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P588: T cell response to SARS-CoV-2 mRNA vaccines by an interferon-gamma release immunoassay in patients with Inflammatory Bowel disease receiving anti-TNF and thiopurine treatmentECCO'22
Year: 2022
Authors: Mayorga Ayala, L.F.(1);Herrera-deGuise, C.(1);Esperalba, J.(2);Martinez-Gomez, X.(6);Céspedes Martinez, E.(1);Robles Alonso, V.(1);Jimenez, A.(1);Perez Martinez, Z.(1);Oller, E.(1);Ibarz, A.(1);Fernandez-Naval, C.(3);Martinez-Gallo, M.(4);Lopez Messeguer, M.(5);Casellas, F.(1);Borruel, N.(1);
(1)Unitat d’Atenció Crohn-Colitis, Servei d'Aparell Digestiu- Hospital Universitari Vall d'Hebron- Barcelona- Catalonia- Spain, Barcelona, Spain;(2)Universitat Autónoma de BarcelonaUAB- Barcelona- Catalonia- Spain, Servei de Microbiologia- Hospital Universitari Vall d'Hebron- Barcelona- Catalonia- Spain, Barcelona, Spain;(3)Universitat Autónoma de BarcelonaUAB- Barcelona- Catalonia- Spain, Servei de Microbiologia- Hospital Universitari Vall d'Hebron, Barcelona, Spain;(4)Universitat Autónoma de Barcelona UAB- Barcelona- Catalonia- Spain., Servei d'Immunologia- Hospital Universitari Vall d'Hebron- Barcelona- Catalonia- Spain, Barcelona, Spain;(5)Servei de Pneumologia, Hospital Universitari Vall d´Hebron- Barcelona, Barcelona, Spain;(6)Universitat Autónoma de BarcelonaUAB- Barcelona- Catalonia- Spain, Servei de Epidemiologia- Hospital Universitari Vall d'Hebron, Barcelona, Spain;
P589: Total thiopurine exposure and impact on the development of keratinocyte carcinomas in Inflammatory Bowel Disease patients; a case control studyECCO'22
Year: 2022
Authors: Jansen, F.M.(1);Lubeek, S.(2);den Broeder, N.(3);Savelkoul, E.(1);Marcus, C.(1);Hoentjen, F.(1,4);van Dop, W.(1);
(1)Radboud University Medical Center, Department of Gastroenterology and Hepatology, Nijmegen, The Netherlands;(2)Radboud University Medical Center, Department of Dermatology, Nijmegen, The Netherlands;(3)Radboud University Medical Center, Department of Rheumatology, Nijmegen, The Netherlands;(4)University of Alberta, Division of Gastroenterology- Department of Medicine, Edmonton, Canada;In cooperation with ‘PALGA’ (a nationwide network and registry of histo- and cytopathology in the Netherlands)
P590: Thromboprophylaxis use in paediatric inflammatory bowel disease: an international RAND appropriateness panelECCO'22
Year: 2022
Authors: Hansen, R.(1);Meade, S.(2);Torrente, F.(3);Kammermeier, J.(4);Croft, N.M.(5);de Ridder, L.(6);Wilson, D.C.(7);Klomberg, R.(6);Turner, D.(8);Martín-de-Carpi, J.(9);Bronsky, J.(10);Benchimol, E.(11);Amil-Dias, J.(12);Mack, D.R.(13);Walker, G.(14);Powar, M.(15);Burgess, N.(16);van Ommen, C.H.(17);Irving, P.M.(18);Samaan, M.(18);
(1)Royal Hospital for Children- Glasgow, Department of Paediatric Gastroenterology, Glasgow, United Kingdom;(2)King's College NHS Foundation Trust, Department of Gastroenterology, London, United Kingdom;(3)Cambridge University Hospitals NHS Foundation Trust, Department of Paediatric Gastroenterology, Cambridge, United Kingdom;(4)Evelina London Children’s Hospital, Department of Paediatric Gastroenterology, London, United Kingdom;(5)Queen Mary University of London, Centre for Immunobiology- Blizard Institute, London, United Kingdom;(6)Sophia Children's Hospital Erasmus MC, Department of Paediatric Gastroenterology, Rotterdam, The Netherlands;(7)University of Edinburgh, Child Life and Health, Edinburgh, United Kingdom;(8)Shaare Zedek Medical Centre- The Hebrew University of Jerusalem-, Department of Paediatric Gastroenterology, Jerusalem, Israel;(9)Hospital Sant Joan de Déu, Department of Paediatric Gastroenterology- Hepatology and Nutrition, Barcelona, Spain;(10)University Hospital Motol, Department of Paediatrics, Prague, Czech Republic;(11)The Hospital for Sick Children- University of Toronto, Division of Gastroenterology- Hepatology and Nutrition- Department of Paediatrics, Toronto, Canada;(12)Hospital Lusíadas, Department of Pediatric Gastroenterology, Porto, Portugal;(13)Children’s Hospital of Eastern Ontario and University of Ottawa, Department of Pediatrics, Ottawa, Canada;(14)Royal Hospital for Children- Glasgow, Department of Paediatric Surgery, Glasgow, United Kingdom;(15)Cambridge University Hospitals NHS Foundation Trust, Cambridge Colorectal Unit, Cambridge, United Kingdom;(16)The Royal London Hospital, Department of Paediatric Gastroenterology, London, United Kingdom;(17)Sophia Children's Hospital Erasmus MC, Department of Paediatric Hematology-Oncology, Rotterdam, The Netherlands;(18)Guy's and Saint Thomas' NHS Foundation Trust, IBD Unit, London, United Kingdom;
P591: Biological therapies and small molecules show to be efficacious in patients with moderate-to-severe ulcerative proctitis.ECCO'22
Year: 2022
Authors: Lemmens, P.(1);Guedelha Sabino, J.(1,2);Dubois, E.(1);Verstockt, B.(1,2);Vermeire, S.(1,2);Ferrante, M.(1,2);
(1)UZ Leuven, Departement of Gastro-enterology and Hepatology, Leuven, Belgium;(2)KU Leuven, Translational Research Centre for Gastrointestinal Disorders TARGID, Leuven, Belgium;
P592: Effectiveness and safety of thioguanine in thiopurine-naïve Inflammatory Bowel Disease patientsECCO'22
Year: 2022
Authors: Crouwel, F.(1);Bayoumy, A.B.(1);Mulder, C.J.J.(1);Peters, J.H.C.(2);Boekema, P.J.(3);Derijks, L.J.J.(4);De Boer, S.Y.(5);van de Meeberg, P.C.(5);Ahmad, I.(6);Buiter, H.J.C.(7);de Boer, N.K.(1);
(1)Amsterdam UMC- location VUmc, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands;(2)Rode Kruisziekenhuis, Department of Gastroenterology and Hepatology, Beverwijk, The Netherlands;(3)Maxima Medical Centre, Department of Gastroenterology and Hepatology, Veldhoven, The Netherlands;(4)Maxima Medical Centre, Department of Clinical Pharmacy and Pharmacology, Veldhoven, The Netherlands;(5)Slingeland Hospital, Department of Gastroenterology and Hepatology, Doetinchem, The Netherlands;(6)Streekziekenhuis Koningin Beatrix, Department of Gastroenterology and Hepatology, Winterswijk, The Netherlands;(7)Amsterdam UMC- location VUmc, Department of Radiology and Nuclear Medicine, Amsterdam, The Netherlands;
P593: Biologicals and small molecule combotherapies: promising experience in refractory IBD patientsECCO'22
Year: 2022
Authors: JuilleratMSc, P.(1);Martinho-Grueber, M.(1);Michetti, P.(2);
(1)Clinic for Visceral Surgery and Medicine, Department of Gastroenterology- University Hospital Bern Inselspital, Bern, Switzerland;(2)Gastroenterology Beaulieu Lausanne, Crohn and colitis center, Lausanne, Switzerland;
P594: Vedolizumab dose intensification does not always improve treatment persistence.ECCO'22
Year: 2022
Authors: Hilley, P.(1);Peterson, A.R.(1);Wong , D.(1,2);Hine, K.(1);Srinivasan, A.(1);Choy, M.C.(1,2);De Cruz, P.(1,2);
(1)Austin Health, Gastroenterology, Melbourne, Australia;(2)University of Melbourne, Department of Medicine- Austin Academic Centre, Melbourne, Australia;
P595: Validation of a predictive algorithm for thiopurine induced hepatotoxicity in IBD patientsECCO'22
Year: 2022
Authors: Van Moorsel, F.(1,2);Deben, D.(3);Creemers, R.(4,5);Winkens, B.(6);Pierik, M.(7);Bus, P.(8);Simsek, M.(9);de Boer, N.(9);van Bodegraven, A.(4);Wong, D.(3);
(1)Jeroen Bosch Hospital, Department of Pharmacy, s-Hertogenbosch, The Netherlands;(2)Bernhoven Hospital, Dept. of Clinical Pharmacy, Uden, The Netherlands;(3)Zuyderland Medical Centre, Dept. of Clinical Pharmacy- Clinical pharmacology and Toxicology, Sittard-Geleen/Heerlen, The Netherlands;(4)Zuyderland Medical Centre, Dept. of Gastroenterology- Geriatrics- Internal and Intensive Care Medicine Co-MIK, Sittard-Geleen/Heerlen, The Netherlands;(5)Maastricht University Medical Centre, 5Dev. of Gastroenterology and Hepatology, Maastricht, The Netherlands;(6)Maastricht University Medical Centre, Dept. of methodology and statistics, Maastricht, The Netherlands;(7)Maastricht University Medical Centre, Dev. of Gastroenterology and Hepatology, Maastricht, The Netherlands;(8)Laurentius Hospital, Dept. of Gastroenterology and Hepatology, Roermond, The Netherlands;(9)Amsterdam University Medical Centre, Dept. of Gastroenterology and Hepatology, Amsterdam, The Netherlands;
P596: Adalimumab use in Paediatric Inflammatory Bowel Disease: A single centre real-life experienceECCO'22
Year: 2022
Authors: El-Lababidi, N.(1,2);Frühauf, P.(2,2);
(1)General University Hospital in Prague- Czech Republic, Department of Paediatrics and Inherited Metabolic Disorders, Prague, Czech Republic;(2)First Faculty of Medicine- Charles University in Prague- Czech Republic, Department of Paediatrics and Inherited Metabolic Disorders, Prague, Czech Republic;
P597: Bone mineral density in patients after total proctocolectomy and pouch surgery due to Ulcerative Colitis have low bone mineral density, and low performance of DXA scans- a cross sectional studyECCO'22
Year: 2022
Authors: Pfeffer-Gik, T.(1,2);Godny, L.(1,2);Ollech , J.(1,2);Wasserberg, N.(2,3);Barkan , R.(1);White, I.(2,3);Yackobovitch Gavan, M.(4,5);Kraizler, M.(1);Yanai , H.(1,2);Dotan, I.(1,2);
(1)Rabin Medical center, Division of Gastroenterology, Petah Tikva, Israel;(2)Tel Aviv University, Sackler Faculty of Medicine, Tel Aviv, Israel;(3)Rabin Medical center, Division of Surgery Colorectal Unit, Petah Tikva, Israel;(4)Schneider Children's Medical Center of Israel, The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes- National Center for Childhood Diabetes, Petah Tikva, Israel;(5)Tel Aviv University, Dept. of Epidemiology and Preventive Medicine- School of Public Health- Sackler Faculty of Medicine, Tel Aviv, Israel;
P598: Indicators for inadequate response among patients with Ulcerative Colitis treated with advanced therapies in German clinical practiceECCO'22
Year: 2022
Authors: Bokemeyer, B.(1);Picker, N.(2);Kromer, D.(2);Rosin, L.(3);Patel, H.(4);
(1)Gastroenterology Practice, Minden, Minden, Germany;(2)Ingress Health HWM, GmbH, Wismar, Germany;(3)Galapagos Biopharma Deutschland, GmbH, München, Germany;(4)Galapagos, Nv, Mechelen, Belgium;
P599: Azathioprine in the prevention of anti-infliximab antibody formation: A pilot dose-finding studyECCO'22
Year: 2022
Authors: Kojecký, V.(1,2);Wasserbauer , M.(3);Keil, R.(3);
(1)Masaryk University, Faculty of Medicine, Brno, Czech Republic;(2)Bata regional hospital, Department of Internal medicine, Zlin, Czech Republic;(3)Charles University in Prague and Motol University Hospital, Department of Internal Medicine, Prague, Czech Republic;
P600: Serologic response to COVID-19 vaccines in IBD patients: a prospective studyECCO'22
Year: 2022
Authors: Martin ArranzPhD- MD, M.D.(1);García Ramírez, L.(2);Montero Vega, D.(3);Martín-Arraz, E.(2);Sánchez Azofra, M.(2);Poza Cordon, J.(2);Rueda Garcia, J.L.(2);Noci Belda, J.(2);Verges Martínez-Meco, T.(2);Blanco San Miguel, P.(2);Suarez Ferrer, C.(2);
(1)La Paz University Hospital. Universidad Autónoma de Madrid. IdiPaz, Gastroenterolgy, Madrid, Spain;(2)La Paz University Hospital.IdiPaz, Gastroenterolgy, Madrid, Spain;(3)La Paz University Hospital., Microbiology, Madrid, Spain;
P601: Real World Evidence on the comparative effectiveness of Ustekinumab vs anti-TNF in Crohn’s disease with Propensity Score adjustment: maintenance phase results from the prospective observational RUN-CD studyECCO'22
Year: 2022
Authors: Bokemeyer, B.(1);Plachta-Danielzik, S.(2);di Giuseppe, R.(2);Deppe, H.(3);Mohl, W.(4);Teich, N.(5);Hoffstadt, M.(6);Schweitzer, A.(7);von der Ohe, M.(8);Gauss, A.(9);Atrya, R.(10);Krause, T.(11);Blumenstein, I.(12);Höchstödter, J.(2);Hartmann, P.(3);Schreiber, S.(13);
(1)Interdisciplinary Crohn Colitis Centre Minden- Germany and Clinic of General Internal Medicine I- University Hospital Schleswig-Holstein- Campus Kiel- Germany, Gastroenterology, Minden, Germany;(2)Competence Network IBD, Kiel-Germany, Kiel, Germany;(3)Gastroenterology Practice Minden, Gastroenterology, Minden, Germany;(4)Gastroenterology Practice Saarbrücken- Germany, Gastroenterology, Saarbrücken, Germany;(5)Internistische Gemeinschaftspraxis für Verdauungs- und Stoffwechselkrankheiten Leipzig, Gastroenterology, Leipzig, Germany;(6)Gastroenterology Practice Isterlohn, Gastroenterology, Iserlohn, Germany;(7)Gastroenterology Practice Münster, Gastroenterology, Münster, Germany;(8)Gastroenterology Practice Herne, Gastroenterology, Herne, Germany;(9)University Clinics of Heidelberg-Heidelberg-Germany, Department of Gastroenterology- Internal Medicine IV, Heidelberg, Germany;(10)University Hospital Erlangen- University of Erlangen-Nürnberg Erlangen- Erlangen- Germany, Department of Medicine- Medical Clinic 1, Erlangen, Germany;(11)Gastroenterology Practice Kassel, Gastroenterology, Kassel, Germany;(12)Johann Wolfgang Goethe University Clinic- 60590 Frankfurt- Germany, Department of Gastroenterology and Clinical Nutrition, Frankfurt, Germany;(13)University Hospital Schleswig-Holstein- Campus Kiel- Germany, Clinic of General Internal Medicine I, Kiel, Germany;
P602: Tofacitinib treatment prevents post-operative recurrence of Crohn’s Disease modeled by ileocecal resection in HLA-B27 transgenic rats.ECCO'22
Year: 2022
Authors: Blondeaux, A.(1);Speca, S.(2);Valibouze, C.(3);Lambin, T.(1);Dubuquoy, C.(2);Titecat, M.(4);Genoscreen, L.(5);Neut, C.(6);Genin, M.(7);Zerbib, P.(3);Foligne, B.(6);Desreumaux, P.(1);
(1)Univ. Lille- Inserm- Infinite-U1286, CHU Lille- Service des maladies de l'appareil digestif, Lille, France;(2)Univ. Lille- Inserm- Infinite-U1286, CHU Lille, Lille, France;(3)Univ. Lille - Inserm - INFINITE - U1286, CHU Lille - Département de Chirurgie Digestive, Lille, France;(4)Univ. Lille- Inserm- Infinite-U1286, CHU Lille- Service de Bactériologie, Lille, France;(5)Genoscreen, Lille, Lille, France;(6)Univ. Lille- Inserm- Infinite-U1286, Faculté de Pharmacie, Lille, France;(7)Univ. Lille, Ulr 2694, Lille, France;
P603: INSPIRE: 6-month interim analysis from an observational post-marketing registry on the effectiveness and safety of darvadstrocel in patients with Crohn’s disease and complex perianal fistulasECCO'22
Year: 2022
Authors: Zmora, O.(1);Baumgart, D.C.(2);Faubion, W.(3);Ferrante, M.(4);Gecse, K.(5);Genestin, E.(6);Geransar, P.(6);Hantsbarger, G.(7);Karki, C.(8);Tozer, P.(9);Panés, J.(10);
(1)Shamir Medical Center, Department of Surgery, Tel Aviv, Israel;(2)University of Alberta, Division of Gastroenterology, Edmonton AB, Canada;(3)Mayo Clinic, Gastroenterology and Hepatology, Rochester- MN, United States;(4)University Hospitals Leuven- KU Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium;(5)Amsterdam UMC, Gastroenterology & Hepatology, Amsterdam, Netherlands Antilles;(6)Takeda pharmaceuticals International AG, Global Medical Affairs - Rare GI, Zurich, Switzerland;(7)Takeda Pharmaceuticals USA Inc., Safety and Health Value Statistics, Cambridge- MA, United States;(8)Takeda Pharmaceuticals USA- Inc., Global Evidence and Outcomes, Cambridge- MA, United States;(9)St Mark’s Hospital and Academic Institute, Fistula Research Unit, London, United Kingdom;(10)Hospital Clinic de Barcelona, IDIBAPS- CIBERehd, Barcelona, Spain;
P604: Infection Risk in Elderly Patients with Inflammatory Bowel Disease under anti-TNF, ustekinumab or vedolizumab biologic therapies: A Prospective Multicenter observational One-Year follow-up comparative study.ECCO'22
Year: 2022
Authors: Bozon, A.(1);Serrero, M.(2);Caillo, L.(3);Gilletta, C.(4);Benezech, A.(5);Nancey, S.(6);Combes, R.(7);Danan, G.(8);Akouete, S.(1);Pages, L.(1);Bourgaux, J.F.(3);Boivineau, L.(1);Meszaros, M.(1);Altwegg, R.(1);
(1)CHU Montpellier Saint Eloi Hospital, Gastroenterology, Montpellier Cedex 5, France;(2)CHU Marseille Hospital, Gastroenterology, Marseille, France;(3)CHU Nîmes Hospital, Gastroenterology, Nîmes, France;(4)CHU Toulouse Hospital, Gastroenterology, Toulouse, France;(5)CH Avignon Hospital, Gastroenterology, Avignon, France;(6)CHU Lyon Hospital, Gastroenterology, Lyon, France;(7)Clinique Beausoleil, Gastroenterology, Montpellier, France;(8)Gastrodoc, Gastroenterology, Montpellier, France;
P605: Immunogenicity and safety of standard and third dose SARS-CoV-2 vaccination in patients with immune-mediated inflammatory diseases; a prospective cohort studyECCO'22
Year: 2022
Authors: Jørgensen, K.K.(1); Syversen, S.W.(2); Jyssum, I.(2,3);Tveter, A.T.(2);Tran, T.T.(4);Sexton, J.(2);Provan, S.A.(2);Mjaaland , S.(5);Warren, D.J.(6);Kvien, T.K.(2,3);Grødeland , G.(3,4); Nissen-Meyer, L.S.(4);Ricanek, P.(1);Chopra , A.(4);Andersson, A.M.(4);Kro, G.B.(6);Jahnsen, J.(1,3);Munthe, L.A.(4,7);Haavardsholm, E.A.(2,3); Vaage, J.T.(3,4);Lund-Johansen, F.(3,8);Goll-, G.L.(2);
(1)Akershus University Hospital, Dept. of Gastroenterology, Oslo, Norway;(2)Diakonhjemmet Hospital, Division of Rheumatology and Research, Oslo, Norway;(3)Institute of Clinical Medicine, University of Oslo, Oslo, Norway;(4)Oslo University Hospital, Department of Immunology, Oslo, Norway;(5)Norwegian Institute of Public Health, Norwegian Institute of Public Health, Oslo, Norway;(6)Oslo University Hospital, Department of Medical Biochemistry, Oslo, Norway;(7)University of Oslo, KG Jebsen Centre for B cell Malignancies, Oslo, Norway;(8)University of Oslo, ImmunoLingo Convergence Center, Oslo, Norway;
P606: Use of TNF-α-antagonists and systemic steroids is associated with attenuated immunogenicity against SARS-CoV-2 in fully vaccinated patients with Inflammatory Bowel DiseaseECCO'22
Year: 2022
Authors: Otten , A.T.(1);Bourgonje , A.R.(1);Horinga , P.P.(1);van der Meulen , H.H.(1);van Leer-Buter , C.C.(2);Dijkstra , G.(1);Visschedijk , M.C.(1);
(1)University Medical Center Groningen, Gastroenterology & Hepatology, Groningen, The Netherlands;(2)University Medical Center Groningen, Medical Microbiology, Groningen, The Netherlands;
P607: Efficacy and safety of tofacitinib in Ulcerative Colitis patients with extraintestinal manifestations in OCTAVE OpenECCO'22
Year: 2022
Authors: Rubin , D.T.(1);Vavricka , S.R.(2);Armuzzi , A.(3);Dubinsky , M.C.(4);Sharara , A.I.(5);Modesto , I.(6);Fellmann , M.(7);Liguori , G.(8);Lawendy , N.(9);Cadatal , M.J.(10);Lichtenstein , G.R.(11);
(1)-, University of Chicago Medicine Inflammatory Bowel Disease Center, Chicago- IL, United States;(2)University Hospital Zürich, Department of Gastroenterology and Hepatology, Zürich, Switzerland;(3)Fondazione Policlinico Universitario A. Gemelli IRCCS – Università Cattolica del Sacro Cuore, IBD Unit, Rome, Italy;(4)-, Icahn School of Medicine at Mount Sinai, New York- NY, United States;(5)American University of Beirut Medical Center, Division of Gastroenterology, Beirut, Lebanon;(6)-, Pfizer Inc, New York- NY, United States;(7)-, Pfizer Switzerland AG, Zürich, Switzerland;(8)-, Pfizer Srl, Rome, Italy;(9)-, Pfizer Inc, Collegeville- PA, United States;(10)-, Pfizer Inc, Manila, Philippines;(11)Perelman School of Medicine at the University of Pennsylvania, Division of Gastroenterology, Philadelphia- PA, United States;