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P548: Limited clinical value in assessing the distribution of endoscopic disease activity in patients with ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

M. Ferrante*, B. Verstockt, L. Gijbels, G. Van Assche, S. Vermeire

University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium

P549: Systemic cytomegalovirus infection is a relevant factor affecting short- and long-term outcomes of patients with acute severe ulcerative colitis: An 11-year experienceECCO '18 Vienna
Year: 2018
Authors:

F.S. Macaluso1*, S. Compagnoni1, S. Renna1, S. Maisano1, A. Casà1, G. Solina2, A.G. Rizzo3, F. La Seta4, M. Ventimiglia1, A. Orlando1, M. Cottone1

1Division of Internal Medicine, “Villa Sofia-Cervello” Hospital, Palermo, Italy, 2Unit of Surgery, “Villa Sofia-Cervello” Hospital, Palermo, Italy, 3Unit of Pathology, Villa Sofia-Cervello'' Hospital, Palermo, Italy, 4Radiology Unit, “Villa Sofia-Cervello” Hospital, Palermo, Italy

P550: Early 12-week ultrasound response to treatment, used as a predictor of response at 6 months in Crohn’s disease: A prospective cohort studyECCO '18 Vienna
Year: 2018
Authors:

J. Halasz1*, C. Lu1, G. Kaplan1,2, D. Tanyingoh2, C. Seow1, R. Panaccione1, S. Devlin1, S. Wilson3, K. Novak1

1University of Calgary, Gastroenterology, Calgary, Canada, 2University of Calgary, Community Health Sciences, Calgary, Canada, 3University of Calgary, Foothills Medical Centre, Diagnostic Imaging, Calgary, Canada

P551: 6-Thioguanine nucleotide levels are associated with mucosal healing in patients with Crohn’s disease: A multi-centre, international studyECCO '18 Vienna
Year: 2018
Authors:

R. Mao1, J. Guo1, R. Luber2, B.-l. Chen1, Y. He1, Z.-r. Zeng1, S. Ben-Horin3, M. Sparrow2, R. Xavier4, M.-h. Chen1*

1First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 2The Alfred Hospital, Melbourne, Australia, 3Sheba Medical Center, Tel-aviv, Israel, 4University Hospital of Saint Etienne, Saint Etienne, France

P552: Early use of vedolizumab vs. infliximab in biologic-naive patients with ulcerative colitis: A real-world analysis of healthcare utilisationECCO '18 Vienna
Year: 2018
Authors:

H. Patel1*, J.M. Khalid1, S. Shah2, R. Shah3, A. Berger2

1Takeda Development Centre Europe Ltd., Evidence and Value Generation, London, UK, 2Evidera, Real World Evidence, Waltham, MA, USA, 3Evidera, Real World Evidence, London, UK

P553: Development of an enzyme-linked immunosorbent assay for therapeutic drug monitoring of golimumabECCO '18 Vienna
Year: 2018
Authors:

C. Berger1*, A. Pilch1, J. Ruppert1, F.-P. Armbruster1, J. Stein2,3, K. Farrag2,3

1Immundiagnostik AG, Bensheim, Germany, 2Interdisciplinary Crohn Colitis Centre Rhein-Main, Frankfurt/Main, Germany, 3DGD Clinics Sachsenhausen, Frankfurt/Main, Germany

P554: Incidence and impact of immunogenicity in a randomised, double-blind phase III study comparing a proposed infliximab biosimilar (PF-06438179/GP1111) with reference infliximabECCO '18 Vienna
Year: 2018
Authors:

R. Palaparthy1*, S. Schmitt2, M.I. Rehman3, C.-H. Cai1, K. Wang1, O. von Richter2

1Pfizer Inc., Biosimilars Development, New York, USA, 2Global Clinical Development, Biopharmaceuticals, Hexal AG (a Sandoz company), Holzkirchen, Germany, 3Pfizer Inc., Andover, USA

P555: Coagulation disorders in a population of patients with inflammatory bowel diseaseECCO '18 Vienna
Year: 2018
Authors:

J. Pinho1*, F. Pires1, D. Martins1, P. Sousa1, E. Cancela1, M. Farinha2, A. Silva1, P. Ministro1

1Centro Hospitalar Tondela-Viseu, Gastroenterology, Viseu, Portugal, 2Centro Hospitalar Tondela-Viseu, Pathology, Viseu, Portugal

P556: Cyclosporine in acute severe steroid-refractory ulcerative colitis: Short-and long-term outcomesECCO '18 Vienna
Year: 2018
Authors:

A. Hammami*, B. Hasnaoui, S. Hachicha, M. Ksiaa, H. Jaziri, N. Elleuch, A. Brahem, S. Ajmi, A. Ben Slama, A. Jmaa

Hospital University of Sahloul, Gastroenterology, Sousse, Tunisia

P557: Cost-effectiveness of infliximab vs. surgery for severe chronic ulcerative colitis: a Markov analysisECCO '18 Vienna
Year: 2018
Authors:

S. Holubar1*, P. Dulai2, B. Piazik3, S. Finlayson4, B. Udeh5

1Cleveland Clinic, Department of Colon and Rectal Surgery, Cleveland, USA, 2University of California San Diego, Medicine, San Diego, USA, 3Elliot Health Systems, Manchester, USA, 4University of Utah, Surgery, Salt Lake City, USA, 5Cleveland Clinic, Clinical Transformation, Cleveland, USA

P558: Golimumab improves patient-reported work productivity and activity impairment in patients with ulcerative colitis: Interim results from a non-interventional trial in GermanyECCO '18 Vienna
Year: 2018
Authors:

N. Teich1, H. Grümmer2, E. Jörgensen3, T. Liceni4, F. Holtkamp-Endemann5, F. Cornillie6, S. Hohenberger7, T. Fischer7*

1Internistische Gemeinschaftspraxis für Verdauungs- und Stoffwechselkrankheiten Leipzig und Schkeuditz, Leipzig, Germany, 2Praxis Grümmer, Potsdam, Germany, 3Magen Darm Zentrum Remscheid, Remscheid, Germany, 4MVZ für Gastroenterologie am Bayerischen Platz, Berlin, Germany, 5Gastroenterologische Gemeinschaftspraxis am Germania-Campus, Münster, Germany, 6MSD, Global Medical Affairs, Luzern, Switzerland, 7MSD, Medical Affairs, Haar, Germany

P559: Tacrolimus as a topical therapy for perianal Crohn’s diseaseECCO '18 Vienna
Year: 2018
Authors:

B. Nanaeva1*, M. Shapina2, I. Khalif1

1Federal State Establishment State Scientific Centre of Coloproctology, Department of Inflammatory and Functional Bowel Diseases Study, Moscow, Russian Federation, 2Federal State Budgetary Institute State Scientific Center of Coloproctology of Russian Ministry of Health, Gastroenterology, Moscow, Russian Federation

P560: Granulocyte–monocyte apheresis combination therapy after loss of response to anti-TNF drugsECCO '18 Vienna
Year: 2018
Authors:

I. Rodríguez-Lago1*, L. Sempere2, A. Gutiérrez2,3, B. Beltrán4, E. Saez4, E. Hinojosa5, M. Mora5, F. Cañete6, M. Mañosa6, S. Khorrami7, D. Ginard7, J.L. Cabriada1

1Hospital de Galdakao, Gastroenterology, Galdakao, Spain, 2Hospital General Universitario de Alicante, Gastroenterology, Alicante, Spain, 3CIBEREHD (Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas), Alicante, Spain, 4Hospital De La Fe, Gastroenterology, Valencia, Spain, 5Hospital de Manises, Gastroenterology, Manises, Spain, 6Hospital Universitari Germans Trias I Pujol, Gastroenterology, Badalona, Spain, 7Hospital Son Espases, Gastroenterology, Palma de Mallorca, Spain

P561: A comparison of medication adherence and persistence between intravenous biologics and oral small-molecule therapiesECCO '18 Vienna
Year: 2018
Authors:

S. Kane1, K. Moran2, K. Null2, Z. Huang2, T. Lissoos2*

1Mayo Clinic, Rochester, USA, 2Takeda Pharmaceuticals USA, Inc., Deerfield, USA

P562: Role, efficacy and safety of budesonide multi-matrix in ulcerative colitis in real life: A study in three Italian third-level centresECCO '18 Vienna
Year: 2018
Authors:

S. Landi1*, N. Mezzina2, S. Carmagnola2, M. Bosani3, E. Filippi4, L. Pastorelli4, S. Grillo1, A. Massari2, A. Cassinotti2, P. Moulteni2, A. Dell'Era2, S. Ardizzone2, G. Maconi2

1Gastroenterology Unit, University of Parma, Parma, Italy, 2Gastrointestinal Unit, ASST Fatebenefratelli Sacco, DIBIC “L. Sacco” University of Milan, Milan, Italy, 3Gastroenterology and Endoscopic Unit, Legnano Hospital, Legnano, Italy, 4I.R.C.C.S. Policlinico San Donato Gastroenterology and Digestive Endoscopy Unit, San Donato Milanese (Milan), Italy

P563: Stopping anti-TNFα monotherapy in Crohn's disease patients in deep remission and favourable disease characteristics is associated with a high rate of relapseECCO '18 Vienna
Year: 2018
Authors:

K. Soufleris1*, N. Kafalis1, K. Fasoulas1, G. Lazaraki1, I. Pilpilidis1, D. Tzilves1, O. Giouleme2

1Theagenion Cancer Hospital of Thessaloniki, Gastroenterology Department, Thessaloniki, Greece, 2Hippokration General Hospital of Thessaloniki, Second Propedeutic Department of Internal Medicine, Thessaloniki, Greece

P564: Indigo naturalis induces mucosal healing in patients with ulcerative colitis: A multicentre randomised controlled trialECCO '18 Vienna
Year: 2018
Authors:

M. Naganuma1*, S. Sugimoto1, K. Mitsuyama2, T. Kobayashi3, N. Yoshimura4, H. Ohi5, K. Matsuoka6, T. Hisamatsu7, K. Watanabe8, T. Abe9, M. Watanabe6, T. Hibi3, Y. Suzuki10, T. Kanai1, INDIGO study group

1Keio University, Division of Gastroenterology and Hematology, Tokyo, Japan, 2Kurume University School of Medicine, Division of Gastroenterology, Department of Medicine, Kurume, Japan, 3Kitasato University Kitasato Institute Hospital, Center for Advanced IBD Research and Treatment, Tokyo, Japan, 4Tokyo Yamate Medical Center, Department of Internal Medicine, Division of IBD, Tokyo, Japan, 5Imamura Hospital, Department of Gastroenterology, Kagoshima, Japan, 6Tokyo Medical and Dental University, Department of Gastroenterology and Hepatology, Tokyo, Japan, 7Kyorin University School of Medicine, The Third Department of Internal Medicine, Mitaka, Japan, 8Hyogo College of Medicine, Department of Intestinal Inflammation Research, Nishinomiya, Japan, 9Keio University School of Medicine, Medicine and Public Health, Biostatistics Unit at Clinical and Translational Research Center, Tokyo, Japan, 10Toho University Sakura Medical Center, Department of Internal Medicine, Division of IBD, Sakura, Japan

P565: Real-world use of azathioprine metabolites changes clinical management of inflammatory bowel diseaseECCO '18 Vienna
Year: 2018
Authors:

S. Tuson1, L. Wilson1, L. Yang2,3, D. Loomes1,3*

1Vancouver Island IBD Clinic, Victoria, Canada, 2Island Health, Department of Laboratory Medicine, Pathology and Medical Genetics, Victoria, Canada, 3University of British Columbia, Faculty of Medicine, Vancouver, Canada

P566: Effect of polyethylene glycol (PEG) bowel preparation on faecal calprotectin levels in patients with ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

C. Herrera-deGuise*, E. Varela, V. Robles, F. Casellas, N. Borruel

Hospital Universitari Vall d'Hebron, Digestive Disease Research Unit, Barcelona, Spain

P567: Long-term outcome of perianal fistulae treated with anti-TNFα therapy in a cohort of Saudi patients with Crohn’s disease based on Parks classificationECCO '18 Vienna
Year: 2018
Authors:

N. Azzam1*, O. Alharbi1, A. Aljebreen1, A. Mohammed1, S. Bahammam1, A. Bashmail1, Y. Alomar1, M. Mosli2, M. Almadi1

1King Saud University, Medicine, Riyadh, Saudi Arabia, 2King Abdul-Aziz University, Medicine, Jeddah, Saudi Arabia