P905: Predictive pharmacogenetic risk of pancreatitis in Inflammatory Bowel Disease patients treated with thiopurines: a case-control study from the ENEIDA registry.ECCO’23 CopenhagenYear: 2023
Authors: Guerra Marina, I.(1)*;Barros, F.(2);Chaparro, M.(3,4);Benítez, J.M.(5);Martín Arranz, M.D.(6);de Francisco, R.(7);Piqueras, M.(8);de Castro, L.(9);Carbajo, A.Y.(10);Bermejo, F.(1);Mínguez, M.(11);Gutiérrez, A.(4,12);Mesonero, F.(13);Cañete, F.(4,14);González-Muñoza, C.(15);Calvo, M.(16);Sicilia, B.(17);Alfambra, E.(4,18);Tardillo, C.A.(19);Rivero, M.(20);Lucendo, A.J.(4,21);Bujanda, L.(4,22);Van Domselaar, M.(23);Almela, P.(24);Ramos, L.(25);Fernández Sánchez, M.(26);Hinojosa, E.(27);Verdejo, C.(28);Gimenez, A.(29);Rodríguez-Lago, I.(30);Manceñido, N.(31);Pérez Calle, J.L.(32);Moreno, M.D.P.(33);Delgado-Guillena, P.G.(34);Antolín, B.(35);Ramírez de la Piscina, P.(36);Casanova, M.J.(3,4);Carracedo, Á.(2);Domènech, E.(4,14);Gisbert, J.P.(3,4);
(1)Hospital Universitario de Fuenlabrada, Gastroenterology, Fuenlabrada, Spain;(2)Fundación Pública Galega de Medicina Xenómica - Sergas, Unidad de Medicina Molecular, Santiago de Compostela, Spain;(3)Hospital Universitario de La Princesa- Instituto de Investigación Sanitaria Princesa IIS-Princesa- UAM, Gastroenterology, Madrid, Spain;(4)Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Gastroenterology, Spain, Spain;(5)Hospital Universitario Reina Sofía e Instituto Maimónides de Investigación Biomédica de Córdoba IMIBIC, Gastroenterology, Córdoba, Spain;(6)Hospital Universitario La Paz, Gastroenterology, Madrid, Spain;(7)Hospital Universitario Central de Asturias- Instituto de Investigación Sanitaria del Principado de Asturias ISPA, Gastroenterology, Oviedo, Spain;(8)Consorci Sanitari Terrasa, Gastroenterology, Terrasa, Spain;(9)Hospital Alvaro Cunqueiro-Complexo Hospitalario Universitario de Vigo- Instituto de Investigación Biomédica Galicia Sur, Gastroenterology, Vigo, Spain;(10)Hospital Universitario Rio Hortega, Gastroenterology, Valladolid, Spain;(11)Hospital Clínico Universitario de Valencia, Gastroenterology, Valencia, Spain;(12)Hospital General Universitario Dr Balmis de Alicante. ISABIAL, Gastroenterology, Alicante, Spain;(13)Hospital Universitario Ramón y Cajal, Gastroenterology, Madrid, Spain;(14)Hospital Universitari Germans Trias i Pujol, Gastroenterology, Badalona, Spain;(15)Hospital de la Santa Creu i Sant Pau, Gastroenterology, Barcelona, Spain;(16)Hospital Universitario Puerta de Hierro-Majadahonda, Gastroenterology, Madrid, Spain;(17)Hospital Universitario de Burgos, Gastroenterology, Burgos, Spain;(18)Hospital Clínico Universitario “Lozano Blesa” e Instituto de Investigación Sanitaria de Aragón IIS Aragón, Gastroenterology, Zaragoza, Spain;(19)Hospital Universitario Nuestra Señora Candelaria, Gastroenterology, Santa Cruz de Tenerife, Spain;(20)Hospital Universitario Marqués de Valdecilla e IDIVAL, Gastroenterology, Santander, Spain;(21)Hospital General de Tomelloso, Gastroenterology, Ciudad Real, Spain;(22)Hospital Donostia/Instituto Biodonostia- Universidad del País Vasco UPV/EHU, Gastroenterology, Donostia/San Sebastian, Spain;(23)Hospital Universitario de Torrejón y Universidad Francisco de Vitoria, Gastroenterology, Madrid, Spain;(24)Hospital General Universitari de Castelló, Gastroenterology, Castelló, Spain;(25)Hospital Universitario de Canarias, Gastroenterology, Santa Cruz de Tenerife, Spain;(26)Hospital General Universitario de Elche, Gastroenterology, Alicante, Spain;(27)Hospital de Manises, Gastroenterology, Valencia, Spain;(28)Hospital General Universitario de Ciudad Real, Gastroenterology, Ciudad Real, Spain;(29)Hospital Sant Joan de Déu-Althaia, Gastroenterology, Manresa, Spain;(30)Hospital de Galdakao, Gastroenterology, Galdakao, Spain;(31)Hospital Universitario Infanta Sofía, Gastroenterology, San Sebastián de los Reyes, Spain;(32)Hospital Universitario Fundación Alcorcón, Gastroenterology, Madrid, Spain;(33)Hospital General La Mancha Centro, Gastroenterology, Alcázar de San Juan- Ciudad Real, Spain;(34)Hospital General de Granollers, Gastroenterology, Granollers, Spain;(35)Hospital Clínico Universitario de Valladolid, Gastroenterology, Valladolid, Spain;(36)Hospital Universitario de Áraba, Gastroenterology, Vitoria, Spain;On behalf of the ENEIDA project of GETECCU.
P906: Prevalence and CARD9 IBD risk variant rs4077515 in a Chilean IBD Cohort.ECCO’23 CopenhagenYear: 2023
Authors: Pérez, T.(1,2)*;Bustamante, M.L.(3);Magne, F.(3);Alvares, D.(4);Álvarez-Lobos, M.(1);Hernandez-Rocha, C.(1);Aguliar, N.(1);Azocar, L.(1);Baez, P.(5);Zazueta, A.(3);Estela, R.(2);Escobar, S.(2);Silva, V.(2);De la Vega, A.(2);Arriagada, E.(2);Espino, A.(1);Miquel, J.F.(1);Travisany, D.(6);
(1)Pontificia Universidad Católica de Chile, Department of Gastroenterology, Santiago, Chile;(2)Hospital San Borja Arriarán, Department of Gastroenterology, Santiago, Chile;(3)University of Chile, Faculty of Medicine- ICBM, Santiago, Chile;(4)University of Cambridge, MRC Biostatistics Unit, Cambridge, United Kingdom;(5)University of Chile, Center for Mathematical Modeling, Santiago, Chile;(6)Universidad de las Americas, NIDS- Núcleo de Investigación en Data Science- Facultad de Ingeniería y Negocios, Santiago, Chile;
P907: NOD2 mutations are associated with the development of inflammatory and progressive digestive tract damage in Crohn's diseaseECCO’23 CopenhagenYear: 2023
Authors: Behnisch, S.(1)*;Reiner, J.(1);Witte, M.(2);Holle, A.(1);Schäffler, H.(1);Huth, A.(1);Jaster, R.(1);Lamprecht, G.(1);
(1)Rostock University Medical Center, Division of Gastroenterology- Department of Medicine II, Rostock, Germany;(2)Rostock University Medical Center, Department of General- Visceral- Thoracic- Vascular and Transplant Surgery, Rostock, Germany;
P908: Faecal Microbiota Transplantation refurbishes the crypt-associated microbiota in Ulcerative colitisECCO’23 CopenhagenYear: 2023
Authors: Markandey, M.(1)*;Bajaj, A.(1);Verma, M.(1);Virmani, S.(1);Singh, M.(1);Gaur, P.(2);Das, P.(3);Srikanth, C.(2);Makharia, G.(1);Kedia, S.(1);Ahuja, V.(1);
(1)All India Institute of Medical Sciences, Department of Gastroenterology, New Delhi, India;(2)Regional Centre for Biotechnology, 3rd milestone Gurugram-Faridabad Expressway, Faridabad, India;(3)All India Institute of Medical Sciences, Department of Pathology, New Delhi, India;
P909: Microbiome dynamics leading up to and during pregnancy in a matched IBD-control cohortECCO’23 CopenhagenYear: 2023
Authors: Binyamin, D.(1); Turjeman, S.(1);Koren, O.(1);Ben Ya'acov, A.(2);Gold, G.(2);Goldenberg, R.(2);Bar-Gil Shitrit, A.(2)*;
(1)Bar-Ilan University, Azrieli Faculty of Medicine, Safed, Israel;(2)Shaare Zedek Medical Center, Digestive Diseases Institute, Jerusalem, Israel;
P910: Emerging role of IL-33/ST2 and Gut Microbiota axis in the inflammatory process of ulcerative colitis patients with ileal pouch-anal anastomosis.ECCO’23 CopenhagenYear: 2023
Authors: Lopetuso, L.R.(1)*;Vetrone, L.(1);Petito, V.(1);Pugliese, D.(1);Parisio, L.(1);Laterza, L.(1);Gasbarrini, A.(1);Scaldaferri, F.(1);Papa, A.(1);
(1)Fondazione Policlinico Universitario "A. Gemelli" IRCCS- Università Cattolica del Sacro Cuore, IBD Unit- Centro Malattie dell'Apparato Digerente - CEMAD, Roma, Italy;
P911: The changes in the faecal microbiome and metabolome in Crohn's disease after treatment with anti-TNFα antibodies are of secondary originECCO’23 CopenhagenYear: 2023
Authors: Hurych, J.(1,2)*;Mascellani Bergo, A.(3);Lerchová, T.(2);Hlináková, L.(1);Kubát , M.(2);Malcová, H.(4);Cebecauerová, D.(4);Schwarz, J.(5);Karásková, E.(6);Hecht, T.(7);Vyhnánek, R.(7);Ťoukálková, L.(8);Dotlačil, V.(9);Kobrová, K.(10);Čížková, A.(11);Horváth, R.(4);Bronsky, J.(2);Havlík, J.(3);Hradský, O.(2);Cinek, O.(2);
(1)Charles University- Second Faculty of Medicine, Department of Medical Microbiology, Prague, Czech Republic;(2)Charles University- Second Faculty of Medicine, Department of Paediatrics, Prague, Czech Republic;(3)Czech Univesity of Life Sciences-Faculty of Agrobiology- Food and Natural Resources, Department of Food Science, Prague, Czech Republic;(4)Motol University Hospital, Department of Pediatric and Adult Rheumatology, Prague, Czech Republic;(5)Charles University- Faculty of Medicine in Pilsen, Department of Paediatrics, Pilsen, Czech Republic;(6)Palacky University Olomouc- Faculty of Medicine-, Department of Paediatrics, Olomouc, Czech Republic;(7)Charles University- First Faculty of Medicine, Department of Paediatrics, Prague, Czech Republic;(8)Tomas Bata Hospital, Department of Paediatrics, Zlin, Czech Republic;(9)Charles University- Second Faculty of Medicine, Department of Paediatric Surgery, Prague, Czech Republic;(10)Masaryk Hospital, Department of Paediatrics, Usti nad Labem, Czech Republic;(11)Synlab Czech- Inc, Sampling station Prague 7, Prague, Czech Republic;
P912: Increased Primary Bile Acids with Ileocolonic Resection Impact Ileal Inflammation and Gut Microbiota in Inflammatory Bowel DiseaseECCO’23 CopenhagenYear: 2023
Authors: Battat, R.(1)*;Scherl, E.(2);Lukin, D.(2);Charilaou, P.(3);Mahtani, P.(4);Gerber, J.(2);Gandara, J.(5);Dündar, F.(6);Zumbo , P.(6);Betel , D.(6);Guo , C.J.(7);Longman, R.(2);
(1)University of Montreal, Gastroenterology and Hepatology, Montreal, Canada;(2)Weill Cornell Medicine, Gastroenterology, New York, United States;(3)Atrium Health, Gastroenterology and Hepatology, Charlotte, United States;(4)Weill Cornell Medicine, Gastroenterology and Hepatology, New York, United States;(5)Weill Cornell Medicine, Microbiome Core, New York, United States;(6)Weill Cornell Medicine, Applied Bioinformatics Core, New York, United States;(7)Weill Cornell Medicine, Medicine, New York, United States;Jill Roberts Institute Live Cell Bank
P915: Uncovering the role of Archaea in the pathogenesis of Inflammatory bowel diseaseECCO’23 CopenhagenYear: 2023
Authors: Singh, P.(1);Murugesan, S.(1); Kumar, M.(1); Saadaoui, M.(1);Elhag, D.A.(1);Hendaus, M.A.(2); Ibrahim, N.(3); Al-Mudhaka, F.(3); AbuHazima, K.(3); Akobeng, A.(3);Elawad , M.(3);Al Khodor, S.(1)*;
(1)Sidra Medicine, Research, Doha, Qatar;(2)Sidra Medicine, Pediatrics, Doha, Qatar;(3)Sidra Medicine, Pediatrics Gastroenterology- Hepatology and Nutrition, Doha, Qatar;
P916: Small bowel permeability improvement is associated with microbial changes seen in mild to moderate active paediatric Crohn's disease patients on nutritional therapyECCO’23 CopenhagenYear: 2023
Authors: VerburgtMD, C.(1,2)*;Dunn, K.(3);Sigall Boneh, R.(4);Wine, E.(5);Benninga, M.(1);de Jonge, W.(2,6);Van Limbergen, J.(1,2);
(1)Emma Children's Hospital- Amsterdam University Medical Centers, Dpt of Paediatric Gastroenterology and Nutrition, Amsterdam, The Netherlands;(2)Amsterdam Gastroenterology Endocrinology Metabolism- University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam, The Netherlands;(3)Dalhousie University, Dpt of Biology, Halifax, Canada;(4)Sackler Faculty of Medicine- Tel Aviv University, Wolfson Medical Center, Tel Aviv, Israel;(5)Stollery Children's Hospital- University of Alberta, Division of Paediatric Gastroenterology, Edmonton, Canada;(6)University of Bonn, Dpt of Surgery, Bonn, Germany;
P917: Intestinal complement interacts with commensal microbiota and provides pattern recognition in Inflammatory Bowel DiseaseECCO’23 CopenhagenYear: 2023
Authors: Reider, S.(1)*;Posch, W.(2);Koch, R.(3);Orth-Höller, D.(4);Würzner, R.(2);Wilflingseder, D.(2);Tilg, H.(3);Moschen, A.(1);
(1)Johannes Kepler University and Kepler University Hospital, Department of Internal Medicine 2 - Gastroenterology and Hepatology, Linz, Austria;(2)Medical University Innsbruck, Department for Hygiene- Microbiology and Public Health, Innsbruck, Austria;(3)Medical University Innsbruck, Department of Internal Medicine I, Innsbruck, Austria;(4)MB-LAB, Mikrobiologisches Labor, Innsbruck, Austria;
P918: Clostridium butyricum inhibits epithelial-mesenchymal transition of intestinal carcinogenesis through downregulating METTL3ECCO’23 CopenhagenYear: 2023
Authors: Zhang, K.(1)*;Dong, Y.(1);Li, M.(1);Zhang, W.(1);Ding, Y.(1);Wang, X.(1);Chen, D.(1);Liu, T.(1);Wang, B.(1);Zhong, W.(1);Cao, H.(1)*;
(1)General Hospital- Tianjin Medical University- National Key Clinical Specialty- Tianjin Institute of Digestive Diseases- Tianjin Key Laboratory of Digestive Diseases, Department of Gastroenterology and Hepatology, Tianjin, China;
P919: Gut microbial signature and phenotype-specific Indicators in fecal microbiota of Korean patients with Inflammatory Bowel DiseaseECCO’23 CopenhagenYear: 2023
Authors: Lee, C.K.(1)*;Oh, S.J.(1);Kim, H.J.(1);Kim, B.H.(2);Kim, B.K.(3);Park, Y.K.(3);Yang, B.G.(3);
(1)Kyung Hee University, Gastroenterology, Seoul, Korea- Republic Of;(2)Kyung Hee University, Clinical Pharmacology and Therapeutics, Seoul, Korea- Republic Of;(3)GI Biome Inc., Research Institute, Seongnam, Korea- Republic Of;
P920: Gut microbiota at diagnosis is associated with clinical features and future disease course in Inflammatory Bowel Disease: Data from IBSEN III, a new large Norwegian population-based inception cohortECCO’23 CopenhagenYear: 2023
Authors: Hyll Hansen, S.(1,2,3)*;Gjerstad Maseng, M.(3,4,5);Björkqvist, O.(6);Halfvarsson, J.(7);Bang, C.(8);Detlie, T.E.(9,10);Huppertz-Hauss, G.(11);Kristensen, V.(5,12);Opheim, R.(5,13);Perminow, G.(14);Asak, Ø.(15);Bengtson, M.B.(10);Boyar Cetinkaya, R.(16);Henriksen, M.(17);Hovde, Ø.(3,18);Medhus, A.W.(3,5);Pallenschat, J.(19);Strande, V.(3,20,21);Valeur, J.(21);Svendsen Vatn, S.(10);Bergene Aabrekk, T.(22);Høivik, M.L.(5);Hov, J.R.(1,2,3,23);
(1)Oslo University Hospital, Norwegian PSC Research Center- Department of Transplantation Medicine- Division of Surgery- Inflammatory Diseases and Transplantation, Oslo, Norway;(2)Oslo University Hospital, Research Institute of Internal Medicine- Division of Surgery- Inflammatory Diseases and Transplantation, Oslo, Norway;(3)University of Oslo, Institute of Clinical Medicine- Faculty of Medicine, Oslo, Norway;(4)Bio-Me, Bio-Me, Oslo, Norway;(5)Oslo University Hospital, Department of Gastroenterology, Oslo, Norway;(6)Örebro University, School of Medical Sciences, Örebro, Sweden;(7)Örebro University, Department of Gastroenterology- Faculty of Medicine and Health, Örebro, Sweden;(8)Christian-Albrechts-University of Kiel, Institute of Clinical Molecular Biology, Kiel, Germany;(9)University of Oslo, University of Oslo, Oslo, Norway;(10)Akershus University Hospital, Department of Gastroenterology, Lørenskog, Norway;(11)Telemark Hospital, Department of Gastroenterology, Skien, Norway;(12)Lovisenberg Diaconal Hospital, Unger-Vetlesen Insitute, Oslo, Norway;(13)University of Oslo, Department of Public Health- Institute of Health and Society, Oslo, Norway;(14)Oslo University Hospital, Pediatric Department, Oslo, Norway;(15)Innlandet Hospital Trust, Medical Department, Oslo, Norway;(16)Diakonhjemmet Hospital, Department of Medicine, Oslo, Norway;(17)Østfold Hospital Trust, Department of Gastroenterology, Grålum, Norway;(18)Innlandet Hospital Trust, Department of Medicine, Gjøvik, Norway;(19)Sørlandet Hospital Flekkefjord, Department of Medicine, Flekkefjord, Norway;(20)Lovisenberg Diaconal Hospital, Department of Medicine/Gastroenterology, Oslo, Norway;(21)Lovisenberg Diaconal Hospital, Unger-Vetlesen Institute, Oslo, Norway;(22)Vestfold Hospital Trust, Medical Department, Tønsberg, Norway;(23)Oslo University Hospital, Section of Gastroenterology- Department of Transplantation Medicine- Division of Surgery- Inflammatory Diseases and Transplantation, Oslo, Norway;
P921: FMT in UC is associated with a decrease in Bacteroides-2 enterotype and response with baseline RNA and microbiota signaturesECCO’23 CopenhagenYear: 2023
Authors: Deleu, S.(1)*;Caenepeel , C.(1);Verstockt, S.(1);Vazquez Castellanos, J.F.(2,3);Arnauts , K.(1);Braekeleire, S.(1);Machiels, K.(1);Baert, F.(4);Mana, F.(5);Pouillon, L.(6);Hindryckx, P.(7);Lobaton Ortega, T.(7);Louis, E.(8);Franchimont, D.(9);Verstockt , B.(1,10);Ferrante, M.(1,10);Sabino, J.(1,10);Vieira-Silva, S.(2,11,12);Falony, G.(2,3,13);Raes, J.(2,3);Vermeire, S.(1,10);
(1)KU Leuven, Department of Chronic Diseases- Metabolism & Ageing CHROMETA, Leuven, Belgium;(2)KU Leuven, Department of Microbiology and Immunology, Leuven, Belgium;(3)VIB, Center for microbiology, Leuven, Belgium;(4)AZ Delta, Department of Gastroenterology and Hepatology, Roeselare, Belgium;(5)University Hospitals Brussels, Department of Gastroenterology and Hepatology, Brussels, Belgium;(6)Imelda, Department of Gastroenterology and Hepatology, Bonheiden, Belgium;(7)University Hospital Gent, Department of Gastroenterology and Hepatology, Gent, Belgium;(8)CHU Liège, Department of Gastroenterology and Hepatology, Liège, Belgium;(9)Erasmus Hospital Brussels, Department of Gastroenterology and Hepatology, Brussels, Belgium;(10)University Hospital Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium;(11)Institute of Molecular Biology IMB, Institute of Molecular Biology IMB, Mainz, Germany;(12)University Medical Center of the Johannes Gutenberg-University Mainz, Institute of Medical Microbiology and Hygiene and Research Center for Immunotherapy FZI, Mainz, Germany;(13)University Medical Center of the Johannes Gutenberg-University Mainz, Institute of Medical Microbiology and Hygiene and Research Center for Immunotherapy FZI, Mainz, Belgium;
P922: Gut microbiome and mycobiome in inflammatory bowel disease patients with Clostridium difficile infectionECCO’23 CopenhagenYear: 2023
Authors: Yu, S.(1)*;Ge, X.(2);Tan, B.(1);Tian, B.(1);Shi, Y.(1);Dai, Y.(1);Hu, S.(3);Li, Y.(1);Qian, J.(1);
(1)Peking Union Medical College Hospital- Peking Union Medical College and Chinese Academy of Medical Sciences, Department of Gastroenterology, Beijing, China;(2)Institute of Microbiology- Chinese Academy of Sciences, Microbial Resource and Big Data Center, Beijing, China;(3)Institute of Microbiology- Chinese Academy of Sciences, State Key Laboratory of Microbial Resources, Beijing, China;
P923: The pre-treatment gut microbiome at adult IBD inception: Initial signals from the Birmingham inception cohortECCO’23 CopenhagenYear: 2023
Authors: Rimmer, P.(1)*;Cheesbrough, J.(1);Iqbal, A.(2);Sharma, N.(1);Iqbal, T.(1);Quraishi, N.(1);
(1)University Hospitals Birmingham NHS Foundation Trust, Gastroenterology, Birmingham, United Kingdom;(2)University of BIrmingham, Institute of Cardiovascular Sciences, Birmingham, United Kingdom;
