;(3)Riley Hospital for Children/Indiana University School of Medicine, Pediatric Gastroenterology, Indianopolis, United States;(4)University of Vermont Children’s Hospital, Pediatrics, Burlington, United States;(5)Dayton Children’s Hospital/Wright State University, Pediatrics, Dayton, United States;(6)Janssen Research and Development- LLC, Immunology, Spring House, United States
P376: Improving stress and fatigue in a real-world setting among patients with Inflammatory Bowel Disease through a digital platformECCO'21 VirtualYear: 2021
Authors: Oddsson, S.(1);Gunnarsdottir, T.(1);Johannsdottir, L.(2);Amundadottir, M.(3);Frimannsdottir, A.(3);Ylanne, K.(4);Molander, P.(5);Islind, A.(2);Oskarsdottir, M.(2);Thorgeirsson, T.(1);
(1)Sidekick Health, Medical and Research Department, Kopavogur, Iceland;(2)Reykjavik University, Department of Computer Science, Reykjavik, Iceland;(3)Sidekick Health, Data Science Department, Kopavogur, Iceland;(4)Sidekick Health, Customer Success Department, Kopavogur, Iceland;(5)Helsinki University Hospital- Helsinki University, Abdominal Center- Gastroenterology, Helsinki, Finland