¹Wroclaw Medical University, Department of Gastroenterology and Hepatology, Wroclaw, Poland, ²Wroclaw Medical University, Department of Medical Biochemistry, Wroclaw, Poland

University Hospital Zurich, University of Zurich, Gastroenterology and Hepatology, Zurich, Switzerland

¹Rijnstate Crohn and Colitis Centre, Department of Gastroenterology and Hepatology, Arnhem, The Netherlands, ²Rijnstate Hospital, Department of Microbiology and Immunology, Arnhem, The Netherlands

¹CHA University, Gastroenterology, Seongnam, South Korea, ²CHA Cancer preventive Research center, Seongnam, South Korea, ³CHA University, Seongnam, South Korea

¹Unit of Pathology, “Villa Sofia-Cervello” Hospital, Palermo, Italy, ²Division of Internal Medicine, “Villa Sofia-Cervello” Hospital, Palermo, Italy, ³Gastroenterology and Endoscopy Unit, “Villa Sofia-Cervello” Hospital, Palermo, Italy

¹University of Antwerp, Laboratory of Experimental Medicine and Pediatrics, Antwerp, Belgium, ²Antwerp University Hospital, Gastroenterology and Hepatology, Antwerp, Belgium

¹Nordic Bioscience A/S, Herlev, Denmark, ²Odense University Hospital, Department of Medical Gastroenterology, Odense, Denmark, ³Lillebaelt Hospital Vejle, Department of Internal Medicine, Section of Gastroenterology, Vejle, Denmark

¹Norwegian University of Science and Technology, Department of Clinical and Molecular Medicine, Trondheim, Norway, ²Norwegian University of Science and Technology, Centre of Molecular Inflammation Research (CEMIR), Trondheim, Norway, ³St. Olav’s University Hospital, Department of Infectious Diseases, Trondheim, Norway, ⁴St. Olav’s University Hospital, Trondheim, Department of Gastroenterology and Hepatology, Trondheim, Norway, ⁵St. Olav’s University Hospital, Trondheim, Clinic of Medicine, Trondheim, Norway, ⁶University of Oslo, K.G Jebsen Inflammation Research Center, Oslo, Norway, ⁷Oslo University Hospital Rikshospitalet and Univesity of Oslo, Department of Immunology, Oslo, Norway, ⁸Nordland Hospital, Research Laboratory, Bodø, Norway, ⁹University of Tromsø, K.G. Jebsen Thrombosis Research and Expertise Center, Institute of Clinical Medicine, Tromsø, Norway

¹Centre for Molecular Medicine and Stem Cell research, Faculty of Medical Sciences University of Kragujevac Serbia, Department of Microbiology and Immunology, Kragujevac, Serbia, ²Faculty of Medical Sciences, University of Kragujevac Serbia, Department of Dentistry, Kragujevac, Serbia, ³Faculty of Medical Sciences, University of Kragujevac Serbia, Department of Psychology, Kragujevac, Serbia

¹Erasmus MC, Laboratory of Pediatrics, division Gastroenterology and Nutrition, Rotterdam, The Netherlands, ²INSERM, Institut Imagine and Université Paris-Descartes, Laboratory of Intestinal Immunity, Paris, France, ³Poznan University of Medical Sciences, Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan, Poland, ⁴Leiden University Medical Center (LUMC), Department of Paediatric Gastroenterology, Leiden, The Netherlands, ⁵Erasmus Medical Center Children's Hospital, Department of Paediatric Gastroenterology, Rotterdam, The Netherlands

¹Hospital of the Ludwig Maximilian Universität, General-, Visceral and Transplantation surgery, Munich, Germany, ²Ludwig Maximilian Universität, Institute of Molecular Animal Breeding and Biotechnology, and Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, Munich, Germany, ³Austrian Institute of Technology, Vienna, Austria, ⁴Hospital of the Ludwig Maximilian Universität, Medicine II-Grosshadern, Munich, Germany

¹Kyungpook National University School of Medicine, Internal Medicine, Daegu, South Korea, ²Yeungnam University College of Pharmacy, Pharmacy, Daegu, South Korea, ³Hanyang University College of Pharmacy, Pharmacy, Ansan, South Korea

First Affiliated Hospital of Nanjing Medical University, Department of Gastroenterology, Nanjing, China

¹Nottingham Digestive Diseases Centre, School of Medicine, University of Nottingham UK, Nottingham, UK, ²National Institute of Health Research (NIHR) Biomedical Research Centre in Gastrointestinal and Liver Diseases at Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, UK, ³Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham UK, Nottingham, UK, ⁴Centre for Medical Imaging, Division of Medicine, UCL UK, London, UK

¹University of Palermo, Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Palermo, Italy, ²University of Palermo, Advanced Technologies Network (ATeN) Center, Palermo, Italy, ³University of Palermo, Palermo, Italy, ⁴Institute of Biomedicine and Molecular Immunology "Alberto Monroy" (IBIM), Consiglio Nazionale delle Ricerche (CNR), Palermo, Italy

¹University of Padova, Department of Surgery, Oncology and Gastroenterology, Padova, Italy, ²IRCCS IOV Istituto Oncologico Veneto, Padova, Italy, ³Azienda Ospedaliera - Università di Padova, Padova, Italy, ⁴University of Padova, Department of Medicine, Padova, Italy, ⁵University of Padova, Department of Molecular Medicine, Padova, Italy

University Medical Center of Groningen, Groningen, The Netherlands

¹Tokyo Medical and Dental University, Gastroenterology and Hepatology, Tokyo, Japan, ²Tokyo Medical and Dental University, Center for Stem Cell and Regenerative Medicine, Tokyo, Japan, ³Tokyo Medical and Dental University, Advanced Therapeutics for Gastrointestinal Diseases, Tokyo, Japan

¹University of Leuven, Department of Human Genetics, Laboratory for Complex Genetics, Leuven, Belgium, ²University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, ³University of Leuven, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), Leuven, Belgium, ⁴University of Leuven, Department of Human Genetics, Leuven, Belgium, ⁵University Hospitals Leuven, Genomics Core, Leuven, Belgium, ⁶University Hospital Ghent, Department of Gastroenterology, Ghent, Belgium, ⁷University Hospital Brussels, Department of Gastroenterology, Brussels, Belgium

¹Blizard Institute, Barts and the London School of Medicine and Dentistry, Centre for Immunobiology, London, UK, ²Barts Health, London, UK, ³Instituto de Estudios Inmunológicos y Fisiopatológicos-IIFP-CONICET-Universidad Nacional de La Plata, La Plata, Argentina