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P106: Bifidobacterium longum subsp. longum microbiota-secreted bioactive peptide as a novel immunomodulatory compound in the human gastrointestinal tractECCO '18 Vienna
Year: 2018
Authors:

S. Fernández Tomé1,2,3*, A. Montalbán-Arqués1,2,3, A. Díaz-Guerra1,2,3, J.M. Galván Román2,4, A.C. Marín1,2,3, I. Mora-Gutiérrez1,2,3, C. Santander1,2,3,5, B. Sánchez6, M. Chaparro1,2,3,5, J.P. Gisbert1,2,3,5, D. Bernardo1,2,3

1Hospital Universitario de La Princesa, Gastroenterology Unit, Madrid, Spain, 2Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain, 3Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain, 4Hospital Universitario de La Princesa, Immunology Unit, Madrid, Spain, 5Universidad Autónoma de Madrid, Madrid, Spain, 6Instituto de Productos Lácteos de Asturias, Consejo Superior de Investigaciones Científicas (IPLA-CSIC), Department of Microbiology and Biochemistry of Dairy Products, Villaviciosa, Spain

P107: MicroRNA signatures can differentiate the inflamed colonic mucosa from non-inflamed mucosa in ulcerative colitis patientsECCO '18 Vienna
Year: 2018
Authors:

S. Valmiki1*, V. Ahuja2, J. Paul1, R. Ranjha1, R. Ranjha1

1Jawaharlal Nehru University, School of Life Sciences, New Delhi, India, 2All India Institute of Medical Sciences, Department of Gastroenterology, New Delhi, India

P108: Differential expression in colitis-associated cancer compared with Crohn’s disease and ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

M. Sehn1, S. Elezkurtaj2, D. Cardoso da Silva3, B. Siegmund4, M. Kreis1, C. Holmer1, M. Hummel5, J. Gröne6, M. Schumann3*

1Charite - University Hospital Berlin, Department of Surgery, Berlin, Germany, 2Charité university medicine, Pathology, Berlin, Germany, 3Charité university medicine, Gastroenterology, Berlin, Germany, 4Charité - University Hospital Berlin, Campus Benjamin Franklin, Department of Gastroenterology and Medicine I, Berlin, Germany, 5Charité university medicine, Institute of Molecular Pathology, Berlin, Germany, 6DRK Klinikum, Department of General and Visceral Surgery, Bremen, Germany

P109: Rifaximin and Saccharomyces boulardii increase stress resilience in TNBS-induced colitisECCO '18 Vienna
Year: 2018
Authors:

P. Konturek1*, Y. Zopf2, W. Dieterich2, S. Wirtz3, M.F. Neurath2, T. Brzozowski4

1Thuringia Clinic, Department of Medicine, Saalfeld, Germany, 2University Erlangen-Nuremberg, Department of Medicine, Erlangen, Germany, 3University Erlangen-Nuremberg, Department of Medicine, Erlangen, Ghana, 4University Cracow, Department of Physiology, Cracow, Poland

P110: TIGIT expression identifies circulating CD38+ effector T cells with immune regulatory properties whose frequencies at diagnosis predict disease course of paediatric IBD patientsECCO '18 Vienna
Year: 2018
Authors:

M. Joosse1*, C. Menckeberg1, L.F. de Ruiter1, H. Raatgeep1, L.A. van Berkel1, Y. Simons-Oosterhuis1, M. Joosse2, R.W. Hendriks2, R.M. Hoogenboezem3, T. Cupedo3, L. de Ridder4, J. Escher4, S. Veenbergen1, J.N. Samsom1

1Erasmus MC, Laboratory of Pediatrics, division Gastroenterology and Nutrition, Rotterdam, The Netherlands, 2Erasmus MC, Department of Pulmonology, Rotterdam, The Netherlands, 3Erasmus MC, Department of Hematology, Rotterdam, The Netherlands, 4Erasmus Medical Center Children's Hospital, Department of Paediatric Gastroenterology, Rotterdam, The Netherlands

P111: Extracellular Nicotinamide Phosphoribosyltransferase (eNAMPT): A possible new target in inflammatory bowel diseasesECCO '18 Vienna
Year: 2018
Authors:

C. Travelli1*, G. Colombo1, C. Porta1,2, F. Malavasi3, A.A. Genazzani1

1Università del Piemonte Orientale, Dipartimento di Scienze del Farmaco, Novara, Italy, 2University of Piemonte Orientale, Novara, Italy, 3University of Torino, Torino, Italy

P112: LXR-ABCA1 pathway: a therapeutic target in inflammatory bowel disease?ECCO '18 Vienna
Year: 2018
Authors:

J. Miranda-Bautista1*, J.A. Rodriguez-Feo1, B. Lopez Cauce1, M. Puerto1, J.M. Lara2, R. Bañares1, L. Menchén1

1Hospital General Universitario Gregorio Marañón, Servicio de Aparato Digestivo, Madrid, España, Gastroenterology Unit, Madrid, Spain, 2Hospital General Universitario Gregorio Marañón, Servicio de Aparato Digestivo, Madrid, España, Pathology, Madrid, Spain

P113: Effects of change in the gut microbiota on colon tumorigenesis in AOM-DSS modelECCO '18 Vienna
Year: 2018
Authors:

C.S. Eun*, D.S. Han, C.H. Park, A.R. Lee

Hanyang University Guri Hospital, Gastroenterology, Guri, South Korea

P114: Potassium competitive acid blocker, revaprazan, prevented indomethacin-induced intestinal permeability through tightening TJsECCO '18 Vienna
Year: 2018
Authors:

K.B. Hahm1*, J.M. Park2, Y.M. Han2

1CHA University, Gastroenterology, Seongnam, South Korea, 2CHA Cancer preventive Research center, Seongnam, South Korea

P115: Appendectomy and ulcerative colitis: role of innate immunity in the inflammatory response of the appendicular and colonic mucosaECCO '18 Vienna
Year: 2018
Authors:

L. Saadeh1*, I. Angriman1, M. Scarpa2, C. Mescoli3, G. Procida1, A. Kotsafti2, F. Cavallin2, M. Rugge4, R. Bardini1, I. Castagliuolo5, M. Scarpa2

1University of Padova, Department of Surgery, Oncology and Gastroenterology, Padova, Italy, 2IRCCS IOV Istituto Oncologico Veneto, Padova, Italy, 3Azienda Ospedaliera - Università di Padova, Padova, Italy, 4University of Padova, Department of Medicine, Padova, Italy, 5University of Padova, Department of Molecular Medicine, Padova, Italy

P116: A computable, causal biological network model suite for mechanistic evaluation of ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

J. Szostak, M. Talikka, M. Florian, R. Gadaleta*, M. Peitsch, J. Hoeng

Philip Morris International Research and Development, System Toxicology, Neuchatel, Switzerland

P117: Serum proteomic analysis characterises newly diagnosed Crohn’s disease and ulcerative colitis depending on the age at diagnosisECCO '18 Vienna
Year: 2018
Authors:

S. Verstockt1*, E. Glorieus2, M. De Decker3, B. Verstockt4,5, N. Ardeshir Davani5, V. Ballet4, G. Van Assche4,5, P. Hindryckx2, M. Ferrante4,5, D. Laukens2, F. Mana3, M. De Vos2, S. Vermeire4,5, I. Cleynen1

1University of Leuven, Department of Human Genetics, Laboratory for Complex Genetics, Leuven, Belgium, 2University Hospital Ghent, Department of Gastroenterology, Ghent, Belgium, 3University Hospital Brussels, Department of Gastroenterology, Brussels, Belgium, 4University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, 5University of Leuven, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), Leuven, Belgium

P118: Identification of colitis-associated bacteria in intestine of inflammatory bowel disease patientsECCO '18 Vienna
Year: 2018
Authors:

J. Seishima*, N. Iida, E. Mizukoshi, S. Kaneko

Graduate School of Medicine, Kanazawa University, Gastroenterology, Kanazawa, Ishikawa, Japan

P119: The immunohistochemical assessment of CD30+ lymphocytes in the intestinal mucosa facilitates diagnosis of paediatric ulcerative colitisECCO '18 Vienna
Year: 2018
Authors:

O. Fabian1*, O. Hradsky2, T. Drskova3, F. Mikus1, J. Zamecnik1, J. Bronsky3

1Motol University Hospital, Department of Pathology and Molecular Medicine, Prague, Czech Republic, 2Motol University Hospital, – Department of Paediatrics, Prague, Czech Republic, 3Motol University Hospital, Department of Paediatrics, Prague, Czech Republic

P120: Vitamin D deficiency in Crohn’s diseaseECCO '18 Vienna
Year: 2018
Authors:

C. Haifer1*, R.M. Lucas2, M.W. Clarke3, I. Lawrance4,5, P.H. Hart6, J.R. Center7,8, J.A. Eisman7,8, S. Ghaly1

1St Vincent's Hopspital, Sydney, Gastroenterology, Sydney, Australia, 2The Australian National University, National Centre for Epidemiology and Population Health, Canberra, Australia, 3The University of Western Australia, Centre for Microscopy, Characterisation and Analysis, Perth, Australia, 4University of Western Australia, School of Medicine and Pharmacology, Faculty of Health and Medical Sciences, Perth, Australia, 5St John of God Hospital, Centre for Inflammatory Bowel Diseases, Subiaco, Australia, 6Telethon Kids Institute, Inflammation, Subiaco, Australia, 7The Garvan Institute of Medical Research, Osteoporosis and Bone Biology, Sydney, Australia, 8St Vincent's Hospital Sydney, Endocrinology, Sydney, Australia

P121: Characterising and managing issues with food-related quality of life in inflammatory bowel disease: a qualitative study of patients and healthcare professionalsECCO '18 Vienna
Year: 2018
Authors:

W. Czuber-Dochan1*, M. Morgan2, M. Lomer1, J.O. Lindsay3, G. Robert4, K. Whelan1

1King's College London, Faculty of Life Sciences and Medicine, Department of Nutritional Sciences, London, UK, 2King's College London, Institute of Pharmacological Sciences, London, UK, 3Bart’s and the London NHS Trust, Gastroenterology Department, London, UK, 4King's College London, Faculty of Nursing, Midwifery and Palliative Care, London, UK

P122: Vitamin D activates human intestinal fibroblastsECCO '18 Vienna
Year: 2018
Authors:

L. Gisbert-Ferrándiz1*, P. Salvador1, D.C. Macias-Ceja2, J. Cosín-Roger2, D. Ortiz-Masiá3,4, F. Navarro-Vicente5, S. Calatayud1,4, C. Hernández2, M.D. Barrachina1,4

1University of Valencia, Pharmacology, Valencia, Spain, 2Fisabio Hospital Dr Peset, Valencia, Spain, 3University of Valencia, Medicine, Valencia, Spain, 4CIBERehd, Valencia, Spain, 5Hospital of Manises, Servicio de Cirugía, Valencia, Spain

P123: The effect of necrosis inhibition on acute DSS colitis model of inflammatory bowel diseaseECCO '18 Vienna
Year: 2018
Authors:

D. Lee1,2*, J.S. Koo2, C.H. Kim1, S.H. Hwang1, J.W. Choe2, S.Y. Kim2, S.W. Jung2, H.J. Yim2, Y.T. Jeen2, S.W. Lee2

1Korea University Ansan Hospital, Internal Medicine, Seoul, South Korea, 2Korea University College of Medicine, Seoul, South Korea

P124: An investigation of taste preference to oral nutritional supplement drinks (ONS) in adolescent and adult Crohn’s disease (CD) and attitudes towards their long-term useECCO '18 Vienna
Year: 2018
Authors:

K. Keetarut1*, N. Richards2, N. Davies3

1University College London Hospital, Nutrition and Dietetics, London, UK, 2University College London, London, UK, 3University College London, London, UK

P125: Basement membrane remodelling as a biomarker for monitoring disease activity in Crohn’s disease patients: the role of lamininECCO '18 Vienna
Year: 2018
Authors:

M.L. Olesen1,2*, A. Di Sabatino3,4, G. Mazza4, T. Manon-Jensen1, P. Giuffrida3, M. Pinzani4, A. Krag2, M. Karsdal1, J. Kjeldsen2, J.H. Mortensen1

1Nordic Bioscience A/S, Biomarkers and Research, Herlev, Denmark, 2University of Southern Denmark and Odense University Hospital, Department of Medical Gastroenterology, Odense, Denmark, 3San Matteo Hospital Foundation and University of Pavia, Department of Internal Medicine, Pavia, Italy, 4University College of London, Institute for Liver and Digestive Health, London, UK