¹University of California, San Diego, Division of Gastroenterology, La Jolla, USA, ²Robarts Clinical Trials, La Jolla, USA, ³University of California, Division of Gastroenterology, La Jolla, USA, ⁴Prometheus Laboratories Inc., La Jolla, USA

¹Ospedale Sacro Cuore Don Calabria, IBD Unit, Negrar, Italy, ²Ospedale Sacro Cuore Don Calabria, Radiology, Negrar, Italy

¹Catholic University of Sacred Heart, Internal Medicine Department, Gastroenterology Division, Rome, Italy, ²Case Western Reserve University, Pathology, Cleveland, USA

Yokkaichi Hazu Medical Centre, Inflammatory Bowel Disease Centre, Yokkaichi, Japan

¹The Ohio State University – Wexner Medical Center, Columbus, USA, ²Truven Health Analytics, an IBM Company, Cambridge, USA, ³AbbVie Inc., North Chicago, USA

¹Policlinico San Martino, University of Genoa, Department of Internal Medicine, Genoa, Italy, ²Prometheus Laboratories, Department of Research and Development, San Diego, California, USA, ³University of Padua, Department of Surgery, Oncology and Gastroenterology, Padova, Italy

¹Faculty of Medicine, University of Porto,, Department of Biomedicine, Unit of Pharmacology and Therapeutics, Porto, Portugal, ²Centro Hospitalar São João, Gastroenterology Department, Porto, Portugal, ³Centre for Drug Discovery and Innovative Medicines, University of Porto, Porto, Portugal, ⁴Faculty of Medicine, Centro Hospitalar Sao Joao, Department of Pathology, Porto, Portugal, ⁵Faculty of Medicine, University of Lisbon, Institute of Pathology, Lisbon, Portugal, ⁶Centro Hospitalar São Joao, Department of Gastroenterology, Porto, Portugal, ⁷Hospital da Senhora da Oliveira, Department of Gastroenterology, Guimarães, Portugal, ⁸Centro Hospitalar do Algarve, Gastroenterology Department, Portimão, Portugal, ⁹Centro Hospitalar do Porto, Department of Gastroenterology, Porto, Portugal, ¹⁰Hospital Garcia de Orta, Department of Gastroenterology, Almada, Portugal, ¹¹Centro Hospitalar do Algarve, Department of Gastroenterology, Faro, Portugal, ¹²Divino Espírito Santo Hospital, Department of Gastroenterology, Ponta Delgada, Portugal, ¹³Instituto Português do Oncologia de Lisboa, Department of Gastroenterology, Lisboa, Portugal, ¹⁴Centro hospitalar e Universitário de Coimbra, Department of Gastroenterology, Coimbra, Portugal, ¹⁵Centro Hospitalar Tondela-Viseu, Department of Gastroenterology, Viseu, Portugal, ¹⁶Hospital de Braga, Department of Gastroenterology, Braga, Portugal, ¹⁷Hospital Fernando da Fonseca, Department of Gastroenterology, Amadora, Portugal, ¹⁸Instituto Português de Oncologia de Lisboa,, Gastroenterology Department, Lisboa, Portugal, ¹⁹Centro Hospitalar Lisboa Ocidental, Department of Gastroenterology, Lisbon, Portugal, ²⁰Hospital Beatriz Angelo, Department of Gastroenterology, Loures, Portugal, ²¹Faculty of Medicine, University of Porto, Health Information and Decision Sciences Department, Porto, Portugal, ²²Center for Health Technology and Services Research, Porto, Portugal, ²³University Hospital of KU Leuven and UZ Gent, Department of Pathology, Leuven, Belgium, ²⁴Instituto de Investigação e Inovação na Saúde (I3S), Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal

¹Kyungpook National University Hospital, Kyungpook National University School of Medicine, Division of Gastroenterology, Department of Internal Medicine, Daegu, South Korea, ²Kyungpook National University Medical Center, Kyungpook National University School of Medicine, Division of Gastroenterology, Department of Internal Medicine, Daegu, South Korea

¹Kyoto Prefectural University of Medicine, Molecular Gastroenterology and Hepatology, Kyoto, Japan, ²Murakami Memorial Hospital, Asahi University, Department of Gastroenterology, Gifu, Japan

¹The Royal Wolverhampton NHS Trust, Department of Clinical Chemistry, Wolverhampton, UK, ²The Royal Wolverhampton NHS Trust, Department of Gastroenterology, Wolverhampton, UK

¹Hospital Universitario de Canarias, Gastroenterology, La Laguna, Spain, ²Hospital Universitario de Canarias, Pathology, La Laguna, Spain, ³Hospital Universitario de Canarias, Research Unit, La Laguna, Spain, ⁴Universidad de La Laguna, La Laguna, Spain

¹Hospital Universitario de La Princesa, Gastroenterology Unit, Madrid, Spain, ²Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain, ³Universidad Autónoma de Madrid, Madrid, Spain, ⁴Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain, ⁵Hospital de Galdakao-Usansolo, Gastroenterology Unit, Vizcaya, Spain, ⁶Hospital Universitario de Gran Canaria Doctor Negrín, Gastroenterology Unit, Las Palmas de Gran Canaria, Spain, ⁷Consorci Sanitari Terrassa, Gastroenterology Unit, Tarrasa, Spain, ⁸Hospital San Pedro, Gastroenterology Unit, Logroño, Spain, ⁹Hospital Clínico Universitario de Santiago, Gastroenterology Unit, Santiago de Compostela, Spain, ¹⁰Hospital Universitario Reina Sofía, Gastroenterology Unit, Córdoba, Spain, ¹¹IMIBIC, Córdoba, Spain, ¹²Hospital Universitario Son Espases, Gastroenterology Unit, Palma de Mallorca, Spain, ¹³Hospital Clínico Universitario Lozano Blesa, Gastroenterology Unit, Zaragoza, Spain, ¹⁴ISS Aragón, Zaragoza, Spain, ¹⁵Hospital General Universitario de Ciudad Real, Gastroenterology Unit, Ciudad Real, Spain, ¹⁶Hospital Universitario y Politécnico de La Fe, Gastroenterology Unit, Valencia, Spain, ¹⁷Hospital Universitario Central de Asturias, Gastroenterology Unit, Oviedo, Spain, ¹⁸Hospital Universitario de Marqués de Valdecilla, Gastroenterology Unit, Santander, Spain, ¹⁹Hospital San Pedro de Alcántara, Gastroenterology Unit, Cáceres, Spain, ²⁰Complejo Hospitalario de Navarra, Gastroenterology Unit, Pamplona, Spain, ²¹Hospital Universitario de Burgos, Gastroenterology Unit, Burgos, Spain, ²²Hospital General Universitario Morales Meseguer, Gastroenterology Unit, Murcia, Spain, ²³Universidad Autónoma de Madrid, Preventive Medicine and Public Health, Madrid, Spain, ²⁴IdiPAZ, Madrid, Spain, ²⁵Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain

¹St Mark's Hospital, Colorectal Surgery, London, UK, ²St Mark's Hospital, Gastrointestinal Imaging, London, UK, ³St Mark's Hospital, IBD/Physiology, London, UK

¹Tallaght Hospital, Gastroenterology, Dublin 24, Ireland, ²Talllaght Hospital, Dublin, Ireland, ³Talllaght Hospital, Gastroenterology, Dublin, Ireland, ⁴Adelaide and Meath Hospital, Dublin, Incorporating The National Children's Hospital, Department of Gastroenterology, Dublin, Ireland, ⁵Trinity College Dublin, Dublin, Ireland, ⁶Adelaide and Meath Hospital, Dublin, Incorporating The National Children's Hospital, Department of Radiology, Dublin, Ireland

¹St Vincent's Hospital, Department of Gastroenterology, Melbourne, Australia, ²The University of Melbourne, Parkville, Australia, ³University of Calgary, Department of Gastroenterology, Calgary, Canada

¹King's College London, Florence Nightingale School of Nursing and Midwifery, London, UK, ²St Mark's Hospital, Harrow, London, UK, ³Guy's and St Thomas' NHS Foundation Trust, Department of Gastroenterology, London, UK, ⁴University College Hospital, Gi Division, London, UK, ⁵Queen Mary University London, London, UK, ⁶Queen Mary University London, Pragmatic Clinical Trials Unit, London, UK, ⁷Crohn's and Colitis UK, Department of Policy, Public Affairs, and Research, St Albans, UK, ⁸Patient representative, London, UK, ⁹University of Greenwich, Faculty of Education and Health, London, UK, ¹⁰Bart's Health NHS Trust, Academic Research Centre, London, UK

¹John Radcliffe Hospital, Translational Gastroenterology Unit, Oxford, UK, ²Mathematical Institute, Oxford, UK, ³Big Data Institute, Oxford, UK, ⁴University of Oxford, Psychiatry Department, Oxford, UK, ⁵University of Oxford, Nuffield Department of Population Health, Oxford, UK, ⁶University of Oxford, Centre for Statistics in Medicine, Oxford, UK

Instituto Português de Oncologia de Lisboa, Francisco Gentil, Lisboa, Portugal

Tokyo Women's Medical University, Institute of Gastroenterology, Tokyo, Japan

¹Nordic Bioscience, Biomarker and Research, Herlev, Denmark, ²Odense University Hospital, Kerteminde, Denmark, ³Lillebaelt Hospital Vejle, Internal Medicine, Section of Gastroenterology, Vejle, Denmark