¹Azienda Ospedaliera Villa Sofia-Cervello, Emergency and General Surgery, Palermo, Italy, ²Maria Skłodowska-Curie Memorial Institute of Oncology Cancer Centre, Krakow, Poland

¹CHU Strasbourg, Department of Gastroenterology and Hepatology, Strasbourg, France, ²CHU Nancy, Department of Gastroenterology and Hepatology, Vandoeuvre-Lès-Nancy, France, ³CHRU Lille, Department of Gastroenterology, Lille, France, ⁴CHU Beaujon, Department of Gastroenterology, Clichy, France, ⁵CHU Saint-Antoine, Department of Gastroenterology, Paris, France, ⁶CHU Pontchaillou, Department of Gastroenterology, Rennes, France, ⁷CHU Nimes, Department of Gastroenterology and Hepatology, Nimes, France, ⁸CHU Bordeaux, Department of Gastroenterology, Bordeaux, France, ⁹CHU Bicêtre, Department of Gastroenterology, Le Kremlin-Bicêtre, France, ¹⁰CHU Montpellier Saint Eloi Hospital, Department of Gastroenterology, Montpellier, France, ¹¹CHU Liège, Sart Tilman, Department of Gastroenterology, Liège, Belgium, ¹²CHU Marseille, Department of Gastroenterology and Hepatology, Marseille, France, ¹³CHU Nantes, Department of Gastroenterology and Hepatology, Nantes, France, ¹⁴Hospital Edouard Herriot, Department of Gastroenterology and Hepatology, Lyon, France, ¹⁵Archet 2 Hospital, Department of Gastroenterology, Nice, France, ¹⁶Cochin Hospital, Department of Gastroenterology, Paris, France, ¹⁷Rouen Hospital, Department of Gastroenterology and Hepatology, Rouen, France, ¹⁸CHU Besancon, Department of Gastroenterology and Hepatology, Besançon, France, ¹⁹Hospital Cote de Nacre, Department of Gastroenterology, Caen Cede, France, ²⁰Amiens University Hospital, Department of Gastroenterology, Amiens, France, ²¹CHU Clermont-Ferrand, Department of Gastroenterology and Hepatology, Clermont Ferrand, France, ²²CHU Nancy, Department of Gastroenterology and Hepatology, Nancy, France, ²³CHU Strasbourg, Strasbourg, France, ²⁴Henri Mondor Hospital, Gastroenterology, Creteil, France

¹St Mark's Hospital, Colorectal Surgery, London, UK, ²St Mark's Hospital, Gastrointestinal Imaging, London, UK, ³St Mark's Hospital, IBD/Physiology, London, UK

¹Assaf Harofeh Medical Center, The Kamila Gonczarowski institute of Gastroenterology Assaf Harofeh Medical Center, Zerifin, Israel, ²Tel Aviv university Sackler school of medicin, internal medicine, Tel aviv, Israel, ³Tel Aviv university Sackler school of medicin, internal medicine, Tel Aviv, Israel

¹Rabin Medical Center, Beilinson Hospital, Department of Gastroenterology, Petah Tikva, Israel, ²Tel Aviv University, Sackler Faculty of Medicine, Tel Aviv, Israel, ³Tel Aviv Sourasky Medical Center, Genetic Institute, Tel Aviv, Israel, ⁴Tel Aviv Sourasky Medical Center, Department of Gastroenterology and Liver Diseases, Tel Aviv, Israel, ⁵Tel Aviv University, Israel, Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv, Israel

¹Humanitas Clinical and Research Institute, Rozzano, Italy, ²University of Nancy, Nancy, France

¹Medical University of Vienna, Department of Internal Medicine III, Vienna, Austria, ²Hospital Barmherzige Brüder St. Veit an der Glan, Department of Internal Medicine, St. Veit an der Glan, Austria, ³Darmpraxis Salzburg, Salzburg, Austria, ⁴Medical University of Graz, Department of Gastroenterology and Hepatology, Graz, Austria, ⁵Hospital Wels-Grieskirchen, Department of Internal Medicine I, Wels, Austria, ⁶Medical University of Innsbruck, Department of Internal Medicine I, Innsbruck, Austria, ⁷Hospital Rudolfstiftung, Department of Internal Medicine IV, Vienna, Austria, ⁸Hospital Oberpullendorf, Department of Internal Medicine, Oberpullendorf, Austria, ⁹Universitätsklinikum St. Pölten, Department of Internal Medicine II, St. Pölten, Austria, ¹⁰Hospital Wels-Grieskirchen, Department of Internal Medicine V, Grieskirchen, Austria, ¹¹Hospital Hall in Tirol, Department of Internal Medicine, Hall in Tirol, Austria, ¹²Hospital Wiener Neustadt, Department of Internal Medicine I, Wiener Neustadt, Austria, ¹³Hartmannspital, Department of Internal Medicine, Vienna, Austria, ¹⁴Hanusch Hospital, Department of Internal Medicine, Vienna, Austria, ¹⁵Hospital Elisabethinen Linz, Department of Internal Medicine IV, Linz, Austria, ¹⁶Hospital Barmherzige Brüder Salzburg, Department of Internal Medicine, Salzburg, Austria, ¹⁷Hospital Feldkirch, Department of Internal Medicine, Feldkirch, Austria, ¹⁸Hospital Barmherzige Brüder Graz, Department of Internal Medicine, Graz, Austria, ¹⁹Medical University of Vienna, Department of Epidemiology, Vienna, Austria

¹University of Ulsan College of Medicine, Asan Medical Center, Department of Gastroenterology, Seoul, South Korea, ²University of Ulsan College of Medicine, Asan Medical Center, Department of Clinical Epidemiology and Biostatistics, Seoul, South Korea, ³University of Ulsan College of Medicine, Asan Medical Center, Inflammatory Bowel Disease Center, Seoul, South Korea

¹University of Greenwich, Faculty of Education and Health, London, UK, ²Bart's Health NHS Trust, Academic Research Centre, London, UK, ³King's College London, Florence Nightingale School of Nursing and Midwifery, London, UK, ⁴Stats Consultancy, Amersham, UK

¹Hospital Central do Funchal, Gastroenterology, Funchal, Portugal, ²Hospital Central do Funchal, Clinical Pathology, Funchal, Portugal

Faculdade de Medicina da USP, Gastroenterology, São Paulo, Brazil

¹Singapore General Hospital, Pharmacy, Singapore, Singapore, ²Singapore General Hospital, Department of Gastroenterology and Hepatology, Singapore, Singapore, ³Duke-NUS Medical School, Singapore, Singapore

¹Hospital de Braga, Gastroenterology, Braga, Portugal, ²School of Health Sciences, University of Minho, Braga, Portugal

¹TopiVert Pharma Ltd., London, UK, ²Oxford University Hospitals Trust, Translational Gastroenterology Unit, Oxford, UK

¹John Radcliffe Hospital, Translational Gastroenterology Unit, Oxford, UK, ²University of Oxford, Nuffield Department of Population Health, Oxford, UK, ³Big Data Institute, Oxford, UK, ⁴Mathematical Institute, Oxford, UK, ⁵University of Oxford, Psychiatry Department, Oxford, UK, ⁶Weatherall Institute of Molecular Medicine, Oxford, UK, ⁷University of Oxford, Centre for Statistics in Medicine, Oxford, UK

¹MassGeneral Hospital for Children, Pediatric Gastroenterology, Boston, USA, ²Harvard Medical School, Boston, USA, ³Cincinnati Children's Hospital, Cincinnati, USA, ⁴Children’s Mercy Hospital, Kansas City, USA, ⁵University of Texas-Southwestern/Children's Medical Center, Dallas, USA, ⁶The Children’s Hospital at Montefiore, Bronx, USA, ⁷Mayo Clinic-Children’s Center, Rochester, USA, ⁸Takeda Pharmaceuticals USA, Deerfield, USA, ⁹University of Vermont College of Medicine, Burlington, USA

¹Sapienza University, Department of Internal Medicine and Medical Specialties, Rome, Italy, Rome, Italy, ²Cristo Re, Hospital, Internal Medicine, “Cristo Re” Hospital, Rome, Italy, Rome, Italy

¹Stanford University School of Medicine, Gastroenterology and Hepatology, Stanford, California, USA, ²Icahn School of Medicine at Mount Sinai, Gastroenterology, New York, New York, USA, ³Frederiksberg Hospital, Clinical Epidemiology, Frederiksberg, Denmark, ⁴Montefiore Medical Center, Gastroenterology, Bronx, USA

¹La Fe University and Polytechnic Hospital and CIBER-EHD, Department of Gastroenterology, Valencia, Spain, ²La Fe University and Polytechnic hospital of Valencia, Department of Gastroenterology and Hepatology, Valencia, Spain, ³University Clinic Hospital of Valencia, Department of Gastroenterology and Hepatology, Valencia, Spain, ⁴Hospital de Sagunto (Sagunto), Department of Gastroenterology, Valencia, Spain

¹Hospital for Sick Children, University of Toronto, Toronto, Canada, ²University of Calgary, Medicine, Calgary, Canada, ³Ludwig-Maximilians-University Munich, Munich, Germany, ⁴Center of Endoscopy, Starnberg, Germany