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P097: MicroRNA23a is overexpressed in the colonic epithelium in Crohn’s diseaseECCO '16 Amsterdam
Year: 2016
Authors:

R. Felwick*1, G. Dingley1, T. Sanchez-Elsner1, J. Collins1, F. Cummings2

1University of Southampton, Clinical and Experimental Sciences, Southampton, United Kingdom, 2University Hospital Southampton, Gastroenterology, Southampton, United Kingdom

P098: Anti-fibrotic effects of a novel small compound that promotes the nuclear translocation of YB-1 in a mouse model of colorectal fibrosisECCO '16 Amsterdam
Year: 2016
Authors:

J. Imai*1, K. Hozumi2, Y. Inagaki3, T. Mine1

1Tokai university School of Medicine, Gastroenterology, Isehara, Japan, 2Tokai university School of Medicine, Immunology, Isehara, Japan, 3Tokai university School of Medicine, Regenerative Medicine, Isehara, Japan

P099: Inhibitory effect of 6-aminopyridin-3-ol analogues on TNF-α-induced monocyte-colon epithelial cell adhesion and TNBS-induced rat colitisECCO '16 Amsterdam
Year: 2016
Authors:

B.-S. Jeong*1, S. Banskota1, P. Grung1, T.-g. Nam2, J.-A. Kim1

1Yeungnam University, College of Pharmacy, Gyeongsan, South Korea, 2Hanyang University, College of Pharmacy, Ansan, South Korea

P100: Effects of a narrow spectrum kinase inhibitor and selective kinase inhibitors on the intestinal pro-inflammatory immune response in ulcerative colitisECCO '16 Amsterdam
Year: 2016
Authors:

M. R. Foster*1, P. Biancheri2, Y. Solanke1, S. Sirohi1, M. C. Fyfe1, A. Rowley1, T. T. MacDonald2, E. Wood3, S. Webber1, C. A. Walshe1

1Topivert Pharma Ltd, London, United Kingdom, 2Barts and the London, School of medicine and dentistry, London, United Kingdom, 3Homerton University Hospital, Academic Department of Medical and Surgical Gastroenterology, London, United Kingdom

P101: Functional translation of IBD-associated genetic variation in patient-derived intestinal epithelial cellsECCO '16 Amsterdam
Year: 2016
Authors:

W. Vanhove*1, K. Nys1, I. Arijs1, I. Cleynen2, G. Van Assche1, M. Ferrante1, S. Vermeire1

1KU Leuven, Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Clinical and Experimental Medicine, Leuven, Belgium, 2KU Leuven, Department of Human Genetics, Leuven, Belgium

P102: α-Defensins(αDef) 1-3 are specific plasmatic markers for Crohn’s disease (CD) at diagnosis and tissue α-Def 5 methylation is a pathogenic mechanism for αDef-5 down regulation in CD.ECCO '16 Amsterdam
Year: 2016
Authors:

E. Cerrillo1, I. Moret-Tatay2,3, M. Iborra1,2, E. Sáez-González1, E. Busó4, D. Ramos5, L. Tortosa1, P. Nos1,3, B. Beltrán*1,3

1Hospital Universitari La Fe, Gastroenterology, Valencia, Spain, 2Ciberehd, Gastroenterology, Valencia, Spain, 3IIS Hospital La Fe, Gastroenterology, Valencia, Spain, 4School of Medicine. Valencia University, Central Unit of Medical Research, Valencia, Spain, 5Hospital Universitari La Fe, Pathology, Valencia, Spain

P103: Selective M1 macrophage polarisation in Crohn’s disease in comparison to intestinal tuberculosis: a novel observationECCO '16 Amsterdam
Year: 2016
Authors:

P. Das1, S. Pilli2, T. Kumar1, R. Rampal2, I. A. Khan2, A.K. Singh2, D. Kumar3, V. Ahuja*2

1All India Institute of Medical Sciences, Pathology, New Delhi, India, 2All India Institute of Medical Sciences, Gastroenterology, New Delhi, India, 3International Centre for Genetic Engineering and Biotechnology, Mammalian Biology, New Delhi, India

P104: Risk factors associated with the negativisation of anti-HBs antibodies in inflammatory bowel disease patientsECCO '16 Amsterdam
Year: 2016
Authors:

A. C. Marín*1, M. Chaparro1, M. Ramas1, R. R. Ribot1, P. M. Linares1, J. R. Villagrasa2, D. Bernardo1, J. P. Gisbert1

1Hospital Universitario de La Princesa, IIS-IP and CIBERehd, Gastroenterology Unit, Madrid, Spain, 2Hospital Universitario de La Princesa and IIS-IP , Preventive medicine unit, Madrid, Spain

P105: Inhibition of cytokine release from HT-29 cells and ulcerative colitis biopsies is potentiated by combination of selective kinase inhibitors, and such effects are mimicked by TOP1210, a narrow spectrum kinase inhibitor ECCO '16 Amsterdam
Year: 2016
Authors:

M. R. Foster*1, P. Biancheri2, S. Sirohi1, Y. Solanke1, M. C. Fyfe1, A. Rowley1, T. T. MacDonald2, E. Wood3, S. Webber1, C. A. Walshe1

1Topivert Pharma Ltd, London, United Kingdom, 2Barts and the London, School of Medicine and Dentistry, London, United Kingdom, 3Homerton University Hospital, Academic Department of Medical and Surgical Gastroenterology, London, United Kingdom

P106: Maintenance treatment with granulocyte/monocyte adsorption in patients with inflammatory bowel disease and an initial response to treatment: a Swedish long-term prospective registry studyECCO '16 Amsterdam
Year: 2016
Authors:

A. Lindberg1, 2, S. Lindgren3, M. Lördal4, S. Nilsson5, H. Svensson6, P. Karlen*1

1Department of Clinical Science, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden, Stockholm, Sweden, 2Karolinska Institutet, Danderyds hospital, Department of Clinical Science, Stockholm, Sweden, 3Department of Gastroenterology, University Hospital Skane, Sweden, Malmö, Sweden, 4Department of Medicine, Division of Gastroenterology and Hepathology at Karolinska Institutet, Huddinge, Sweden, Stockholm, Sweden, 5Department of Medicine, Kristianstad Hospital, Kristianstad, Sweden,, Kristianstad, Sweden, 6Departments of Internal Medicine, Vrinnevi Hospital, Norrköping, Sweden, Norrköping, Sweden

P107: IL-34 and IL-36 family expressing cytotoxic T-cells and plasmacytoid dendritic cells are increased 
in patients with active inflammatory bowel diseaseECCO '16 Amsterdam
Year: 2016
Authors:

G. Fonseca Camarillo*1, E. Iturriaga Goyon2, J. Furuzawa Carballeda3, J. Yamamoto Furusho2

1Instituto Nacional de Ciencias Médicas y Nutrición, Inflammatory Bowel Disease Clinic, Department of Gastroenterology, Mexico, Mexico, 2Instituto Nacional de Ciencias Médicas y Nutrición, Inflammatory Bowel Disease Clinic. Department of Gastroenterology, Mexico, Mexico, 3Instituto Nacional de Ciencias Médicas y Nutrición, Department of Immunology and Rheumatology, Mexico, Mexico

P108: Cytokine levels differ during pregnancy amongst women with ulcerative colitis and Crohn’s diseaseECCO '16 Amsterdam
Year: 2016
Authors:

V. W. Huang*1, N. Hotte2, L. Ambrosio1, K. Smith2, J. Bal1, R. Foshaug1, K. I. Kroeker1, B. Halloran1, L. Dieleman1, R. N. Fedorak1, K. Madsen2

1University of Alberta, Gastroenterology, Edmonton, Canada, 2University of Alberta, Edmonton, Canada

P109: Effect of dysbiosis on the growth and colitis susceptibility in DSS colitis modelECCO '16 Amsterdam
Year: 2016
Authors:

C. S. Eun*, D. S. Han, A. R. Lee, Y. R. Lee

Hanyang University Guri Hospital, Gastroenterology, Guri, South Korea

P110: Cigarette smoke modulates the effect of dextran sulfate sodium–induced colitis on a subpopulation of T-cells in blood and colon in miceECCO '16 Amsterdam
Year: 2016
Authors:

J. Daniluk*1, U. Daniluk2, M. Rusak3, J. Reszec4, M. Dabrowska3, A. Dabrowski1

1Medical University of Bialystok, Department of Gastroenterology and Internal Medicine, Bialystok, Poland, 2Medical University of Bialystok, Department of Paediatrics, Gastroenterology and Allergology, Bialystok, Poland, 3Medical University of Bialystok, Department of Haematological Diagnostics, Bialystok, Poland, 4Medical University of Bialystok, Department of Medical Pathomorphology, Bialystok, Poland

P111: Differences in therapies and intestinal resection rates between adult and elderly onset Crohn’s diseaseECCO '16 Amsterdam
Year: 2016
Authors:

C. Alexakis*1, S. Saxena2, V. Chhaya1, E. Cecil2, R. Pollok1

1St George’s Hospital, Gastroenterology, London, United Kingdom, 2Department of Primary Care and Public Health, Imperial College, London, United Kingdom

P112: Validation of the simplified Geboes score for ulcerative colitisECCO '16 Amsterdam
Year: 2016
Authors:

A. Jauregui-Amezaga*1, Y. Das2, T. Lobatón3, B. Lemmens2, T. Bessissow4, M. Ferrante1, G. Van Assche1, R. Bisschops1, K. Geboes2, G. De Hertogh2, S. Vermeire1

1University Hospitals Leuven, Gastroenterology, Leuven, Belgium, 2University Hospitals Leuven, Pathology, Leuven, Belgium, 3Hospital Universitari Germans Trias i Pujol, Gastroenterology, Badalona, Spain, 4Mc Gill University Health Centre, Gastroenterology, Montreal, Canada

P113: Quality of life in paediatric Crohn’s disease: data from the Imagekids studyECCO '16 Amsterdam
Year: 2016
Authors:

V. M. Navas-López*1, 2, J. Martín-de-Carpi3, A. Grant4, T. D. Walters5, F. Ruemmele6, D. Mack7, M. Sladek8, R. Shamir9, R. Shaoul10, S. Saeed11, R. K. Russell12, R. Cytter-Kuint13, A. Griffiths14, D. Turner13, A. Otley4

1Paediatric Gastroenterology and Nutrition Unit, Hospital Materno Infantil, Málaga, Spain, 2IBIMA, Biomedical Institute of Málaga, Málaga, Spain, 3Unit for the Comprehensive Care of Paediatric Inflammatory Bowel Disease, Department of Paediatric Gastroenterology, Hepatology and Nutrition, Barcelona, Spain, 4IWK Health Centre, Halifax, Nova Scotia, Canada, 5Hospital for Sick Children, Toronto, Ontario, Canada, 6Hôpital Necker-Enfants Malades, Paris, France, 7Children’s Hospital of Eastern Ontario, Ottawa, Ontario, Canada, 8Jagiellonian University Medical College, Krakow, Poland, 9Schneider Children’s Medical Centre, Petach Tikvah, Israel, 10Rambam Health Care Campus, Haifa, Israel, 11Cincinnati Children’s Hospital Medical Centre, Cincinnati, Ohio,United States, 12Royal Hospital for Children, Glasgow, United Kingdom, 13Institute of Paediatric Gastroenterology, Shaare Zedek Medical Centre, The Hebrew University of Jerusalem, Jerusalem, Israel, 14Hospital for Sick Children, Toronto, Canada

P114: Predictors of clinical response during adalimumab therapy in Crohn’s disease patients: a German non-interventional studyECCO '16 Amsterdam
Year: 2016
Authors:

I. Blumenstein*1, R. Atreya2, G. Greger3, B. Bokemeyer4, P. Nurwakagari3, M. F. Neurath2, B. Wittig3

1Goethe-University Frankfurt, Gastroenterology, Frankfurt am Main, Germany, 2University Erlangen, Erlangen, Germany, 3AbbVie Deutschland GmbH & Co.KG, Wiesbaden, Germany, 4Gastroenterology Practice, Minden, Germany

P115: Standardising assessment and documentation of pouchoscopyECCO '16 Amsterdam
Year: 2016
Authors:

V. A. van der Ploeg1, Y. Maeda*1, O. D. Faiz1, A. L. Hart2, S. K. Clark1

1St Mark’s Hospital, Department of Surgery, Harrow, United Kingdom, 2St Mark’s Hospital, Department of Gastroenterology, Harrow, United Kingdom

P116: Usefulness of consecutive faecal calprotectin measurements to predict relapse in inflammatory bowel disease patients under maintenance treatment with anti-TNF therapy: a prospective longitudinal cohort studyECCO '16 Amsterdam
Year: 2016
Authors:

R. Ferreiro*, M. Barreiro-de Acosta, A. Lorenzo, J. E. Dominguez-Munoz

University Hospital Santiago de Compostela, Gastroenterology, Santiago, Spain