¹John Radcliffe Hospital, Translational Gastroenterology Unit, Oxford, UK, ²Big Data Institute, Oxford, UK, ³University of Oxford, Psychiatry Department, Oxford, UK, ⁴University of Oxford, Nuffield Department of Population Health, Oxford, UK, ⁵University of Oxford, Centre for Statistics in Medicine, Oxford, UK

¹Alfred Health, Pharmacy, Melbourne, Australia, ²Alfred Health, Gastroenterology, Melbourne, Australia, ³Monash University, Centre for the Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Melbourne, Australia, ⁴Monash University, Department of Medicine, Melbourne, Australia

¹Azienda Ospedaliera Villa Sofia-Cervello, Emergency and General Surgery, Palermo, Italy, ²P.L Shupyk National Medical Academy Of Postgraduate Education, Kyiv, Ukraine

¹IWK Health Centre, Pediatric Gastroenterology and Nutrition, Halifax, Canada, ²Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Canada

¹KU Leuven, Leuven, Belgium, ²UZ Leuven, Leuven, Belgium

Yonsei University College of Medicine, Department of Internal Medicine and Institute of Gastroenterology, Seoul, South Korea

Erasmus MC, Gastroenterology and Hepatology, Rotterdam, The Netherlands

Akitsu Prefectural Hospital, Hiroshima, Japan

Wroclaw Medical University, Clinical Pharmacology, Wroclaw, Poland

¹Humanitas Research Hospital, Rozzano, Milan, Italy, ²Cajuru University Hospital, Catholic University of Paraná, Curitiba, Brazil, ³Geneva University Hospital, Geneva, Switzerland, ⁴Geneva University Hospital, Geneva, Switzerland

¹McMaster University, Gastroenterology, Hamilton, ON, Canada, ²Mount Sinai Hospital, Toronto, Canada

¹McGill University Health Centre, Department of Gastroenterology, Montreal, Canada, ²Geneva's University Hospitals and University of Geneva, Division of Gastroenterology and Hepatology, Geneva, Switzerland

Galway University Hospital, Gastroenterology, Galway, Ireland

¹Nancy University Hospital, Department of Gastroenterology, Vandoeuvre-lès-Nancy, France, ²Imelda GI Clinical Research Centre, Department of Gastroenterology, Bonheiden, Belgium, ³Nancy University Hospital, Clinical Research Support Facility PARC, Vandoeuvre-lès-Nancy, France

¹All India Institute of Medical Sciences, Department of Gastroenterology and Human Nutrition, New Delhi, India, ²All India Institute of Medical Sciences, Gastroenterology, New Delhi, India, ³All India Institute of Medical Sciences, Department of Biostatistics, New Delhi, India

Kagawa Prefectural Central Hospital, Department of Gastroenterology, Takamatsu, Kagawa, Japan

¹Centre Hospitalier Universitaire Vaudois, Gastroenterology and Hepatology, Lausanne, Switzerland, ²University Hospital Zurich, Zurich, Switzerland, ³Helsana Health Insurance, Zurich, Switzerland

¹Leiden University Medical Center, Gastroenterology and Hepatology, Leiden, The Netherlands, ²HagaZiekenhuis, Gastroenterology and Hepatology, The Hague, The Netherlands, ³Leiden University Medical Center, Medical Psychology, Leiden, The Netherlands, ⁴Leiden University Medical Center, Medical Statistics, Leiden, The Netherlands

¹St Mark's Hospital, Colorectal Surgery, London, UK, ²Patient representative, London, UK, ³Patient Representative, Liverpool, UK, ⁴Patient Representative, London, UK, ⁵Sheffield Teaching Hospitals NHS Trust, Northern General Hospital, Department of Colorectal Surgery, Sheffield, UK, ⁶University Hospital South Manchester, Department of Colorectal Surgery, Manchester, UK, ⁷St Mark’s Hospital, IBD/Physiology, London, UK, ⁸Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Department of Colorectal Surgery, Cambridge, UK

¹University Hospital Heraklion, Department of Gastroenterology, Heraklion, Greece, ²University of Athens, School of Medicine, Department of Basic Medical Science, Laboratory of Biology, Athens, Greece