¹Academic Medical Centre, Amsterdam, The Netherlands, ²Medical University of Vienna, Vienna, Austria, ³University of Washington, Seattle, USA, ⁴Clinic of Gastroenterology and Hepatology, Military Medical Academy, Belgrade, Serbia, ⁵University Hospital CHU of Liège, Liège, Belgium, ⁶Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland, ⁷Universitatsklinikum Ulm, Ulm, Germany, ⁸University Hospital Schleswig-Holstein, Christian-Albrechts-University, Kiel, Germany, ⁹Kangbuk Samsung Hospital, Sungkyunkwan University, Seoul, South Korea, ¹⁰Université de Nice Sophia Antipolis, Hôpital de l’Archet, Nice, France, ¹¹Shire, Lexington, USA, ¹²Pfizer, Cambridge, USA, ¹³Zymo Consulting Group, Newtown Square, USA, ¹⁴University of California San Diego, La Jolla, USA

¹Indiana University, Indianapolis, USA, ²Mayo Clinic, Rochester, USA, ³University of California - San Diego, La Jolla, USA, ⁴Montefiore Medical Center, New York, USA, ⁵Cleveland Clinic Foundation, Cleveland, USA, ⁶Icahn School of Medicine at Mount Sinai, New York, USA, ⁷Dartmouth-Hitchcock Medical Center, Lebanon, USA, ⁸Takeda Pharmaceuticals U.S.A., Inc., Deerfield, USA, ⁹New York University (NYU), New York, USA, ¹⁰North Shore University Hospital, Manhasset, USA, ¹¹Lenox Hill Hospital, New York, USA, ¹²University of Mississippi, Jackson, USA

¹Icahn School of Medicine at Mount Sinai, New York, USA, ²Cleveland Clinic Foundation, Cleveland, USA, ³University of California – San Diego, La Jolla, USA, ⁴Indiana University, Indianapolis, USA, ⁵Montefiore Medical Center, New York, USA, ⁶Mayo Clinic, Rochester, USA, ⁷Dartmouth-Hitchcock Medical Center, Lebanon, USA, ⁸Takeda Pharmaceuticals U.S.A., Inc., Deerfield, USA, ⁹New York University (NYU), New York, USA, ¹⁰North Shore University Hospital, Manhasset, USA, ¹¹Lenox Hill Hospital, New York, USA, ¹²University of Mississippi, Jackson, USA

¹Fisabio, Hospital Dr Peset, Valencia, Spain, ²University of Valencia, Valencia, Spain, ³University of Zurich, Gastroenterology, Zurich, Switzerland

¹University Medical Center Groningen, Gastroenterology and Hepatology, Groningen, The Netherlands, ²The Broad Institute of MIT and Harvard, Cambridge, USA

¹Technical University Munich, III. Medizinische Klinik, Munich, Germany, ²Ludwig-Maximilian University of Munich, Department for Cell Biology, Munich, Germany, ³Technical University Munich, Institut for Pathologie, Munich, Germany

¹University Hospital Zurich, Division of Gastroenterology and Hepatology, Zurich, Switzerland, ²University of Zurich, Institute of Experimental Immunologx, Zurich, Switzerland

¹University of Exeter, IBD Pharmacogenetics, Exeter, UK, ²Abbvie, Chicago, USA, ³St Mark’s Hospital, IBD Unit, London, UK

¹University Hospitals Leuven, Department of Gastroenterology and Hepatology, Leuven, Belgium, ²KU Leuven, Department of Chronic Diseases, Metabolism and Ageing, Leuven, Belgium, ³University Hospitals Leuven, Department of Paediatric gastroenterology, Leuven, Belgium, ⁴Ziekenhuis Oost-Limburg-Campus Sint-Jan, Department of Gastroenterology and Hepatology, Genk, Belgium, ⁵CHU UCL Namur, Université catholique de Louvain, Yvoir, Belgium, ⁶Imeldaziekenhuis, Department of Gastroenterology and Hepatology, Bonheiden, Belgium, ⁷Mariaziekenhuis Noord-Limburg, Department of Gastroenterology and Hepatology, Overpelt, Belgium, ⁸Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium, ⁹University Hospital Antwerp, Department of Gastroenterology and Hepatology, Antwerp, Belgium, ¹⁰Sint-Trudo Ziekenhuis, Department of Gastroenterology and Hepatology, Sint-Truiden, Belgium, ¹¹AZ Vesalius, Department of Gastroenterology and Hepatology, Tongeren, Belgium, ¹²AZ Klina, Department of Gastroenterology and Hepatology, Brasschaat, Belgium, ¹³AZ Groeninge, Department of Gastroenterology and Hepatology, Kortrijk, Belgium

¹Icahn School of Medicine at Mount Sinai, Dr. Henry D. Janowitz Division of Gastroenterology, New York, NY, USA, ²UC San Diego School of Medicine, Division of Cardiovascular Medicine, La Jolla, CA, USA, ³Western University, Robarts Clinical Trials, London, ON, Canada, ⁴Presidio Columbus Fondazione Policlinico Gemelli Università Cattolica, IBD Unit, Rome, Italy, ⁵Pfizer Inc., Collegeville, PA, USA

¹Hospital Son Llàtzer, Palma, Spain, ²Universitat Autònoma de Barcelona, Barcelona, Spain, ³Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ⁴CIBERehd Instituto de Salud Carlos III, Madrid, Spain, ⁵Hospital Clínic, Barcelona, Spain, ⁶Hospital Reina Sofia, Córdoba, Spain, ⁷Hospital Puerta de Hierro, Majadahonda, Spain, ⁸Hospital Bellvitge, L’Hospitalet de Llobregat, Spain, ⁹Hospital Clínico San Carlos, Madrid, Spain, ¹⁰Hospital La Fe, Valencia, Spain, ¹¹Hospital Ramón y Cajal, Madrid, Spain, ¹²Hospital La Paz, Madrid, Spain, ¹³Hospital Clínico de Valencia, Valencia, Spain, ¹⁴Hospital La Princesa, Madrid, Spain, ¹⁵Hospital Universitario Miguel Servet, Zaragoza, Spain, ¹⁶Hospital Universitario Central de Asturias, Oviedo, Spain, ¹⁷Hospital Clínico Lozano Blesa, Zaragoza, Spain, ¹⁸Hospital Parc Taulí, Sabadell, Spain, ¹⁹Hospital Santa Creu i Sant Pau, Barcelona, Spain, ²⁰Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²¹Complexo Hospital Universitario de Vigo, Vigo, Spain, ²²Hospital Virgen de la Macarena, Sevilla, Spain, ²³Hospital Universitario Burgos, Burgos, Spain, ²⁴Hospital Río Hortega, Valladolid, Spain, ²⁵Hospital Mutua de Terrassa, Terrassa, Spain, ²⁶Hospital del mar, Barcelona, Spain, ²⁷Hospital General Universitario de Alicante, Alicante, Spain, ²⁸Hospital Clínico de Málaga, Málaga, Spain, ²⁹Hospital 12 de octubre, Madrid, Spain, ³⁰Hospital Universitario Fundación Alcorcón, Alcorcón, Spain, ³¹Hospital Dr Josep Trueta, Girona, Spain, ³²Hospital General Universitario de Elche, Elche, Spain, ³³Hospital General de Ciudad Real, Ciudad Real, Spain, ³⁴Hospital Universitario Fuenlabrada, Fuenlabrada, Spain, ³⁵Hospital Manises, Manises, Spain, ³⁶Consorci sanitari de Terrassa, Terrassa, Spain, ³⁷Hospital Santa Lucía, Cartagena, Spain, ³⁸Hospital Clínico Universitario Valladolid, Valladolid, Spain, ³⁹CH de Navarra, Pamplona, Spain, ⁴⁰Hospital Universitario de Salamanca, Salamanca, Spain, ⁴¹Hospital de Cruces, Barakaldo, Spain, ⁴²Hospital Galdakao, Galdakao, Spain, ⁴³Instituto Biodonostia UPV/EHU, (Donostia, Spain, ⁴⁴Hospital San Jorge, Huesca, Spain, ⁴⁵Hospital Nuestra Sra Candelaria, Sta Cruz Tenerife, Spain, ⁴⁶Hospital Mancha Centro, Alcazar de San Juan, Spain, ⁴⁷Hospital General Universitario Valencia, Valencia, Spain, ⁴⁸Hospital Moisès Broggi, St Joan Despí, Spain, ⁴⁹CH Santiago, Santiago de Compostela, Spain, ⁵⁰CH de Palencia, Palencia, Spain, ⁵¹Hospital Universitario de Canarias, La Laguna, Spain, ⁵²Hospital Torrejón, Torrejón, Spain, ⁵³HG de Castelló, Castelló, Spain, ⁵⁴Hospital Sant Joan de Déu-Althaia, Manresa, Spain, ⁵⁵Hospital General de Tomelloso, Tomelloso, Spain, ⁵⁶Hospital Basurto, Bilbao, Spain, ⁵⁷Hospital Viladecans, Viladecans, Spain, ⁵⁸Hospital Royo Vilanova, Zaragoza, Spain, ⁵⁹Hospital General, Segovia, Spain, ⁶⁰Hospital Son Espases, Palma, Spain, ⁶¹Hospital Arnau de Vilanova, Lleida, Spain, ⁶²Complejo Hospitalario de Jaén, Jaén, Spain

¹University of Exeter, IBD Pharmacogenetics, Exeter, UK, ²Royal Devon and Exeter NHS Foundation Trust, Department of Gastroenterology, Exeter, UK, ³University of Exeter, Exeter Medical School Bioinformatics Team, Exeter, UK, ⁴University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, The Netherlands, ⁵The Broad Institute of MIT and Harvard, Cambridge, USA, ⁶Massachusetts General Hospital, Analytical and Translational Genetics Unit, Boston, USA, ⁷Hôpital Saint-Antoine, Service de Gastroentérologie et Nutrition, Paris, France, ⁸Cedars-Sinai Medical Center, Inflammatory Bowel Disease Center, Division of Gastroenterology, Los Angeles, USA

¹Radboud University Nijmegen Medical Centre, Gastroenterology and Hepatology, Nijmegen, The Netherlands, ²Jeroen Bosch Hospital, Gastroenterology and Hepatology, S Hertogenbosch, The Netherlands, ³Radboud University Nijmegen Medical Centre, Pathology, Nijmegen, The Netherlands

¹University Hospital Zurich, Division of Gastroenterology and Hepatology, Zurich, Switzerland, ²University Hospital Lausanne - CHUV, Institute of Social and Preventive Medicine, Lausanne, Switzerland

¹University of Erlangen-Nuremberg, Department of Medicine I, Erlangen, Germany, ²Academic Medical Center, Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands

¹Tokyo Medical and Dental University, Center for Stem Cell and Regenerative Medicine, Tokyo, Japan, ²Tokyo Medical and Dental University, Advanced Therapeutics for Gastrointestinal Diseases, Tokyo, Japan, ³Tokyo Medical and Dental University, Department of Gastroenterology and Hepatology, Tokyo, Japan

¹Blizard Institute, London, UK, ²Barts Health NHS Trust, Histopathology, London, UK, ³Barts Health NHS Trust, Gastroenterology, London, UK

¹The University of Liverpool, Cellular and Molecular Physiology, Liverpool, UK, ²Royal Liverpool and Broadgreen University Hospital Trust, Liverpool, UK, ³University of Manchester, Department of Immunology, Manchester, UK, ⁴GeneXplain, Wolfenbüttel, Germany

¹Natural Products and Medicinal Chemistry Research Group, Department of pharmacy, University of Tromsø The Arctic University of Norway, Tromsø, Norway, ²Swedish Metabolomics Center, Swedish University of Agricultural Sciences, Umeå, Sweden, ³Research Group of Gastroenterology and Nutrition, Department of Clinical Medicine, University of Tromsø The Arctic University of Norway, Tromsø, Norway

¹Translational Research center for GastroIntestinal Disorders (TARGID), Chronic Diseases, Metabolism and Ageing (CHROMETA), Leuven, Belgium, ²Rega Institute for Medical Research, Microbiology and Immunology, Leuven, Belgium, ³McGill University, Gastroenterology, Montreal, Canada, ⁴Prometheus Laboratories, Research and Development, San Diego, USA, ⁵Hasselt University/Jessa Hospital, Faculty of Medicine and Life Sciences, Hasselt, Belgium, ⁶University Hospitals Leuven, Gastroenterology and Hepatology, Leuven, Belgium