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P758: Elevation in ribosomal and cell cycle gene transcription in macroscopically normal colonic tissue from Icelandic patients with ulcerative colitisECCO '17 Barcelona
Year: 2017
Authors:

Vinayaga-Pavan M.*1, Frampton M.2, Pontikos N.3, Levine A.2, Smith P.2, Jonasson J.4, Björnsson E.4, Segal A.2, Smith A.1

1Eastman Dental Institute, University College London, London, United Kingdom 2Molecular Medicine, Division of Medicine, University College London, London, United Kingdom 3UCL Genetics Institute, London, United Kingdom 4Landspitali University Hospital, Reykjavik, Iceland

P759: MiRNA expression patterns in colon of active and inactive ulcerative colitisECCO '17 Barcelona
Year: 2017
Authors:

Juzenas S.*1, Skieceviciene J.1, Salteniene V.1, Kupcinskas J.1,2, Hemmrich-Stanisak G.3, Du Z.3, Hübenthal M.3, Kiudelis G.1,2, Jonaitis L.1,2, Franke A.3, Kupcinskas L.1,2

1Lithuanian University of Heath Sciences, Institute for Digestive Research, Kaunas, Lithuania 2Lithuanian University of Heath Sciences, Department of Gastroenterology, Kaunas, Lithuania 3Christian-Albrechts-University Kiel, Institute for Clinical Molecular Biology, Kiel, Germany

P760: microRNA expression profiling of inflammatory bowel diseaseECCO '17 Barcelona
Year: 2017
Authors:

Sibia C.F.1, Silva R.P.L.*2, Ariede J.R.3, Severino F.E.2, Farinelli E.2, Renosto F.L.2, Sassaki L.Y.2, Reis P.P.2, Hossne R.S.2

1Faculdade de Medicina de Botucatu, Botucatu, São Paulo, Brazil 2Faculdade de Medicina de Botucatu, Botucatu, São Paulo, Brasil, Brazil 3Faculdade de Medicina de Botucatu, Botucatu, Brazil

P761: Gene expression differences between Crohn's disease aphthous ulcers and healthy Peyer's patches highlights potential treatment strategiesECCO '17 Barcelona
Year: 2017
Authors:

O'Brien C.*1,2, Patel H.3, Freeman T.4, Zhang K.5, Peng K.5, Pavli P.1,2

1Australian National University, Medical School, Canberra, ACT, Australia 2Canberra Hospital, Gastroenterology and Hepatology Unit, Canberra, ACT, Australia 3Australian National University, John Curtin School of Medical Research, Canberra, ACT, Australia 4University of Edinburgh, The Roslin Institute and Royal (Dick) School of Veterinary Studies, Edinburgh, United Kingdom 5Australian National University, Biological Research Facility, Canberra, ACT, Australia

P762: Gene expression profiling of immune adaptive response in the colonic mucosa from patients with ulcerative colitisECCO '17 Barcelona
Year: 2017
Authors:

Fonseca Camarillo G., Iturriaga Goyon E., Yamamoto Furusho J.K.

Instituto Nacional de Ciencias Médicas y Nutriciόn Salvador Zubiran, Inflammatory Bowel Disease Clinic. Department of Gastroenterology, Mexico City, Mexico

P763: Fucosyltransferase 2 non-secretor status in Crohn's disease: a prospective observational analysisECCO '17 Barcelona
Year: 2017
Authors:

Battat R.*1,2, Kopylov U.3, Afif W.1, Bessissow T.1, Byer J.4, Dionne S.1, Zelikovic E.4, Seidman E.1, Bitton A.1

1McGill University Health Centre, Gastroenterology, Montreal, Canada 2Jewish General Hospital, Gastroenterology, Montreal, Canada 3Sheba Medical Center Tel Hashomer and Sackler School of Medicine, Tel Aviv University, Gastroenterology, Tel Aviv, Israel 4McGill University, Medicine, Montreal, Canada

P764: Response to thiopurines is independent of ATG16L1 genotypeECCO '17 Barcelona
Year: 2017
Authors:

Verstockt B.*1,2, Matthias A.T.3, Strongili K.3, Cleynen I.4, Parkes M.3

1KU Leuven, Department of Clinical and Experimental Medicine, TARGID-IBD, Leuven, Belgium 2University of Cambridge, School of Clinical Medicine, Cambridge, Biomedical Campus, Department of Medicine and Cambridge Institute for Medical Research, Cambridge, United Kingdom 3University of Cambridge and Addenbrooke's Hospital, Gastroenterology Unit, Cambridge, United Kingdom 4KU Leuven, Laboratory of Complex Genetics, Department of Human Genetics, Leuven, Belgium

P765: Transcriptome of intestinal epithelial barrier genes in the colonic mucosa from patients with ulcerative colitisECCO '17 Barcelona
Year: 2017
Authors:

Fonseca Camarillo G., Iturriaga Goyon E., Yamamoto Furusho J.K.

Instituto Nacional de Ciencias Médicas y Nutriciόn Salvador Zubiran, Inflammatory Bowel Disease Clinic. Department of Gastroenterology, Mexico City, Mexico

P766: Combination therapy of fresh fecal microbial transplantation and antibiotics for ulcerative colitisECCO '17 Barcelona
Year: 2017
Authors:

Ishikawa D., Takahashi M., Haga K., Shibuya T., Osada T., Watanabe S.

Juntendo University, Department of Gastroenterology, Tokyo, Japan

P767: The FIT trial: anti-inflammatory dietary intervention effects on the intestinal microbiotaECCO '17 Barcelona
Year: 2017
Authors:

Sabino J.*1, Vieira-Silva S.2,3, Machiels K.4, Joossens M.2,3,5, Falony G.2,3, Ferrante M.4, Van Assche G.4, Van Der Merwe S.6, Matthys C.7, Raes J.2,3, Vermeire S.4

1University of Leuven, Translational Research Center for Gastrointestinal Disorders (TARGID), Leuven, Belgium 2REGA institute, KU Leuven, Department of Microbiology and Immunology, Leuven, Belgium 3Vlaams Instituut voor Biotechnologie (VIB), Center for the Biology of Disease, Leuven, Belgium 4KU Leuven, Department of Clinical and Experimental Medicine, Translational Research Center for GastroIntestinal Disorders (TARGID), Leuven, Belgium 5VUB, Department of Microbiology, Brussels, Belgium 6University Hospitals of Leuven, Department of Hepatology, Leuven, Belgium 7University of Leuven, Leuven, Belgium

P768: Co-housing DSS treated mice with healthy mice results in faster recovery and normalization of the intestinal microbiotaECCO '17 Barcelona
Year: 2017
Authors:

Spalinger M.*1, Gottier C.1, Hering L.1, Lang S.1, Rogler G.1,2, Scharl M.1,2

1University Hospital Zurich, Division of Gastroenterology and Hepatology, Zürich, Switzerland 2University of Zurich, Zurich Center for Integrative Human Physiology, Zürich, Switzerland

P769: In Crohn's disease, an aggressive disease course is related to an increased abundancy of proteobacteria: a seven year follow up studyECCO '17 Barcelona
Year: 2017
Authors:

Vester-Andersen M.K.*1,2, Mirsepasi-Lauridsen H.C.3, Vind I.1, Prosberg M.V.1, Mortensen C.O.4, Träger C.4, Thorkilgaard T.4, Skovsen K.4, Sørensen N.5, Krogfeldt K.A.3, Bendtsen F.1, Petersen A.M.1,6

1Hvidovre Hospital, University of Copenhagen, Denmark, Gastrounit Medical division, Hvidovre, Denmark 2Zealand University Hospital, Køge, Denmark, Department of Medical Gastroenterology, Køge, Denmark 3Statens Serum Institut, Department of Microbiology and Infection Control, Copenhagen, Denmark 4Herlev and Gentofte Hospital, University of Copenhagen, Denmark, Department of Gastroenterology, Herlev, Denmark 5Department of Clinical-Microbiomics A/S Ole Maaløesvej 3, Copenhagen, Copenhagen, Denmark 6Hvidovre Hospital, University of Copenhagen, Denmark, Department of Clinical Microbiology, Hvidovre, Denmark

P770: First analysis from UK IBD Twin Biobank; 16S rRNA gene sequencing identifies reduced diversity in IBD and bacterial taxa associated with diseaseECCO '17 Barcelona
Year: 2017
Authors:

McDonald J.1, Gordon H.*2, Blad W.3, Orchard T.4, Marchesi J.1, Harbord M.3

1Imperial College London, Marchesi Laboratory, London, United Kingdom 2Royal London Hospital, Gastroenterology, London, United Kingdom 3Chelsea and Westminster Hospital, Gastroenterology, London, United Kingdom 4St Mary's Hospital, Gastroenterology, London, United Kingdom

P771: The recombinant NZ9000SHD-5 attenuates the inflammation and mucosal lesions in dextran sodium sulfate-induced colitisECCO '17 Barcelona
Year: 2017
Authors:

Zeng L., Chen Y.

Nanfang Hospital, Department of Gastroenterology, Guangzhou, China

P772: The presence of adherent-invasive Escherichia coli strains on the surgical specimen is a predictor of severe endoscopic postoperative recurrence in Crohn's diseaseECCO '17 Barcelona
Year: 2017
Authors:

Barnich N.*1, Buisson A.2, Auzolle C.3, Rodrigues M.2, Stefanescu C.3, Nancey S.4, Desreumaux P.5, Marteau P.3, Fumery M.6, Sokol H.3, Treton X.3, Seksik P.3, Allez M.3

1Université d'Auvergne, UMR Inserm U1071, Clermont-Ferrand, France 2Université d'Auvergne, Clermont-Ferrand, France 3APHP, Paris, France 4Université Lyon, Lyon, France 5Université Lille, Lille, France 6Université Amiens, Amiens, France

P773: Post-operative Crohn's disease recurrence is associated with specific changes in the faecal microbiome – potential pathogenic and protective rolesECCO '17 Barcelona
Year: 2017
Authors:

Hamilton A.L.*1,2, Kamm M.A.1,2, Teo S.-M.3, De Cruz P.1,2,4, Wright E.K.5, Feng H.6,7, Ritchie K.J.2, Kirkwood C.D.6, Inouye M.3

1University of Melbourne, Department of Medicine, Melbourne, Australia 2St Vincent's Hospital, Department of Gastroenterology, Melbourne, Australia 3The University of Melbourne, Centre for Systems Genomics, School of BioSciences, Melbourne, Australia 4Austin Health, Department of Gastroenterology, Melbourne, Australia 5St Vincent's Hospital & University of Melbourne, Department of Gastroenterology, Melbourne, Australia 6Murdoch Children's Research Institute, Enteric Virus Research Group, Melbourne, Australia 7Institute of Digestive Disease and Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong SAR, Hong Kong

P774: Metagenomics and metabolomics of patients with inflammatory bowel disease and their unaffected relativesECCO '17 Barcelona
Year: 2017
Authors:

Vancamelbeke M.*1, Sabino J.1, Deroover L.1, Vandermeulen G.1, Luypaerts A.1, Ferrante M.1,2, Falony G.3, Vieira-Silva S.3, Verbeke K.1, Raes J.3, Cleynen I.4, Vermeire S.1,2

1KU Leuven, Department of Clinical and Experimental Medicine, Translational Research Center for Gastrointestinal Disorders, Leuven, Belgium 2University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium 3Rega Institute for Medical Research, VIB, KU Leuven, Department of Microbiology and Immunology, Laboratory of Molecular Bacteriology, Leuven, Belgium 4KU Leuven, Department of Human Genetics, Laboratory for Complex Genetics, Leuven, Belgium

P775: Fibre intake is associated with microbiome changes in pediatric Crohn's disease patients following remission induction with exclusive enteral nutritionECCO '17 Barcelona
Year: 2017
Authors:

MacLellan A.*1, Connors J.2, MacIntyre B.2, Douglas G.3, Dunn K.A.4, Bielawski J.P.4, Noble A.2, Mahdi G.2, Rashid M.2, Otley A.R.2, Cahill L.5, Langille M.G.3, Van Limbergen J.6

1IWK Health Centre - Dalhousie University, Pediatric Gastroenterology & Nutrition, Halifax, Canada 2IWK Health Centre, Halifax, Canada 3Dalhousie University, Pharmacology, Halifax, Canada 4Dalhousie University, Biology, Halifax, Canada 5Dalhousie University, Community Health and Epidemiology, Halifax, Canada 6IWK Health Centre - Dalhousie University, Pediatric Gastroenterology, Halifax, Canada

P776: Dysbiosis in Nlrp6/Asc-deficient mice does not result from inflammasome deficiencyECCO '17 Barcelona
Year: 2017
Authors:

Mamantopoulos M.1,2, Ronchi F.3, Van Hauwermeiren F.2,4, Vieira-Silva S.5,6, Yilmaz B.3, Martens L.2,4, Saeys Y.2,4, Drexler S.7, Yazdi A.8, Raes J.5,6, Lamkanfi M.2,4, McCoy K.3, Wullaert A.*2,4

1Ghent University, Department of Internal Medicine, Ghent, Belgium 2VIB Inflammation Research Center, Ghent, Belgium 3Universitätsklinik Bern Inselspital, Department of Gastroenterology, Bern, Switzerland 4Ghent University, Ghent, Belgium 5KU Leuven, Rega Institute, Department of Microbiology and Immunobiology, Leuven, Belgium 6VIB Center for the Biology of Disease, Leuven, Belgium 7Biozentrum, University of Basel, Basel, Switzerland 8Department of Dermatology, University of Tübingen, Tübingen, Germany

P777: Ursodeoxycholic acid and its taurine/glycine conjugated species reduce colitogenic dysbiosis and equally suppress experimental colitis in miceECCO '17 Barcelona
Year: 2017
Authors:

Van den Bossche L.*1, Hindryckx P.1, Devisscher L.1, Devriese S.1, Van Welden S.1, Holvoet T.1, Vilchez-Vargas R.2, Vital M.3, Pieper D.H.3, Vanden Bussche J.4, Vanhaecke L.4, Van de Wiele T.2, De Vos M.1, Laukens D.1

1Ghent University, Department of gastroenterology, Ghent, Belgium 2Ghent University, Center for Microbial Ecology and Technology, Ghent, Belgium 3Helmholtz Centre for Infection Research, Department of Medical Microbiology, Braunschweig, Germany 4Ghent University, Department of Veterinary Public Health and Food Safety, Ghent, Belgium