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P017: Periostin aggravates the development of colitis-associated colon cancer in miceECCO '16 Amsterdam
Year: 2016
Authors:

S.-J. Koh*1, J. W. Kim1, B. G. Kim1, K. L. Lee1, J. S. Kim2

1Seoul National University Boramae Hospital, Seoul National University College of Medicine, Internal Medicine, Seoul, South Korea, 2Seoul National University College of Medicine, Internal Medicine and Liver Research Institute, Seoul, South Korea

P018: Biologic functions between non-affected and affected margins of ileum samples from Crohn’s disease patients who will develop post-surgical recurrence.ECCO '16 Amsterdam
Year: 2016
Authors:

V. Loren*1, 2, A. Garcia-Jaraquemada1, A. Aterido3, F. Kamberovic1, A. Julià3, Y. Zabana4, A. Alonso3, M. Mañosa2, 5, S. Marsal3, E. Domènech2, 5, E. Cabré2, 5, J. Manyé2, 6

1Health Sciences Research Institute of the ‘Germans Trias i Pujol’ Foundation (IGTP), Inflammatory Bowel Disease Unit, Badalona, Spain, 2Centro de Investigación Biomédica en Red (CIBER), Madrid, Spain, 3Institute for research in Biomedicine, Rheumatology Research Group, Barcelona, Spain, 4Mútua de Terrassa Hospital, Terrassa, Spain, 5Germans Trias i Pujol Hospital, Inflammatory Bowel Disease Unit, Badalona, Spain, 6Health Sciences Research Institute of the ‘Germans Trias i Pujol’ Foundation (IGTP), Inflammatory Bowel Disease Unit, Badalona, Spain

P019: Informing ulcerative colitis pathophysiology and outcomes through metabolic pofilingECCO '16 Amsterdam
Year: 2016
Authors:

S. Fong*1, C. Le Roy2, J. Sanderson1, S. Claus2

1Guy’s and St Thomas’ NHS Foundation Trust, IBD Centre, London, United Kingdom, 2University of Reading, Department of Food and Nutritional Sciences, Reading, United Kingdom

P020: The efficacy of tofacitinib and a selective Janus kinase 1 inhibitor in dextran sulphate sodium colitis modelsECCO '16 Amsterdam
Year: 2016
Authors:

L. De Vries*1, 2, F. van Leeuwen-Hilbers2, P. van Hamersveld2, V. Ludbrook3, G. D’Haens1, W. De Jonge2

1Academic Medical Centre (AMC), Gastroenterology & Hepatology, Amsterdam, Netherlands, 2Academic Medical Centre (AMC), Tytgat Institute for Liver and Intestinal Research, Amsterdam, Netherlands, 3GlaxoSmithKline, Immuno-Inflammation Therapy Area, Stevenage, United Kingdom

P021: Inflammatory monocytes are key regulators of colonic inflammation in murine and human IBDECCO '16 Amsterdam
Year: 2016
Authors:

G.-R. Jones*1, P. Cook2, A. MacDonald2, T. Fenton2, A. Kelly2, M. Travis2, S. Campbell3

1University of Edinburgh, Gastroenterology, Edinburgh, United Kingdom, 2University of Manchester, Department of Immunology, Manchester, United Kingdom, 3University of Manchester / Manchester Royal Infirmary, Department of Gastroenterology, Jean Mcfarlane Building; School for Nursing, Manchester, United Kingdom

P022: Parthenolide enhances the efficacy of anti-tumour effect of balsalazide in human colon cancer cells and colitis-associated colorectal cancer by blockade of NF-kB activationECCO '16 Amsterdam
Year: 2016
Authors:

G. S. Seo1, S.-L. Kim2, S. W. Kim*2

1Wonkwang university college of medicine, Internal medicine, Iksan, South Korea, 2Chonbuk national university hospital, Internal medicine, Jeonju, South Korea

P023: Development of methods to investigate effects of narrow spectrum kinase inhibitors on cellular phosphorylation of kinase substratesECCO '16 Amsterdam
Year: 2016
Authors:

S. Sirohi*, M. Foster, M. Fyfe, Y. Solanke, S. Webber, C. Walshe

Topivert Pharma, London, United Kingdom

P024: Therapeutic potential of the human amniotic fluid mesenchymal stem cells/stroma cells secreted molecules in a mice model of colitisECCO '16 Amsterdam
Year: 2016
Authors:

M. Gazouli*1, E. Legaki1, M. Roubelakis1, A. Lazaris2, G. Karamanolis3, E. Marinos1, G. Theodoropoulos4

1School of Medicine, University of Athens, Biology, Athens, Greece, 2School of Medicine, University of Athens, Pathology, Athens, Greece, 3School of Medicine, University of Athens, Gastroenterology, Athens, Greece, 4School of Medicine, University of Athens, Surgery, Athens, Greece

P025: Tonsil-derived mesenchymal stem cell ameliorate intestinal fibrosis in chronic murine colitis modelECCO '16 Amsterdam
Year: 2016
Authors:

E. M. Song*1, S.-A. Jung1, S.-E. Kim1, K. E. Lee1, J. Y. Chang1, H. M. Son1, M. S. Ryu1, Y. H. Joo1, C. H. Tae1, C. M. Moon1, H.-K. Jung1, K.-N. Shim1, I. H. Jo2, Y. S. Yu2

1Ewha Woman’s University School of Medicine, Department of Internal Medicine, Ewha Medical Research Institute, Seoul, South Korea, 2Ewha Woman’ University School of Medicine, Department of Molecular Medicine, Ewha Medical Research Institute, Seoul, South Korea

P026: Characterisation of mucosal CD4+ T-cells in peripheral blood of healthy controls and paediatric inflammatory bowel disease patientsECCO '16 Amsterdam
Year: 2016
Authors:

M. Joosse*1, C. Menckeberg1, L. de Ruiter1, H. Raatgeep1, L. van Berkel1, F. Muskens2, R. Hendriks2, R. Hoogenboezem3, T. Cupedo3, L. de Ridder4, H. Escher4, S. Veenbergen1, J. Samsom1

1Erasmus MC, Laboratory of Paediatrics, division Gastroenterology and Nutrition, Rotterdam, Netherlands, 2Erasmus MC, Department of Pulmonary Medicine, Rotterdam, Netherlands, 3Erasmus MC, Department of Haematology, Rotterdam, Netherlands, 4Erasmus MC, Department of Paediatric Gastroenterology, Rotterdam, Netherlands

P027: Characterisation of human intestinal dendritic cells and macrophages through the lower gastrointestinal tract.ECCO '16 Amsterdam
Year: 2016
Authors:

D. Bernardo*, A. C. Marín, P. M. Linares, M. Jiménez, M. Chaparro, J. P. Gisbert

Hospital Universitario de La Princesa, IIS-IP and CIBERehd, Gastroenterology Unit, Madrid, Spain

P028: Inflammatory bowel disease is associated with cytoskeleton rearrangement in the epithelial cellsECCO '16 Amsterdam
Year: 2016
Authors:

A. Portyanko1, P. Perevoschikov1, K. Ruksha1, J. Gorgun*2

1Belarusian State Medical University, Department of Pathology, Minsk, Belarus, 2Belarusian Medical Academy of Postgraduate Education, Department of Gastroenterology and Nutrition, Minsk, Belarus

P029: Intestinal mesenchymal-specific IKK2 promotes initiation of colitis and colitis-associated cancerECCO '16 Amsterdam
Year: 2016
Authors:

V. Koliaraki*1, M. Pasparakis2, G. Kollias1, 3

1BSRC "Alexander Fleming", Vari, Greece, 2University of Cologne, Institute of Genetics, Cologne, Germany, 3University of Athens, Department of Physiology, Athens, Greece

P030: Development of small bowel tissue phantom for microultrasound 
investigationECCO '16 Amsterdam
Year: 2016
Authors:

T. Anbarasan*1, C. E. M. Démoré1, H. Lay2, M. R. S. Sunoqrot1, R. Poltarjonoks1, S. Cochran2, B. F. Cox1

1University of Dundee, Dundee, United Kingdom, 2University of Glasgow, Glasgow, United Kingdom

P031: STAT6 deficiency alters macrophage polarisation and promotes fibrosis in a murine model of chronic inflammationECCO '16 Amsterdam
Year: 2016
Authors:

P. Salvador*1, D. Ortiz-Masiá1, D. C. Macias-Ceja1, 2, J. Cosín-Roger1, L. Gisbert-Ferrándiz1, C. Hernández2, S. Calatayud1, M. D. Barrachina-Sancho1

1University of Valencia, Valencia, Spain, 2Fisabio Hospital Peset, Valencia, Spain

P032: IFN-γ controls the immunomodulatory properties of bone marrow mesenchymal stem cells via a microRNA29a/STAT-3 dependent mechanismECCO '16 Amsterdam
Year: 2016
Authors:

A. Oikonomopoulos*1, P. Lacey1, T. Tomakili1, D. Iliopoulos2, 
D. W. Hommes1

1UCLA Centre for Inflammatory Bowel Diseases, Division of Digestive Diseases, Los Angeles, California, United States, 2UCLA Centre for Systems Biomedicine, Division of Digestive Diseases, Los Angeles, California, United States

P033: Anti-TNF-α therapy normalises aberrant cytokine production and homing profile of circulating dendritic cells in Crohn’s diseaseECCO '16 Amsterdam
Year: 2016
Authors:

P. Hendy*1, 2, D. Reddi2, D. Bernardo3, L. Durant2, A. Noble2, N. English2, S. Knight2, A. Hart1

1St Mark’s Hospital, Gastroenterology, LONDON, United Kingdom, 2Imperial College, Antigen Presentation Research Group, London, United Kingdom, 3Hospital Universitario de La Princesa, Department of Immunology, Madrid, Spain

P034: Immunoregulatory properties of human adipose–derived stem cells in inflammatory diseases: differences between Crohn´s disease and obesityECCO '16 Amsterdam
Year: 2016
Authors:

C. Serena*1, 2, N. Keiran2, M. Millan2, M. Ejarque1, 2, R. Fradera3, E. Espin4, K. Roche1, 2, J. Vendrell1, 2, S. Fernandez-Veledo1, 2

1Health Institute Pere Virgili, Research Unit, Tarragona, Spain, 2Hospital Joan XXIII, Tarragona, Spain, 3Hospital St. Pau i Sta Tecla, Tarragona, Spain, 4Hospital Vall d’Hebron, Barcelona, Spain

P035: Lamina propria CD4+LAP+ Foxp3- regulatory cells are involved in limiting the disease extension in Ulcerative ColitisECCO '16 Amsterdam
Year: 2016
Authors:

A. Butera1, A. Amendola1, M. Sanchez2, S. Piroli3, A. Pronio3, D. De Nitto4, R. Pica4, M. Boirivant*1

1Istituto Superiore di Sanità, Dept Infectious, Parasitic and Immune-mediated Diseases, Roma, Italy, 2Istituto Superiore di Sanità, Dept Cell Biology and Neurosciences, Rome, Italy, 3University ‘Sapienza’, Dept General Surgery, ‘P. Stefanini’, Roma, Italy, 4Sandro Pertini Hospital, IBD, GE Unit, Roma, Italy

P036: Colon targeted delivery of tofacitinib inhibits oxazolone-induced colitis in mice, despite low systemic exposureECCO '16 Amsterdam
Year: 2016
Authors:

F. Shen*, P. Brassil, S. Hegde, D. Beattie

Theravance Biopharma, South San Francisco, California, United States