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P528: Patients’ perspectives on switching from reference infliximab to CT-P13 biosimilar in patients with inflammatory bowel disease: A 12-month prospective observational cohort studyECCO '18 Vienna
Year: 2018
Authors:

N. Petitdidier1*, C. Gagniere1, A.L. Rentien1, J. Tannoury1, Y. Le Baleur2, F. Mesli1, I. Sobhani1, A. Amiot1

1Hopital Henri Mondor, Gastroenterology, Créteil, France, 2Hopital Saint Joseph, Gastroenterology, Paris, France

P529: Longer duration of vancomycin prevents recurrence of C. difficile in patients with inflammatory bowel diseaseECCO '18 Vienna
Year: 2018
Authors:

D. Lei*, M.J. Andersen Jr., R. Weisshof, N. Meter, D.T. Rubin

University of Chicago Medicine, Inflammatory Bowel Disease Center, Chicago, USA

P530: Psychosexual dysfunction in Greek patients with inflammatory bowel disease in remissionECCO '18 Vienna
Year: 2018
Authors:

N. Dimitriadis, D. Xanthis, P. Paschos, A. Katsoula, N. Grammatikos, A. Tsimperidis, K. Soufleris, O. Giouleme*

Aristotle University, Hippokration Hospital, Second Propedeutic Department of Internal Medicine, Thessaloniki, Greece

P531: Tuberculin skin test conversion rate in inflammatory bowel disease patients receiving anti-TNFα agentsECCO '18 Vienna
Year: 2018
Authors:

M. Fragaki*, G. Paspatis, K. Karmiris

Venizelion General Hospital, Department of Gastroenterology, Heraklion, Greece

P532: Efficacy of combination therapy with cyclosporin and vedolizumab in inflammatory bowel diseases refractory to anti-TNF agentsECCO '18 Vienna
Year: 2018
Authors:

M. Rutka*, K. Szántó, R. Bor, A. Bálint, A. Fábián, A. Milassin, Z. Szepes, K. Farkas, T. Molnar

University of Szeged, 1st Department of Medicine, Szeged, Hungary

P533: Correlation of endoscopic and clinical endpoints during induction therapy in patients with moderate-to-severe Crohn’s disease: Analysis from CELEST studyECCO '18 Vienna
Year: 2018
Authors:

W.J. Sandborn1*, B. Feagan2, J.D. Lewis3, S. Danese4, W. Reinisch5, D.T. Rubin6, W. Zhou7, F. Cataldi7, Q. Zhou7, S. Goteti7, A.P. Lacerda7

1University of California San Diego, La Jolla, USA, 2Robarts Clinical Trials, London, Canada, 3Perelman School of Medicine at The University of Pennsylvania, Philadelphia, USA, 4Istituto Clinico Humanitas, Milan, Italy, 5Medical University of Vienna, Vienna, Austria, 6University of Chicago Medicine, Chicago, USA, 7AbbVie Inc., North Chicago, USA

P534: Spontaneous intra-abdominal abscess in Crohn's disease: Efficacy of non-surgical management and prognostic factorsECCO '18 Vienna
Year: 2018
Authors:

A. Labidi1*, S. Hamdi1, M. Ben Abbes1, N. Ben Mustapha1, M. Hafi1, H. Maghrebi2, M. Fekih1, L. Zouiten1, M. Serghini1, J. Boubaker1

1Rabta Hospital, Gastroenterology “A”, Tunis, Tunisia, 2Rabta Hospital, Surgery “A”, Tunis, Tunisia

P535: The use of therapeutic drug monitoring for infliximab and adalimumab in inflammatory bowel disease: Practice patterns, understanding and interpretationECCO '18 Vienna
Year: 2018
Authors:

M.A. Samaan*, P.M. Irving

Guy's and St Thomas' Hospital, Gastroenterology, London, UK

P536: Minimally invasive gasless technique for ileocolic resection using an existing McBurney incisionECCO '18 Vienna
Year: 2018
Authors:

L. Fazzolari1, G. Bagaglini1, S. D'Ugo1,2*, B. Sensi1, A. Di Giorgio1, G. Sica1

1Tor Vergata University, Department of Surgery, Rome, Italy, 2Tor Vergata University, Surgery, Rome, Italy

P537: Adalimumab: Relevance of drug trough levels and antibodies assessment in the prognosis of Crohn’s diseaseECCO '18 Vienna
Year: 2018
Authors:

D. Perdigoto, C. Macedo*, F. Portela, S. Lopes, M. Ferreira, S. Mendes, M. Ferreira, L. Tomé

Coimbra Hospital and University Center, Gastroenterology, Coimbra, Portugal

P538: Enteral nutrition for the maintenance of remission in adults with inactive Crohn’s disease: A meta-analysisECCO '18 Vienna
Year: 2018
Authors:

W. Tang*

The Second Affiliated Hospital of Soochow University, Gastroenterology, Suzhou, China

P539: Transcriptional changes in mucosal inflammation associated with an autoimmune protocol diet for ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

G. Konijeti1,2, B. Molparia2,3, E. Akhtar*, X. Wang2, J. Chang4, J. Lewis5, A. Chandrasekaran6, S. Groven7, G. Oliveira2, A. Torkamani2,3

1Scripps Clinic, Division of Gastroenterology, La Jolla, USA, 2The Scripps Research Institute, Scripps Translational Science Institute, La Jolla, USA, 3The Scripps Research Institute, Department of Integrative Structural and Computational Biology, La Jolla, USA, 4University of California, San Diego, Division of Gastroenterology, La Jolla, USA, 5University of Pennsylvania, Center for Clinical Epidemiology and Biostatistics, Philadelphia, USA, 6Scripps Clinic, Department of Internal Medicine, La Jolla, USA, 7San Diego State University, School of Exercise and Nutritional Sciences, San Diego, USA

P540: Early response as a prognostic factor for vedolizumab: A real-life experience from a single Italian tertiary centreECCO '18 Vienna
Year: 2018
Authors:

N. Mezzina1*, A. Cassinotti1, S. Carmagnola1, A. Massari1, S. Grillo2, S. Landi2, G. Maconi1, S. Ardizzone1

1ASST Fatebenefratelli Sacco, DIBIC “L. Sacco” University of Milan, Gastrointestinal Unit, Milan, Italy, 2University Hospital of Parma, Department of Gastroenterology and Digestive Endoscopy, Parma, Italy

P541: Clinical factors associated with discontinuation of combo or monotherapy for Crohn’s disease: A sub-analysis of a prospective randomised clinical trial (DIAMOND study)ECCO '18 Vienna
Year: 2018
Authors:

T. Hisamatsu1*, T. Matsumoto2, K. Watanabe3, H. Nakase4, S. Motoya5, N. Yoshimura6, T. Ishida7, S. Kato8, T. Nakagawa9, M. Esaki10, M. Nagahori11, T. Matsui12, Y. Naito13, T. Kanai14, Y. Suzuki15, M. Nojima16, M. Watanabe17, T. Hibi18, DIAMOND study group1

1Kyorin University School of Medicine, Third Department of Internal Medicine, Tokyo, Japan, 2Iwate Medical University School of Medicine, Division of Gastroenterology, Department of Medicine, Morioka, Japan, 3Hyogo College of Medicine, Department of Intestinal Inflammation Research, Nishinomiya, Japan, 4Sapporo Medical University School of Medicine, Department of Gastroenterology and Hepatology, Sapporo, Japan, 5Sapporo Kosei General Hospital, Inflammatory Bowel Disease Center, Sapporo, Japan, 6Tokyo Yamate Medical Center, Department of Medicine, Division of Gastroenterology, Tokyo, Japan, 7Ishida Clinic of IBD and Gastroenterology, Oita, Japan, 8Saitama Medical Center, Saitama Medical University, Department of Gastroenterology and Hepatology, Saitama, Japan, 9Graduate School of Medicine, Chiba University, Department of Gastroenterology and Nephrology, Chiba, Japan, 10Graduate School of Medical Sciences, Kyushu University, Department of Medicine and Clinical Science, Fukuoka, Japan, 11Tokyo Medical and Dental University, Department of Gastroenterology and Hepatology, Tokyo, Japan, 12Fukuoka University Chikushi Hospital, Department of Gastroenterology, Chikushino, Japan, 13Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Department of Molecular Gastroenterology and Hepatology, Kyoto, Japan, 14Keio University School of Medicine, Department of Internal Medicine, Tokyo, Japan, 15Toho University Sakura Medical Center, Department of Internal Medicine, Sakura, Japan, 16The Institute of Medical Science Hospital, The University of Tokyo, Center for Translational Research, Tokyo, Japan, 17Tokyo Medical and Dental University, Department of Gastroenterology and Hepatology, Tokyo, Japan, 18Kitasato University Kitasato Institute Hospital, Center for Advanced IBD Research and Treatment, Tokyo, Japan

P542: Infliximab salvage therapy in acute severe ulcerative colitis: A systematic review and meta-analysisECCO '18 Vienna
Year: 2018
Authors:

M.C. Choy1,2,3*, D. Seah1, D.M. Faleck4, S.C. Shah4, A. Al-Khoury5, Y.-K. An6, G. Radford-Smith6, T. Bessissow5, A.C. Ford7,8, M. Dubinksy4, N. Yeomans2, P. De Cruz1,2

1Austin Health, Department of Gastroenterology, Melbourne, Australia, 2University of Melbourne, Austin Academic Centre, Melbourne, Australia, 3St Vincent's Hospital, Department of Gastroenterology, Melbourne, Australia, 4Mount Sinai, Icahn School of Medicine, New York, USA, 5McGill University Health Centre, Division of Gastroenterology, Montreal, Canada, 6Royal Brisbane and Women's Hospital, Department of Gastroenterology and Hepatology, Brisbane, Australia, 7Leeds Teaching Hospitals NHS Trust, Gastroenterology Institute, Leeds, UK, 8University of Leeds, Leeds Institute of Biomedical and Clinical Sciences, Leeds, UK

P543: Higher post-induction infliximab serum trough levels are associated with healing of fistulising perianal Crohn’s disease in childrenECCO '18 Vienna
Year: 2018
Authors:

W. El-Matary1*, T. Walters2, H. Huynh3, J. deBruyn4, D. Mack5, K. Jacobson6, M. Sherlock7, P. Church2, E. Wine3, M. Carroll3, E. Benchimol5, S. Lawrence6, A. Griffiths2

1University of Manitoba, Pediatrics, Winnipeg, Canada, 2Hospital for Sick Children, University of Toronto, Department of Paediatrics; Department of Gastroenterology, Hepatology and Nutrition, Toronto, Canada, 3University of Alberta, Department of Pediatrics, Edmonton, Canada, 4Pediatrics, University of Calgary, Calgary, Canada, 5University of Ottawa, Department of Pediatrics, Ottawa, Canada, 6BC Children's Hospital, Vancouver, Canada, 7McMaster University, Department of Pediatrics, Hamilton, Canada

P544: Histological remission following ozanimod treatment is associated with concurrent clinical remission and endoscopic mucosal healing: Results from the TOUCHSTONE studyECCO '18 Vienna
Year: 2018
Authors:

B.G. Feagan1*, W.J. Sandborn2, G. D'Haens3, R.K. Pai4, S.B. Hanauer5, D.C. Wolf6, S. Vermeire7, S. Ghosh8, B.G. Levesque9, K. Shan9, R. Aranda9, W.J. Liu9, A. Olson9

1Robarts Clinical Trials, Western University, Ontario, Canada, 2University of California - San Diego, San Diego, USA, 3Academic Medical Center, Amsterdam, The Netherlands, 4Mayo Clinic, Department of Laboratory Medicine and Pathology, Scottsdale, USA, 5Northwestern University Feinberg School of Medicine, Chicago, USA, 6Atlanta Gastroenterology Associates, Atlanta, USA, 7University of Leuven, Leuven, Belgium, 8University of Calgary, Calgary, Canada, 9Receptos, a Wholly Owned Subsidiary of Celgene, San Diego, USA

P545: Antigenic response to CT-P13 and remicade in inflammatory bowel disease patients shows similar epitope recognitionECCO '18 Vienna
Year: 2018
Authors:

J. Goncalves1*, M. Santos1, R. Acurcio1, I. Iria1, L. Gouveia1, P. Brito1, A.C. Cunha Santos1, A. Barbas2,3, J. Galvão2, I. Barbosa2, F. Aires da Silva4, A. Alcobia5, M. Cavaco6, M. Cardoso1, J. Delgado Alves7,8, J. Carey9, T. Dorner10, J. Eurico Fonseca6,11, C. Palmela12, J. Torres12, C. Lima Vieira13, D. Trabuco13, G. Fiorino14, A. Strik15, M. Yavzori16, I. Rosa17, L. Correia18, F. Magro19, G. D'Haens15, S. Ben-Horin16, P. Lakatos20,21, S. Danese14

1Faculdade Farmacia Universidade Lisboa, iMed - Research Institute for Medicines, Lisboa, Portugal, 2iBET, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal, 3Bayer Portugal, Carnaxide, Portugal, 4Centro Interdisciplinar de Investigação em Sanidade Animal (CIISA), Faculdade de Medicina Veterinária, University of Lisbon, Lisboa, Portugal, 5Hospital Garcia de Orta (HGO), Almada, Portugal, 6Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal, 7CEDOC/NOVA Medical School, Lisbon, Portugal, 8Immunomediated Systemic Diseases Unit (UDIMS), Fernando Fonseca Hospital, Amadora, Portugal, 9Galway University Hospitals, Department of Rheumatology, Galway, Ireland, 10Charite Universitaetsmedizin Berlin, Department Medicine Rheumatology and Clinical Immunology, Berlin, Germany, 11Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Rheumatology Department, Lisboa, Portugal, 12Hospital Beatriz Ângelo, Division of Gastroenterology, Loures, Portugal, 13Unidade de Gastroenterologia of CHBM, Barreiro, Portugal, 14Humanitas University; Humanitas Clinical and Research Centre, Department of Biomedical Sciences, Milan, Italy, 15Academic Medical Center, Amsterdam, The Netherlands, 16Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Department of Gastroenterology, Tel-Aviv, Israel, 17Portuguese Institute of Oncology of Lisbon Francisco Gentil, EPE, Lisboa, Portugal, 18Hospital de Santa Maria, Department of Gastroenterology and Hepatology, Lisboa, Portugal, 19Faculty of Medicine, University of Porto, Centro Hospitalar São João, Gastroenterology Department, Porto, Portugal, 20Semmelweis University, First Department of Medicine, Budapest, Hungary, 21McGill University, MUHC, Montreal General Hospital, Division of Gastroenterology, Montreal, Canada

P546: Vedolizumab outcomes in real-world bio-naive ulcerative colitis and Crohn’s disease patients (EVOLVE) in Canada: Interim resultsECCO '18 Vienna
Year: 2018
Authors:

B. Bressler1*, A.-J. Greenup1, M. Bassel2, D. Stein3, M. Soni3, G. Radulescu4, C. Neish4, J.M. Khalid5, D. Demuth5

1St. Paul's Hospital, Vancouver, Canada, 2Evidera, St-Laurent, Canada, 3Evidera, London, UK, 4Takeda, Oakville, Canada, 5Takeda Development Centre Europe Ltd., London, UK

P547: Clinical effectiveness of vedolizumab: Interim analysis of the Swedish observational study on vedolizumab assessing effectiveness and healthcare resource utilisation in patients with ulcerative colitis (SVEAH UC)ECCO '18 Vienna
Year: 2018
Authors:

C. Eriksson1, S. Rundquist1*, V. Lykiardopoulos2, P. Karlén3, O. Grip4, C. Söderman5, S. Almer6, E. Hertervig7, J. Gunnarsson8, C. Malmgren9, J. Delin10, H. Strid11, M. Sjöberg12, D. Öberg13, D. Bergemalm1, R. Udumyan14, H. Hjortswang2, The SWIBREG SVEAH Study Group, J. Halfvarson1

1Faculty of Medicine and Health, Örebro University, Department of Gastroenterology, Örebro, Sweden, 2Linköping University, Department of Gastroenterology, Linköping, Sweden, 3Danderyd Hospital, Department of Internal Medicine, Stockholm, Sweden, 4Skåne University Hospital, Department of Gastroenterology, Malmö, Sweden, 5St Göran Hospital, Department of Internal Medicine, Stockholm, Sweden, 6Karolinska Institute, Department of Medicine, Stockholm, Sweden, 7Skåne University Hospital, Department of Gastroenterology, Lund, Sweden, 8Kungsbacka Hospital, Department of Internal Medicine, Kungsbacka, Sweden, 9Takeda Pharma AB, Solna, Sweden, 10Ersta Hospital, Department of Gastroenterology, Stockholm, Sweden, 11Södra Älvsborgs Hospital, Department of Internal Medicine, Borås, Sweden, 12Skaraborgs Hospital, Department of Internal Medicine, Lidköping, Sweden, 13Sunderby Hospital, Department of Internal Medicine, Sunderbyn, Sweden, 14Örebro University, Clinical Epidemiology and Biostatistics, Örebro, Sweden