¹University Hospital Estaing, Gastroenterology Department, Clermont-Ferrand, France, ²UMR 1071 Inserm/Université d’Auvergne; USC-INRA 2018, Microbes, Intestine, Inflammation and Susceptibility of the host, Clermont-Ferrand, France, ³University Hospital G. Montpied, Biochemistry laboratory, Clermont-Ferrand, France, ⁴GM – Clermont-Ferrand University and Medical Centre, Biostatistics Unit, Clermont-Ferrand, France

¹Academic Medical Centre (AMC), Radiology, Amsterdam, Netherlands, ²OLVG, Radiology, Amsterdam, Netherlands, ³Academic Medical Centre (AMC), Gastroenterology, Amsterdam, Netherlands

Kyoto Prefectural University of Medicine, Molecular Gastroenterology and Hepatology, Kyoto, Japan

¹Jagiellonian University Medical College, Department of Integrated Dentistry, Kraków, Poland, ²Jagiellonian University Medical College, Department of Gastroenterology and Hepatology, Kraków, Poland, ³University of Duisburg-Essen, Department of Gynaecology and Obstetrics, Essen, Germany, ⁴Jagiellonian University Medical College, Department of Food Chemistry and Nutrition, Kraków, Poland

Sapienza University, Paediatric Gastroenterology and Liver Unit, Rome, Italy

¹Hvidovre University Hospital, Dept. of Medical Gastroenterology, Hvidovre, Denmark, ²Køge University Hospital, Medical Department, Køge-4600, Denmark, ³Hvidovre University Hospital, Clinical Physiology and Nuclear Medicine, Hvidovre, Denmark, ⁴Køge University Hospital, Clinical Biochemistry, Køge, Denmark, ⁵Sorbonne University - UPMC, Clinical Biochemistry, Paris, France, ⁶Gentofte University Hospital, Research Unit, Gentofte, Denmark, ⁷Køge University Hospital, Medical Department, Køge, Denmark, ⁸University of Copenhagen, Department of Medical Physiology, Copenhagen, Denmark

¹Hospital Universitario de La Princesa, IIS-IP and CIBERehd, Gastroenterology Unit, Madrid, Spain, ²Hospital Universitario de Fuenlabrada, Gastroenterology Unit, Madrid, Spain, ³Hospital de Donostia, Instituto Biodonostia, UPV/EHU and CIBEREHD, Gastroenterology Unit, Guipuzcoa, Spain, ⁴Hospital Galdakao, Gastroenterology Unit, Vizcaya, Spain, ⁵Hospital Clínico Universitario San Carlos and IdISSC, Gastroenterology Unit, Madrid, Spain, ⁶Hospital Gregorio Marañón and IiSGM, Gastroenterology Unit, Madrid, Spain

University of Oulu and Northern Finland Laboratory Centre Nordlab, Oulu, Finland

¹Kyushu University, Medicine and Clinical Science, Fukuoka, Japan, ²Iwate Medical University, Internal Medicine, Morioka, Japan, ³University of Miyazaki, Gastroenterology and Hepatology, Miyazaki, Japan, ⁴University of Ryukyus, Endoscopy, Okinawa, Japan, ⁵Fukuoka University Chikushi Hospital, Gastroenterology, Chikushino, Japan, ⁶Aizu Medical Centre, Fukushima Medical University, Coloproctology, Fukushima, Japan, ⁷Osaka City University, Gastroenterology, Osaka, Japan, ⁸Osaka Medical College, Second Department of Internal Medicine, Takatsuki, Japan, ⁹University of Miyazaki, Circulatory and Body Fluid Regulation, Miyazaki, Japan, ¹⁰Nagoya University Graduate School of Medicine, Gastroenterology and Hepatology, Nagoya, Japan, ¹¹Toho University, Sakura Medical Centre, Internal Medicine, Chiba, Japan

¹Peking Union Medical College Hospital, Gastroenterology, Beijing, China, ²Peking Union Medical College Hospital, Rheumatology and Clinical Immunology, Beijing, China

¹King’s College Hospital NHS Foundation Trust, Gastroenterology, London, United Kingdom, ²King’s College London, Department of Psychological Medicine, London, United Kingdom

¹Daehang Hospital, Gastroenterology, Seoul, South Korea, ²Soonchunhyang University Hospital, Gastroenterology, Gumi-si, South Korea, ³Daehang Hospital, Surgery, Seoul, South Korea

Yokkaichi Hazu Medical Centre, Inflammatory Bowel Disease Centre, Yokkaichi, Japan

¹University Hospital Virgen Macarena, Gastroenterology and Hepatology Department, Seville, Spain, ²University Hospital Virgen Macarena, Pathology Department, Seville, Spain

¹Peking Union Medical College Hospital, Department of Gastroenterology, Beijing, China, ²Peking Union Medical College Hospital, Beijing, China

¹Icahn School of Medicine at Mount Sinai, Department of Medicine, New York, New York, United States, ²Hospital Garcia de Orta, Gastroenterology, Almada, Portugal

Korea University College of Medicine, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul, South Korea

¹Hospital university of Sahloul, Gastroenterology, Sousse, Tunisia, ²Hospital university of Sahloul, Sousse, Tunisia, ³Hospital university of Sahloul, surgery, Sousse, Tunisia

¹St Mark’s Hospital, Colorectal Surgery & IBD Unit, London, United Kingdom, ²St Mark’s Hospital, London, United Kingdom, ³Imperial, London, United Kingdom, ⁴St Mark’s Hospital, London, United Kingdom

1Massachusetts General Hospital, Department of Gastroenterology, Boston, Massachusetts, United States, 2University Medical Centre Groningen, Department of Gastroenterology and Hepatology, Groningen, Netherlands, 3University Medical Centre Groningen, Department of Epidemiology, Groningen, Netherlands

Abstract has been withdrawn.