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DOP077: Immunochip analysis identifies multiple susceptibility loci for collagenous colitisECCO '16 Amsterdam
Year: 2016
Authors:

G. Roda*1, H. Jianzhong2, Z. Zhongyang3, J. Torres1, A. Chen4, R. Petras5, D. Pardi6, A. Juga7, G. Levi3, W. Cao8, F. Rieder9, I. Gordon10, K. Hao3, N. Harpaz11, J. Cho12, J.-F. Colombel12, I. Peter3

1Icahn School of Medicine, Gastroenterology, New York, New York, United States, 2Icahn School of Medicine, New York, New York, United States, 3Icahn School of Medicine at Mount Sinai, Medicine, New York, New York, United States, 4Icahn School of Medicine at Mount Sinai, Gastroenterology, New York, New York, United States, 5Ameripath, Pathology, Cleveland, Ohio, United States, 6Mayo Clinic, Gastroenterology, Rochester, Minnesota, United States, 7New York-Presbyterian, Pathology, New York, New York, United States, 8University of Rochester, Pathology, Rochester, Minnesota, United States, 9University of Cleveland, Gastroenterology, Cleveland, Ohio, United States, 10Cleveland Clinic, Department of Anatomic Pathology, Cleveland, Ohio, United States, 11Icahn School of Medicine at Mount Sinai, Department of Gastroenterology, New York, New York, United States, 12Icahn School of Medicine at Mount Sinai, Division of Gastroenterology, New York, New York, United States

DOP078: Risk of malignancy in paediatric inflammatory bowel disease: results from the DEVELOP registryECCO '16 Amsterdam
Year: 2016
Authors:

M. Dubinsky1, J. Hyams2, R. Baldassano3, R. Colletti4, S. Cucchiara5, J. Escher6, W. Faubion7, J. Fell8, B. Gold9, A. Griffiths10, S. Koletzko11, S. Kugathasan12, J. Markowitz13, F. Ruemmele14, G. Veerman*15, H. Winter16, N. Masel17, K. Tang18, M. Thayu18

1Mount Sinai, Icahn School of Medicine, New York, New York, United States, 2Connecticut Children’s Medical Centre, Hartford, Connecticut, United States, 3The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States, 4University of Vermont Children’s Hospital, Burlington, Vermont, United States, 5Sapienza University of Rome/University Hospital, Rome, Italy, 6Erasmus Mc-Sophia Children’s Hospital, Rotterdam, Netherlands, 7Mayo Clinic, Rochester, Minnesota, United States, 8Chelsea and Westminster Hospital, London, United Kingdom, 9Children’s Centre for Digestive Health Care, Atlanta, Georgia, United States, 10Hospital for Sick Children, University of Toronto, Department of Paediatrics, Toronto, Canada, 11Ludwig Maximilians Universität München, Munich, Germany, 12Emory University, Atlanta, Georgia, United States, 13Cohen Children’s Medical Centre Of New York, New York, New York, United States, 14Hôpital Necker-Enfants Malades, Paris, France, 15Universitair Ziekenhaus, Brussels, Belgium, 16Mass General Hospital for Children, Boston, Massachusetts, United States, 17DOCS, Durham, North Carolina, United States, 18Janssen Scientific Affairs, LLC, Horsham, Pennsylvania, United States

DOP079: Predictors of first neoplastic colonic lesion in patients with inflammatory bowel disease undergoing colonoscopic surveillanceECCO '16 Amsterdam
Year: 2016
Authors:

J. Kirchgesner*1, M. Svrcek2, C. Landman1, A. Bourrier1, 
I. Nion-Larmurier1, H. Sokol1, J. Cosnes1, J.-F. Flejou2, L. Beaugerie1

1Saint-Antoine Hospital, AP-HP, Gastroenterology, Paris, France, 2Saint-Antoine Hospital, AP-HP, Pathology, Paris, France

DOP080: Final results of a randomised study comparing high-definition colonoscopy alone with high- definition dye spraying and electronic virtual chromoendoscopy using iSCAN for detection of colonic neoplastic lesions during IBD surveillance colonoscopyECCO '16 Amsterdam
Year: 2016
Authors:

M. Iacucci*1, M. Fort Gasia1, A. Oluseyi1, R. Panaccione1, S. Gui X2, S. Urbanski3, P. Minoo3, S. Ghosh1

1University of Calgary, Gastroenterology, Calgary, Canada, 2University of Calgary, Pathology, Calgary, Canada, 3University of Calgary, Calgary, Canada

DOP081: Outcomes of colitis-associated dysplasia after referral from the community to a tertiary centreECCO '16 Amsterdam
Year: 2016
Authors:

D. Rubin*, N. Krugliak Cleveland, D. Rodriquez

University of Chicago Medicine, Inflammatory Bowel Disease Centre, Chicago, Illinois, United States

DOP082: Proximity extension assay immunoassay technology identifies novel serum biomarkers that can diagnose and classify inflammatory bowel diseases: IBD Character ConsortiumECCO '16 Amsterdam
Year: 2016
Authors:

R. Kalla*1, A. Ocklind2, C. Petrén2, N. Nordberg2, N. Kennedy1, N. Ventham1, E. Pettersson2, D. Bergemalm3, J. Lindström4, S. Vatn4, H. Hjortswang5, E. Nimmo1, H. Drummond1, P. Ricanek6, F. Dahl4, D. Wilson1, J. Jahnsen4, F. Gomollón7, M. Pierik8, J. Söderholm9, M. Vatn4, J. Halfvarson3, IBD Character Consortium1, J. Satsangi1

1University of Edinburgh, Gastroenterology, Edinburgh, United Kingdom, 2Olink, Bioscience, Uppsala, Sweden, 3Örebro University, Department of Gastroenterology, Faculty of Medicine and Health, Örebro, Sweden, 4Oslo University Hospital, Department of Gastroenterology, Oslo, Norway, 5Linköping University Hospital, Department of Gastroenterology, Linköping, Sweden, 6Akershus University Hospital, Deaprtment of Gastroenterology, Lorenskog, Norway, 7University of Zaragosa, Gastroenterology, Zaragosa, Spain, 8Maastricht University Medical Centre (MUMC), Department of Gastroenterology and Hepatology, Maastricht, Netherlands, 9Linköping University Hospital, Department of Surgery, Linköping, Sweden

DOP083: Faecal calprotectin improves the predictive power of 3 practical indices for mucosal healing amongst patients with Crohn’s disease: results from PREDICTECCO '16 Amsterdam
Year: 2016
Authors:

W. Sandborn*1, R. Panaccione2, J.-F. Colombel3, E. Louis4, A. Robinson5, K. Wallace5, M. Bereswill6, M. Shapiro5, N. Chen5, M. Skup5, S. Wang5, R. Thakkar5, J. Chao5

1University of California, San Diego, La Jolla, California, United States, 2University of Calgary, Medicine, Calgary, Canada, 3Centre Hospitalier Universitaire de Lille, Lille, France, 4University of Liège, Liège, Belgium, 5AbbVie Inc., North Chicago, Illinois, United States, 6AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany

DOP084: Identification of a potential new prognostic biomarker to select inflammatory bowel disease patients that fail standard therapyECCO '16 Amsterdam
Year: 2016
Authors:

M. S. Pereira1, S. Campos1, A. M. Dias1, I. Pedroto2, C. A. Reis1, 3, L. Maia2, R. Marcos-Pinto2, 3, P. Lago2, S. S. Pinho*1, 3

1Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) & Institute for Research and Innovation in Health (i3S), Porto, Portugal, 2Centro Hospitalar do Porto, Department of Gastroenterology, Porto, Portugal, 3Institute of Biomedical Sciences of Abel Salazar (ICBAS), University of Porto, Porto, Portugal

DOP085: Ileocolonic involvement and diagnosis is related to fragments of the extracellular matrix measured in serum of patients with Crohn’s diseaseECCO '16 Amsterdam
Year: 2016
Authors:

J. H. Mortensen*1, M. D. Jensen2, J. Kjeldsen2, A. Krag2, M. Karsdal1, A.-C. Bay-Jensen1

1Nordic Bioscience, Biomarkers & Research, Herlev, Denmark, 2Odense University Hospital, Department of Gastroenterology, Odense, Denmark

DOP086: Faecal chitinase 3-like 1 is a reliable marker as accurate as faecal calprotectin in detecting endoscopic activity in adult patients with inflammatory bowel diseasesECCO '16 Amsterdam
Year: 2016
Authors:

A. Buisson*1, 2, E. Vazeille1, 2, R. Minet Quinard3, M. Goutte1, 2, D. Bouvier3, F. Goutorbe1, B. Pereira4, N. Barnich2, G. Bommelaer1, 2

1University Hospital Estaing, Gastroenterology Department, Clermont-Ferrand, France, 2UMR 1071 Inserm/Université d’Auvergne; USC-INRA 2018, Microbes, Intestine, Inflammation and Susceptibility of the host, Clermont-Ferrand, France, 3University Hospital G. Montpied, Biochemistry laboratory, Clermont-Ferrand, France, 4GM – Clermont-Ferrand University and Medical Centre, Biostatistics Unit, Clermont-Ferrand, France

DOP087: MMP degraded type III collagen is a novel serological biomarker for penetrating (Montreal B3) Crohn’s diseaseECCO '16 Amsterdam
Year: 2016
Authors:

W. T. van Haaften*1, 2, J. H. Mortensen3, M. A. Karsdal3, A.-C. Bay-Jensen3, G. Dijkstra2, P. Olinga1

1University of Groningen, Department of Pharmaceutical Technology and Biopharmacy, Groningen, Netherlands, 2University Medical Centre Groningen, Department of Gastro-enterology and Hepatology, Groningen, Netherlands, 3Nordic Bioscience, Biomarkers and Research, Herlev, Denmark

DOP088: Inflammatory biomarkers in serum discriminate Crohn’s disease and ulcerative colitis from healthy controlsECCO '16 Amsterdam
Year: 2016
Authors:

E. Andersson*1, D. Bergemalm1, R. Kruse1, M. D’Amato2, D. Repsilber1, J. Halfvarson1

1Örebro University, Faculty of Medicine and Health, Örebro, Sweden, 2Karolinska Institutet, Department of Medicine, Solna, Sweden

DOP089: Microbiota profiles in treatment-naïve Norwegian IBD and non-IBD patients: part of the European Union IBD character consortiumECCO '16 Amsterdam
Year: 2016
Authors:

P. Ricanek*1, S. Vatn1, T. Lindahl2, E. Ciemniejewska2, J. Jahnsen1, C. Casen2, M. H. Vatn1

1Akershus University Hospital, Department of Gastroenterology, Lørenskog/Nordbyhagen, Norway, 2Genetic Analysis AS, Oslo, Norway

DOP090: The role of the microbiome in clinical response to golimumab in ulcerative colitisECCO '16 Amsterdam
Year: 2016
Authors:

C. Monast*, S. Telesco, K. Li, K. Hayden, C. Brodmerkel

Janssen R & D, LLC, Spring House, Pennsylvania, United States

OP001: A phase III randomised controlled trial of Cx601, expanded allogeneic adipose-derived mesenchymal stem cells (eASC), for complex perianal fistulas in Crohns diseaseECCO '16 Amsterdam
Year: 2016
Authors:

J. Panés*1, D. García-Olmo2, G. Van Assche3, J. F. Colombel4, W. Reinisch5, D. C. Baumgart6, M. Nachury7, M. Ferrante3, L. Kazemi-Shirazi5, J. C. Grimaud8, F. de la Portilla9, E. Goldin10, A. Leselbaum11, M. C. Diez11, S. Danese12

1Hospital Clinic Barcelona, Barcelona, Spain, 2Hospital U. Fundación Jiménez-Díaz, Madrid, Spain, 3University Hospitals Leuven, KU Leuven, Leuven, Belgium, 4Icahn School of Medicine at Mount Sinai, New York, New York, United States, 5Medical University of Vienna, Vienna, Austria, 6Charité Medical School - Humboldt-University of Berlin, Berlin, Germany, 7CHU Lille, Lille, France, 8Hôpital Nord, Marseille, France, 9Hospital Virgen del Rocío, Sevilla, Spain, 10Sharee Zedek MC, Jerusalem, Israel, 11TiGenix, Madrid, Spain, 12Istituto Clinico Humanitas, Milano, Italy

OP002: Histopathological response and remission after dual topical application of the Toll-like receptor 9 agonist DIMS0150 in patients with moderate-to-severe ulcerative colitisECCO '16 Amsterdam
Year: 2016
Authors:

R. Atreya*1, A. Öst2, C. Admyre3, A. Karlsson3, T. Knittel3, J. Kowalski3, F. Scaldaferi4, M. Neurath1, C. Hawkey5

1University of Erlangen-Nuernberg, Department of Medicine 1, Erlangen, Germany, 2Aleris Medilab, Department of Pathology and Cytology, Täby, Sweden, 3Index Pharmaceuticals, Stockholm, Sweden, 4Catholic University of Rome, Internal Medicine Department / Gastroenterology Division, Rome, Italy, 5Nottingham University Hospitals, Department of Gastroenterology, Nottingham, United Kingdom

OP003: Predicting short and medium-term efficacy of the biosimilar infliximab: trough levels/do anti-drug antibodys or clinical/biochemical markers play a more important role?ECCO '16 Amsterdam
Year: 2016
Authors:

P. A. Golovics*1, Z. Vegh1, M. Rutka2, K. Gecse1, A. Balint2, K. Farkas2, J. Banai3, L. Bene4, B. Gasztonyi5, T. Kristof6, L. Lakatos7, P. Miheller8, K. Palatka9, A. Patai10, A. Salamon11, T. Szamosi3, Z. Szepes12, G.T. Toth13, A. Vincze14, E. Biro15, B. Lovasz1, Z. Kurti1, F. Nagy12, T. Molnar2, P. Lakatos1

1Semmelweis University, First Department of Medicine, Budapest, Hungary, 2University of Szeged, First Department of Medicine, Szeged, Hungary, 3Military Hospital, State Health Centre, Department of Gastroenterology, Budapest, Hungary, 4Peterfy Hospital, First Department of Medicine, Budapest, Hungary, 5Zala County Hospital, Second Department of Medicine, Zalaegerszeg, Hungary, 6B-A-Z County and University Teaching Hospital, Second Department of Medicine, Miskolc, Hungary, 7Csolnoky F. Province Hospital, Department of Medicine, Veszprem, Hungary, 8Semmelweis University, Second Department of Medicine, Budapest, Hungary, 9University of Debrecen, Institute of Medicine, Department of Gastroenterology, Debrecen, Hungary, 10Markusovszky Hospital, First Department of Medicine and Gastroenterology, Szombathely, Iceland, 11Tolna County Teaching Hospital, First Department of Gastroenterology, Szekszard, Hungary, 12University of Szeged, First Department of Internal Medicine, Szeged, Hungary, 13Janos Hospital, Department of Gastroenterology, Budapest, Hungary, 14University of Pécs, First Department of Medicine, Pécs, Hungary, 15Semmelweis University, Department of Laboratory Medicine, Budapest, Hungary

OP004: Gene expression profiling indicates similar molecular pathways are active in adult and paediatric Crohns diseaseECCO '16 Amsterdam
Year: 2016
Authors:

A. Stojmirovic*, R. Dobrin, R. Strauss, D. Chan, K. Li, J. Friedman

Janssen R & D, LLC, Spring House, Pennsylvania, United States

OP005: A variable number of tandem repeat polymorphism in the promotor region of the neonatal Fc receptor affects anti-tumour necrosis factor serum levels in inflammatory bowel diseaseECCO '16 Amsterdam
Year: 2016
Authors:

T. Billiet*1, I. Cleynen1, M. Ferrante2, G. Van Assche2, A. Gils3, S. Vermeire2

1Department of Clinical and Experimental Medicine, KU Leuven, Translational Research in Gastrointestinal Disorders (TARGID), Leuven, Belgium, 2University Hospitals Leuven, Gastroenterology - 
Translational Research Centre for Gastrointestinal Disorders (TARGID), Leuven, Belgium, 3KU Leuven, Laboratory for Therapeutic and Diagnostic Antibodies, Leuven, Belgium

OP006: Autophagy regulates dendritic cell migration through Rac1: implications for thiopurine therapyECCO '16 Amsterdam
Year: 2016
Authors:

M. Wildenberg*1, P. Koelink2, K. Diederen2, A. te Velde2, V. Nuij3, M. Peppelenbosch3, M. Nobis4, O. Sansom4, C.J. van der Woude3, G. D’Haens1, G. van den Brink1

1Academic Medical Centre, Gastroenterology and Hepatology, Amsterdam, Netherlands, 2Academic Medical Centre, Tytgat Institute, Amsterdam, Netherlands, 3Erasmus Medical Centre, Department of Gastroenterology and Hepatology, Rotterdam, Netherlands, 4Beatson Institute for Cancer Research, Glasgow, United Kingdom