P1190: Generation of blood-derived reference samples with endogenous cytokinesECCO'25Year: 2025
Authors: Bain-Wendlinger , C.(1)*;Lavocat , F.(2);Poyau , A.(2);Silva , J.(3);Cousin , E.(2);Serraz , C.(3);
(1)KCAS Bio, Scientific direction, LYON, France;(2)KCAS Bio, Method development, lyon, France;(3)KCAS Bio, Bioanalysis, Lyon, France;
P1191: Early Clinical, Biological, and Sonographic Response in Ileal Crohn’s Disease Patients Treated with Upadacitinib: A Single-Centre Real-World ExperienceECCO'25Year: 2025
Authors: Maria, A.(1)*;Laura, C.(1);David, R.D.L.C.(1);cristina, O.(1);Carmen, G.(2);Berta, D.L.H.(3);Francisco, L.(1);Ángeles, M.(1);carmen, Y.(1);Begoña, C.(1);Yago, G.L.(1);
(1)Digestive Medicine Department. Gastroenterology Section. IBD Unit. Hospital Universitario 12 de Octubre. Madrid. Spain., Digestive Medicine Department. Gastroenterology Section. IBD Unit. Hospital Universitario 12 de Octubre. Madrid. Spain., Madrid, Spain;(2)Pharmacology Department. Hospital Universitario 12 de Octubre. Madrid. Spain., Pharmacology Department. Hospital Universitario 12 de Octubre. Madrid. Spain., madrid, Spain;(3)Digestive Medicine Department. Hepatology Section. IBD Unit. Hospital Universitario 12 de Octubre. Madrid. Spain., Digestive Medicine Department. Hepatology Section. IBD Unit. Hospital Universitario 12 de Octubre. Madrid. Spain., madrid, Spain;
P1192: Use of a mobile application for monitoring and communicating with Inflammatory Bowel Disease patientsECCO'25Year: 2025
Authors: Lobato Matilla, M.E.(1)*;Chamorro de Vega, E.(1);Romero Jiménez, R.(1);Ferris Villanueva, M.(1);Menchén Viso, L.A.(2);Marín Jiménez, I.(2);Miranda Bautista, J.(2);Martinez Lozano, H.(2);Herranz Alonso, A.(1);Sanjurjo Sáez, M.(1);
(1)H.G.U. Gregorio Marañón, Pharmacy Department, Madrid, Spain;(2)H.G.U. Gregorio Marañón, Gastroenterology, Madrid, Spain;
P1194: Evaluating the Cost-Utility of Intestinal Resection Before Anti-Tumor Necrosis Factor Therapy for Strictures in Crohn's Disease in ChinaECCO'25Year: 2025
Authors: Tang, X.(1)*;Bai, X.(1);Yang, H.(1);Han, W.(2);
(1)Peking Union Medical College Hospital- Peking Union Medical College & Chinese Academy of Medical Sciences, Department of Gastroenterology, Beijing, China;(2)Institute of Basic Medical Sciences Chinese Academy of Medical Sciences,School of Basic Medicine Peking Union Medical College, Department of Epidemiology and Biostatistics, Beijing, China;
Knowles, S., et al., Quality of Life in Inflammatory Bowel Disease: A Systematic Review and Meta-analyses-Part II. Inflammatory bowel diseases, 2018. 24(5): p. 966-976.
Rieder, F., C. Fiocchi, and G. Rogler, Mechanisms, Management, and Treatment of Fibrosis in Patients With Inflammatory Bowel Diseases. Elsevier, 2017(2).
Mak, J.W.Y. and S.C. Ng, Epidemiology of fibrostenosing inflammatory bowel disease. Journal of digestive diseases, 2020. 21(6): p. 332-335.
Lin SN, M.R., Qian C, Bettenworth D, Wang J, Li J, Bruining DH, Jairath V, Feagan BG, Chen MH, Stenosis Therapy and Antifibrotic Research (STAR) Consortium; Rieder F. Development of antifibrotic therapy for stricturing Crohn's disease: lessons from randomized trials in other fibrotic diseases. . Physiol Rev, 2022.
P1195: Ecological momentary assessment of fatigue and depressive symptoms reveals significant daily variability in IBDECCO'25Year: 2025
Authors: Atanasova, K.(1)*;Bredensteiner , M.(1);Starrmann, A.(1);Ebert, M.(1);Thomann, A.(1);Lis, S.(2);Reindl, W.(1);
(1)Medical Faculty Mannheim- Heidelberg University, Department of Medicine II, Mannheim, Germany;(2)Central Institute of Mental Health- Medical Faculty Mannheim- Heidelberg University, Department of Clinical Psychology, Mannheim, Germany;
P1196: The impact of childhood adversity on the disease course in paediatric-onset IBD and immune-mediated inflammatory diseases: a population-based life-course study.ECCO'25Year: 2025
Authors: Malham, M.(1)*;Sejling , C.(2);Wilson, D.C.(1);Wewer, V.(3);Fox, M.(4);Rod, N.H.(5);
(1)Royal Hospital for Children and Young People, Department of Paediatric Gastroenterology and Nutrition, Edinburgh, United Kingdom;(2)University of Copenhagen, Section of Biostatistics- Department of Public Health, Copenhagen, Denmark;(3)Copenhagen University Hospital – Amager and Hvidovre-, Department of Paediatric and Adolescent Medicine, Copenhagen, Denmark;(4)Boston University School of Public Health, Departments of Epidemiology and Global Health, Boston, United States;(5)University of Copenhagen- Copenhagen, Copenhagen Health Complexity Center- Department of Public Health, Copenhagen, Denmark;
1: Schneider KM, Blank N, Alvarez Y, et al. The enteric nervous system relays psychological stress to intestinal inflammation. Cell. 2023;186(13):2823-2838.e20. doi:10.1016/j.cell.2023.05.001
2: Zhao J, Xue E, Zhou S, et al. Allostatic load increases the incidence and risk of adverse prognosis in inflammatory bowel disease. Aliment Pharmacol Ther. 2024;60(8):1062-1074. doi:10.1111/apt.18217
3: Rod NH, Bengtsson J, Budtz-Jørgensen E, et al. Trajectories of childhood adversity and mortality in early adulthood: a population-based cohort study. The Lancet. 2020;396(10249):489-497. doi:10.1016/S0140-6736(20)30621-8
P1197: Progression to colorectal cancer or high-grade dysplasia in individuals with inflammatory bowel disease and low-grade dysplasia: A cohort study of risk factors and incidenceECCO'25Year: 2025
Authors: Andersen, J.W.(1)*;Troelsen, F.S.(2);Erichsen, R.(2);Krogh, K.(3);Hart, A.(4);Dige, A.K.(3);
(1)Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark;(2)Aarhus University, Department of Clinical Epidemiology, Aarhus, Denmark;(3)Aarhus University Hospital, Department of Hepatology and Gastroenterology, Aarhus, Denmark;(4)St Mark's Hospital & Imperial College- London- UK, IBD-research, London, Denmark;
1. Olén O, Erichsen R, Sachs MC, et al. Colorectal cancer in Crohn’s disease: a Scandinavian population-based cohort study. Lancet Gastroenterol Hepatol. 2020;5(5):475-484. doi:10.1016/S2468-1253(20)30005-4
2. Olén O, Erichsen R, Sachs MC, et al. Colorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study. Lancet Lond Engl. 2020;395(10218):123-131. doi:10.1016/S0140-6736(19)32545-0
3. Fumery M, Dulai PS, Gupta S, et al. Incidence, Risk Factors, and Outcomes of Colorectal Cancer in Patients With Ulcerative Colitis With Low-Grade Dysplasia: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc. 2017;15(5):665-674.e5. doi:10.1016/j.cgh.2016.11.025
4. De Jong ME, Van Tilburg SB, Nissen LHC, et al. Long-term Risk of Advanced Neoplasia After Colonic Low-grade Dysplasia in Patients With Inflammatory Bowel Disease: A Nationwide Cohort Study. J Crohns Colitis. 2019;13(12):1485-1491. doi:10.1093/ecco-jcc/jjz114
P1198: Statin Use for Primary Prevention of Cardiovascular Disease and its Association with Risk of Incident Inflammatory Bowel Disease: A Population-Based Cohort StudyECCO'25Year: 2025
Authors: Faye, A.(1)*;Allin, K.(2);Juul Poulsen, G.(2);Jess, T.(2);
(1)NYU Grossman School of Medicine, Department of Medicine/Division of Gastroenterology & Hepatology, New York City, United States;(2)Aalborg University, Center for Molecular Prediction of Inflammatory Bowel Disease PREDICT, Copenhagen, Denmark;
P1199: Early life exposures predict childhood-onset IBD in a population-based cohortECCO'25Year: 2025
Authors: Agrawal, M.(1,2)*;Hansen, A.V.(2);Colombel, J.F.(3);Allin, K.H.(2,4);Jess, T.(2,4);
(1)Icahn School of Medicine at Mount Sinai, The Dr. Henry D. Janowitz Division of Gastroenterology-, New York, United States;(2)Center for Molecular Prediction of Inflammatory Bowel Disease PREDICT- Aalborg University, Department of Clinical Medicine, Copenhagen, Denmark;(3)Icahn School of Medicine at Mount Sinai, Gastroenterology, New York, United States;(4)Aalborg University Hospital, Department of Gastroenterology & Hepatology, Aalborg, Denmark;
P1200: Increasing rate of hospitalization for inflammatory bowel disease is an age-related effect: A Canadian population-based studyECCO'25Year: 2025
Authors: Goodwin, S.(1)*;Wilk, P.(2,3);Yuan, Y.(1,4);Haan, M.(5);Jairath, V.(2,4,6);
(1)Lawson Health Research Institute, Medicine, London, Canada;(2)Western University, Epidemiology & Biostatistics, London, Canada;(3)Maastricht University, Epidemiology, Maastricht, The Netherlands;(4)Western University, Medicine, London, Canada;(5)Western University, Sociology, London, Canada;(6)Alimentiv Inc., Gastroenterology, London, Canada;
1. Buie et al. 2023. Doi: 10.1093/ibd/izad020
P1201: Pre- and postnatal metal exposures impact Crohn’s Disease risk and intestinal inflammation in an analysis of deciduous teethECCO'25Year: 2025
Authors: Tinoco da Silva Torres, J.(1,2,3)*;Midya, V.(4);Picker, M.(5);Martinez, M.(4);Moreira-Barbosa, C.(6);Kim, T.(4);H Allin, K.(7,8);Jess, T.(7,8);Saraiva, S.(2);Gouveia, C.(2);Talamini, R.(9);Brand, E.(10);Oldenburg, B.(10);Amil Dias, J.(11);Amorim, R.(12);Trindade, E.(12);Colombel, J.F.(13);Peter, I.(5);Arora, M.(4);Agrawal, M.(7,13);
(1)Hospital da Luz, Division of Gastroenterology, Lisboa, Portugal;(2)Hospital Beatriz Ângelo, Division of Gastroenterology, Loures, Portugal;(3)Universidade de Lisboa, Faculdade de Medicina, Lisboa, Portugal;(4)Icahn School of Medicine at Mount Sinai, Department of Environmental Medicine and Climate Science, New York, United States;(5)Icahn School of Medicine at Mount Sinai, Department of Genetics and Genomic Sciences, New York, United States;(6)Hospital da Luz Learning Health, Luz Saúde, Lisboa, Portugal;(7)Aalborg University, Department of Clinical Medicine, Copenhagen, Denmark;(8)Aalborg University Hospital, Department of Gastroenterology and Hepatology, Aalborg, Denmark;(9)Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil;(10)University Medical Center Utrecht, Department of Gastroenterology and Hepatology, Utrecht, The Netherlands;(11)Hospital Lusíadas, Division of Gastroenterology, Porto, Portugal;(12)Centro Hospitalar Universitário São João, Department of Pediatrics, Porto, Portugal;(13)Icahn School of Medicine at Mount Sinai, Division of Gastroenterology, New York, United States;
P1202: Metabolic-dysfunction associated liver disease in patient with Inflammatory Bowel Disease: Is obesity the major driver of disease progression?ECCO'25Year: 2025
Authors: Bracciamà , E.(1);Di Giorgio , F.M.(1);Melatti , P.(1);Amato , L.M.(1);Salerno , I.A.(1);Ajovalasit , R.(1);Di Prima , L.(1);Scalia , S.(1);Gambadauro , D.(1);Pennisi , G.(1);Petta , S.(1);Cappello , M.(1)*;
(1)Section of Gastroenterology and Hepatology- University of Palermo- Italy, Department of Health Promotion- Mother and Child Care- Internal Medicine and Medical Specialties PROMISE, Palermo, Italy;
P1203: Spatial mapping and geographic variation of inflammatory bowel disease in Canada: A population-based study using Statistics Canada dataECCO'25Year: 2025
Authors: Goodwin, S.(1)*;Haan, M.(2);Yuan, Y.(1,3);Wilk, P.(4,5);Jairath, V.(3,4,6);
(1)Lawson Health Research Institute, Medicine, London, Canada;(2)Western University, Sociology, London, Canada;(3)Western University, Medicine, London, Canada;(4)Western University, Epidemiology & Biostatistics, London, Canada;(5)Maastricht University, Epidemiology, Maastricht, The Netherlands;(6)Alimentiv Inc., Gastroenterology, London, Canada;
1. Ng et al., 2017. Doi: 10.1016/s0140-6736(17)32448-0
2. Coward et al., 2023. Doi: 10.1093/jcag/gwad004
P1204: Childhood EBV infection is protective against IBD, while adulthood EBV infection is not: a population-based cohort studyECCO'25Year: 2025
Authors: Agrawal, M.(1,2)*;Allin, K.H.(2,3);Hansen, A.V.(2);Colombel, J.F.(1);Jess, T.(2,3);
(1)Icahn School of Medicine at Mount Sinai, Gastroenterology, New York, United States;(2)Center for Molecular Prediction of Inflammatory Bowel Disease PREDICT- Aalborg University, Department of Clinical Medicine, Copenhagen, Denmark;(3)Aalborg University Hospital, Department of Gastroenterology & Hepatology, Aalborg, Denmark;
P1205: Long-term treatment patterns, dose escalation, and steroid use among patients with moderate-to-severe ulcerative colitis using advanced therapies: >3 years of continuous follow up using IQVIA PharMetrics Plus databaseECCO'25Year: 2025
Authors: Dulai, P.(1)*;Rabbat, C.(2);Nason, I.(3);Ng, S.(4);Yang, Y.(5);Hua, Y.(6);Kirson, N.(6);Fine, J.(7);
(1)Northwestern University, Feinberg School of Medicine, Chicago, United States;(2)Abivax SA, Medical Affairs, Boston, United States;(3)Analysis Group- Inc., Health Economics and Outcomes Research, New York, United States;(4)Analysis Group- Inc., Health Economics and Outcomes Research, Los Angeles, United States;(5)Analysis Group- Inc., Health Economics and Outcomes Research, Menlo Park, United States;(6)Analysis Group- Inc., Health Economics and Outcomes Research, Boston, United States;(7)Abivax SA, Real World Evidence, Boston, United States;
1.Afzali A, Lukanova R, Hennessy F, et al. Unmet needs in real-world advanced therapy-naive and -experienced patients with moderately to severely active ulcerative colitis in the United States. Adv Ther. 2023;40(10):4321-4338.
2.Lee SD, LaPensee K, Betts KA, et al. S740 Rates of treatment failure among patients with ulcerative colitis treated with first-line advanced therapies. Am J Gastroenterol. 2021;116:S340
P1206: The Incidence and Disease Course of Perianal Disease in Paediatric-Onset Crohn's Disease: A Danish Nationwide Cohort Study Covering 1980-2022ECCO'25Year: 2025
Authors: Ström, A.(1);Jansson, S.(1);Wewer, M.D.(2);Burisch, J.(2);Malham, M.(3)*;Wewer, V.(4);
(1)Copenhagen University Hospital - Amager and Hvidovre Hospital, Department of Paediatric and Adolescent Medicine, Copenhagen, Denmark;(2)Copenhagen University Hospital - Amager and Hvidovre, Gastrounit- Medical Division, Copenhagen, Denmark;(3)Royal Hospital for Children and Young People, Department of Paediatric Gastroenterology and Nutrition, Edinburgh, United Kingdom;(4)Copenhagen University Hospital - Amager and Hvidovre, Department of Paediatric and Adolescent Medicine, Copenhagen, Denmark; The Copenhagen IBD Center
P1207: Therapy goals and Quality of Life among older patients with Inflammatory Bowel Disease: results of an international EFCCA surveyECCO'25Year: 2025
Authors: Fons, A.(1,2)*;Girardi, P.(3,4);Savini, C.(5);Maljaars, J.(1);Haaf, I.(4);Avedano*, L.(4);Asscher*, V.(1,6);
(1)Leiden University Medical Center, Department of Gastroenterology and Hepatology, Leiden, The Netherlands;(2)Spaarne Gasthuis, Department of Geriatric Medicine, Haarlem, The Netherlands;(3)University Ca’ Foscari of Venice, Department of Environmental Science- Informatics and Statistics, Venice, Italy;(4)European Federation of Crohn's and Ulcerative Colitis Associations, efcca, Brussels, Belgium;(5)Patients in Science, Medical writing and consulting, Valencia, Spain;(6)HagaZiekenhuis, Department of Gastroenterology and Hepatology, The Hague, The Netherlands;
P1209: Temporal trends in surgery and hospitalization rates for crohn's disease in Brazil: A population-based studyECCO'25Year: 2025
Authors: Dos Reis Guerra, J.A.(1)*;Magro, D.O.(2);Coy, C.S.R.(2);Valverde, D.A.(3);Oliveira, E.S.(4);Quaresma, A.B.(5,6);Kotze, P.G.(6,7);
(1)Catholic University of Paraná, Colorectal Surgery Unit, Curitiba, Brazil;(2)University of Campinas UNICAMP, Colorectal Surgery Unit, Campinas, Brazil;(3)Techtrials Healthcare, Data Science, Vinhedo, Brazil;(4)University of Campinas UNICAMP, Department of Internal Medicine, Campinas, Brazil;(5)Universidade do Oeste de Santa Catarina- UNOESC, IBD outpatient clinic, Joaçaba, Brazil;(6)Catholic University of Paraná, Health Sciences Postgraduate Program, Curitiba, Brazil;(7)Catholic University of Paraná, IBD outpatient Clinics, Curitiba, Brazil;
Mowat C, Cole A, Windsor A, et al. Guidelines for the management of inflammatory bowel disease in adults. Gut. 2011;60(5):571-607. doi:10.1136/gut.2010.2241542.
Quaresma AB, Kaplan GG, Kotze PG. The globalization of inflammatory bowel disease: the incidence and prevalence of inflammatory bowel disease in Brazil. Curr Opin Gastroenterol. 2019;35(4):259-264. doi:10.1097/MOG.00000000000005343.
Quaresma AB, Damiao AOMC, Coy CSR, et al. Temporal trends in the epidemiology of inflammatory bowel diseases in the public healthcare system in Brazil: A large population-based study. Lancet Reg Health Am. 2022;13:100298. Published 2022 Jun 9. doi:10.1016/j.lana.2022.1002984.
Palacio FGM, de Souza LMP, Moreira JPL, Luiz RR, de Souza HSP, Zaltman C. Hospitalization and surgery rates in patients with inflammatory bowel disease in Brazil: a time-trend analysis. BMC Gastroenterol. 2021;21(1):192. Published 2021 Apr 27. doi:10.1186/s12876-021-01781-x